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Pathogens, Volume 11, Issue 1

2022 January - 109 articles

Cover Story: Helicobacter pylori is a gastric pathogen that exploits multiple host signaling pathways, leading to the disruption of key cell functions. Two bacterial virulence factors play important roles in this scenario, the vacuolating cytotoxin VacA and the translocated effector protein CagA of the cag type IV secretion system (T4SS). Specifically, by overruling the phosphorylation status of cortactin, H. pylori alternates the activity of molecular interaction partners of this important protein, thereby manipulating the performance of cytoskeletal rearrangements, endosomal trafficking, and cell movement. Here, we found that cortactin is necessary for the effective induction of T4SS- and CagA-dependent AGS cell movement and elongation but is dispensable for VacA uptake and formation of VacA-dependent vacuole formation and cell apoptosis. View this paper.
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Articles (109)

  • Article
  • Open Access
12 Citations
6,509 Views
11 Pages

Prevalence of Toxoplasma gondii Measured by Western Blot, ELISA and DNA Analysis, by PCR, in Cats of Western Mexico

  • María de la Luz Galván-Ramírez,
  • Claudia Charles-Niño,
  • César Pedroza-Roldán,
  • Carolina Salazar-Reveles and ,
  • Karen Lissete Ocampo-Figueroa,
  • Laura Roció Rodríguez-Pérez and
  • Varinia Margarita Paez-Magallán
  • + 2 authors+ 0 author

17 January 2022

Toxoplasma gondii is the causative agent of toxoplasmosis in humans and animals. The sexual reproductive cycle of Toxoplasma takes place in the small intestine of felines, the definitive hosts. In the final part of the sexual cycle, T. gondii forms o...

(This article belongs to the Section Parasitic Pathogens)
  • Article
  • Open Access
1 Citations
2,708 Views
7 Pages

An Artefactual Cluster of Mycobacterium abscessus Pneumonia among Cancer Patients Arising from Contamination

  • Giusy Diella,
  • Giuseppina Caggiano,
  • Francesco Triggiano,
  • Marco Lopuzzo and ,
  • Francesca Apollonio,
  • Michele Mastria,
  • Luigi Ronga,
  • Lucia Bonadonna,
  • Luca Lucentini and
  • Maria Teresa Montagna
  • + 7 authors+ 2 authors

17 January 2022

The Mycobacteriumabscessus complex (MABC) is a group of rapidly growing, nontuberculous mycobacteria that are ubiquitous in soil, urban water pipes, swimming pools, and drinking water. Members of the MABC are considered opportunistic pathogens. The a...

  • Article
  • Open Access
4 Citations
3,672 Views
8 Pages

West Nile Virus in Common Wild Avian Species in Israel

  • Gili Schvartz,
  • Sharon Tirosh-Levy,
  • Shahar Bider,
  • Avishai Lublin and ,
  • Yigal Farnoushi,
  • Oran Erster and
  • Amir Steinman
  • + 2 authors+ 0 author

17 January 2022

In order to evaluate the contribution of different wild bird species to West Nile virus (WNV) circulation in Israel, during the months preceding the 2018 outbreak that occurred in Israel, we randomly sampled 136 frozen carcasses of a variety of avian...

(This article belongs to the Collection Feature Papers in Viral Pathogens)
  • Article
  • Open Access
20 Citations
5,621 Views
17 Pages

Molecular Detection of Tick-Borne Agents in Cats from Southeastern and Northern Brazil

  • Marcos Rogério André,
  • Ana Cláudia Calchi,
  • Maria Eduarda Chiaradia Furquim,
  • Isabela de Andrade and ,
  • Paulo Vitor Cadina Arantes,
  • Lara Cristina de Melo Lopes,
  • Iuri Kauan Lins do Nascimento Demarchi,
  • Mayra Araguaia Pereira Figueiredo,
  • Cirilo Antonio de Paula Lima and
  • Rosangela Zacarias Machado
  • + 5 authors+ 0 author

16 January 2022

Even though the epidemiology of tick-borne agents (TBA) in dogs has been extensively investigated around the world, the occurrence, vectors involved, and molecular identity of these agents in cats remains elusive in many regions. Among TBA, Ehrlichia...

