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Keywords = quality control circle

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35 pages, 14791 KB  
Article
Optimal Voltage Control for Remote Marine Loads via Subsea Cables: A Solution Circle-Based Comparative Efficiency Analysis of UPFC, SSSC, and TCSC
by Izabel Nikolaeva, Nikolay Nikolaev, Ara Panosyan and Jens Denecke
Energies 2026, 19(7), 1638; https://doi.org/10.3390/en19071638 - 26 Mar 2026
Viewed by 356
Abstract
Maintaining voltage stability and minimizing power losses for remote marine loads powered by long submarine cables is the challenging context of this paper. Flexible Alternating Current Transmission Systems (FACTS) are well-studied for terrestrial grids. However, their comparative performance and efficiency in the context [...] Read more.
Maintaining voltage stability and minimizing power losses for remote marine loads powered by long submarine cables is the challenging context of this paper. Flexible Alternating Current Transmission Systems (FACTS) are well-studied for terrestrial grids. However, their comparative performance and efficiency in the context of high-capacity submarine links remain a gap in the literature. This paper presents a rigorous analysis of the performance of a Unified Power Flow Controller (UPFC), Static Synchronous Series Compensator (SSSC), and Thyristor Controlled Series Capacitor (TCSC). A mathematical framework is developed to introduce the “solution circle” concept, which demonstrates that the series impedance values required to maintain a specific load voltage define a circle in the complex plane. A theoretical analysis is performed, revealing that the UPFC, with its two degrees of freedom, is significantly more efficient because it can select the minimum impedance magnitude on this circle. In contrast, SSSC and TCSC are limited to the reactive axis, which, under certain operating conditions, may not cross the solution circle; therefore, they may not meet the power quality objective. The results of a practical case study show that UPFC requires approximately half the rated power (22.4 MVA) compared to its counterparts (39.4 MVA) to achieve the same control objectives. Full article
(This article belongs to the Section F1: Electrical Power System)
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17 pages, 1025 KB  
Article
CLM App: Interlamellar Distance of Pearlite via CLM Revisited and Automated
by Martin Zouhar, Šárka Mikmeková, Jan Hovjacký and Petra Váňová
Materials 2026, 19(3), 635; https://doi.org/10.3390/ma19030635 - 6 Feb 2026
Viewed by 338
Abstract
Pearlitic (stainless) steel is used in automotive, aerospace, and other industries where high strength, hardness, and wear resistance are required. Its quality control can be performed using mechanical tests or by examining the lamellar microstructure, namely, determining interlamellar distance. One of the related [...] Read more.
Pearlitic (stainless) steel is used in automotive, aerospace, and other industries where high strength, hardness, and wear resistance are required. Its quality control can be performed using mechanical tests or by examining the lamellar microstructure, namely, determining interlamellar distance. One of the related approaches is the circular line method (CLM). This paper reviews the challenges to automate employment of the CLM using custom Python code in order to reduce human time costs during image-based quality assessment of pearlite. The goal is to perform intersection counting automatically once the human operator has configured the application and selected the locations of measuring circles. Performance assessment using manually processed data from some 465 images is performed. We divide the imaged pearlite microstructures into different “types” when the code performs well or, respectively, not so well. We conclude with possible extensions of the work presented here. Full article
(This article belongs to the Section Metals and Alloys)
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15 pages, 1075 KB  
Review
From Pain Catastrophizing to Hopelessness: Neurobiological Mechanisms, Causes, and Evidence-Based Implications for Pain and Outcomes in Rheumatic Diseases
by Ellen Frances O’Carroll, Annalisa Marino and Stefano Di Donato
Rheumato 2026, 6(1), 3; https://doi.org/10.3390/rheumato6010003 - 7 Jan 2026
Viewed by 1442
Abstract
Pain catastrophizing (PC) and hopelessness are increasingly recognized as central determinants of pain severity, disability, and treatment response in individuals with rheumatic and immune-mediated diseases. Traditionally conceptualized as secondary emotional reactions to pain, these cognitive-affective constructs instead represent active mechanisms that shape symptom [...] Read more.
