Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic. The journal’s Editor-in-Chief and/or designated EBM will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Oral Squamous Cell Carcinoma: Molecular Signaling Pathways and Novel Biomarkers
edited by
submission deadline 31 Jul 2024 | 2 articles | Viewed by 2145 | Submission Open
Keywords: oral squamous cell carcinoma (OSCC); molecular signaling pathways; biomarkers; pathogenesis; targeted therapy; tumour growth; tumour invasion; angiogenesis; tumour metastasis; immune response modulation
(This special issue belongs to the Section Cancer Biology and Oncology)
Drug Target: Identification and Mechanism of Action
edited by Srijan Acharya
submission deadline 31 Jul 2024 | 1 articles | Viewed by 2096 | Submission Open
Keywords: pharmacology; drug discovery; drug targets; receptors function; target validation; chemical biology; lead optimization
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Molecular Mechanisms of Antibody-Mediated Rejection and Accommodation in Kidney Transplantation
edited by and Ayman Al Jurdi
submission deadline 31 Jul 2024 | 2 articles | Viewed by 2076 | Submission Open
Keywords: kidney transplant; transplant immunology; recurrent glomerular disease; clinical trials; rejection; crossmatching; allocation; CMV; BK nephropathy
(This special issue belongs to the Section Molecular and Translational Medicine)
Genetics of Chronic Disease
edited by Vicente Andreu-Fernández and
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1899 | Submission Open
Keywords: pathophysiology of chronic disease; complex diseases; genetic disorders; SNP microarrays; whole genome or exome sequencing; molecular diagnostics; epigenetics; obesity; diabetes mellitus; neurodevelopmental disease; neurodegenerative disease
(This special issue belongs to the Section Gene and Cell Therapy)
The Role of Ion Channels and Transporters in Human Health and Diseases
edited by Teresa Soda
submission deadline 31 Jul 2024 | 2 articles | Viewed by 1832 | Submission Open
Keywords: ion channels; transporters; ion pumps; voltage-gated channels; ionotropic receptors; TRP channels; store-operated channels; Piezo channels; NALCN channels; inositol-1; 4; 5-receptors; ryanodine receptors; two-pore channels; synaptic transmission; channelopathies; neurodegenerative disorders; cardiovascular disorders
(This special issue belongs to the Section Cell Biology and Pathology)
Skin Tissue Regeneration and Wound Healing
edited by and
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1623 | Submission Open
Keywords: inflammation; wound healing; scarring; regeneration
(This special issue belongs to the Section Cell Biology and Pathology)
Oral Cancer: From Pathophysiology to Novel Therapeutic Approaches Volume II submission deadline 31 Jul 2024 | 1 articles | Viewed by 1277 | Submission Open
Keywords: oral carcinogenesis; oral tumorigenesis; oral cancer; OSCC; ICI; mutation; biomarkers; chemoradiation; targeted therapies; cisplatin; preclinical models
(This special issue belongs to the Section Molecular and Translational Medicine)
Age-Related Macular Degeneration: Causes, Pathogenesis, Diagnosis, and Intervention
edited by David Pei-Cheng Lin
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1157 | Submission Open
Keywords: age-related macular degeneration (AMD); risk factors; prevention; pathogenesis; intervention
(This special issue belongs to the Section Molecular and Translational Medicine)
Mitochondria in Human Health and Diseases
edited by
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1129 | Submission Open
Keywords: mitochondrial biology; stem cells; cell growth and differentiation; immune cells; inflammation; autoimmunity; diabetes; neurodegenerative diseases; aging; clinical trials
(This special issue belongs to the Section Cell Biology and Pathology)
Emerging Strategies for Early Detection and Prevention of Atherosclerotic Cardiovascular Disease
edited by , Tsung-Ying Tsai and Pruthvi C Revaiah
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1063 | Submission Open
Keywords: subclinical atherosclerosis; atherosclerotic cardiovascular disease (ASCVD); early detection; non-invasive imaging; biomarkers; lipid-lowering therapy; anti-inflammation therapy; gene therapy; risk stratification
(This special issue belongs to the Section Molecular and Translational Medicine)
Novel Approaches towards Targeted Head and Neck Cancer Therapies
edited by
submission deadline 31 Jul 2024 | 1 articles | Viewed by 1030 | Submission Open
Keywords: EGFR; VEGFR; RET; MET; PI3K; radiotherapy; chemotherapy; immunotherapy; HPV; preclinical HNSCC model; biomarkers of treatment response