(This article belongs to the Section Parasitic Pathogens)
  • Article
  • Open Access
19 Citations
4,913 Views
14 Pages

Giardia duodenalis in Wildlife: Exploring Genotype Diversity in Italy and across Europe

  • Isabel Guadano Procesi,
  • Margherita Montalbano Di Filippo,
  • Claudio De Liberato,
  • Andrea Lombardo and ,
  • Giuseppina Brocherel,
  • Stefania Perrucci,
  • David Di Cave and
  • Federica Berrilli
  • + 3 authors+ 0 author

16 January 2022

Fragmented data are so far available on genotype diversity of G. duodenalis in wildlife in different countries in Europe, in particular, in Italy. In the present study, G. duodenalis sequences obtained from different Italian wild animals [12 porcupin...

(This article belongs to the Special Issue Parasitic Diseases of Domestic, Wild, and Exotic Animals)
  • Article
  • Open Access
12 Citations
5,643 Views
14 Pages

Phenotypic Selection of Dairy Cattle Infected with Bovine Leukemia Virus Demonstrates Immunogenetic Resilience through NGS-Based Genotyping of BoLA MHC Class II Genes

  • Chaelynne E. Lohr,
  • Kelly R. B. Sporer,
  • Kelsey A. Brigham,
  • Laura A. Pavliscak and ,
  • Matelyn M. Mason,
  • Andrew Borgman,
  • Vickie J. Ruggiero,
  • Tasia M. Taxis,
  • Paul C. Bartlett and
  • Casey J. Droscha
  • + 5 authors+ 0 author

15 January 2022

Characterization of the bovine leukocyte antigen (BoLA) DRB3 gene has shown that specific alleles associate with susceptibility or resilience to the progression of bovine leukemia virus (BLV), measured by proviral load (PVL). Through surveillance of...

(This article belongs to the Collection Bovine Leukemia Virus Infection)
  • Review
  • Open Access
31 Citations
9,674 Views
23 Pages

15 January 2022

The protozoan Cryptosporidium parvum is one of the major causative pathogens of diarrhoea in young ruminants; therefore, it causes economic losses and impairs animal welfare. Besides C. parvum, there are many other non-infectious and infectious facto...

(This article belongs to the Special Issue Zoonotic Parasitoses)
  • Communication
  • Open Access
13 Citations
3,466 Views
7 Pages

Endothelium Activation during Severe Yellow Fever Triggers an Intense Cytokine-Mediated Inflammatory Response in the Liver Parenchyma

  • Fábio Alves Olímpio,
  • Luiz Fábio Magno Falcão,
  • Marcos Luiz Gaia Carvalho,
  • Jeferson da Costa Lopes and ,
  • Caio Cesar Henriques Mendes,
  • Arnaldo Jorge Martins Filho,
  • Carlos Augusto Moreira da Silva,
  • Vanessa do Socorro Cabral Miranda,
  • Lais Carneiro dos Santos and
  • Juarez Antônio Simões Quaresma
  • + 13 authors+ 8 authors

15 January 2022

Yellow fever (YF) is a pansystemic disease caused by the yellow fever virus (YFV), the prototype species of the family Flaviviridae and genus Flavivirus, and has a highly complex host-pathogen relationship, in which endothelial dysfunction reflects v...

(This article belongs to the Section Parasitic Pathogens)
  • Review
  • Open Access
2 Citations
4,813 Views
15 Pages

Regulatory Role of Phospholipids in Hepatitis C Virus Replication and Protein Function

  • Anna V. Bulankina,
  • Rebecca M. Richter and
  • Christoph Welsch

15 January 2022

Positive-strand RNA viruses such as hepatitis C virus (HCV) hijack key factors of lipid metabolism of infected cells and extensively modify intracellular membranes to support the viral lifecycle. While lipid metabolism plays key roles in viral partic...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
15 Citations
3,543 Views
15 Pages

Avian Macrophage Responses to Virulent and Avirulent Clostridium perfringens

  • Raveendra R. Kulkarni,
  • Carissa Gaghan and
  • Javid Mohammed

15 January 2022

The present study evaluated the avian macrophage responses against Clostridium perfringens that varied in their ability to cause necrotic enteritis in chickens. Strains CP5 (avirulent-netB+), CP1 (virulent-netB+), and CP26 (highly virulent-netB+tpeL+...