Pain catastrophizing (PC) and hopelessness are increasingly recognized as central determinants of pain severity, disability, and treatment response in individuals with rheumatic and immune-mediated diseases. Traditionally conceptualized as secondary emotional reactions to pain, these cognitive-affective constructs instead represent active mechanisms that shape symptom perception, behavioral responses, and long-term outcomes. In this review, we synthesize evidence across neurobiological, psychological, and clinical domains to elucidate the pathways linking PC and hopelessness to maladaptive coping, kinesiophobia, and functional decline. Early life stress, trauma, and maladaptive cognitive schemas emerge as upstream vulnerability factors that prime heightened emotional reactivity and reduced prefrontal regulatory control, facilitating amplified pain signaling and fear-based avoidance behaviors. Avoidance and inactivity foster physical deconditioning, fatigue, and higher perceived disability, creating a vicious circle that sustains distress and poor quality of life. Moreover, inactivity-related metabolic dysfunction and weight gain may contribute to low-grade inflammation, particularly in conditions such as psoriatic arthritis, thereby intersecting with biological disease pathways. Importantly, these psychological processes identify a distinct patient subgroup for whom further escalation of immunosuppressive therapy provides limited benefit. Instead, integrated psychological approaches—including cognitive behavioral therapy, acceptance and commitment therapy, and coping-skills training—demonstrate meaningful effects on catastrophizing, agency, and functional recovery. We emphasize the need for routine screening to detect patients with maladaptive cognitive–emotional profiles and propose a stratified care model prioritizing targeted psychological interventions alongside standard rheumatologic therapy. Future research should refine phenotyping strategies, clarify neuroimmune links, and develop scalable intervention models to break the avoidance cycle and improve patient-centered outcomes. Full article
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14 pages, 510 KB  
Article
The Impact of Precisely Controlled Pre-Freeze Cooling Rates on Post-Thaw Stallion Sperm
by Aviv Bitton, Amos Frishling, Dorit Kalo, Zvi Roth and Amir Arav
Animals 2026, 16(1), 21; https://doi.org/10.3390/ani16010021 - 21 Dec 2025
Viewed by 679
Abstract
Cryopreservation is a key tool in assisted reproduction, but it often compromises post-thaw sperm quality due to cryodamage. Optimizing the initial cooling phase, specifically from room temperature to 5 °C, is a critical determinant of successful outcomes. This study aimed to evaluate the [...] Read more.
Cryopreservation is a key tool in assisted reproduction, but it often compromises post-thaw sperm quality due to cryodamage. Optimizing the initial cooling phase, specifically from room temperature to 5 °C, is a critical determinant of successful outcomes. This study aimed to evaluate the impact of different pre-freeze cooling rates on stallion sperm quality using a novel, precision cooling device. Semen samples from five healthy stallions were divided into three groups and cooled at distinct rates: Slow (0.3 °C/min), Moderate (1 °C/min), and Fast (approximately 30 °C/min). Sperm motility parameters were assessed using a Computer-Assisted Sperm Analyzer (CASA) before freezing and after thawing. Additionally, sperm integrity and physiological parameters, including viability, acrosomal integrity, Reactive Oxygen Species (ROS) expression, and mitochondrial membrane potential, were assessed by flow cytometry post-thaw. The analysis of post-thaw kinematics revealed a significant interaction between the cooling rate and processing stage (post-cooling vs. post-thaw). The Fast-cooling protocol resulted in higher post-thaw total motility (51.8%) compared to the Slow protocol (45.01%). Crucially, no significant differences were detected among cooling rates for the critical parameter of progressive motility or curvilinear velocity (VCL). Circle motility had higher values in the Fast-cooling group compared to the Slow group. Cell viability demonstrated a tendency (p = 0.08), where the Slow cooling group exhibited higher mean values (65.59%) compared to the Fast group (61.67%). Comprehensive flow cytometry assessments of other cellular integrity markers, including acrosomal integrity, mitochondrial function (MMP), and ROS expression, were statistically equivalent across all cooling rates (p > 0.05). The results confirm that this fast pre-freeze cooling rate, integrated within the highly controlled environment of Directional Freezing technology, successfully preserved essential sperm function and structure. Critically, the demonstrated functional equivalence in progressive motility validates the Fast protocol as an efficacious strategy to increase the efficiency and adaptability of equine semen cryopreservation protocols for commercial utilization. Full article