(This special issue belongs to the Section Cancer Biology and Oncology)
Development of Bone Anabolic Agents and Scaffolds for Improved Fracture Healing
edited by Subhashis Pal
submission deadline 31 Jul 2024 | 1 articles | Viewed by 991 | Submission Open
Keywords: bone anabolic agents; fracture healing; nonunion fracture; osteoblast; gut– bone axis for fracture healing; probiotics; osteoporotic fracture; tissue scaffold for fracture healing
(This special issue belongs to the Section Biomedical Engineering and Materials)
Extracellular Matrix in Health and Disorders
edited by
submission deadline 31 Jul 2024 | 1 articles | Viewed by 990 | Submission Open
Keywords: ECM; connective tissue; healthy tissues; pathological tissues; imaging; drug targets; markers; dermis; bone; tendon
(This special issue belongs to the Section Molecular and Translational Medicine)
Disease Biomarkers in the Precision Medicine Era: A Comprehensive Multi-omics Analysis
edited by
submission deadline 31 Jul 2024 | 1 articles | Viewed by 794 | Submission Open
Keywords: personalized medicine; disease biomarkers: screening and diagnosis; multi-omics analysis; epidemiology
(This special issue belongs to the Section Molecular and Translational Medicine)
Inflammaging and Immunosenescence: Mechanisms and Link
edited by
submission deadline 31 Jul 2024 | Viewed by 746 | Submission Open
Keywords: inflammaging; immunosenescence; autoimmune disease; age-related disease; aging
(This special issue belongs to the Section Immunology and Immunotherapy)
Molecular Mechanism in Inflammation and Immunity
edited by Anella Saviano
submission deadline 31 Jul 2024 | 1 articles | Viewed by 655 | Submission Open
Keywords: adaptive immunity; autoimmune-based diseases; cyto/chemokines; inflammation; macrophages; natural compounds; nutraceuticals; signaling pathway in arachidonic acid cascade; T-cells; trained immunity
(This special issue belongs to the Section Cell Biology and Pathology)
Neuroinflammation: From Pathophysiologic Mechanisms to Therapeutic Strategies
edited by Li-Ping Zhou
submission deadline 31 Jul 2024 | 1 articles | Viewed by 606 | Submission Open
Keywords: neuroinflammation; molecular mechanism; anti-inflammation; stem cell-based therapy; cell-free stem-cell-based therapy; immunomodulation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Crohn's Disease and Ulcerative Colitis: From Pathophysiology to Novel Therapeutic Approaches (2nd Edition)
edited by
submission deadline 31 Jul 2024 | 1 articles | Viewed by 590 | Submission Open
Keywords: inflammatory bowel disease; crohn's disease; ulcerative colitis; chronic inflammation; pathophysiological mechanisms; therapeutic approaches; stem cell transplantation; fecal microbiota transplantation; gut microbiome; targeted therapies
(This special issue belongs to the Section Immunology and Immunotherapy)
New Molecular Insights into the Pathogenesis and Drug Development of Neurodegenerative Diseases
edited by Aifang Cheng and Beika Zhu
submission deadline 31 Jul 2024 | Viewed by 570 | Submission Open
Keywords: neurodegenerative diseases; pathogenesis; molecular mechanisms; high-throughput drug screening; drug repurposing; cellular and animal models; brain organoids; mode of action; pharmacological evaluations; preclinical study
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Targets to Enhance the Radiation Effect and Overcome Radiation Resistance in Cancer
edited by
submission deadline 31 Jul 2024 | Viewed by 364 | Submission Open
Keywords: radioresistance; radiosensitivity; radiotherapy; targeted therapy; radioligand; immunotherapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Diagnosis, Pathogenesis, Treatment and Prognosis of Glioblastoma
edited by Paulo Linhares
submission deadline 31 Jul 2024 | 1 articles | Viewed by 359 | Submission Open
Keywords: glioblastoma; immunotherapy; molecular subtype; radiotherapy; molecular therapy; emerging treatment; drug resistance; MRI; immune surveillance
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Peripheral Artery Disease and Diabetic Foot Ulcer: From Bench to Clinic (2nd Edition) submission deadline 31 Jul 2024 | Viewed by 330 | Submission Open
Keywords: peripheral artery diseases; diabetic foot ulcer; atherosclerosis; regenerative medicine; inflammatory
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advanced Research on Drugs Against Breast Cancer: From Bench to Bedside
edited by Lunawati Bennett
submission deadline 31 Jul 2024 | Viewed by 316 | Submission Open
Keywords: breast cancer; drug discovery; therapeutic targets; preclinical studies; clinical trials; molecular mechanism; biomarkers; drug resistance; combination therapies; translational research
