Table of Contents
Cells, Volume 7, Issue 5 (May 2018)
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Cover Story (view full-size image) Autophagy is a selective physiological process through which organisms eliminate toxic [...] Read more. Autophagy is a selective physiological process through which organisms eliminate toxic intracellular aggregates. Modern research in animal model organisms and humans indicates that autophagy declines during ageing. The impairment of autophagy promotes neurodegeneration in elderly individuals and shortens lifespan. Recent experimental findings suggest that autophagy inducers counteract the age-related progression of neurodegenerative disorders and boost healthspan and longevity. View the paper here.