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Microorganisms, Volume 7, Issue 3

2019 March - 31 articles

Cover Story: Mycobacterial membrane protein large (MmpL) proteins are integral membrane transporters that export large, complex substrates across the plasma membrane of Mycobacterium tuberculosis (Mtb). These substrates play an essential role in Mtb’s physiology and enable its specialized lifestyle as a human pathogen. This review summarizes recent advancements in our understanding of the basis of MmpL-mediated transport and the contribution of MmpL-exported substrates to the virulence and pathogenicity of Mtb in a human host. View this paper.
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Articles (31)

  • Article
  • Open Access
7 Citations
4,042 Views
15 Pages

The experiment was to determine the chronic effects of two transgenic maize lines that contained the mCry1Ac gene from the Bacillus thuringiensis strain (BT) and the maroACC gene from Agrobacterium tumefaciens strain (CC), respectively, on ileal micr...

  • Review
  • Open Access
76 Citations
10,277 Views
25 Pages

Minimally processed and ready-to-eat (RTE) seafood products are gaining popularity because of their availability in retail stores and the consumers’ perception of convenience. Products that are subjected to mild processing and products that do not re...

  • Review
  • Open Access
147 Citations
16,249 Views
17 Pages

Mycobacterium abscessus: Environmental Bacterium Turned Clinical Nightmare

  • Rose C. Lopeman,
  • James Harrison,
  • Maya Desai and
  • Jonathan A. G. Cox

Mycobacteria are a large family of over 100 species, most of which do not cause diseases in humans. The majority of the mycobacterial species are referred to as nontuberculous mycobacteria (NTM), meaning they are not the causative agent of tuberculou...

  • Article
  • Open Access
14 Citations
4,980 Views
12 Pages

Plant growth promoting rhizobacteria (PGPR) are associated with plant roots and augment plant productivity and immunity by reducing fertilizer application rates and nutrient runoff. Studies were conducted to evaluate bell pepper transplants amended w...

  • Article
  • Open Access
15 Citations
11,436 Views
23 Pages

Forty-two Rhizoctonia isolates were collected from rice, mung bean, and grasses from Laguna, Philippines. Sixteen isolates were binucleate Rhizoctonia (BNR), while 26 were multinucleate Rhizoctonia (MNR). BNR isolates produced white to brown, small s...

  • Article
  • Open Access
56 Citations
6,930 Views
9 Pages

Among non-mammalian infection model organisms, the larvae of the greater wax moth Galleria mellonella have seen increasing popularity in recent years. Unlike other invertebrate models, these larvae can be incubated at 37 °C and can be dosed relat...

  • Article
  • Open Access
26 Citations
5,452 Views
11 Pages

Microbiological Testing for the Proper Assessment of the Hygiene Status of Beef Carcasses

  • Anderson Carlos Camargo,
  • Marcus Vinícius Coutinho Cossi,
  • Wladimir Padilha da Silva,
  • Luciano dos Santos Bersot,
  • Mariza Landgraf,
  • József Baranyi,
  • Bernadette Dora Gombossy de Melo Franco and
  • Nero Luís Augusto

Microbiological testing is an important quality management tool in the food industry. In this study, the hygiene status of beef carcasses sampled in eight Brazilian slaughterhouses was assessed by enumeration of different hygiene indicator microorgan...

  • Article
  • Open Access
13 Citations
5,449 Views
11 Pages

Zika Outbreak Emergency Preparedness and Response of Malaysian Private Healthcare Professionals: Are They Ready?

  • Kingston Rajiah,
  • Mari Kannan Maharajan,
  • Pua Yin Yin,
  • Yap Wei Yee,
  • Wong Wan Lin and
  • Chew Hui Kean

Zika virus has been declared as a public health emergency of international concern. The Center for Disease Control and Prevention has issued guidelines reminding healthcare workers about the importance of taking steps to prevent the spread of Zika vi...

  • Review
  • Open Access
71 Citations
8,486 Views
11 Pages

Vibrio alginolyticus and V. parahaemolyticus, the causative agents of Vibriosis in marine vertebrates and invertebrates, are also responsible for fatal illnesses such as gastroenteritis, septicemia, and necrotizing fasciitis in humans via the ingesti...

  • Review
  • Open Access
322 Citations
30,422 Views
17 Pages

The Production and Delivery of Probiotics: A Review of a Practical Approach

  • Kurt Fenster,
  • Barbara Freeburg,
  • Chris Hollard,
  • Connie Wong,
  • Rune Rønhave Laursen and
  • Arthur C. Ouwehand

To successfully deliver probiotic benefits to the consumer, several criteria must be met. Here, we discuss the often-forgotten challenges in manufacturing the strains and incorporating them in consumer products that provide the required dose at the e...

