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127 Results Found

  • Feature Paper
  • Article
  • Open Access
9 Citations
2,976 Views
14 Pages

Hot Corrosion Behavior of TWAS and HVOF NiCr-Based Coatings in Molten Salt

  • Kateřina Lencová,
  • Marie Frank Netrvalová,
  • Marek Vostřák,
  • František Lukáč,
  • Radek Mušálek,
  • Zdeněk Česánek and
  • Šárka Houdková

18 February 2023

In order to extend the life of boilers by applying an anti-corrosion coating without the need to dismantle them, it is advisable to find coatings that can be applied using cheaper and portable techniques, such as Twin Wire Arc Spray technology (TWAS)...

  • Systematic Review
  • Open Access
13 Citations
5,749 Views
21 Pages

Total Wrist Arthroplasty—A Systematic Review of the Outcome, and an Introduction of FreeMove—An Approach to Improve TWA

  • Jörg Eschweiler,
  • Jianzhang Li,
  • Valentin Quack,
  • Björn Rath,
  • Alice Baroncini,
  • Frank Hildebrand and
  • Filippo Migliorini

11 March 2022

The Swanson silicone prosthesis was one of the first devices to realize total wrist arthroplasty (TWA). It has been used regularly since the early 1960s. This systematic review of the literature evaluated the status quos of TWA. The present study was...

  • Article
  • Open Access
6 Citations
5,547 Views
16 Pages

Water samples were collected and analyzed for conductivity, pH, temperature and trihalomethanes (THMs) during the fall of 2014 at two monitored municipal drinking water source ponds. Both spot (or grab) and time weighted average (TWA) sampling method...

  • Article
  • Open Access
5 Citations
4,562 Views
11 Pages

Broadband amplifiers are essential building blocks used in high data rate wireless, radar, and instrumentation systems, as well as in optical communication systems. Only a traveling-wave amplifier (TWA) provides sufficient bandwidth for broadband app...

  • Article
  • Open Access
2,381 Views
15 Pages

25 February 2023

Transcriptome-wide association studies (TWASs) aim to detect associations between genetically predicted gene expression and complex diseases or traits through integrating genome-wide association studies (GWASs) and expression quantitative trait loci...

  • Article
  • Open Access
8 Citations
3,505 Views
17 Pages

Sewage scum (SS) is collected from sedimentation tanks in wastewater treatment plants (WWTPs). Despite its huge biogas potential, there is limited information on its potential as a co-substrate and microbial ecology, especially during anaerobic co-di...

  • Article
  • Open Access
5 Citations
4,236 Views
17 Pages

A Transcriptome-Wide Analysis of Psoriasis: Identifying the Potential Causal Genes and Drug Candidates

  • Yeonbin Jeong,
  • Jaeseung Song,
  • Yubin Lee,
  • Eunyoung Choi,
  • Youngtae Won,
  • Byunghyuk Kim and
  • Wonhee Jang

Psoriasis is a chronic inflammatory skin disease characterized by cutaneous eruptions and pruritus. Because the genetic backgrounds of psoriasis are only partially revealed, an integrative and rigorous study is necessary. We conducted a transcriptome...

  • Article
  • Open Access
5 Citations
3,111 Views
17 Pages

Transcriptome-Wide Association Study Reveals Potentially Candidate Genes Responsible for Milk Production Traits in Buffalo

  • Kelong Wei,
  • Ying Lu,
  • Xiaoya Ma,
  • Anqian Duan,
  • Xingrong Lu,
  • Hamdy Abdel-Shafy and
  • Tingxian Deng

23 February 2024

Identifying key causal genes is critical for unraveling the genetic basis of complex economic traits, yet it remains a formidable challenge. The advent of large-scale sequencing data and computational algorithms, such as transcriptome-wide associatio...

  • Article
  • Open Access
11 Citations
6,222 Views
21 Pages

Transcriptome-Wide Association Study of Blood Cell Traits in African Ancestry and Hispanic/Latino Populations

  • Jia Wen,
  • Munan Xie,
  • Bryce Rowland,
  • Jonathan D. Rosen,
  • Quan Sun,
  • Jiawen Chen,
  • Amanda L. Tapia,
  • Huijun Qian,
  • Madeline H. Kowalski and
  • Yun Li
  • + 26 authors

8 July 2021

Background: Thousands of genetic variants have been associated with hematological traits, though target genes remain unknown at most loci. Moreover, limited analyses have been conducted in African ancestry and Hispanic/Latino populations; hematologic...

