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Vaccines, Volume 10, Issue 11

2022 November - 206 articles

Cover Story: Current SARS-CoV-2 vaccines are administered systemically and result in poor immunogenicity at the mucosa, ultimately failing to prevent infection. We engineered B. subtilis spores to express SARS-CoV-2 antigens and used these to nasally boost a systemic prime consisting of either the rSpike protein or the AZD1222 vaccine. This heterologous systemic prime–mucosal boost strategy evoked mucosal IgA and is potentially protective, as shown in the hamster model of SARS-CoV-2 infection. Coupled with their ease of production, heat stability, and extraordinary resistance properties, spore vaccines, used mucosally, lend themselves to pandemic situations, facilitating a method with which to both augment systemic immunity as well as induce mucosal immunity, a prerequisite for complete protection. Such an approach is likely to have applications in other viral diseases. View this paper
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Articles (206)

  • Article
  • Open Access
6 Citations
2,554 Views
15 Pages

Evaluation of the Oral Microcirculation in Patients Undergoing Anti COVID-19 Vaccination: A Preliminary Study

  • Adriana Acquaro,
  • Giorgia Brusca,
  • Sofia Casella,
  • Enzo Maria Cumbo,
  • Antonio Della Valle,
  • Mohmed Isaqali Karobari,
  • Giuseppe Marino,
  • Anand Marya,
  • Pietro Messina and
  • Cesare Valenti
  • + 3 authors

21 November 2022

Videocapillaroscopy allows the study of both the morphological and architectural structure of the microcirculation and its hemodynamic conditions; these parameters are directly involved in autoimmune and/or inflammatory pathologies. The purpose of th...

  • Article
  • Open Access
14 Citations
5,117 Views
14 Pages

Stakeholder Perspectives of Australia’s National HPV Vaccination Program

  • Caitlin Swift,
  • Aditi Dey,
  • Harunor Rashid,
  • Katrina Clark,
  • Ramesh Manocha,
  • Julia Brotherton and
  • Frank Beard

21 November 2022

Australia has been a world leader in human papillomavirus (HPV) vaccination and was the first country to implement a fully funded national HPV vaccination program, from 2007 for girls and 2013 for boys. In 2018 the program changed from a 4-valent to...

  • Article
  • Open Access
11 Citations
3,853 Views
19 Pages

Allelic Variants of HLA-C Upstream Region, PSORS1C3, MICA, TNFA and Genes Involved in Epidermal Homeostasis and Barrier Function Influence the Clinical Response to Anti-IL-12/IL-23 Treatment of Patients with Psoriasis

  • Martina Morelli,
  • Marco Galluzzo,
  • Claudia Scarponi,
  • Stefania Madonna,
  • Giovanni Luca Scaglione,
  • Giampiero Girolomoni,
  • Marina Talamonti,
  • Luca Bianchi and
  • Cristina Albanesi

21 November 2022

Several biologic therapies have been developed to treat moderate-to-severe psoriasis, with patients exhibiting different clinical benefits, possibly due to the heterogeneity of pathogenic processes underlying their conditions. Ustekinumab targets the...

  • Opinion
  • Open Access
1 Citations
2,765 Views
5 Pages

21 November 2022

The recurrence of the COVID-19 pandemic in 2022 has had a great impact on people’s mentality, although the government has controlled it through a series of effective measures. What is noteworthy is that the public opinion on vaccines has change...

  • Article
  • Open Access
4 Citations
4,550 Views
11 Pages

Freedom of Choice to Vaccinate and COVID-19 Vaccine Hesitancy in Italy

  • Mawulorm K. I. Denu,
  • Alberto Montrond,
  • Rachael Piltch-Loeb,
  • Marco Bonetti,
  • Veronica Toffolutti,
  • Marcia A. Testa and
  • Elena Savoia

21 November 2022

Despite the availability of effective vaccines that lower mortality and morbidity associated with COVID-19, many countries including Italy have adopted strict vaccination policies and mandates to increase the uptake of the COVID-19 vaccine. Such mand...

  • Case Report
  • Open Access
4 Citations
4,254 Views
7 Pages

A Case of Purpura Annularis Telangiectodes of Majocchi after Anti-SARS-CoV-2 Pfizer-BioNTech Vaccine: Is There an Association?