(This article belongs to the Section Equids)
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26 pages, 1253 KB  
Article
Integrated Production, EWMA Scheme, and Maintenance Policy for Imperfect Manufacturing Systems of Bolt-On Vibroseis Equipment Considering Quality and Inventory Constraints
by Nuan Xia, Zilin Lu, Yuting Zhang and Jundong Fu
Axioms 2025, 14(9), 703; https://doi.org/10.3390/axioms14090703 - 17 Sep 2025
Viewed by 692
Abstract
In recent years, the synergistic effect among production, maintenance, and quality control within manufacturing systems has garnered increasing attention in academic and industrial circles. In high-quality production settings, the real-time identification of minute process deviations holds significant importance for ensuring product quality. Traditional [...] Read more.
In recent years, the synergistic effect among production, maintenance, and quality control within manufacturing systems has garnered increasing attention in academic and industrial circles. In high-quality production settings, the real-time identification of minute process deviations holds significant importance for ensuring product quality. Traditional approaches, such as routine quality inspections or Shewhart control charts, exhibit limitations in sensitivity and response speed, rendering them inadequate for meeting the stringent requirements of high-precision quality control. To address this issue, this paper presents an integrated framework that seamlessly integrates stochastic process modeling, dynamic optimization, and quality monitoring. In the realm of quality monitoring, an exponentially weighted moving average (EWMA) control chart is employed to monitor the production process. The statistic derived from this chart forms a Markov process, enabling it to more acutely detect minor shifts in the process mean. Regarding maintenance strategies, a state-dependent preventive maintenance (PM) and corrective maintenance (CM) mechanism is introduced. Specifically, preventive maintenance is initiated when the system is in a statistically controlled state and the inventory level falls below a predefined threshold. Conversely, corrective maintenance is triggered when the EWMA control chart generates an out-of-control (OOC) signal. To facilitate continuous production during maintenance activities, an inventory buffer mechanism is incorporated into the model. Building upon this foundation, a joint optimization model is formulated, with system states, including equipment degradation state, inventory level, and quality state, serving as decision variables and the minimization of the expected total cost (ETC) per unit time as the objective. This problem is formalized as a constrained dynamic optimization problem and is solved using the genetic algorithm (GA). Finally, through a case study of the production process of vibroseis equipment, the superiority of the proposed model in terms of cost savings and system performance enhancement is empirically verified. Full article
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24 pages, 1469 KB  
Article
Effective Practices for Implementing Quality Control Circles Aligned with ISO Quality Standards: Insights from Employees and Managers in the Food Industry
by Ana Beatriz Silva de Lima, Claudia Editt Tornero Becerra, Amanda Duarte Feitosa, André Philippi Gonzaga de Albuquerque, Fagner José Coutinho de Melo and Denise Dumke de Medeiros
Standards 2025, 5(1), 6; https://doi.org/10.3390/standards5010006 - 27 Feb 2025
Cited by 1 | Viewed by 6836
Abstract
Quality control circles (QCCs) are a proven method for fostering continuous improvement through employee involvement. However, the implementation process and organizational impact of QCCs in the food industry remain underexplored. This case study evaluates the implementation of QCCs by examining the benefits and [...] Read more.