(This article belongs to the Section Immunological Responses and Immune Defense Mechanisms)
  • Review
  • Open Access
12 Citations
4,289 Views
13 Pages

15 January 2022

Human babesiosis results from a combination of tick tropism for humans, susceptibility of a host to sustain Babesia development, and contact with infected ticks. Climate modifications and increasing diagnostics have led to an expanded number of Babes...

(This article belongs to the Special Issue Babesia and Human Babesiosis)
  • Brief Report
  • Open Access
7 Citations
3,035 Views
8 Pages

Avian Bornaviruses in Wild Aquatic Birds of the Anseriformes Order in Poland

  • Edyta Świętoń,
  • Kamila Dziadek and
  • Krzysztof Śmietanka

15 January 2022

Bornaviruses are a diverse family of viruses infecting various hosts, including birds. Aquatic bird bornavirus 1 (ABBV-1) and aquatic bird bornavirus 2 (ABBV-2) have been found in wild waterfowl but data on their prevalence are scarce. To gain knowle...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
20 Citations
4,134 Views
11 Pages

Genetic Characterization and Variation of African Swine Fever Virus China/GD/2019 Strain in Domestic Pigs

  • Xun Wang,
  • Xiaoying Wang,
  • Xiaoxiao Zhang,
  • Sheng He and ,
  • Yaosheng Chen,
  • Xiaohong Liu and
  • Chunhe Guo
  • + 2 authors+ 0 author

14 January 2022

African swine fever (ASF) was first introduced into Northern China in 2018 and has spread through China since then. Here, we extracted the viral DNA from the blood samples from an ASF outbreak farm in Guangdong province, China and sequenced the whole...

(This article belongs to the Collection Feature Papers in Viral Pathogens)
  • Review
  • Open Access
5 Citations
2,886 Views
10 Pages

14 January 2022

Sepsis remains an important source of morbidity and mortality in children, despite the development of standardized care. In the last decades, there has been an increased interest in genetic and genomic approaches to early recognition and development...

(This article belongs to the Section Immunological Responses and Immune Defense Mechanisms)
  • Article
  • Open Access
30 Citations
4,889 Views
9 Pages

HERV-K and HERV-H Env Proteins Induce a Humoral Response in Prostate Cancer Patients

  • Maria Antonietta Manca,
  • Tatiana Solinas,
  • Elena Rita Simula,
  • Marta Noli and ,
  • Stefano Ruberto,
  • Massimo Madonia and
  • Leonardo A. Sechi
  • + 2 authors+ 0 author

14 January 2022

A higher expression of human endogenous retroviruses (HERVs) has been associated with several malignancies, including prostate cancer, implying a possible use as a diagnostic or prognostic cancer biomarker. For this reason, we examined the humoral re...

(This article belongs to the Section Immunological Responses and Immune Defense Mechanisms)
  • Perspective
  • Open Access
34 Citations
6,427 Views
13 Pages

The Conserved Macrodomain Is a Potential Therapeutic Target for Coronaviruses and Alphaviruses

  • Anthony K. L. Leung,
  • Diane E. Griffin,
  • Jürgen Bosch and
  • Anthony R. Fehr

14 January 2022

Emerging and re-emerging viral diseases pose continuous public health threats, and effective control requires a combination of non-pharmacologic interventions, treatment with antivirals, and prevention with vaccines. The COVID-19 pandemic has demonst...

(This article belongs to the Special Issue ADP-Ribosylation in Pathogens)
  • Article
  • Open Access
6 Citations
3,572 Views
15 Pages

Effect of Female Sex Hormones on the Immune Response against Chlamydia abortus and on Protection Conferred by an Inactivated Experimental Vaccine in a Mouse Model

  • Laura Del Rio,
  • Antonio Murcia-Belmonte,
  • Antonio Julián Buendía,
  • Jose Antonio Navarro and ,
  • Nieves Ortega,
  • Daniel Alvarez,
  • Jesús Salinas and
  • María Rosa Caro
  • + 3 authors+ 0 author

14 January 2022

Mice are valuable models extensively used to test vaccine candidates against Chlamydia abortus and to clarify immunopathological mechanisms of the bacteria. As this pathogen has the ability to reactivate during pregnancy, it is important to deepen th...

