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Molecules
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Biodegradation: Organic, Medicinal and Analytical Chemistry
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Biodegradation: Organic, Medicinal and Analytical Chemistry

A special issue of Molecules (ISSN 1420-3049). This special issue belongs to the section "Organic Chemistry".

Deadline for manuscript submissions: closed (31 July 2009) | Viewed by 18085

Special Issue Editors

Dr. Shu-Kun Lin

E-Mail Website
Managing Editor
MDPI, St. Alban-Anlage 66, CH-4052 Basel, Switzerland
Interests: gibbs paradox; entropy; symmetry; similarity; diversity; information theory; thermodynamics; process irreversibility or spontaneity; stability; nature of the chemical processes; molecular recognition; open access journals
Prof. Dr. Naozumi Teramoto

E-Mail Website
Editorial Advisor
Department of Applied Chemistry, Faculty of Engineering, Chiba Institute of Technology, 2-17-1 Tsudanuma, Narashino, Chiba 275-0016, Japan
Interests: biomaterial; bio-based polymer; bioplastics; biodegradable polymer; biopolymer; composite material comprising a polymer matrix
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

To protect environment, the biodegradable materials have great advantage. However, sometimes, for material stability, biodegradation is a problem, for example, the biomedical materials.

Keywords

  • biodegradable polymers, organics or materials

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739 KiB  
Review
Design and Applications of Biodegradable Polyester Tissue Scaffolds Based on Endogenous Monomers Found in Human Metabolism
by Devin G. Barrett and Muhammad N. Yousaf
Molecules 2009, 14(10), 4022-4050; https://doi.org/10.3390/molecules14104022 - 12 Oct 2009
Cited by 87 | Viewed by 17610
Abstract
Synthetic polyesters have deeply impacted various biomedical and engineering fields, such as tissue scaffolding and therapeutic delivery. Currently, many applications involving polyesters are being explored with polymers derived from monomers that are endogenous to the human metabolism. Examples of these monomers include glycerol, [...] Read more.
Synthetic polyesters have deeply impacted various biomedical and engineering fields, such as tissue scaffolding and therapeutic delivery. Currently, many applications involving polyesters are being explored with polymers derived from monomers that are endogenous to the human metabolism. Examples of these monomers include glycerol, xylitol, sorbitol, and lactic, sebacic, citric, succinic, α-ketoglutaric, and fumaric acids. In terms of mechanical versatility, crystallinity, hydrophobicity, and biocompatibility, polyesters synthesized partially or completely from these monomers can display a wide range of properties. The flexibility in these macromolecular properties allows for materials to be tailored according to the needs of a particular application. Along with the presence of natural monomers that allows for a high probability of biocompatibility, there is also an added benefit that this class of polyesters is more environmentally friendly than many other materials used in biomedical engineering. While the selection of monomers may be limited by nature, these polymers have produced or have the potential to produce an enormous number of successes in vitro and in vivo. Full article
(This article belongs to the Special Issue Biodegradation: Organic, Medicinal and Analytical Chemistry)
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