Quality control circles (QCCs) are a proven method for fostering continuous improvement through employee involvement. However, the implementation process and organizational impact of QCCs in the food industry remain underexplored. This case study evaluates the implementation of QCCs by examining the benefits and challenges perceived by employees and managers, assessing QCC alignment with ISO standards, and providing actionable recommendations to optimize QCC implementation. Using a mixed-methods approach, the employee findings indicate that QCCs promote continuous improvement, enhance productivity, foster a positive culture of quality, and strengthen engagement and responsibility for product and process quality. Employees felt that their ideas were valued and that they received constructive feedback from leadership. However, they also identified challenges related to training and resource availability. From a managerial perspective, the ISO diagnostic tool revealed a 78.28% compliance rate with the QCC program planning, quality procedures, action plans, quality management system alignment, and documentation. Non-conformities included insufficient monitoring solutions, absence of effectiveness indicators, lack of risk assessments, and insufficient resources. Although managers acknowledged benefits such as improved engagement and communication, challenges such as limited human resources, high demand, and resistance to change were also noted. This paper concludes with recommendations for enhancing future QCC cycles and for creating a structured implementation process. Full article
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13 pages, 2207 KB  
Article
Inline-Acquired Product Point Clouds for Non-Destructive Testing: A Case Study of a Steel Part Manufacturer
by Michalis Ntoulmperis, Silvia Discepolo, Paolo Castellini, Paolo Catti, Nikolaos Nikolakis, Wilhelm van de Kamp and Kosmas Alexopoulos
Machines 2025, 13(2), 88; https://doi.org/10.3390/machines13020088 - 23 Jan 2025
Cited by 3 | Viewed by 1953
Abstract
Modern vision-based inspection systems are inherently limited by their two-dimensional nature, particularly when inspecting complex product geometries. These systems are often unable to capture critical depth information, leading to challenges in accurately measuring features such as holes, edges, and surfaces with irregular curvature. [...] Read more.
Modern vision-based inspection systems are inherently limited by their two-dimensional nature, particularly when inspecting complex product geometries. These systems are often unable to capture critical depth information, leading to challenges in accurately measuring features such as holes, edges, and surfaces with irregular curvature. To address these shortcomings, this study introduces an approach that leverages computer-aided design-oriented three-dimensional point clouds, captured via a laser line triangulation sensor mounted onto a motorized linear guide. This setup facilitates precise surface scanning, extracting complex geometrical features, which are subsequently processed through an AI-based analytical component. Dimensional properties, such as radii and inter-feature distances, are computed using a combination of K-nearest neighbors and least-squares circle fitting algorithms. This approach is validated in the context of steel part manufacturing, where traditional 2D vision-based systems often struggle due to the material’s reflectivity and complex geometries. This system achieves an average accuracy of 95.78% across three different product types, demonstrating robustness and adaptability to varying geometrical configurations. An uncertainty analysis confirms that the measurement deviations remain within acceptable limits, supporting the system’s potential for improving quality control in industrial environments. Thus, the proposed approach may offer a reliable, non-destructive inline testing solution, with the potential to enhance manufacturing efficiency. Full article
(This article belongs to the Special Issue Application of Sensing Measurement in Machining)
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19 pages, 21153 KB  
Article
AI-Based Integrated Smart Process Sensor for Emulsion Control in Industrial Application
by Inga Burke, Sven Salzer, Sebastian Stein, Tom Olatomiwa Olakunle Olusanya, Ole Fabian Thiel and Norbert Kockmann
Processes 2024, 12(9), 1821; https://doi.org/10.3390/pr12091821 - 27 Aug 2024
Cited by 10 | Viewed by 4018
Abstract
In industry, reliable process supervision is essential to ensure efficient, safe, and high-quality production. The droplet size distribution represents a critical quality attribute for emulsification processes and should be monitored. For emulsion characterization, image-based analysis methods are well-known but are often performed offline, [...] Read more.