(This article belongs to the Special Issue Transmissible Diseases Affecting Reproduction in Small Ruminants)
  • Article
  • Open Access
8 Citations
4,308 Views
16 Pages

Fatty Acid Profiles of Leishmania major Derived from Human and Rodent Hosts in Endemic Cutaneous Leishmaniasis Areas of Tunisia and Algeria

  • Cyrine Bouabid,
  • Yoshiki Yamaryo-Botté,
  • Sameh Rabhi,
  • Haifa Bichiou and ,
  • Chaima Hkimi,
  • Wafa Bouglita,
  • Melek Chaouach,
  • Naouel Eddaikra,
  • Kais Ghedira and
  • Imen Rabhi
  • + 7 authors+ 2 authors

14 January 2022

Leishmaniasis is a protozoal vector-borne disease that affects both humans and animals. In the Mediterranean Basin, the primary reservoir hosts of Leishmania spp. are mainly rodents and canids. Lipidomic approaches have allowed scientists to establis...

  • Article
  • Open Access
17 Citations
4,538 Views
11 Pages

13 January 2022

SCUBA divers are predisposed to otitis externa caused by Pseudomonas aeruginosa, which is becoming increasingly multi-drug resistant (MDR). The present work assessed the antibiotic resistance profiles of P. aeruginosa obtained from SCUBA divers and t...

(This article belongs to the Section Bacterial Pathogens)
  • Systematic Review
  • Open Access
31 Citations
11,290 Views
23 Pages

13 January 2022

Filth flies, cockroaches, and dung beetles have been close neighbors with humans and animals throughout our joint histories. However, these insects can also serve as vectors for many zoonotic enteric parasites (ZEPs). Zoonoses by ZEPs remain a paramo...

(This article belongs to the Special Issue Zoonotic Parasitoses)
  • Review
  • Open Access
25 Citations
6,809 Views
17 Pages

Ecology of Ixodes pacificus Ticks and Associated Pathogens in the Western United States

  • Molly McVicar,
  • Isabella Rivera,
  • Jeremiah B. Reyes and
  • Monika Gulia-Nuss

13 January 2022

Lyme disease is the most important vector-borne disease in the United States and is increasing in incidence and geographic range. In the Pacific west, the western black-legged tick, Ixodes pacificus Cooley and Kohls, 1943 is an important vector of th...

(This article belongs to the Special Issue Current Research on Hard Tick-Borne Diseases)
  • Brief Report
  • Open Access
3 Citations
3,620 Views
7 Pages

12 January 2022

Gurltia paralysans, a metastrongyloid nematode, parasitizes in meningeal vessels in the thoracolumbar spinal cord of cats in South America and causes progressive paraparesis. Recently, the first report outside of South America described gurltiosis in...

(This article belongs to the Section Parasitic Pathogens)
  • Article
  • Open Access
11 Citations
3,712 Views
14 Pages

Multi-Dimensionality Immunophenotyping Analyses of MAIT Cells Expressing Th1/Th17 Cytokines and Cytotoxic Markers in Latent Tuberculosis Diabetes Comorbidity

  • Gokul Raj Kathamuthu,
  • Nathella Pavan Kumar,
  • Kadar Moideen,
  • Chandrakumar Dolla and ,
  • Paul Kumaran and
  • Subash Babu
  • + 1 author+ 0 author

12 January 2022

Mucosal-associated invariant T (MAIT) cells are innate like, and play a major role in restricting disease caused by Mycobacterium tuberculosis (Mtb) disease before the activation of antigen-specific T cells. Additionally, the potential link and syner...

  • Article
  • Open Access
58 Citations
10,389 Views
16 Pages

Biological Control of Fusarium culmorum, Fusarium graminearum and Fusarium poae by Antagonistic Yeasts

  • Izabela Podgórska-Kryszczuk,
  • Ewa Solarska and
  • Monika Kordowska-Wiater

11 January 2022

The genus Fusarium is considered to be one of the most pathogenic, phytotoxic and toxin-producing group of microorganisms in the world. Plants infected by these fungi are characterized by a reduced consumer and commercial value, mainly due to the con...

