Search Results (104)

This paper presents a microstrip active quasi-circulator designed for low-power wireless communication systems. The circuit consists of a second-order Wilkinson power divider and two power amplifiers with high gain and ultra-low noise characteristics. By leveraging the unidirectional transmission characteristics of the transistors and the isolation provided by resistors within the power divider, the interference between the transmitter (TX) and receiver (RX) is effectively suppressed. Additionally, thanks to the dual-amplifier architecture, no extra power amplification circuitry is required, thereby reducing the overall complexity and power consumption of the communication system. The detailed design procedure of the proposed quasi-circulator is presented. The measurement results show that, within the frequency range of 4.75 GHz to 6.11 GHz, the isolation between the TX and RX ports exceeds 20 dB, the return loss at each port is greater than 10 dB, and the transmission gains from the TX port to the antenna and from the antenna to the RX port are 3.1–8.7 dB and 2.7–4.0 dB, respectively, demonstrating a relative bandwidth of 25%. Full article

This paper presents the results of preliminary numerical and experimental studies concerning the sealing performance of static seals (gaskets) with geometrically designed sealing surface microstructures. The concept of the microstructure, inspired by the operating principle of Tesla’s one-way valve, relies on the generation of localized flow circulation within the microchannels formed between the contact surfaces, which increases flow resistance and reduces leakage. CFD simulations were performed to assess the influence of the geometric parameters of the microstructure on the leakage rate. The numerical calculations demonstrated that introducing microstructures into the gap formed between the contact interfaces can significantly reduce leakage, with the most critical geometric parameters being the gap width between the microprotrusions, their packing density, and their height. Experimental studies confirmed the higher sealing performance of structured gaskets compared to quasi-smooth gaskets, particularly at lower contact pressures. An analysis of the effective contact surface revealed that the improvement in tightness is a result of both the local intensification of the contact pressure and the flow effects induced by the microprotrusions. The results obtained confirm that an appropriately designed surface microstructure can substantially enhance the sealing performance of flange-bolted joints, even under relatively low clamping loads. Full article

This paper presents a comprehensive dynamical analysis of a nonlinear oscillator subjected to both deterministic and stochastic excitations. Utilizing a diverse suite of analytical tools—including phase portraits, Poincaré sections, Lyapunov exponents, recurrence plots, Fokker–Planck equations, and sensitivity diagnostics—we investigate the transitions between quasi-periodicity, chaos, and stochastic disorder. The study reveals that quasi-periodic attractors exhibit robust topological structure under moderate noise but progressively disintegrate as stochastic intensity increases, leading to high-dimensional chaotic-like behavior. Recurrence quantification and Lyapunov spectra validate the transition from coherent dynamics to noise-dominated regimes. Poincaré maps and sensitivity analysis expose multistability and intricate basin geometries, while the Fokker–Planck formalism uncovers non-equilibrium steady states characterized by circulating probability currents. Together, these results provide a unified framework for understanding the geometry, statistics, and stability of noisy nonlinear systems. The findings have broad implications for systems ranging from mechanical oscillators to biological rhythms and offer a roadmap for future investigations into fractional dynamics, topological analysis, and data-driven modeling. Full article

Scramjet operation requires a comprehensive understanding of the internal flowfield, encompassing fuel–air mixing and combustion. This study investigates transient flow and flame development within a HIFiRE-2 scramjet engine combustor, which features two opposing cavities and dual sets of fuel injectors—the upstream (primary) and downstream (secondary) injectors. These cavities function as flameholders, creating circulating flows with elevated temperatures and pressures. Shock waves form both ahead of fuel plumes and at the diverging and converging sections of the flowpath. Special attention is given to the interactions among these shock waves and the shear layers along the supersonic core flow as the system progresses towards a quasi-steady state. Driven by increased backpressure, bow shocks and disturbances induced by the normal, secondary fuel injection and the inclined, primary fuel injection move upstream, amplifying the cavity pressure. These shocks generate adverse pressure gradients, causing near-wall flow separation adjacent to both injector sets, which enhances the penetration and dispersion of fuel plumes. Once a quasi-steady state is achieved, a feedback loop is established between dynamic wave motions and combustion processes, resulting in sustained entrainment of reactive mixtures into the cavities. This mechanism facilitates stable combustion in the cavities and near-wall separation zones. Full article