  • Francesca Ambrogio,
  • Carmelo Laface,
  • Giorgia Sbarra,
  • Raffaele Filotico,
  • Girolamo Ranieri,
  • Chiara Barlusconi,
  • Aurora De Marco,
  • Gerardo Cazzato,
  • Domenico Bonamonte and
  • Caterina Foti
  • + 1 author

21 November 2022

The advent of vaccines has drastically reduced the incidence, morbidity, and mortality related to COVID-19, and with the increase in the number of vaccinated subjects, there have been reports of some adverse events, including skin reactions. In this...

  • Article
  • Open Access
52 Citations
3,921 Views
8 Pages

Comparison of Biological, Pharmacological Characteristics, Indications, Contraindications and Adverse Effects of JYNNEOS and ACAM2000 Monkeypox Vaccines

  • Sultan Ayoub Meo,
  • Abeer A. Al-Masri,
  • David C. Klonoff,
  • Abdullah Nasser Alshahrani and
  • Thamir Al-khlaiwi

21 November 2022

Human monkeypox is an emerging viral zoonotic disease, that has caused highly distinctive, challenging and threatening problems worldwide. The US Food and Drug Administration (FDA) has given interim authorization for the JYNNEOS and ACAM2000 vaccines...

  • Article
  • Open Access
7 Citations
4,327 Views
12 Pages

Strengthening the Link between Vaccine Predispositions and Vaccine Advocacy through Certainty

  • Borja Paredes,
  • Miguel A. Martín Cárdaba,
  • Lorena Moreno,
  • Nerea Cano,
  • Pablo Briñol,
  • Ubaldo Cuesta and
  • Richard E. Petty

20 November 2022

Background. Instruments designed to assess individual differences in predispositions towards vaccination are useful in predicting vaccination-related outcomes. Despite their importance, there is relatively little evidence regarding the conditions und...

  • Viewpoint
  • Open Access
11 Citations
4,683 Views
9 Pages

20 November 2022

Genetic variants of vaccine poliovirus type 2, imported from an unknown source, were detected in waste waters in Jerusalem, London and New York in early 2022. Wild poliovirus type 2 was globally eradicated in 1999, but vaccine virus type 2 continued...

  • Article
  • Open Access
16 Citations
2,964 Views
17 Pages

Understanding Influenza and SARS-CoV-2 Vaccine Hesitancy in Racial and Ethnic Minority Caregivers

  • Shannon H. Baumer-Mouradian,
  • Rebecca J. Hart,
  • Alexis Visotcky,
  • Raphael Fraser,
  • Swathi Prasad,
  • Michael Levas,
  • Mark Nimmer and
  • David C. Brousseau

20 November 2022

(1) Background: We compared influenza and SARS-CoV-2 vaccine hesitancy levels in Black, Hispanic, and White parents/caregivers and identified barriers and facilitators to vaccine acceptance. (2) Methods: This was a mixed methods study. A cross-sectio...

  • Article
  • Open Access
7 Citations
2,962 Views
10 Pages

Impact of COVID-19 Vaccination on Seroprevalence of SARS-CoV-2 among the Health Care Workers in a Tertiary Care Centre, South India

  • Divyaa Elangovan,
  • Shifa Meharaj Shaik Hussain,
  • Somasunder Virudhunagar Muthuprakash,
  • Nanthini Devi Periadurai,
  • Ashok Viswanath Nalankilli,
  • Harshada Volvoikar,
  • Preethy Ramani,
  • Jayanthi Sivasubramaniam,
  • Kalyani Mohanram and
  • Krishna Mohan Surapaneni

19 November 2022

Global vaccine development efforts have been accelerated in response to the devastating COVID-19 pandemic. The study aims to determine the seroprevalence of SARS-CoV-2 IgG antibodies among vaccine-naïve healthcare workers and to describe the imp...

  • Viewpoint
  • Open Access
2 Citations
3,765 Views
18 Pages

A Reflection of Metabolic Syndrome through the Window of COVID-19

  • Liam Pock Ho,
  • Chuen Wen Tan,
  • Heng Joo Ng,
  • Wai Mun Jason Chay,
  • Jing Yuan Tan and
  • Su Yen Goh

19 November 2022

COVID-19 and metabolic syndrome, though seemingly different disorders, appear to share certain common pathogenic components, especially in the development of COVID-19-associated diabetes mellitus. The similarities include impairment in immunoendothel...

