Oil depots are continuous sources of volatile organic compounds (VOCs), which contribute to ground-level ozone (O
3) and secondary organic aerosol formation, posing threats to air quality and public health. This study investigated typical crude and refined oil depots in the Xigu District of Lanzhou by measuring VOC source profiles and establishing an emission inventory. The maximum incremental reactivity (MIR) method was applied to assess the chemical reactivity of VOCs; both the emission inventory and VOC profiles were incorporated into the WRF-CMAQ model for numerical simulations. Results showed that the average ambient VOC concentrations were 49.8 μg/m
3 for the crude oil depot and 66.1 μg/m
3 for the refined oil depot. The crude oil depot was dominated by alkanes (37.1%), aromatics (25.1%), and OVOCs (22.5%), while the refined oil depot was dominated by alkanes (57.3%) and OVOCs (16.7%), with isopentane identified as the most abundant species in both depots. The ozone formation potentials (OFPs) of the crude oil and refined oil depots were 153.1 μg/m
3 and 178.3 μg/m
3, respectively. Aromatics (47.0%) and OVOCs (29.0%) were the primary contributors at the crude oil depot, with isopentane, o-xylene, etc., as the dominant reactive species. In the refined oil depot, the main contributors were alkanes (27.8%), alkenes and alkynes (26.6%), OVOCs (24.5%), and aromatics (20.5%), among which isopentane, trans-2-butene, etc., were most prominent. In 2023, VOC emissions from the crude oil and refined oil depots were estimated at 1605.3 t and 1287.8 t, respectively, mainly from working loss (96.6%) in the crude oil depot and deck fitting loss (60.7%) and working loss (31.3%) in the refined oil depot. Numerical simulations indicated that oil depot emissions could increase regional MDA8 O
3 concentrations by up to 40.0 μg/m
3. At the nearby Lanlian Hotel site, emissions contributed 15.1% of the MDA8 O
3, equivalent to a 6.1 μg/m
3 increase, while the citywide average was 1.7 μg/m
3. This study enriches the VOC source profile database for oil depots, reveals their significant role in regional O
3 formation, and provides a scientific basis for precise O
3 control and differentiated emission reduction strategies in Northwest China.
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