Genetic Testing for Cancer Susceptibility
A special issue of Genes (ISSN 2073-4425). This special issue belongs to the section "Human Genomics and Genetic Diseases".
Deadline for manuscript submissions: 15 May 2024 | Viewed by 1482
Special Issue Editors
Interests: inherited cancer susceptibility and molecular analysis
Interests: gene variants; functional studies; signal transduction; gene regulation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Research advances combined with improvements in technologies are deeply modifying the knowledges of cancer susceptibility, generating, simultaneously, news and unexpected scenarios.
Different challenges are now represented by the evidence of overlapping genetic syndromes, findings of incidental variants, and difficulties in correlations between variants and interpretations. These have a large impact on risk estimate, prognosis, and tailored therapies outcomes.
This Special Issue arises from the need for meaningful risk data on genetic susceptibility obtained by cutting-edge research to improve the clinical interpretation of germline multi-gene panel testing.
Research articles, reviews, as well as short communications are invited to submit to this Special Issue. Research topics of interest include, but are not limited to:
- Data from multigenic panel applied in real world;
- Functional validation of phenotype-specific genetic variations through in vitro and in vivo models;
- Machine learning approaches in the prediction of pathogenic variants;
- Reinterpretation/reclassification of gene variants;
- Innovative methodologies such as liquid biopsy;
- Inherited disorders studies useful to understand pathological pathways in oncogenesis and discover new clinical biomarkers or actionable alleles for precision medicine;
- Population-based studies of founder mutations in specified populations or ethnicities.
Dr. Francesco Baudi
Dr. Rodolfo Iuliano
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Genes is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- hereditary cancer predisposition syndromes
- cancer predisposition genes
- hereditary cancer risk
- precision medicine for cancer syndromes
- germline panel testing
- pathogenic variants