  • Review
  • Open Access
13 Citations
4,781 Views
36 Pages

Advances in the Lung Cancer Immunotherapy Approaches

  • Hafiza Padinharayil,
  • Reema Rose Alappat,
  • Liji Maria Joy,
  • Kavya V. Anilkumar,
  • Cornelia M. Wilson,
  • Alex George,
  • Abilash Valsala Gopalakrishnan,
  • Harishkumar Madhyastha,
  • Thiyagarajan Ramesh and
  • Raja Ganesan
  • + 2 authors

19 November 2022

Despite the progress in the comprehension of LC progression, risk, immunologic control, and treatment choices, it is still the primary cause of cancer-related death. LC cells possess a very low and heterogeneous antigenicity, which allows them to pas...

  • Review
  • Open Access
22 Citations
3,318 Views
9 Pages

COVID-19 Vaccination in Migrants and Refugees: Lessons Learnt and Good Practices

  • Palmira Immordino,
  • Davide Graci,
  • Alessandra Casuccio,
  • Vincenzo Restivo and
  • Walter Mazzucco

19 November 2022

The COVID-19 pandemic has exacerbated inequalities between low- and high-income countries. Within the latter, a greater impact is seen in the poorest and most vulnerable people, including refugees, asylum seekers, and migrants. They all may experienc...

  • Article
  • Open Access
4 Citations
3,138 Views
17 Pages

30-Minute Highly Multiplexed VaxArray Immunoassay for Pneumococcal Vaccine Antigen Characterization

  • Tianjing Hu,
  • David F. Miller,
  • Amber W. Taylor,
  • Christine Riley,
  • Caitlin McCormick,
  • Keely N. Thomas,
  • Rachel Y. Gao,
  • Kathy L. Rowlen,
  • Emilia B. Byrne and
  • Erica D. Dawson
  • + 2 authors

19 November 2022

Pneumonia accounts for over 20% of deaths worldwide in children aged 1 to 5 years, disproportionately affecting lower- and middle-income countries. Effective, highly multivalent pneumococcal vaccines are available to decrease disease burden, with num...

  • Article
  • Open Access
13 Citations
3,764 Views
11 Pages

Differential Cell Line Susceptibility to the SARS-CoV-2 Omicron BA.1.1 Variant of Concern

  • Hitesh Dighe,
  • Prasad Sarkale,
  • Deepak Y. Patil,
  • Sreelekshmy Mohandas,
  • Anita M. Shete,
  • Rima R. Sahay,
  • Rajen Lakra,
  • Savita Patil,
  • Triparna Majumdar and
  • Pragya D. Yadav
  • + 3 authors

18 November 2022

The unique mutations of the SARS-CoV-2 Omicron variant are associated with increased transmissibility, immune escape, increased binding affinity to ACE-2, and increased viral load. Omicron exhibited a shift in tropism infecting the upper respiratory...

  • Article
  • Open Access
7 Citations
3,021 Views
10 Pages

Plant-Produced S1 Subunit Protein of SARS-CoV-2 Elicits Immunogenic Responses in Mice

  • Chalisa Panapitakkul,
  • Narach Khorattanakulchai,
  • Kaewta Rattanapisit,
  • Theerakarn Srisangsung,
  • Balamurugan Shanmugaraj,
  • Supranee Buranapraditkun,
  • Chutitorn Ketloy,
  • Eakachai Prompetchara and
  • Waranyoo Phoolcharoen

18 November 2022

SARS-CoV-2 is responsible for the ongoing COVID-19 pandemic. The virus spreads rapidly with a high transmission rate among humans, and hence virus management has been challenging owing to finding specific therapies or vaccinations. Hence, an effectiv...

  • Article
  • Open Access
6 Citations
2,404 Views
14 Pages

Bursal-Derived BP7 Induces the miRNA Molecular Basis of Chicken Macrophages and Promotes the Differentiation of B Cells

  • Jiaxi Cai,
  • Ze Zhang,
  • Chenfei Li,
  • Shanshan Hao,
  • Anran Lu,
  • Xiangyu Huang and
  • Xiuli Feng

18 November 2022

The bursa of Fabricius (BF) is a vital central humoral immune organ unique to birds. The bioactive peptide BP7 derived from bursa is reported to promote the vaccine immune response and antibody production. However, the regulatory effect on antigen pr...