Background/Objectives: Romania remains a tuberculosis (TB) hotspot in the European Union, yet host-derived factors of poor outcomes are poorly characterised. We quantified circulating pro-inflammatory cytokines and examined their interplay with behavioural risk factors, the nutritional status, and the clinical course in adults hospitalised with pulmonary TB. We analysed 80 adults with microbiologically confirmed pulmonary TB and 40 respiratory symptom controls; four TB patients (5%) died during hospitalisation, all within 10 days of admission. Methods: A retrospective analytical case–control study was conducted at the Constanța regional TB referral centre (October 2020—October 2023). Patients with smear- or culture-confirmed TB were frequency-matched by sex, 10-year age band, and BMI class to culture-negative respiratory controls at a 2:1 ratio. The patients’ serum interferon-γ (IFN-γ), interleukin-1α (IL-1α), interleukin-1β (IL-1β), and tumour-necrosis-factor-α (TNF-α) were quantified within 24 h of admission; the neutrophil/lymphocyte ratio (NLR) was extracted from full blood counts. Independent predictors of in-hospital mortality were identified by multivariable logistic regression; factors associated with the length of stay (LOS) were modelled with quasi-Poisson regression. Results: The median TNF-α (24.1 pg mL⁻¹ vs. 16.2 pg mL⁻¹; p = 0.009) and IL-1β (5.34 pg mL⁻¹ vs. 3.67 pg mL⁻¹; p = 0.008) were significantly higher in the TB cases than in controls. TNF-α was strongly correlated with IL-1β (ρ = 0.80; p < 0.001), while NLR showed weak concordance with multiplex cytokine patterns. Among the patients with TB, four early deaths (5%) exhibited a tripling of TNF-α (71.4 pg mL⁻¹) and a doubling of NLR (7.8) compared with the survivors. Each 10 pg mL⁻¹ rise in TNF-α independently increased the odds of in-hospital death by 1.8-fold (95% CI 1.1–3.0; p = 0.02). The LOS (median 29 days) was unrelated to the smoking, alcohol, or comorbidity load, but varied across BMI strata: underweight, 27 days; normal weight, 30 days; overweight, 23 days (Kruskal–Wallis p = 0.03). In a multivariable analysis, under-nutrition (BMI < 18.5 kg m⁻²) prolonged the LOS by 19% (IRR 1.19; 95% CI 1.05–1.34; p = 0.004) independently of the disease severity. Conclusions: A hyper-TNF-α/IL-1β systemic signature correlates with early mortality in Romanian pulmonary TB, while under-nutrition is the dominant modifiable determinant of prolonged hospitalisation. Admission algorithms that pair rapid TNF-α testing with systematic nutritional assessment could enable targeted host-directed therapy trials and optimise bed utilisation in high-burden settings. Full article

Urban heat island circulation (UHIC) determines the wind and thermal environments in urban areas. For Loess Tableland valley towns, the evolution characteristics of the UHIC over this negative terrain are not well understood, and therefore, it is important to investigate the evolution characteristics. A city-scale computational fluid dynamics (CSCFD) model is used, and simulation results are validated by the water tank experiment. The evolution process over such negative terrain can be divided into transient and quasi-steady stages, and in the transient stage, the airflow pattern evolves from thermal convection to city-scale closed circulation, while that in the quasi-steady stage is only city-scale closed circulation. In order to further reveal the characteristics of city-scale closed circulation, the sensitivities of different factors influencing the start time, outflow time, mixing height and heat island intensity are analyzed, and the most significant factors influencing these four parameters are urban heat flux, slope height, slope height, and potential temperature lapse rate, respectively. Finally, the dimensionless mixing height and heat island intensity for the valley town increase by 56.80% and 128.68%, respectively, compared to those for the flat city. This study provides guidance for the location and layout of built-up areas in the valley towns. Full article