  • Article
  • Open Access
11 Citations
5,476 Views
18 Pages

23 January 2019

Finding farm-proven, robust sampling technologies for measurement of odorous volatile organic compounds (VOCs) and evaluating the mitigation of nuisance emissions continues to be a challenge. The objective of this research was to develop a new method...

  • Article
  • Open Access
7 Citations
3,415 Views
11 Pages

23 December 2022

Several genes associated with periodontitis have been identified through genome-wide association studies (GWAS); however, known genes only explain a minority of the estimated heritability. We aimed to explore more susceptibility genes and the underly...

  • Article
  • Open Access
3 Citations
5,086 Views
22 Pages

27 December 2021

In the twin wire arc spraying (TWAS) process, it is common to use compressed air as atomizing gas. Nitrogen or argon also are used to reduce oxidation and improve coating performance. The heat required to melt the feedstock material depends on the el...

  • Article
  • Open Access
1 Citations
2,708 Views
18 Pages

26 October 2024

Endometriosis (EMT) is a common gynecological disease with a strong genetic component, while its precise etiology remains elusive. This study aims to integrate transcriptome-wide association study (TWAS), Mendelian randomization (MR), and bioinformat...

  • Article
  • Open Access
1 Citations
2,532 Views
18 Pages

Comparison of Optimization Strategies for Musculoskeletal Modeling of the Wrist for Therapy Planning in Case of Total Wrist Arthroplasty

  • Jörg Eschweiler,
  • Maximilian Praster,
  • Valentin Quack,
  • Jianzhang Li,
  • Björn Rath,
  • Frank Hildebrand and
  • Filippo Migliorini

2 April 2022

The human wrist joint is an elegant mechanism. The wrist allows the positioning and orienting of the hand to the forearm. The computational modeling of the human hand, especially of the wrist joint, can reveal important information about biomechanica...

  • Article
  • Open Access
639 Views
14 Pages

Integrative Multi-Omics Analysis Unveils Candidate Genes and Functional Variants for Growth and Reproductive Traits in Duroc Pigs

  • Zhuofan Yan,
  • Xiyue Li,
  • Wenbo Yang,
  • Peng Zhou,
  • Weiya Zhang,
  • Xinyun Li,
  • Liangliang Fu,
  • Jingjin Li and
  • Xiaoyong Du

17 December 2025

Pigs play a vital role in global food security as a major source of animal protein. Enhancing growth and reproductive traits is of great economic importance to the swine industry. To systematically identify genetic determinants underlying key economi...

  • Article
  • Open Access
2 Citations
3,081 Views
12 Pages

15 April 2022

Partial occlusion and background clutter in camera video surveillance affect the accuracy of video-based person re-identification (re-ID). To address these problems, we propose a person re-ID method based on random erasure of frame sampling and tempo...

  • Article
  • Open Access
12 Citations
4,712 Views
17 Pages

Integration of eQTL Analysis and GWAS Highlights Regulation Networks in Cotton under Stress Condition

  • Xiao Han,
  • Chenxu Gao,
  • Lisen Liu,
  • Yihao Zhang,
  • Yuying Jin,
  • Qingdi Yan,
  • Lan Yang,
  • Fuguang Li and
  • Zhaoen Yang

The genus Gossypium is one of the most economically important crops in the world. Here, we used RNA-seq to quantify gene expression in a collection of G. arboreum seedlings and performed eGWAS on 28,382 expressed genes. We identified a total of 30,08...

  • Article
  • Open Access
5 Citations
3,419 Views
14 Pages

1 November 2021

High-density lipoprotein (HDL) cholesterol levels are closely associated with human health and diseases. To identify genes modulating plasma HDL levels, we integrated HDL measurements and multi-omics data collected from diverse mouse cohorts and comb...