In industry, reliable process supervision is essential to ensure efficient, safe, and high-quality production. The droplet size distribution represents a critical quality attribute for emulsification processes and should be monitored. For emulsion characterization, image-based analysis methods are well-known but are often performed offline, leading to a time-delayed and error-prone process evaluation. The use of an integrated smart process sensor to characterize the emulsification process over time enables the real-time evaluation of the entire system. The presented integrated smart process sensor consists of an optical measurement flow cell built into a camera system. The overall system is placed in a bypass system of a production plant for emulsification processes. AI-based image evaluation is used in combination with a feature extraction method (You Only Look Once version 4 (YOLOv4) and Hough circle (HC)) to characterize the process over time. The sensor system is installed in the plant and tested with different cosmetic products. Various iteration, prototyping, and test steps for the final sensor design are performed prior to this in a laboratory test setup. The results indicate robust and accurate detection and determination of the droplet size in real time to improve product control and save time. For benchmarking the integrated smart process sensor, the results are compared with common analysis methods using offline samples. Full article
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17 pages, 13714 KB  
Article
The Influence of Insertion Depth of Inorganic Materials on Solidification Microstructure and Segregation of 2.5-ton 42CrMo Ingot
by Shujian Sun, Yonglong Du, Zhenqiang Zhang, Danqing Jiang, Songzhe Xu and Zhongming Ren
Metals 2024, 14(7), 753; https://doi.org/10.3390/met14070753 - 25 Jun 2024
Cited by 2 | Viewed by 1812
Abstract
In this work, a novel internal heat absorption technology using inorganic material rods is employed during the solidification process of steel ingots, aiming to control their solidification and improve the quality of the final product. The study investigates the effect of the insertion [...] Read more.
In this work, a novel internal heat absorption technology using inorganic material rods is employed during the solidification process of steel ingots, aiming to control their solidification and improve the quality of the final product. The study investigates the effect of the insertion depth of inorganic materials on the solidification microstructure and macrosegregation of 2.5-ton 42CrMo ingots. The mechanical properties of samples from the product are also tested. A numerical simulation model for casting 2.5-ton ingots is established and implemented in Ansys Fluent fluid simulation software, with inorganic material rods set at different preset depths. The simulation explores the physical processes of the melting and floating of inorganic materials in molten steel, as well as their effects on the temperature and flow fields of the material. The results show that deeper insertion of inorganic materials (200 mm from the hot top) reduces the tendency for macrosegregation compared to that at the insertion depth of 100 mm. Specifically, the positive segregation area decreases by 10.35%, while the negative segregation area decreases by 15.32%. Moreover, deeper insertion results in a significant refinement of the solidification microstructure, ultimately enhancing the mechanical properties of the products machined from the ingots (i.e., the yield strength increased by 4.7%). The numerical simulation results indicate that as the placement depth of inorganic materials in the ingot mold increases, the cooling effect becomes more significant, the flow area of molten steel initiated by the inorganic materials expands, and the linear velocity of the double-circle flow increases. This further explains why the solidification quality of the ingots improves with the increasing placement depth of inorganic materials. Full article
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23 pages, 21780 KB  
Article
CLensRimVision: A Novel Computer Vision Algorithm for Detecting Rim Defects in Contact Lenses
by Pawat Chunhachatrachai and Chyi-Yeu Lin
Sensors 2023, 23(23), 9610; https://doi.org/10.3390/s23239610 - 4 Dec 2023
Cited by 8 | Viewed by 4051
Abstract
Automated optical inspection (AOI) plays a pivotal role in the quality control of contact lenses, safeguarding the safety and integrity of lenses intended for both medical and cosmetic applications. As the role of computer vision in defect detection expands, our study probes its [...] Read more.