Midlatitude westerly and East Asian summer monsoon (EASM) are crucial circulation systems in the upper and lower troposphere of East Asia that significantly influence mid-summer precipitation pattern. However, their synergistic effect on mid-summer precipitation in North China (NC) remains unclear. In this study, the concurrent variations of mid-summer westerly and EASM are categorized into two configurations: strong westerly–strong EASM (SS) and weak westerly–weak EASM (WW). At the synoptic timescale, the SS configuration significantly enhances precipitation in NC, whereas the WW configuration suppresses mid-summer rainfall. The underlying mechanism is that the SS pattern stimulates an anomalous quasi-barotropic cyclone–anticyclone pair over the Mongolian Plateau–Yellow Sea region. Two anomalous water vapor channels (westerly-driven and EASM-driven water vapor transport) are established in the southern and western peripheries of this cyclone–anticyclone pair, ensuring abundant moisture supply over NC. Meanwhile, frequently occurring westerly jet cores in northern NC form a jet entrance region, favoring strong upper-level divergent pumping and deep accents in its southern flank. This synergy between strong westerlies and EASM enhances both the moisture transports and ascending movements, thereby increasing precipitation over NC. Conversely, the atmospheric circulation associated with the WW pattern exhibits opposite characteristics, resulting in decreased NC rainfall. Our findings elucidate the synoptic-scale influences of westerly–monsoon synergy on mid-summer rainfall, through regulating moisture transports and westerly jet-induced dynamic uplift, potentially improving predictive capabilities for mid-summer precipitation forecasting. Full article

In this study, through RH water model simulation experiments, the effects of precipitation bubbles on the two-phase flow pattern, liquid steel flow behavior, and flow characteristics in an RH reactor during the whole decarburization process were comparatively investigated and analyzed by using quasi-counts that reflected the similarity of the precipitation bubble phenomenon. The experimental results show that an increase in precipitation bubbles is positively related to an increase in circulating flow rate, a reduction in mixing time, and an increase in gas content and negatively related to the residence time of liquid steel in the vacuum chamber. The two-phase flow pattern of the rising tube under the influence of precipitation bubbles includes bubble flow, slug flow, mixing flow, and churn flow. Under the influence of precipitation bubbles, the liquid surface spattering inside the vacuum chamber is reduced, the fluctuation amplitude is reduced, the efficiency of liquid steel processing is improved, it is not easy for cold steel to form, and the fluctuation frequency is increased, which is conducive to increasing the surface area of the vacuum chamber; the bubbles’ rising, aggregating, and crushing behavior increases the stirring effect inside the vacuum chamber, which is conducive to improving the decarburization and mass transfer rate. Under the influence of the precipitated bubbles, the concentration gradient between the ladle and the vacuum chamber is increased, which accelerates the mixing speed of the liquid steel in the ladle, and the volume of the dead zone is reduced by 50%. The lifting gas flow rate can be appropriately reduced in the plant. Full article

A severe cold air outbreak hit the US and parts of Canada in January 2019, leaving behind many casualties where at least 21 people died as a consequence. According to Insurance Business America, the event cost the US about 1 billion dollars. In the Midwest, surface temperatures dipped to the lowest on record in decades, reaching −32 °C in Chicago, Illinois, and down to −48 °C wind chill temperature in Cotton and Dakota, Minnesota, giving rise to broad media attention. A zonal wavenumber 1–3 planetary wave forcing caused a sudden stratospheric warming, with a displacement followed by a split of the polar vortex at the beginning of 2019. The common downward progression of the stratospheric anomalies stalled at the tropopause and, thus, they did not reach tropospheric levels. Instead, the stratospheric trough, developing in a barotropic fashion around 70° W, turned the usually baroclinic structure of the Aleutian high quasi-barotropic. In response, upward propagating waves over the North Pacific were reflected at its lower stratospheric, eastward tilting edge toward North America. Channeled by a dipole structure of positive and negative eddy geopotential height anomalies, the waves converged at the center of the latter and thereby strengthened the circulation anomalies responsible for the severely cold surface temperatures in most of the Midwest and Northeast US. Full article