  • Article
  • Open Access
3 Citations
3,516 Views
15 Pages

Meat color traits directly influence consumer acceptability and purchasing decisions. Nevertheless, there is a paucity of comprehensive investigation into the genetic mechanisms underlying meat color traits in pigs. Utilizing genome-wide association...

  • Article
  • Open Access
1 Citations
1,284 Views
14 Pages

The Effect of Intraoperative Hypothermia on Anastomotic Leakage After Esophagectomy

  • Lorenzo Cinelli,
  • Stefano Turi,
  • Francesco Puccetti,
  • Yong-Ha Lee,
  • Riccardo Rosati,
  • Ugo Elmore and
  • on behalf of the OSR CCeR Collaborative Group

30 March 2025

Background/Objectives: Inadvertent intraoperative hypothermia is a common occurrence during major surgery, and some preclinical studies have reported its association with postoperative anastomotic leakage (AL). In the present study, we demonstrated t...

  • Article
  • Open Access
9 Citations
3,567 Views
13 Pages

Brain Proteome-Wide Association Study Identifies Candidate Genes that Regulate Protein Abundance Associated with Post-Traumatic Stress Disorder

  • Zhen Zhang,
  • Peilin Meng,
  • Huijie Zhang,
  • Yumeng Jia,
  • Yan Wen,
  • Jingxi Zhang,
  • Yujing Chen,
  • Chun’e Li,
  • Chuyu Pan and
  • Feng Zhang
  • + 4 authors

27 July 2022

Although previous genome-wide association studies (GWASs) on post-traumatic stress disorder (PTSD) have identified multiple risk loci, how these loci confer risk of PTSD remains unclear. Through the FUSION pipeline, we integrated two human brain prot...

  • Article
  • Open Access
1 Citations
726 Views
15 Pages

A Structured Low-Intensity Home-Based Walking Program to Improve Physical and Mental Functioning After Hospitalization for Severe COVID-19: A Pragmatic Nonrandomized Controlled Trial

  • Nicola Lamberti,
  • Andrea Baroni,
  • Giovanni Piva,
  • Giulia Fregna,
  • Nicola Schincaglia,
  • Anna Crepaldi,
  • Lorenzo Gamberini,
  • Antonella Occhi,
  • Sofia Straudi and
  • Fabio Manfredini

30 September 2025

Background/Objectives: We aimed to test whether home-based low-intensity interval training (LIIT) could be equally or more effective than traditional continuous walking advice (TWA) in a population hospitalized and healed from severe COVID-19. Method...

  • Article
  • Open Access
4 Citations
3,020 Views
10 Pages

22 June 2022

Recently, gene-based association studies have shown that integrating genome-wide association studies (GWAS) with expression quantitative trait locus (eQTL) data can boost statistical power and that the genetic liability of traits can be captured by p...

  • Article
  • Open Access
35 Citations
6,446 Views
30 Pages

Enhanced Robot Motion Block of A-Star Algorithm for Robotic Path Planning

  • Raihan Kabir,
  • Yutaka Watanobe,
  • Md Rashedul Islam and
  • Keitaro Naruse

22 February 2024

An optimized robot path-planning algorithm is required for various aspects of robot movements in applications. The efficacy of the robot path-planning model is vulnerable to the number of search nodes, path cost, and time complexity. The conventional...

  • Article
  • Open Access
4 Citations
2,417 Views
14 Pages

Cognitive Impairment in Nonagenarians: Potential Metabolic Mechanisms Revealed by the Synergy of In Silico Gene Expression Modeling and Pathway Enrichment Analysis

  • Aleksandra Mamchur,
  • Elena Zelenova,
  • Irina Dzhumaniiazova,
  • Veronika Erema,
  • Daria Kashtanova,
  • Mikhail Ivanov,
  • Maria Bruttan,
  • Mariia Gusakova,
  • Mikhail Terekhov and
  • Sergey Yudin
  • + 12 authors

Previous studies examining the molecular and genetic basis of cognitive impairment, particularly in cohorts of long-living adults, have mainly focused on associations at the genome or transcriptome level. Dozens of significant dementia-associated gen...