(This article belongs to the Special Issue Elimination of Pathogenic Microorganisms by Natural and Synthetic Compounds)
  • Article
  • Open Access
4 Citations
3,033 Views
11 Pages

Deltamethrin Application on Pre-Weaned Calves Improves Feed Consumption, Stress and Fatigue Status under Heat Stress Conditions

  • Konstantinos V. Arsenopoulos,
  • Eleftherios Triantafillou,
  • Athanasios I. Gelasakis and
  • Elias Papadopoulos

11 January 2022

Fly infestation remains a universal problem for dairy cattle herds, affecting the animals’ health and welfare status. Pre-weaned dairy calves are significantly challenged by the direct and indirect consequences of severe fly infestation, heat-s...

(This article belongs to the Special Issue Update of Animal Parasitic Diseases)
  • Article
  • Open Access
41 Citations
5,349 Views
11 Pages

The Periodontopathic Pathogen, Porphyromonas gingivalis, Involves a Gut Inflammatory Response and Exacerbates Inflammatory Bowel Disease

  • Yu-Chen Lee,
  • Chih-Yi Liu,
  • Chia-Long Lee,
  • Ruo-Han Zhang and ,
  • Chi-Jung Huang and
  • Ting-Lin Yen
  • + 1 author+ 0 author

11 January 2022

Periodontal disease (PD) is one of the most prevalent disorders globally and is strongly associated with many other diseases. Inflammatory bowel disease (IBD), an inflammatory condition of the colon and the small intestine, is reported to be associat...

  • Article
  • Open Access
8 Citations
7,245 Views
17 Pages

Ultraviolet-C Irradiation, Heat, and Storage as Potential Methods of Inactivating SARS-CoV-2 and Bacterial Pathogens on Filtering Facepiece Respirators

  • Rhodri Harfoot,
  • Deborah B. Y. Yung,
  • William A. Anderson,
  • Cervantée E. K. Wild and ,
  • Nicolene Coetzee,
  • Leonor C. Hernández,
  • Blair Lawley,
  • Daniel Pletzer,
  • José G. B. Derraik and
  • Miguel E. Quiñones-Mateu
  • + 6 authors+ 1 author

10 January 2022

The arrival of SARS-CoV-2 to Aotearoa/New Zealand in February 2020 triggered a massive response at multiple levels. Procurement and sustainability of medical supplies to hospitals and clinics during the then upcoming COVID-19 pandemic was one of the...

(This article belongs to the Special Issue 10th Anniversary of Pathogens—Emerging and Re-emerging Viral Pathogens in a Pandemic World)
  • Article
  • Open Access
4 Citations
3,928 Views
17 Pages

10 January 2022

Symbiotic microorganisms in the intestinal tract can influence the general fitness of their hosts and contribute to protecting them against invading pathogens. In this study, we obtained isolate Phytobacter diazotrophicus SCO41 from the gut of free-l...

  • Case Report
  • Open Access
7 Citations
3,749 Views
9 Pages

Xanthogranulomatous Pyelonephritis Caused by Stenotrophomonas maltophilia—The First Case Report and Brief Review

  • Răzvan-Cosmin Petca,
  • Răzvan-Alexandru Dănău,
  • Răzvan-Ionuț Popescu,
  • Daniel Damian and ,
  • Cristian Mareș,
  • Aida Petca and
  • Viorel Jinga
  • + 2 authors+ 0 author

10 January 2022

Xanthogranulomatous pyelonephritis (XGP) represents a rare and severe pathology secondary to chronic urinary obstruction and recurrent infections. Commonly, this condition leads to loss of kidney function, and frequently, surgical approach is the onl...

(This article belongs to the Section Bacterial Pathogens)
  • Review
  • Open Access
31 Citations
11,427 Views
9 Pages

Some patients with chronic rhinitis have a positive nasal allergen provocation test (NAPT) without systemic IgE sensitization by skin prick tests or serum allergen-specific IgE (sIgE). This novel concept is called local allergic rhinitis (LAR) and af...

(This article belongs to the Special Issue Allergy and Immunotherapy)
  • Review
  • Open Access
71 Citations
9,558 Views
17 Pages

Porcine Deltacoronaviruses: Origin, Evolution, Cross-Species Transmission and Zoonotic Potential

  • Fanzhi Kong,
  • Qiuhong Wang,
  • Scott P. Kenney,
  • Kwonil Jung and ,
  • Anastasia N. Vlasova and
  • Linda J. Saif
  • + 1 author+ 0 author

Porcine deltacoronavirus (PDCoV) is an emerging enteropathogenic coronavirus of swine that causes acute diarrhoea, vomiting, dehydration and mortality in seronegative neonatal piglets. PDCoV was first reported in Hong Kong in 2012 and its etiological...