This paper focuses on the development and experimental validation of a single-phase modular multilevel converter (MMC) based on a battery energy storage system (BESS) for residential uninterruptible power supply (UPS) with two-level active SoC balancing control. The configuration and mathematical modeling of the single-phase MMC-BESS are first presented, followed by the details of the control strategies, including dual-loop output voltage and current control in islanded mode, grid-connected control, circulating current control, and two-level active state-of-charge (SoC) balancing control. The design and optimization of the quasi-proportional-resonant (QPR) controllers were investigated by using particle swarm optimization (PSO). Simulation models were built to explore the operating characteristics of the UPS under islanded mode with an RL load and grid-connected mode and assess the control performance. A 500 W experimental prototype was developed and is herein presented, including results under different operating conditions of the MMC-BESS. The experimental results show that for both RL load and grid-connected tests, balancing was achieved. The response time to track the reference value was two grid periods (0.04 s). In the islanded mode test, the THD was 1.37% and 4.59% for the voltage and current, respectively, while in the grid-connected mode test, these values were 1.72% and 4.24% for voltage and current, respectively. Full article

As a key initiative to integrate economic growth and green development in the era of the digital economy, the environmental effects of China’s Cross-border E-commerce Comprehensive Pilot Zone (CBEC-PZ) policy are not yet clear. Based on city-level data from 2014 to 2021 in China and leveraging the CBEC-PZ policy as a quasi-natural experiment, this study reveals that the CBEC-PZ policy has significantly enhanced local air quality, with particularly pronounced effects in eastern regions. While the policy did not degrade air quality in surrounding areas, spatial correlations of air quality levels among regions were observed due to atmospheric circulation dynamics. These findings underscore the importance of emphasizing regional coordination in green development within urban governance frameworks. The CEBC-PZ promotes the transformation of the energy structure and the improvement of air quality through reverse innovation, an ecological competitive advantage, and an agile governance mechanism. It is recommended to help synergize sustainable development and high-quality development in terms of strengthening reverse innovation and institutional innovation, expanding cross-regional synergistic governance, and deepening digital-real integration. Full article

Variations in stratospheric atmospheric circulation significantly impact tropospheric weather and climate. Understanding these variations not only aids in better prediction of tropospheric weather and climate but also provides guidance for the development and flight trajectories of stratospheric aircraft. Our understanding of the stratosphere has made remarkable progress over the past 100 years. However, we still lack a comprehensive perspective on large-scale patterns in stratospheric circulation, as the stratosphere is a typical complex system. To address this gap, we employed the eigen microstate approach (EMA) to revisit the characteristics of zonal wind from 70–10 hPa from 1980 to 2022, based on ERA5 reanalysis data. Our analysis focused on the three leading modes, corresponding to variations in the strength of the quasi-biennial oscillation (QBO) and the stratospheric atmospheric circulations in the Arctic and Antarctic, respectively. After filtering out high-frequency components from the temporal evolutions of these modes, a significant 11-year cycle was observed in the Antarctic stratospheric atmospheric circulation mode, potentially linked to the 11-year solar cycle. In contrast, the Arctic stratospheric atmospheric circulation mode showed a 5–6-year cycle without evidence of an 11-year periodicity. This difference is likely due to the timing of polar vortex breakdowns: the Antarctic polar vortex breaks up later, experiencing its greatest variability in late spring and early summer, making it more susceptible to solar radiation effects, unlike the Arctic polar vortex, which peaks in winter and early spring. The fourth mode exhibits characteristics of a Southern Hemisphere dipole and shows a significant correlation with the Antarctic stratospheric atmospheric circulation mode, leading it by about two months. We designed a linear prediction model that successfully demonstrated its predictive capability for the Antarctic polar vortex. Full article