  • Article
  • Open Access
2 Citations
894 Views
15 Pages

Prognostic Role of Electrocardiographic Alternans in Ischemic Heart Disease

  • Ilaria Marcantoni,
  • Erica Iammarino,
  • Alessandro Dell’Orletta and
  • Laura Burattini

11 April 2025

Background/Objectives: Noninvasive arrhythmic risk stratification in patients with ischemic heart disease is poor nowadays, and further investigations are needed. The most correct approach is based on the use of electrocardiogram (ECG) with the extra...

  • Article
  • Open Access
2 Citations
2,253 Views
13 Pages

Genome-Wide and Transcriptome-Wide Association Analysis Identifies qRS-6D and Its Candidate Genes Regulating Root Development of Wheat Seedlings

  • Mingzhu Cheng,
  • Pengcheng Wang,
  • Xueting Liu,
  • Zhiwei Zhu,
  • Sichun Qiu,
  • Yuxiu Liu,
  • Xue Shi,
  • Wanquan Ji,
  • Shengbao Xu and
  • Xiaoming Wang

19 May 2024

Wheat (Triticum aestivum L.) is one of the most important cereal crops worldwide, and its production is challenged by global climate change and a shortage of resources. The root system plays a vital role in uptaking water and nutrients and sensing so...

  • Review
  • Open Access
20 Citations
5,146 Views
13 Pages

Learning from Fifteen Years of Genome-Wide Association Studies in Age-Related Macular Degeneration

  • Tobias Strunz,
  • Christina Kiel,
  • Bastian L. Sauerbeck and
  • Bernhard H. F. Weber

10 October 2020

Over the last 15 years, genome-wide association studies (GWAS) have greatly advanced our understanding of the genetic landscape of complex phenotypes. Nevertheless, causal interpretations of GWAS data are challenging but crucial to understand underly...

  • Review
  • Open Access
2 Citations
2,197 Views
18 Pages

Normalization of Electrocardiogram-Derived Cardiac Risk Indices: A Scoping Review of the Open-Access Literature

  • Erica Iammarino,
  • Ilaria Marcantoni,
  • Agnese Sbrollini,
  • Micaela Morettini and
  • Laura Burattini

16 October 2024

Changes in cardiac function and morphology are reflected in variations in the electrocardiogram (ECG) and, in turn, in the cardiac risk indices derived from it. These variations have led to the introduction of normalization as a step to compensate fo...

  • Article
  • Open Access
1 Citations
1,855 Views
12 Pages

Non-Invasive Risk Assessment and Prediction of Mortality in Patients Undergoing Coronary Artery Bypass Graft Surgery

  • Ju-Youn Kim,
  • Young-Jun Park,
  • Kyoung-Min Park,
  • Young-Keun On,
  • June-Soo Kim,
  • Seung-Jung Park and
  • Young-Tak Lee

Objectives: Heart rate turbulence (HRT) and T-wave alternans (TWA), non-invasive markers of cardiac autonomic dysfunction, and ventricular repolarization abnormality, reportedly, predict the risk of cardiovascular death after myocardial infarction. W...

  • Article
  • Open Access
9 Citations
3,417 Views
14 Pages

Hypotension Prediction Index and Incidence of Perioperative Hypotension: A Single-Center Propensity-Score-Matched Analysis

  • Julian Runge,
  • Jessica Graw,
  • Carla D. Grundmann,
  • Thomas Komanek,
  • Jan M. Wischermann and
  • Ulrich H. Frey

23 August 2023

(1) Background: Intraoperative hypotension is common and is associated with increased morbidity and mortality. The Hypotension Prediction Index (HPI) is an advancement of arterial waveform analysis and allows preventive treatments. We used a propensi...

  • Review
  • Open Access
13 Citations
5,694 Views
18 Pages

28 November 2022

Municipal solid waste treatment and disposal have become one of the major concerns in waste management due to the excessive production of waste and higher levels of pollution. To address these challenges and protect the environment in sustainable way...

  • Article
  • Open Access
1 Citations
7,016 Views
22 Pages

Urban Vulnerability Assessment of Sea Level Rise in Singapore through the World Avatar

  • Shin Zert Phua,
  • Kok Foong Lee,
  • Yi-Kai Tsai,
  • Srishti Ganguly,
  • Jingya Yan,
  • Sebastian Mosbach,
  • Trina Ng,
  • Aurel Moise,
  • Benjamin P. Horton and
  • Markus Kraft

3 September 2024

This paper explores the application of The World Avatar (TWA) dynamic knowledge graph to connect isolated data and assess the impact of rising sea levels in Singapore. Current sea level rise vulnerability assessment tools are often regional, narrow i...

