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  • Current Issues in Molecular Biology is published by MDPI from Volume 43 Issue 1 (2021). Previous articles were published by another publisher in Open Access under a CC-BY (or CC-BY-NC-ND) licence, and they are hosted by MDPI on mdpi.com as a courtesy and upon agreement with Caister Press.

Current Issues in Molecular Biology, Volume 34, Issue 1

2019 December - 11 articles

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Articles (11)

  • Review
  • Open Access
47 Citations
1,917 Views
12 Pages

The insect virome is composed of a myriad of viruses. Both field populations and laboratory colonies of insects harbour diverse viruses, including viruses that infect the insect itself, viruses of microbes associated with the insect, and viruses asso...

  • Review
  • Open Access
41 Citations
1,669 Views
17 Pages

Modern genomic sequencing and bioinformatics approaches have detected numerous examples of DNA sequences derived from DNA and RNA virus genomes integrated into both vertebrate and insect genomes. Retroviruses encode RNA-dependent DNA polymerases (rev...

  • Review
  • Open Access
6 Citations
1,078 Views
30 Pages

Sensing Viral Infections in Insects: A Dearth of Pathway Receptors

  • Loïc Talide,
  • Jean-Luc Imler and
  • Carine Meignin

Insects, the most diverse group of animals, can be infected by an extraordinary diversity of viruses. Among them, arthropod-borne viruses can be transmitted to humans, while bee and silkworm viruses cause important economic losses. Like all invertebr...

  • Review
  • Open Access
9 Citations
1,111 Views
21 Pages

Micro-RNA Modulation of Insect Virus Replication

  • Verna Monsanto-Hearne and
  • Karyn N. Johnson

The outcome of virus infection in insects is impacted by regulation of both host and virus gene expression. A class of small RNAs called micro-RNAs (miRNA) have emerged as important regulators of gene expression that can influence the outcome of viru...

  • Review
  • Open Access
20 Citations
1,553 Views
30 Pages

Dicistrovirus-Host Molecular Interactions

  • Reid Warsaba,
  • Jibin Sadasivan and
  • Eric Jan

Members of the family Dicistroviridae are small RNA viruses containing a monopartite positive-sense RNA genome. Dicistroviruses mainly infect arthropods, causing diseases that impact agriculture and the economy. In this chapter, we provide an overvie...

  • Review
  • Open Access
17 Citations
1,246 Views
32 Pages

Insects in the orders Hemiptera and Thysanoptera transmit viruses and other pathogens associated with the most serious diseases of plants. Plant viruses transmitted by these insects target similar tissues, genes, and proteins within the insect to fac...

  • Review
  • Open Access
7 Citations
1,152 Views
17 Pages

Advances in Tetravirus Research: New Insight into the Infectious Virus Lifecycle and an Expanding Host Range

  • Rosemary Ann Dorrington,
  • Meesbah Jiwaji,
  • Janet Awino Awando and
  • Mart-Mari de Bruyn

Tetraviruses are a group of relatively unknown small RNA viruses with particles that display a characteristic T=4 capsid architecture. Tetraviruses are classified into three families, the Alphatetraviridae, Permutotetraviridae and Carmotetraviridae,...

  • Review
  • Open Access
41 Citations
1,347 Views
19 Pages

Polydnaviruses: Evolution and Function

  • Michael R. Strand and
  • Gaelen R. Burke

Polydnaviruses (PDVs) were originally viewed as large DNA viruses that are beneficial symbionts of parasitoid wasps. Two groups of PDVs were also recognized: bracoviruses (BVs), which are associated with wasps in the family Braconidae, and ichnovirus...

  • Review
  • Open Access
19 Citations
1,862 Views
32 Pages

Baculoviridae constitutes a family of insect-specific, large DNA viruses with a unique life cycle characterized by the production of two morphologically distinct virions, the budded virus (BV) and the occlusion-derived virus (ODV). ODV and BV, with d...

  • Review
  • Open Access
37 Citations
2,374 Views
16 Pages

Recent Developments in the Use of Baculovirus Expression Vectors

  • Robert D. Possee,
  • Adam C. Chambers,
  • Leo P. Graves,
  • Mine Aksular and
  • Linda A. King

Over 35 years since it was established to make recombinant proteins, the baculovirus expression vector system continues to develop and improve. Early systems for recombinant virus selection were laborious, but better methods were rapidly devised that...

  • Review
  • Open Access
34 Citations
2,086 Views
25 Pages

Baculovirus as Versatile Vectors for Protein Display and Biotechnological Applications

  • Chih-Hsuan Tsai,
  • Sung-Chan Wei,
  • Huei-Ru Lo and
  • Yu-Chan Chao

The baculovirus-insect cell system has long been deployed for a variety of applications including for use as biopesticides, for recombinant protein production, transient transgene expression, tissue therapy, and for vaccine production. Apart from the...

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Curr. Issues Mol. Biol. - ISSN 1467-3045