(This article belongs to the Special Issue Emerging and/or Zoonotic Viral Infections)
  • Article
  • Open Access
23 Citations
5,725 Views
13 Pages

Odontogenic Cervicofacial Necrotizing Fasciitis: Microbiological Characterization and Management of Four Clinical Cases

  • Sebastian Böttger,
  • Silke Zechel-Gran,
  • Daniel Schmermund,
  • Philipp Streckbein and ,
  • Jan-Falco Wilbrand,
  • Michael Knitschke,
  • Jörn Pons-Kühnemann,
  • Torsten Hain,
  • Markus Weigel and
  • Sameh Attia
  • + 8 authors+ 3 authors

Necrotizing fasciitis of the head and neck is a rare, very severe disease, which, in most cases, originates from odontogenic infections and frequently ends with the death of the patient. Rapid surgical intervention in combination with a preferably pa...

(This article belongs to the Special Issue Opportunistic Oral Pathogens in Oral and Systemic Diseases)
  • Article
  • Open Access
6 Citations
4,349 Views
10 Pages

Quantitative Risk Assessment of African Swine Fever Introduction into Spain by Legal Import of Live Pigs

  • Carolina Muñoz-Pérez,
  • Jaime Bosch,
  • Satoshi Ito,
  • Marta Martínez-Avilés and
  • José Manuel Sánchez-Vizcaíno

African swine fever (ASF) is a devastating infectious disease of pigs that is threatening the global swine industry at present. The current spread of ASF in Europe and its recent incursion into Germany pose a serious risk to Spain, one of the world&r...

(This article belongs to the Special Issue African Swine Fever: Epidemiology, Design of New Diagnostic Methods and Vaccine Development)
  • Review
  • Open Access
20 Citations
6,042 Views
12 Pages

Vaccines for Mycoplasma Diseases of Small Ruminants: A Neglected Area of Research

  • Katarzyna Dudek,
  • Umit Sevimli,
  • Sergio Migliore,
  • Amirreza Jafarizadeh and ,
  • Guido R. Loria and
  • Robin A. J. Nicholas
  • + 1 author+ 0 author

Mycoplasmas cause some of the most economically important diseases of sheep and goats, including diseases listed by the World Organisation for Animal Health (OIE) such as contagious caprine pleuropneumonia (CCPP) and contagious agalactia (CA). Other...

  • Review
  • Open Access
27 Citations
7,484 Views
14 Pages

Arboviral Disease Outbreaks in the Pacific Islands Countries and Areas, 2014 to 2020: A Systematic Literature and Document Review

  • Rosie J. Matthews,
  • Ishani Kaluthotage,
  • Tanya L. Russell,
  • Tessa B. Knox and ,
  • Paul F. Horwood and
  • Adam T. Craig
  • + 1 author+ 0 author

Arthropod-borne diseases pose a significant public health threat, accounting for greater than 17% of infectious disease cases and 1 million deaths annually. Across Pacific Island countries and areas (PICs), outbreaks of dengue, chikungunya, and Zika...

(This article belongs to the Special Issue One Health and Transboundary Diseases)
  • Article
  • Open Access
21 Citations
4,483 Views
11 Pages

Amphotericin B Polymer Nanoparticles Show Efficacy against Candida Species Biofilms

  • Abdulghani Alakkad,
  • Paul Stapleton,
  • Corinna Schlosser,
  • Sudaxshina Murdan and ,
  • Uchechukwu Odunze,
  • Andreas Schatzlein and
  • Ijeoma F. Uchegbu
  • + 2 authors+ 0 author

Purpose: Chronic infections of Candida albicans are characterised by the embedding of budding and entwined filamentous fungal cells into biofilms. The biofilms are refractory to many drugs and Candida biofilms are associated with ocular fungal infect...

(This article belongs to the Section Fungal Pathogens)
  • Article
  • Open Access
20 Citations
4,807 Views
15 Pages

Salmonella causes significant economic loss to the poultry industry and represents a real threat to human health. The region of difference 21 (ROD21) pathogenicity island removal is a genetic mechanism by which Salmonellaenteritidis (SE) invades the...