  • Article
  • Open Access
1,350 Views
15 Pages

Myocardial Injury and Postoperative Hypotension in the Recovery Room Are Not Correlated: A Retrospective Cohort Study

  • Thijmen J. J. de Ruiter,
  • Robert Jan Stolker,
  • Sanne E. Hoeks and
  • Felix van Lier

7 October 2025

Background: Hypotension is common during and after surgery and is known to be associated with myocardial injury. This study investigated whether hypotension in the recovery room after non-cardiac surgery is associated with myocardial injury. Methods:...

  • Article
  • Open Access
15 Citations
5,618 Views
14 Pages

Optimization of Time-Weighted Average Air Sampling by Solid-Phase Microextraction Fibers Using Finite Element Analysis Software

  • Bulat Kenessov,
  • Jacek A. Koziel,
  • Nassiba Baimatova,
  • Olga P. Demyanenko and
  • Miras Derbissalin

23 October 2018

Determination of time-weighted average (TWA) concentrations of volatile organic compounds (VOCs) in air using solid-phase microextraction (SPME) is advantageous over other sampling techniques, but is often characterized by insufficient accuracies, pa...

  • Article
  • Open Access
2 Citations
3,553 Views
19 Pages

Semi-Classical Discretization and Long-Time Evolution of Variable Spin Systems

  • Giovani E. Morales-Hernández,
  • Juan C. Castellanos,
  • José L. Romero and
  • Andrei B. Klimov

28 May 2021

We apply the semi-classical limit of the generalized SO(3) map for representation of variable-spin systems in a four-dimensional symplectic manifold and approximate their evolution terms of effective classical dynamics on T*S2. Using the asymptotic f...

  • Feature Paper
  • Article
  • Open Access
26 Citations
5,449 Views
21 Pages

21 August 2018

We construct a class of variational methods for the study of open quantum systems based on Gaussian ansatzes for the quantum trajectory formalism. Gaussianity in the conjugate position and momentum quadratures is distinguished from Gaussianity in den...

  • Article
  • Open Access
3 Citations
3,298 Views
20 Pages

11 July 2024

A transcriptome-wide association study (TWAS) was conducted on genome-wide association study (GWAS) summary statistics of malignant melanoma of skin (UK Biobank dataset) and The Cancer Genome Atlas-Skin Cutaneous Melanoma (TCGA-SKCM) gene expression...

  • Article
  • Open Access
36 Citations
4,499 Views
13 Pages

Background: There are few published studies concerning occupational exposure to glyphosate (GLY), and these are limited to spraying, horticulture and other agricultural aspects. Therefore, the concentration of glyphosate and its metabolite aminomethy...

  • Feature Paper
  • Article
  • Open Access
1 Citations
1,917 Views
15 Pages

6 February 2024

This study aimed to investigate the effect of combined Free Nitrous Acid (FNA)-Heat (i.e., FNH) pretreatment on single- and two-stage anaerobic digestion (AD) of thickened waste-activated sludge (TWAS). Single-stage AD was conducted in batches, while...

  • Article
  • Open Access
9 Citations
5,171 Views
9 Pages

Agreement between the Open Barbell and Tendo Linear Position Transducers for Monitoring Barbell Velocity during Resistance Exercise

  • Adam M. Gonzalez,
  • Gerald T. Mangine,
  • Robert W. Spitz,
  • Jamie J. Ghigiarelli and
  • Katie M. Sell

23 May 2019

To determine the agreement between the Open Barbell (OB) and Tendo weightlifting analyzer (TWA) for measuring barbell velocity, eleven men (19.4 ± 1.0 y) performed one set of 2–3 repetitions at four sub-maximal percentage loads, [i.e., 3...

  • Article
  • Open Access
1 Citations
3,957 Views
27 Pages

2 November 2023

The aim of this article is to investigate two external flexible forms of employment—the leasing of workers through Temporary Work Agencies (TWAs) and the contracted workers employed through Business Service Providers (contractors). Undoubtedly,...