  • Article
  • Open Access
17 Citations
6,575 Views
22 Pages

Supercoil Levels in E. coli and Salmonella Chromosomes Are Regulated by the C-Terminal 35–38 Amino Acids of GyrA

  • Nikolay S. Rovinskiy,
  • Andrews A. Agbleke,
  • Olga N. Chesnokova and
  • N. Patrick Higgins

Prokaryotes have an essential gene—gyrase—that catalyzes negative supercoiling of plasmid and chromosomal DNA. Negative supercoils influence DNA replication, transcription, homologous recombination, site-specific recombination, genetic tr...

  • Article
  • Open Access
19 Citations
6,472 Views
15 Pages

Variovorax sp. Has an Optimum Cell Density to Fully Function as a Plant Growth Promoter

  • Oyungerel Natsagdorj,
  • Hisayo Sakamoto,
  • Dennis Marvin O. Santiago,
  • Christine D. Santiago,
  • Yoshitake Orikasa,
  • Kazuyuki Okazaki,
  • Seishi Ikeda and
  • Takuji Ohwada

Utilization of plant growth-promoting bacteria colonizing roots is environmentally friendly technology instead of using chemicals in agriculture, and understanding of the effects of their colonization modes in promoting plant growth is important for...

  • Article
  • Open Access
14 Citations
5,081 Views
17 Pages

Vaccination is an effective prevention of influenza infection. However, certain individuals develop a lower antibody response after vaccination, which may lead to susceptibility to subsequent infection. An important challenge in human health is to fi...

  • Article
  • Open Access
84 Citations
7,268 Views
11 Pages

Two bacteria capable of efficiently degrading atrazine were isolated from soil, and named ATLJ-5 and ATLJ-11. ATLJ-5 and ATLJ-11 were identified as Bacillus licheniformis and Bacillus megaterium, respectively. The degradation efficiency of atrazine (...

  • Article
  • Open Access
107 Citations
10,670 Views
10 Pages

Characterization a Novel Butyric Acid-Producing Bacterium Collinsella aerofaciens Subsp. Shenzhenensis Subsp. Nov.

  • Panpan Qin,
  • Yuanqiang Zou,
  • Ying Dai,
  • Guangwen Luo,
  • Xiaowei Zhang and
  • Liang Xiao

Butyrate-producing bacteria can biosynthesize butyrate and alleviate inflammatory diseases. However, few studies have reported that the genus Collinsella has the ability to produce butyric acid. Here, our study depicts a Collinsella strain, which is...

  • Review
  • Open Access
127 Citations
13,177 Views
22 Pages

Previously known as Enterobacter sakazakii from 1980 to 2007, Cronobacter sakazakii is an opportunistic bacterium that survives and persists in dry and low-moisture environments, such as powdered infant formula. Although C. sakazakii causes disease i...

  • Article
  • Open Access
16 Citations
5,421 Views
12 Pages

The consumption of various meats prevalent throughout the world affects host health probably by associating with compositional shifts of gut microbiota. However, the responses of gut microbiota to different types of meat are not well understood. In t...

  • Review
  • Open Access
46 Citations
5,934 Views
10 Pages

Establishment of Listeria monocytogenes in the Gastrointestinal Tract

  • Morgan L. Davis,
  • Steven C. Ricke and
  • Janet R. Donaldson

Listeria monocytogenes is a Gram positive foodborne pathogen that can colonize the gastrointestinal tract of a number of hosts, including humans. These environments contain numerous stressors such as bile, low oxygen and acidic pH, which may impact t...

  • Article
  • Open Access
51 Citations
6,445 Views
18 Pages

Response Surface Methodology Optimization of an Acidic Protease Produced by Penicillium bilaiae Isolate TDPEF30, a Newly Recovered Endophytic Fungus from Healthy Roots of Date Palm Trees (Phoenix dactylifera L.)

  • Fedia Ben Mefteh,
  • Fakher Frikha,
  • Amal Daoud,
  • Ali Chenari Bouket,
  • Lenka Luptakova,
  • Faizah N. Alenezi,
  • Bader S. Al-Anzi,
  • Tomasz Oszako,
  • Neji Gharsallah and
  • Lassaad Belbahri

To explore proteolytic activity of endophytic fungi inhabiting date palm roots, a Penicillium bilaiae isolate, displaying the highest level of protease production, has been recovered. Response surface methodology (RSM) was applied to optimize culture...

  • Article
  • Open Access
57 Citations
9,196 Views
14 Pages

Biofilm Specific Activity: A Measure to Quantify Microbial Biofilm

  • Laura Corte,
  • Debora Casagrande Pierantoni,
  • Carlo Tascini,
  • Luca Roscini and
  • Gianluigi Cardinali

Microbes growing onto solid surfaces form complex 3-D biofilm structures characterized by the production of extracellular polymeric compounds and an increased resistance to drugs. The quantification of biofilm relays currently on a number of differen...