Therapeutic efficacy of histidyl dipeptides such as carnosine is hampered by circulating carnosinase-1 (CN1), which catalyzes carnosine’s hydrolysis and degradation. Prior reports suggest that oral carnosine may improve cardiometabolic parameters in patients with heart failure (HF), but whether CN1 activity is affected by HF is unknown. Here, we measured CN1 content and carnosine degradation rate (CDR) in preoperative plasma samples from a cohort of patients (n = 138) undergoing elective cardiac surgery to determine whether plasma CN1 and/or CDR varied with left ventricular (LV) systolic dysfunction. CN1 content was normally distributed in the cohort, but plasma CDR displayed a quasi-bimodal distribution into high- (>2 nmol/(h*μL)) and low-activity (≤2 nmol/(h*μL)) clusters. Multivariable analysis confirmed female sex, diabetes and LV systolic dysfunction was associated with the low-activity CDR cluster. Although CN1 content did not differ, logistic regression analysis revealed that CDR and CN1-specific activity (CDR/CN1 content) was significantly lower in patients with both moderate (ejection fraction, EF ≥ 35 to <50%) and severe LV systolic dysfunction (EF < 35%) compared with patients in the normal range (EF ≥ 50%). These findings suggest that plasma CN1 activity is regulated by factors independent of expression, and that a decline in LV systolic function is associated with low CN1 activity. Further studies are needed to delineate specific mechanisms controlling CN1 expression and activity, which will facilitate the development of carnosine and other histidyl dipeptide therapies for cardiometabolic disorders such as HF. Full article

In this study, our aim is to diagnose how two quasi-linear convective systems (QLCS) are organized so one can determine the possible role of the city of Chicago, IL, USA, in modifying convective precipitation systems. In this Part I of a two-part study, we employ large-scale analyses, radiosonde soundings, surface observations, and Doppler radar data to diagnose the precursor atmospheric circulations that organize the evolution of two mesoscale convective systems and compare those circulations to radar and precipitation. Several multi-scale processes are found that organize and modify convection over the Chicago metroplex. Two sequential quasi-linear convective systems (QLCS #1 and #2) were organized that propagated over Chicago, IL, USA, during an eight-hour period on 5–6 July 2018. The first squall line (QLCS #1) built from the southwest to the northeast while strengthening as it propagated over the city, and the second (QLCS #2) propagated southeastwards and weakened as it passed over the city in association with a polar cold front. The weak upper-level divergence associated with a diffluent flow poleward of an expansive ridge built over and strengthened a low-level trough and confluence zone, triggering QLCS #1. Convective downdrafts from QLCS #1 produced a cold pool that interacted with multiple confluent low-level jets surrounding and focused on the metroplex urban heat island, thus advecting the convection poleward over the metroplex. The heaviest precipitation occurred just south-southeast of Midway Airport, Chicago. Subsequently, a polar cold front propagated into the metroplex, which triggered QLCS #2. However, the descending air above it under the polar jet and residual cold pool from QLCS #1 rapidly dissipated the cold frontal convection. This represents a case study where very active convection built over the metroplex and was likely modified by it, as evidenced in numerical simulations to be described in Part II. Full article

The metabolic response to a maximal exercise test in physically inactive adults remains poorly understood, particularly regarding the role of adiponectin, an adipokine with insulin-sensitizing and anti-inflammatory properties. Adiponectin circulates in three isoforms—low (LMW), medium (MMW), and high-molecular-weight (HMW)—with differing bioactivities. While exercise is known to influence adiponectin levels, evidence is conflicting, and few studies have explored isoform-specific changes. This study aimed to evaluate the effects of a single maximal exercise session on circulating adiponectin isoforms and their associations with metabolic and kidney function markers in physically inactive young adults. In this quasi-experimental study, twenty-one physically inactive participants (mean age 24.6 ± 2.1 years, 85.7% women) completed a progressive cycle ergometer test. Circulating levels of LMW and MMW adiponectin, metabolic outcomes (e.g., cholesterol, triglycerides, fibroblast growth factor 21 (FGF21)), and kidney function markers (e.g., creatinine, proteinuria) were assessed before and after exercise using biochemical assays and Western blotting. Comparisons between pre- and post-exercise values were made with the Wilcoxon test. Exercise increased lipid metabolism markers (total cholesterol, triglycerides, HDL) and kidney stress indicators (albuminuria, proteinuria) (p < 0.05). LMW and MMW adiponectin levels showed no significant overall changes, but LMW adiponectin positively correlated with changes in total cholesterol and FGF21, while MMW adiponectin negatively correlated with creatinine and proteinuria (p < 0.05). HMW adiponectin was undetectable by our methods. A single maximal exercise session revealed isoform-specific associations between adiponectin and metabolic or kidney stress markers, emphasizing the complex role of adiponectin in exercise-induced metabolic responses. Future research should explore mechanisms underlying these differential associations to optimize exercise interventions for metabolic health improvement. Full article