  • Article
  • Open Access
9 Citations
2,737 Views
12 Pages

15 April 2024

Anaerobic co-digestion (AnCoD) presents several advantages over conventional mono-digestion. Various factors can impact the efficiency of the co-digestion process, including the mixing ratio of the feedstocks. This study primarily investigates the ef...

  • Review
  • Open Access
11 Citations
4,713 Views
14 Pages

7 September 2018

The isolated terawatt (TW) attosecond (as) hard X-ray pulse will expand the scope of ultrafast science, including the examination of phenomena that have not been studied before, such as the dynamics of electron clouds in atoms, single-molecule imagin...

  • Article
  • Open Access
3 Citations
4,870 Views
12 Pages

Meta-Analysis of Transcriptome-Wide Association Studies across 13 Brain Tissues Identified Novel Clusters of Genes Associated with Nicotine Addiction

  • Zhenyao Ye,
  • Chen Mo,
  • Hongjie Ke,
  • Qi Yan,
  • Chixiang Chen,
  • Peter Kochunov,
  • L. Elliot Hong,
  • Braxton D. Mitchell,
  • Shuo Chen and
  • Tianzhou Ma

23 December 2021

Genome-wide association studies (GWAS) have identified and reproduced thousands of diseases associated loci, but many of them are not directly interpretable due to the strong linkage disequilibrium among variants. Transcriptome-wide association studi...

  • Case Report
  • Open Access
2,152 Views
11 Pages

Noninvasive Ambulatory Electrocardiographic Markers from Patients with COVID-19 Pneumonia: A Report of Three Cases

  • Motohiro Kimata,
  • Kenichi Hashimoto,
  • Naomi Harada,
  • Yusuke Kawamura,
  • Yoshifumi Kimizuka,
  • Yuji Fujikura,
  • Mayuko Kaneko,
  • Nobuaki Kiriu,
  • Yasumasa Sekine and
  • Yuji Tanaka
  • + 4 authors

19 April 2024

Coronavirus disease 2019 (COVID-19) has affected medical practice. More than 7,000,000 patients died worldwide after being infected with COVID-19; however, no specific laboratory markers have yet been established to predict death related to this dise...

  • Article
  • Open Access
1 Citations
1,171 Views
8 Pages

Detection and evaluation of ventricular repolarization alternans: An approach to combined ECG, thoracic impedance, and beat-to-beat heart rate variability analysis

  • Algimantas Kriščiukaitis,
  • Renata Šimoliūnienė,
  • Andrius Macas,
  • Robertas Petrolis,
  • Kęstutis Drėgūnas,
  • Giedrė Bakšytė,
  • Linas Pieteris,
  • Zita Bertašienė and
  • Remigijus Žaliūnas

27 November 2014

Background and objective: Beat-to-beat alteration in ventricles repolarization reflected by alternans of amplitude and/or shape of ECG S-T,T segment (TWA) is known as phenomena related with risk of severe arrhythmias leading to sudden cardiac death....

  • Article
  • Open Access
3 Citations
1,710 Views
18 Pages

Preserving ancient buildings can be improved using Building Information Modelling (BIM) models created from high-quality point-cloud data. The problems arise from the need for automatic extraction of the characteristics required to meet various secur...

  • Article
  • Open Access
1 Citations
2,127 Views
23 Pages

Water Use, Growth, and Yield of Ratooned Guayule under Subsurface Drip and Furrow Irrigation in the US Southwest Desert

  • Diaa Eldin M. Elshikha,
  • Peter M. Waller,
  • Douglas J. Hunsaker,
  • Kelly R. Thorp,
  • Guangyao (Sam) Wang,
  • David Dierig,
  • Von Mark V. Cruz,
  • Said Attalah,
  • Matthew E. Katterman and
  • Kimberly L. Ogden
  • + 5 authors

28 September 2023

Guayule (Parthenium argentatum, A. Gray) is a perennial desert shrub with ratoon-cropping potential for multiple harvests of its natural rubber, resin, and bagasse byproducts. However, yield expectations, water use requirements, and irrigation schedu...

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