Automated optical inspection (AOI) plays a pivotal role in the quality control of contact lenses, safeguarding the safety and integrity of lenses intended for both medical and cosmetic applications. As the role of computer vision in defect detection expands, our study probes its effectiveness relative to traditional methods, particularly concerning subtle and irregular defects on the lens rim. In this research study, we propose a novel algorithm designed for the precise and automated detection of rim defects in contact lenses called “CLensRimVision”. This algorithm integrates a series of procedures, including image preprocessing, circle detection for identifying lens rims, polar coordinate transformation, setting defect criteria and their subsequent detection, and, finally, visualization. The method based on these criteria can be adapted either to thickness-based or area-based approaches, suiting various characteristics of the contact lens. This approach achieves an exemplary performance with a 0.937 AP score. Our results offer a richer understanding of defect detection strategies, guiding manufacturers and researchers towards optimal techniques for ensuring quality in the contact lens domain. Full article
(This article belongs to the Special Issue Sensing and Imaging for Defect Detection)
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19 pages, 3211 KB  
Article
Phototactic Behavioral Responses of Mesozooplankton in the Barents Sea as an Indicator of Anthropogenic Impact
by Victor Dyomin, Yuri Morgalev, Sergey Morgalev, Alexandra Davydova, Oksana Kondratova, Tamara Morgaleva and Igor Polovtsev
Water 2023, 15(22), 3901; https://doi.org/10.3390/w15223901 - 8 Nov 2023
Cited by 3 | Viewed by 2129
Abstract
The behavioral responses of autochthonous organisms have recently been used for a system to monitor the state of fresh and sea waters for bioindication. The advantage of using the behavioral responses of mesozooplankton is determined by the higher sensitivity of such responses compared [...] Read more.
The behavioral responses of autochthonous organisms have recently been used for a system to monitor the state of fresh and sea waters for bioindication. The advantage of using the behavioral responses of mesozooplankton is determined by the higher sensitivity of such responses compared with changes in the composition of biota or the death of organisms. Earlier, we developed and tested in laboratory conditions and in freshwater reservoirs a submersible digital holographic camera as part of a hydrobiological probe, which allows one to determine the dimensions, shape and recognition of plankters in situ, as well as define the concentration of plankters in the working volume and perform photostimulation with attractive radiation with different levels of illuminance. This paper presents the data obtained during the expedition to the Barents Sea. The variability with regard to the immersion depth of the phototropic response and the interspecific and intraspecific diversity was determined. It was shown that within the framework of natural variability in natural factors (temperature, salinity, hydrostatic pressure, oxygen content, illumination) there are no reliable changes in the indicator response, unlike changes in the concentration of plankton associated with tidal currents. The anthropogenic distortion of water quality was modeled by introducing a saturated salt solution dropwise. There were no significant changes in the intraspecific and interspecific diversity index during the external impact, and the rhythms of tidal changes in the concentration of plankters were suppressed. The fact of increased phototropic sensitivity in crustaceans with a size of less than 120 μm was found. It was established that the most essential marker of the alternating factor was the suppression of the phototropic response. The identified patterns of behavioral responses of autochthonous zooplankton make it possible to create a network of continuous control over the environmental health of water bodies subject to increased anthropogenic impact (oil production zones beyond the Arctic Circle, estuaries and deltas of rivers carrying industrial waste). Full article
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22 pages, 1373 KB  
Review
Current Approaches in the Multimodal Management of Asthma in Adolescents—From Pharmacology to Personalized Therapy
by Vasile Valeriu Lupu, Elena Jechel, Silvia Fotea, Ionela Daniela Morariu, Iuliana Magdalena Starcea, Alice Azoicai, Adriana Mocanu, Elena Cristina Mitrofan, Ancuta Lupu, Dragos Munteanu, Minerva Codruta Badescu, Magdalena Cuciureanu and Ileana Ioniuc
Biomedicines 2023, 11(9), 2429; https://doi.org/10.3390/biomedicines11092429 - 30 Aug 2023
Cited by 4 | Viewed by 3467
Abstract
Asthma and adolescence are two sensitive points and are difficult to manage when they coexist. The first is a chronic respiratory condition, with frequent onset in early childhood (between 3 and 5 years), which can improve or worsen with age. Adolescence is the [...] Read more.