(This article belongs to the Section Bacterial Pathogens)
  • Article
  • Open Access
5 Citations
3,941 Views
11 Pages

Rabies Vaccination in Dogs in Laos: Owner Knowledge and Serological Status of Dogs

  • Lovisa Velander,
  • Johanna Fogelberg,
  • Vannaphone Putthana,
  • Amphone Keosengthong and
  • Johanna Frida Lindahl

Rabies is an infectious disease which is virtually 100% fatal. Humans are most often infected through the bite of an infected dog, and most cases could be prevented by vaccinating dogs. However, vaccination coverage is insufficient in most countries...

(This article belongs to the Topic Zoonoses in Tropical Countries)
  • Article
  • Open Access
14 Citations
3,906 Views
13 Pages

Regulatory Effect of Irresistin-16 on Competitive Dual-Species Biofilms Composed of Streptococcus mutans and Streptococcus sanguinis

  • Xiangyu Hu,
  • Min Wang,
  • Yan Shen,
  • Lingjun Zhang and ,
  • Yihuai Pan,
  • Yan Sun and
  • Keke Zhang
  • + 2 authors+ 0 author

Based on the ecological plaque hypothesis, suppressing opportunistic pathogens within biofilms, rather than killing microbes indiscriminately, could be a biofilm control strategy for managing dental caries. The present study aimed to evaluate the eff...

(This article belongs to the Special Issue Insights in Oral Microbiota)
  • Review
  • Open Access
18 Citations
5,208 Views
9 Pages

Atopic dermatitis (AD) is a condition with a complex and unclear aetiology. Possible causes of AD encompass alterations in the structure and function of the epidermal barrier, disturbances in the skin microbiome, immune factors, allergens, bacterial...

(This article belongs to the Section Immunological Responses and Immune Defense Mechanisms)
  • Article
  • Open Access
11 Citations
5,558 Views
16 Pages

Detection of Circulating VZV-Glycoprotein E-Specific Antibodies by Chemiluminescent Immunoassay (CLIA) for Varicella–Zoster Diagnosis

  • Arnaud John Kombe Kombe,
  • Jiajia Xie,
  • Ayesha Zahid,
  • Huan Ma and ,
  • Guangtao Xu,
  • Yiyu Deng,
  • Fleury Augustin Nsole Biteghe,
  • Ahmed Mohammed,
  • Zhao Dan and
  • Tengchuan Jin
  • + 11 authors+ 6 authors

Varicella and herpes zoster are mild symptoms-associated diseases caused by varicella–zoster virus (VZV). They often cause severe complications (disseminated zoster), leading to death when diagnoses and treatment are delayed. However, most comm...

(This article belongs to the Special Issue Characterization of Antibody Responses to Virus Infections in Humans)
  • Article
  • Open Access
16 Citations
3,743 Views
15 Pages

Six-Month Follow-Up after Vaccination with BNT162b2: SARS-CoV-2 Antigen-Specific Cellular and Humoral Immune Responses in Hemodialysis Patients and Kidney Transplant Recipients

  • Simone Cosima Boedecker-Lips,
  • Anja Lautem,
  • Stefan Runkel,
  • Pascal Klimpke and ,
  • Daniel Kraus,
  • Philipp Keil,
  • Stefan Holtz,
  • Vanessa Tomalla,
  • Paul Marczynski and
  • Julia Weinmann-Menke
  • + 8 authors+ 3 authors

Hemodialysis patients (HDP) and kidney transplant recipients (KTR) have a high risk of infection with SARS-CoV-2 with poor clinical outcomes. Because of this, vaccination of these groups of patients against SARS-CoV-2 is particularly important. Howev...

(This article belongs to the Section Viral Pathogens)
  • Article
  • Open Access
10 Citations
3,849 Views
20 Pages

The E3 Ubiquitin Ligase ATL9 Affects Expression of Defense Related Genes, Cell Death and Callose Deposition in Response to Fungal Infection

  • Tingwei Guo,
  • Feng Kong,
  • Carter Burton,
  • Steven Scaglione and ,
  • Blake Beagles,
  • Justin Ray and
  • Katrina M. Ramonell
  • + 2 authors+ 0 author

Plants use diverse strategies to defend themselves from biotic stresses in nature, which include the activation of defense gene expression and a variety of signal transduction pathways. Previous studies have shown that protein ubiquitination plays a...