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of Angiotensin-II in the Cardiovascular System: From Molecular Mechanism to Therapeutic Perspectives
edited by Shubha Ranjan Dutta
submission deadline 31 Jul 2024 | Viewed by 284 | Submission Open
Keywords: renin– angiotensin system; inflammation; eicosanoids; arachidonic acid; cytosolic phospholipase A2α ; vasoconstrictor
(This special issue belongs to the Section Molecular and Translational Medicine)
Biosensors and Nanotechnology for Drug Discovery and Development
edited by and Ajay Kumar Yagati
submission deadline 31 Jul 2024 | Viewed by 273 | Submission Open
Keywords: drug delivery; nanotechnology; pharmaceutics; biosensors; drug discovery and development
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Immune Checkpoints and Autoimmunity — Volume II
edited by
submission deadline 31 Jul 2024 | Viewed by 271 | Submission Open
Keywords: immune checkpoint molecules; autoimmune diseases; inflammatory diseases; checkpoint inhibitor therapy; inflammation
(This special issue belongs to the Section Immunology and Immunotherapy)
RAS Signaling in Cancer
edited by
submission deadline 31 Jul 2024 | Viewed by 256 | Submission Open
Keywords: RAS/MAPK signaling; cancer metabolism; drug resistance; targeted cancer therapy; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research in Heme Oxygenase submission deadline 31 Jul 2024 | Viewed by 256 | Submission Open
Keywords: heme oxygenase; bilirubin; iron; biliverdin reductase; ferritin; feroapoptosis; carbon monoxide
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathological Biomarkers in Precision Medicine
edited by , Mirela A. Dobre and Tudor Groza
submission deadline 31 Jul 2024 | Viewed by 249 | Submission Open
Keywords: pathological biomarkers; precision medicine; artificial intelligence; medical imaging; omics data analysis; personalized medicine; biomarker discovery; digital pathology
(This special issue belongs to the Section Cell Biology and Pathology)
Role of Bone Marrow Niche in Haematological Cancers submission deadline 31 Jul 2024 | Viewed by 216 | Submission Open
Keywords: blood cancers; bone marrow; microenvironment; immune stromal interactions; mesenchymal stem cells
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular Research in Neuropharmacology
edited by
submission deadline 31 Jul 2024 | Viewed by 216 | Submission Open
Keywords: molecular mechanism; cellular pathway; neuropharmacology; therapeutics; agonist; antagonist; neuroinflammation; neurodegeneration; glial cells; neurons
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Role of Placenta-Derived Mesenchymal Stem Cells in Human Health and Disease
edited by Luca Giacomello
submission deadline 31 Jul 2024 | Viewed by 212 | Submission Open
(This special issue belongs to the Section Cell Biology and Pathology)
Drug Resistance and Novel Targets for Cancer Therapy—Second Edition submission deadline 31 Jul 2024 | Viewed by 210 | Submission Open
Keywords: cancer; drug resistance; targeted therapy; conventional chemotherapy; natural products; molecular targets; cancer hallmarks; therapeutic agents
(This special issue belongs to the Section Cancer Biology and Oncology)
Mechanisms and Novel Therapeutic Approaches for Gliomas
edited by Maria V. Chatziathanasiadou
submission deadline 31 Jul 2024 | Viewed by 187 | Submission Open
Keywords: glioma; molecular mechanisms; signaling; tumour immunity; tumour metabolism; tumour microenvironment; metabolic therapies; immunotherapies; combination treatment
(This special issue belongs to the Section Cancer Biology and Oncology)
Role of Macrophages and Gut Microbiota in Liver Diseases
edited by
submission deadline 31 Jul 2024 | Viewed by 177 | Submission Open
Keywords: macrophages; gut microbiota; liver diseases; immune response; inflammation; fibrosis; microbial dysbiosis; therapeutic interventions; treatment targets
(This special issue belongs to the Section Molecular and Translational Medicine)
Essential Oils: Pharmacological Activities and Potential Use As Therapeutic Agents
edited by Diogo Vilar Da Fonsêca and Damião Pergentino De Sousa
submission deadline 31 Jul 2024 | Viewed by 171 | Submission Open
Keywords: flavors; aroma; inhalation; biological activity; diabetes; anxiety; depression; epilepsy; ulcers; cancer
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
From Molecules to Medicine: Deciphering Obesity and Lipid Metabolism for Translational Insights submission deadline 31 Jul 2024 | Viewed by 157 | Submission Open
Keywords: obesity; insulin resistance; lipid metabolism; drug discovery
(This special issue belongs to the Section Molecular and Translational Medicine)