  • Article
  • Open Access
4 Citations
4,876 Views
18 Pages

Urbanization Altered Bacterial and Archaeal Composition in Tidal Freshwater Wetlands Near Washington DC, USA, and Buenos Aires, Argentina

  • Martina Gonzalez Mateu,
  • Cedric Evan Park,
  • Cullen Patrick McAskill,
  • Andrew H. Baldwin and
  • Stephanie A. Yarwood

Urban expansion causes coastal wetland loss, and environmental stressors associated with development can lead to wetland degradation and loss of ecosystem services. This study investigated the effect of urbanization on prokaryotic community compositi...

  • Review
  • Open Access
92 Citations
12,857 Views
16 Pages

Mycobacterium tuberculosis (Mtb) remains an important human pathogen. The Mtb cell envelope is a critical bacterial structure that contributes to virulence and pathogenicity. Mycobacterial membrane protein large (MmpL) proteins export bulky, hydropho...

  • Article
  • Open Access
51 Citations
7,240 Views
14 Pages

Bacillus subtilis DSM 32315 Supplementation Attenuates the Effects of Clostridium perfringens Challenge on the Growth Performance and Intestinal Microbiota of Broiler Chickens

  • Cristiano Bortoluzzi,
  • Bruno Serpa Vieira,
  • Juliano Cesar de Paula Dorigam,
  • Anita Menconi,
  • Adebayo Sokale,
  • Kiran Doranalli and
  • Todd Jay Applegate

The objective of this study was to evaluate the effects of the dietary supplementation of Bacillus subtilis DSM 32315 (probiotic) on the performance and intestinal microbiota of broiler chickens infected with Clostridium perfringens (CP). One-day-old...

  • Article
  • Open Access
5 Citations
4,444 Views
25 Pages

Multiple lines of evidence indicate that CD8 + T cells are important in the control of HIV-1 (HIV) replication. However, CD8 + T cells induced by natural infection cannot eliminate the virus or reduce viral loads to acceptably low lev...

  • Review
  • Open Access
74 Citations
13,093 Views
27 Pages

Microbial Population Changes and Their Relationship with Human Health and Disease

  • Ana Isabel Álvarez-Mercado,
  • Miguel Navarro-Oliveros,
  • Cándido Robles-Sánchez,
  • Julio Plaza-Díaz,
  • María José Sáez-Lara,
  • Sergio Muñoz-Quezada,
  • Luis Fontana and
  • Francisco Abadía-Molina

Specific microbial profiles and changes in intestinal microbiota have been widely demonstrated to be associated with the pathogenesis of a number of extra-intestinal (obesity and metabolic syndrome) and intestinal (inflammatory bowel disease) disease...

  • Review
  • Open Access
121 Citations
15,545 Views
26 Pages

Probiotics and Prebiotics for the Amelioration of Type 1 Diabetes: Present and Future Perspectives

  • Sidharth Mishra,
  • Shaohua Wang,
  • Ravinder Nagpal,
  • Brandi Miller,
  • Ria Singh,
  • Subhash Taraphder and
  • Hariom Yadav

Type 1-diabetes (T1D) is an autoimmune disease characterized by immune-mediated destruction of pancreatic beta (β)-cells. Genetic and environmental interactions play an important role in immune system malfunction by priming an aggressive adaptiv...

  • Brief Report
  • Open Access
10 Citations
5,591 Views
11 Pages

In many countries including Japan, the status of emerging antimicrobial resistance among Serratia spp. and Citrobacter spp. in companion animals remains unknown because these genera are rarely isolated from animals. In this study, 30 Serratia spp. an...

  • Review
  • Open Access
54 Citations
7,599 Views
10 Pages

Modulation of the Immune Response to Improve Health and Reduce Foodborne Pathogens in Poultry

  • Christina L. Swaggerty,
  • Todd R. Callaway,
  • Michael H. Kogut,
  • Andrea Piva and
  • Ester Grilli

Salmonella and Campylobacter are the two leading causes of bacterial-induced foodborne illness in the US. Food production animals including cattle, swine, and chickens are transmission sources for both pathogens. The number of Salmonella outbreaks at...

  • Editorial
  • Open Access
8 Citations
3,367 Views
2 Pages

Heat-loving microorganisms or thermophiles arouse noticeable scientific interest nowadays, not only with the aim to elucidate the mystery of life at high temperatures, but also due to the huge field of biotechnological applications of the enzymes the...

  • Communication
  • Open Access
18 Citations
4,487 Views
9 Pages

Pathogenic mycobacteria are able to persist intracellularly in macrophages, whereas non-pathogenic mycobacteria are effectively combated and eliminated after their phagocytosis. It is known that TGF-β plays an important role in this context. Inf...

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Microorganisms - ISSN 2076-2607