(This article belongs to the Special Issue 10th Anniversary of Pathogens—Feature Papers)
  • Review
  • Open Access
36 Citations
15,060 Views
17 Pages

The Bovine Tuberculoid Granuloma

  • Mitchell V. Palmer,
  • Carly Kanipe and
  • Paola M. Boggiatto

The bovine tuberculoid granuloma is the hallmark lesion of bovine tuberculosis (bTB) due to Mycobacterium bovis infection. The pathogenesis of bTB, and thereby the process of bovine tuberculoid granuloma development, involves the recruitment, activat...

(This article belongs to the Special Issue Immunopathogenesis and Diagnostics to Control Tuberculosis in Cattle and Wildlife)
  • Article
  • Open Access
14 Citations
3,702 Views
12 Pages

News Insights into the Host-Parasite Interactions of Amyloodiniosis in European Sea Bass: A Multi-Modal Approach

  • Michela Massimo,
  • Donatella Volpatti,
  • Marco Galeotti,
  • James E. Bron and
  • Paola Beraldo

Amyloodiniosis is a disease resulting from infestation by the ectoparasitic dinoflagellate Amyloodinium ocellatum (AO) and is a threat for fish species such as European sea bass (ESB, Dicentrarchus labrax), which are farmed in lagoon and land-based r...

(This article belongs to the Section Parasitic Pathogens)
  • Article
  • Open Access
8 Citations
3,598 Views
11 Pages

Predominance of Acinetobacter spp., Harboring the blaIMP Gene, Contaminating the Hospital Environment in a Tertiary Hospital in Mwanza, Tanzania: A Cross-Sectional Laboratory-Based Study

  • Vitus Silago,
  • Eveline C. Mruma,
  • Betrand Msemwa,
  • Conjester I. Mtemisika and ,
  • Shukurani Phillip,
  • Reuben A. Ndagula,
  • Maria M. Said,
  • Martha F. Mushi and
  • Stephen E. Mshana
  • + 4 authors+ 0 author

Data on colonization and hospital contamination of carbapenem-resistant Gram-negative bacteria (CR-GNB) are limited in low- and middle-income countries. We designed this study to determine the prevalence and co-existence of carbapenemase genes among...

(This article belongs to the Special Issue Resistant Mechanisms and Novel Antibiotics of Carbapenem-Resistant Crisis)
  • Review
  • Open Access
49 Citations
8,423 Views
16 Pages

Current Understanding of the Pathogenesis of Porcine Circovirus 3

  • Chaitawat Sirisereewan,
  • Roongroje Thanawongnuwech and
  • Roongtham Kedkovid

Circoviruses are closed, circular, single-stranded DNA viruses belonging to the family Circoviridae and the genus Circovirus. To date, at least four porcine circoviruses (PCVs) have been recognized, including PCV1 to PCV4, respectively. Similar to PC...

(This article belongs to the Special Issue The Advanced Research on Porcine Circovirus)
  • Article
  • Open Access
8 Citations
4,028 Views
11 Pages

Analysis of the Effects of Food Additives on Porphyromonas gingivalis

  • Mai Shinohara,
  • Miki Maetani,
  • Chiharu Kitada,
  • Yasuko Nishigami and ,
  • Ayaka Yazawa and
  • Shigeki Kamitani
  • + 1 author+ 0 author

This study aims to investigate six food additives (octanoic acid, decanoic acid, acesulfame K, aspartame, saccharin, and sucralose) used in foods for the elderly or people with dysphagia because of the effect of these food additives on Porphyromonas ...

  • Article
  • Open Access
13 Citations
4,719 Views
28 Pages

Embedding of HIV Egress within Cortical F-Actin

  • Anupriya Aggarwal,
  • Alberto Ospina Stella,
  • Catherine C. Henry,
  • Kedar Narayan and
  • Stuart G. Turville

F-Actin remodeling is important for the spread of HIV via cell–cell contacts; however, the mechanisms by which HIV corrupts the actin cytoskeleton are poorly understood. Through live cell imaging and focused ion beam scanning electron microscop...

(This article belongs to the Section Immunological Responses and Immune Defense Mechanisms)

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Pathogens - ISSN 2076-0817