Regulatory T Cells in Neuroimmunological Disease Therapeutics submission deadline 31 Jul 2024 | Viewed by 156 | Submission Open
Keywords: Treg; multiple sclerosis; Alzheimer's disease; Parkinson's disease; depression; immune therapy; immunomodulation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Next-Generation Sequencing and Proteomics Research for Retinal Diseases
edited by Jayshree Advani
submission deadline 31 Jul 2024 | Viewed by 139 | Submission Open
Keywords: genomics; proteomics; biomarker; variant interpretation; single-molecule sequencing; epigenome; retinal degeneration; genetics
(This special issue belongs to the Section Molecular and Translational Medicine)
Translational Research on Angiogenesis and Related Disorders
edited by
submission deadline 31 Jul 2024 | Viewed by 132 | Submission Open
Keywords: angiogenesis; cardiovascular diseases; cancers; diabetic complications; therapeutic target; biomarkers; drug development; clinical implementation
(This special issue belongs to the Section Molecular and Translational Medicine)
Epigenetic Mechanisms of Postoperative Cognitive Impairment Induced by Anesthesia and Neuroinflammation
edited by Rump Katharina
submission deadline 31 Jul 2024 | Viewed by 128 | Submission Open
Keywords: cognitive impairment; postoperative delirium; postoperative cognitive dysfunction; neuroinflammation; DNA methyltransferase; HDAC. HAT; epigenetics; DNA methylation; histone modification; RNAi
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
mTOR Signaling in Disease and Therapy
edited by Wenjing Yu and
submission deadline 31 Jul 2024 | Viewed by 118 | Submission Open
Keywords: mTOR signaling; tissue engineering; stem cell; disease; therapy; bone; craniofacial; biomedicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Induced Pluripotent Stem Cells
edited by
submission deadline 31 Jul 2024 | Viewed by 117 | Submission Open
Keywords: induced pluripotent stem cells; organoids; tissue engineering; biomaterials; reprogramming; iPSC-based cell modelling; cell therapy; microfluidics; drug discovery
(This special issue belongs to the Section Gene and Cell Therapy)
Molecular Targets for Biological Therapies of Severe Asthma: Second Edition
edited by
submission deadline 31 Jul 2024 | Viewed by 111 | Submission Open
Keywords: IgE; IL-5; IL-4; IL-13; cytokine receptors; TSLP; monoclonal antibodies; omalizumab; mepolizumab; reslizumab; benralizumab; dupilumab; tezepelumab
(This special issue belongs to the Section Immunology and Immunotherapy)
Myelodysplastic Syndromes: Advances and Challenges in Pathophysiology and Therapeutic Approaches
edited by Maria Cuzzola
submission deadline 31 Jul 2024 | Viewed by 110 | Submission Open
Keywords: myelodysplastic syndrome; molecular pathology; immunotherapy; thalidomide and its analogues; hematopoietic stem cell transplantation
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Atherothrombotic Diseases
edited by
submission deadline 31 Jul 2024 | Viewed by 109 | Submission Open
Keywords: atherothrombosis; cardiovascular risk factors; atherosclerosis; endothelial cells; vascular smooth muscle cells; platelets; cardiovascular events
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Mechanisms and Treatment of Rheumatic Diseases
edited by Ruxandra Ionescu and
submission deadline 31 Jul 2024 | Viewed by 99 | Submission Open
Keywords: rheumatology; immune-mediated rheumatic diseases; biologics; DMARDs; arthritis; lupus; vasculitis; spondyloarthritis; targets
(This special issue belongs to the Section Molecular and Translational Medicine)
CAR-T Cell Therapy in Hematological Malignancies
edited by Patrick Schlegel
submission deadline 31 Jul 2024 | Viewed by 96 | Submission Open
Keywords: target validation for hematological cancers; next-generation CAR T to overcome the TME; combinatorial CAR therapies; dual-targeting; triple-targeting; complementary CAR strategies
(This special issue belongs to the Section Immunology and Immunotherapy)
Mitochondrial Dysfunction and Oxidative Stress
edited by
submission deadline 31 Jul 2024 | Viewed by 96 | Submission Open
Keywords: mitochondria; oxidative stress; brain metabolism; neurodevelopmental diseases; neuropsychiatric diseases; neurodegenerative diseases; mitochondrial medicine; translational medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Recent Advances in Craniofacial Pain and Headaches—Second Edition submission deadline 31 Jul 2024 | Viewed by 95 | Submission Open
Keywords: craniofacial pain; headache; migraine; painful temporomandibular disorders; orofacial pain; biomedical advances; treatment; assessment; innovation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
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