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Journal of Xenobiotics, Volume 14, Issue 4

December 2024 - 35 articles

Cover Story: Endocrine-disrupting chemicals (EDCs) are substances that interfere with hormonal processes, posing significant health risks. Polyphenols are natural compounds abundantly present in our diet in fruits, vegetables, tea, coffee, and wine, which exhibit both protective and disruptive effects on EDC activity. Their antioxidant and anti-inflammatory properties can mitigate EDC-induced damage, yet their phytoestrogenic nature dysregulates hormone activity. This review explores the dual role of polyphenols, highlighting their potential to both counteract and amplify EDC effects. Understanding their interactions is crucial for developing strategies to minimize the health risks associated with EDC exposure while harnessing the beneficial properties of polyphenols. View this paper
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Articles (35)

  • Review
  • Open Access
7 Citations
2,498 Views
37 Pages

19 December 2024

Dibutyl phthalate (DBP) is a low-molecular-weight phthalate commonly found in personal care products, such as perfumes, aftershaves, and nail care items, as well as in children’s toys, pharmaceuticals, and food products. It is used to improve f...

  • Article
  • Open Access
1 Citations
1,265 Views
24 Pages

Effects of the Interaction of Salinity and Rare Earth Elements on the Health of Mytilus galloprovincialis: The Case of Praseodymium and Europium

  • Carla Leite,
  • Tania Russo,
  • Gianluca Polese,
  • Amadeu M. V. M. Soares,
  • Carlo Pretti,
  • Eduarda Pereira and
  • Rosa Freitas

18 December 2024

The growing use of products containing rare earth elements (REEs) may lead to higher environmental emissions of these elements, which can potentially enter aquatic systems. Praseodymium (Pr) and europium (Eu) are widely used REEs with various applica...

  • Article
  • Open Access
2 Citations
1,209 Views
12 Pages

18 December 2024

Short- and medium-chain chlorinated paraffins (SCCPs and MCCPs) are environmental contaminants known for their persistence and bioaccumulation in fatty tissues. SCCPs are considered potential carcinogens and endocrine disruptors, with similar effects...

  • Article
  • Open Access
1,341 Views
15 Pages

16 December 2024

The direct discharge of cationic surfactants into environmental matrices has exponentially increased due to their wide application in many products. These compounds and their degraded products disrupt microbial dynamics, hinder plant survival, and af...

  • Article
  • Open Access
2,108 Views
26 Pages

In Silico Analysis of Triamterene as a Potential Dual Inhibitor of VEGFR-2 and c-Met Receptors

  • Stuart Lutimba,
  • Baraya Saleem,
  • Eiman Aleem and
  • Mohammed A. Mansour

14 December 2024

The vascular endothelial growth factor receptor 2 (VEGFR2) and the hepatocyte growth factor receptor (C-Met) are critical receptors for signaling pathways controlling crucial cellular processes such as cell growth, angiogenesis and tissue regeneratio...

  • Article
  • Open Access
2,942 Views
21 Pages

Assessment of Chicken Fecal Contamination Using Microbial Source Tracking (MST) and Environmental DNA (eDNA) Profiling in Silway River, Philippines

  • Lonny Mar Opog,
  • Joan Cecilia Casila,
  • Rubenito Lampayan,
  • Marisa Sobremisana,
  • Abriel Bulasag,
  • Katsuhide Yokoyama and
  • Soufiane Haddout

12 December 2024

The Silway River has historically failed to meet safe fecal coliform levels due to improper waste disposal. The river mouth is located in General Santos City, the tuna capital of the Philippines and a leading producer of hogs, cattle, and poultry. Th...

  • Article
  • Open Access
4 Citations
1,303 Views
11 Pages

5 December 2024

Nanoplastics are known to represent a threat to marine ecosystems. Their combination with other contaminants of emerging concerns (CECs) may amplify ecotoxic effects, with unknown impacts on marine biodiversity. This study investigates the effects, s...

  • Article
  • Open Access
1 Citations
1,159 Views
11 Pages

Potential Toxicity of Nine Rare Earth Elements (REEs) on Marine Copepod Tigriopus fulvus

  • Francesca Biandolino,
  • Ermelinda Prato,
  • Asia Grattagliano,
  • Giovanni Libralato,
  • Marco Trifuoggi and
  • Isabella Parlapiano

4 December 2024

The present study focused, for the first time, on the adverse effects of nine REEs on the marine copepod Tigriopus fulvus. For this purpose, copepod mortality, immobilization, and naupliar development were assessed. Overall, the results demonstrated...

  • Review
  • Open Access
6 Citations
5,004 Views
18 Pages

Overview of Computational Toxicology Methods Applied in Drug and Green Chemical Discovery

  • Jose I. Bueso-Bordils,
  • Gerardo M. Antón-Fos,
  • Rafael Martín-Algarra and
  • Pedro A. Alemán-López

4 December 2024

In the field of computational chemistry, computer models are quickly and cheaply constructed to predict toxicology hazards and results, with no need for test material or animals as these computational predictions are often based on physicochemical pr...

  • Article
  • Open Access
1,742 Views
12 Pages

Analysis of Thiodiphenol in Rat Urine as a Biomarker of Exposure to Temephos

  • Miao-Ling Shih,
  • Ma. de Lourdes López-González,
  • Marisela Uribe-Ramírez,
  • Aurora Elizabeth Rojas-García,
  • Francisco Alberto Verdín-Betancourt and
  • Adolfo Sierra-Santoyo

4 December 2024

Temephos is an organophosphorus pesticide widely used as a larvicide in public health campaigns to control vector-borne diseases. Data on the urinary elimination of temephos metabolites are limited, and there is no validated biomarker of exposure for...

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J. Xenobiot. - ISSN 2039-4713Creative Common CC BY license