Asthma and adolescence are two sensitive points and are difficult to manage when they coexist. The first is a chronic respiratory condition, with frequent onset in early childhood (between 3 and 5 years), which can improve or worsen with age. Adolescence is the period between childhood and adulthood (12–19 years), marked by various internal and external conflicts and a limited capacity to understand and accept any aspect that is delimited by the pattern of the social circle (of the entourage) frequented by the individual. Therefore, the clinician is faced with multiple attempts regarding the management of asthma encountered during the adolescent period, starting from the individualization of the therapy to the control of compliance (which depends equally on the adverse reactions, quality of life offered and support of the close circle) and the social integration of the subject, communication probably having a more important role in the monitoring and evolution of the condition than the preference for a certain therapeutic scheme. Current statistics draw attention to the increase in morbidity and mortality among children with bronchial asthma, an aspect demonstrated by the numerous hospitalizations recorded, due either to an escalation in the severity of this pathology or to faulty management. The purpose of this article is to review the delicate aspects in terms of controlling symptoms and maintaining a high quality of life among teenagers. Full article
(This article belongs to the Special Issue Emerging Issues in Asthma)
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32 pages, 5244 KB  
Review
Review of Bioplastics Characterisation by Terahertz Techniques in the View of Ensuring a Circular Economy
by Andreja Abina, Tjaša Korošec, Uroš Puc and Aleksander Zidanšek
Photonics 2023, 10(8), 883; https://doi.org/10.3390/photonics10080883 - 29 Jul 2023
Cited by 8 | Viewed by 4539
Abstract
The increasing scarcity of natural resources, worsening global climate change, environmental degradation, and rising demand for food are forcing the biotechnology and plastics industries to seek and apply circular economy models that would lead to a sustainable transition in the production and use [...] Read more.
The increasing scarcity of natural resources, worsening global climate change, environmental degradation, and rising demand for food are forcing the biotechnology and plastics industries to seek and apply circular economy models that would lead to a sustainable transition in the production and use of bioplastics. Circular economy models can improve the economic productivity of bio-based plastics and have a positive impact on the environment by reducing conventional plastic waste and the consumption of petrochemical feedstocks for plastic production. In addition, some agricultural wastes that have the potential to be used as bioplastics can be reused. Terahertz (THz) systems are already used in the plastics and rubber industries for non-destructive testing, detection, imaging, and quality control. Several reports have highlighted the potential applications of THz spectroscopy and imaging in polymer analysis and plastics characterisation. This potential is even greater with chemometric methods and artificial intelligence algorithms. In this review, we focus on applications that support the transformation of the biotechnology sector to the circular economy, particularly via the transition from conventional plastics to bioplastics. In this review, we discuss the potential of THz systems for the characterisation and analysis of bioplastics and biopolymers. The results of previous studies on biopolymers in the THz frequency range are summarised. Furthermore, the potential of using artificial intelligence approaches such as machine learning as advanced analytical methods in THz spectroscopy and imaging, in addition to the conventionally used chemometric methods, is discussed. The results of this review highlight that THz technology can contribute to closed technological circles in important areas of biotechnology and the related plastics and rubber industries. Full article
(This article belongs to the Special Issue Terahertz Spectroscopy and Imaging)
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15 pages, 4740 KB  
Article
Investigation of the Impact of Hydrogen Bonding Degree in Long Single-Stranded DNA (ssDNA) Generated with Dual Rolling Circle Amplification (RCA) on the Preparation and Performance of DNA Hydrogels
by Xinyu Wang, Huiyuan Wang, Hongmin Zhang, Tianxi Yang, Bin Zhao and Juan Yan
Biosensors 2023, 13(7), 755; https://doi.org/10.3390/bios13070755 - 23 Jul 2023
Cited by 10 | Viewed by 3414
Abstract
DNA hydrogels have gained significant attention in recent years as one of the most promising functional polymer materials. To broaden their applications, it is critical to develop efficient methods for the preparation of bulk-scale DNA hydrogels with adjustable mechanical properties. Herein, we introduce [...] Read more.
