A special issue of Sensors (ISSN 1424-8220). This special issue belongs to the section "Biosensors".
Deadline for manuscript submissions: closed (31 October 2012)
Special Issue Editor
Prof. Dr. Akiyoshi Taniguchi
1 Advanced Medical Materials Group, Biomaterials Center, National Institute for Materials Science (NIMS), 1-1 Namiki, Tsukuba-shi Ibaraki, 305-004 Japan 2 Wased University-NIMS Joint Graduate Program, 1-1 Namiki, Tsukuba, Ibaraki, Japan
Fax: +81 29 860 4714 Interests: cell- based biosensor; nanotoxicology; in vitro co-culture; microfluidics
Special Issue Information
Living cells maintain life functions by responding quickly and with great sensitivity to changes in the external environment. Consequently, sensors using live cells are thought to be able to perform analyses faster and with more sensitivity than previously possible. Cell-based sensors can be roughly divided into two types. The first uses microorganisms such as Escherichia coli or yeast as sensing elements (Microbial cells). The second type uses human and animal cells (Mammalian cells). The first type can be cultivated rather easily and has the advantages of being inexpensive and portable. The second type is more complex but has the advantage of potentially being used with human subjects. Most research in this area is concentrated on the first type, microbial sensors, but research on sensors that use mammalian cells has recently become more widespread. Live cell-based sensors may potentially be used as an evaluation technology in medical and pharmaceutical fields, as well as for cytotoxicity inspection of medical supplies, nanomaterials, biomaterials, environmental factors and other materials. The special issue of the journal Sensors will cover these different types of live cell-based sensors and applications for these different fields.