Table of Contents
Molecules, Volume 22, Issue 8 (August 2017)
- Issues are regarded as officially published after their release is announced to the table of contents alert mailing list.
- You may sign up for e-mail alerts to receive table of contents of newly released issues.
- PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.
Cover Story (view full-size image) Enzymatically synthesized LacNAc tetrasaccharides were conjugated to BSA protein scaffolds by [...] Read more. Enzymatically synthesized LacNAc tetrasaccharides were conjugated to BSA protein scaffolds by squarate linker chemistry. Resulting multivalent neo-glycoproteins were further studied for specific binding of the tumor-associated human galectin 3 (Gal-3) and its truncated counterpart Gal-3∆. We observed a significantly increased affinity of Gal-3∆ to neo-glycoproteins presenting LacNAc type 1 repeating units. This is the first evidence for differences in glycan selectivity of Gal-3∆ and Gal-3 and may be further utilized for tracing Gal-3∆ during tumor progression and therapy. View this paper