DNA hydrogels have gained significant attention in recent years as one of the most promising functional polymer materials. To broaden their applications, it is critical to develop efficient methods for the preparation of bulk-scale DNA hydrogels with adjustable mechanical properties. Herein, we introduce a straightforward and efficient molecular design approach to producing physically pure DNA hydrogel and controlling its mechanical properties by adjusting the degree of hydrogen bonding in ultralong single-stranded DNA (ssDNA) precursors, which were generated using a dual rolling circle amplification (RCA)-based strategy. The effect of hydrogen bonding degree on the performance of DNA hydrogels was thoroughly investigated by analyzing the preparation process, morphology, rheology, microstructure, and entrapment efficiency of the hydrogels for Au nanoparticles (AuNPs)–BSA. Our results demonstrate that DNA hydrogels can be formed at 25 °C with simple vortex mixing in less than 10 s. The experimental results also indicate that a higher degree of hydrogen bonding in the precursor DNA resulted in stronger internal interaction forces, a more complex internal network of the hydrogel, a denser hydrogel, improved mechanical properties, and enhanced entrapment efficiency. This study intuitively demonstrates the effect of hydrogen bonding on the preparation and properties of DNA hydrogels. The method and results presented in this study are of great significance for improving the synthesis efficiency and economy of DNA hydrogels, enhancing and adjusting the overall quality and performance of the hydrogel, and expanding the application field of DNA hydrogels. Full article
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19 pages, 7259 KB  
Article
Optical Imaging Deformation Inspection and Quality Level Determination of Multifocal Glasses
by Hong-Dar Lin, Tung-Hsin Lee, Chou-Hsien Lin and Hsin-Chieh Wu
Sensors 2023, 23(9), 4497; https://doi.org/10.3390/s23094497 - 5 May 2023
Cited by 3 | Viewed by 2878
Abstract
Multifocal glasses are a new type of lens that can fit both nearsighted and farsighted vision on the same lens. This property allows the glass to have various curvatures in distinct regions within the glass during the grinding process. However, when the curvature [...] Read more.
Multifocal glasses are a new type of lens that can fit both nearsighted and farsighted vision on the same lens. This property allows the glass to have various curvatures in distinct regions within the glass during the grinding process. However, when the curvature varies irregularly, the glass is prone to optical deformation during imaging. Most of the previous studies on imaging deformation focus on the deformation correction of optical lenses. Consequently, this research uses an automatic deformation defect detection system for multifocal glasses to replace professional assessors. To quantify the grade of deformation of curved multifocal glasses, we first digitally imaged a pattern of concentric circles through a test glass to generate an imaged image of the glass. Second, we preprocess the image to enhance the clarity of the concentric circles’ appearance. A centroid-radius model is used to represent the form variation properties of every circle in the processed image. Third, the deviation of the centroid radius for detecting deformation defects is found by a slight deviation control scheme, and we gain a difference image indicating the detected deformed regions after comparing it with the norm pattern. Fourth, based on the deformation measure and occurrence location of multifocal glasses, we build fuzzy membership functions and inference regulations to quantify the deformation’s severity. Finally, a mixed model incorporating a network-based fuzzy inference and a genetic algorithm is applied to determine a quality grade for the deformation severity of detected defects. Testing outcomes show that the proposed methods attain a 94% accuracy rate of the quality levels for deformation severity, an 81% recall rate of deformation defects, and an 11% false positive rate for multifocal glass detection. This research contributes solutions to the problems of imaging deformation inspection and provides computer-aided systems for determining quality levels that meet the demands of inspection and quality control. Full article
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