  • Article
  • Open Access
7 Citations
2,667 Views
12 Pages

Clinical Presentation of COVID-19 and Antibody Responses in Bangladeshi Patients Infected with the Delta or Omicron Variants of SARS-CoV-2

  • Asish Kumar Ghosh,
  • Olfert Landt,
  • Mahmuda Yeasmin,
  • Mohiuddin Sharif,
  • Rifat Hossain Ratul,
  • Maruf Ahmed Molla,
  • Tasnim Nafisa,
  • Mymuna Binte Mosaddeque,
  • Nur Hosen and
  • Simon D. Lytton
  • + 6 authors

18 November 2022

The clinical presentation of COVID-19 and the specific antibody responses associated with SARS-CoV-2 variants have not been investigated during the emergence of Omicron variants in Bangladesh. The Delta and Omicron variants were identified by post-PC...

  • Article
  • Open Access
25 Citations
3,919 Views
13 Pages

18 November 2022

Vaccination hesitancy (VH) is an important public health issue. The determinants of parental decisions on whether to vaccinate their children are multidimensional and need to be carefully considered in the COVID-19 era. Our study aims to investigate...

  • Article
  • Open Access
3 Citations
2,361 Views
8 Pages

Parental Attitudes and Perceptions of Support after Brief Clinician Intervention Predict Intentions to Accept the Adjuvanted Seasonal Influenza Vaccination: Findings from the Pediatric Influenza Vaccination Optimization Trial (PIVOT)–I

  • William A. Fisher,
  • Vladimir Gilca,
  • Michelle Murti,
  • Alison Orth,
  • Hartley Garfield,
  • Paul Roumeliotis,
  • Emmanouil Rampakakis,
  • Vivien Brown,
  • John Yaremko and
  • James A. Mansi
  • + 2 authors

18 November 2022

Adjuvanted trivalent influenza vaccine (aTIV) provides enhanced protection against seasonal influenza in children compared with nonadjuvanted trivalent influenza vaccine (TIV). This prospective cohort study assessed parental attitudes, beliefs, and i...

  • Article
  • Open Access
8 Citations
3,083 Views
10 Pages

18 November 2022

Measles and varicella still occur in the general population despite the widespread vaccination against them, and healthcare workers (HCWs) are still at risk of exposure to these diseases. Here, we evaluated the seroprevalence of measles and varicella...

  • Article
  • Open Access
1 Citations
2,057 Views
6 Pages

Clinicians Are Not Able to Infer Parental Intentions to Vaccinate Infants with a Seasonal Influenza Vaccine, and Perhaps They Should Not Try: Findings from the Pediatric Influenza Vaccination Optimization Trial (PIVOT)–IV

  • William A. Fisher,
  • Vladimir Gilca,
  • Michelle Murti,
  • Alison Orth,
  • Hartley Garfield,
  • Paul Roumeliotis,
  • Emmanouil Rampakakis,
  • Vivien Brown,
  • John Yaremko and
  • James A. Mansi
  • + 2 authors

18 November 2022

This prospective cohort survey evaluated the concordance of clinicians’ perceptions of parental intentions and parents’ actual intentions to vaccinate their infants against influenza. During a routine healthy baby visit, clinicians provid...

  • Article
  • Open Access
4 Citations
3,242 Views
12 Pages

Real-World Immunogenicity and Reactogenicity of Two Doses of Pfizer-BioNTech COVID-19 Vaccination in Children Aged 5–11 Years

  • Gili Joseph,
  • Elisheva Klein,
  • Yaniv Lustig,
  • Yael Weiss-Ottolenghi,
  • Keren Asraf,
  • Victoria Indenbaum,
  • Sharon Amit,
  • Or Kriger,
  • Mayan Gilboa and
  • Michal Stein
  • + 4 authors

18 November 2022

There are limited data concerning the immunogenicity and reactogenicity of COVID-19 vaccines in children. A total of 110 children, 5–11 years old were vaccinated with two doses (with a 3-week interval between doses) of the Pfizer-BioNTech COVID...

  • Communication
  • Open Access
4 Citations
2,282 Views
10 Pages

Determining the SARS-CoV-2 Anti-Spike Cutoff Level Denoting Neutralizing Activity Using Two Commercial Kits

  • Engy Mohamed El-Ghitany,
  • Mona H. Hashish,
  • Azza Galal Farghaly and
  • Eman A. Omran

18 November 2022

Background: The viral neutralization assay is the gold standard to estimate the level of immunity against SARS-CoV-2. This study analyzes the correlation between the quantitative Anti-SARS-CoV-2 QuantiVac ELISA (IgG) and the NeutraLISA neutralization...

  • Review
  • Open Access
12 Citations
5,370 Views
16 Pages

Protecting the Offspring, the Gift of Maternal Immunization: Current Status and Future Perspectives

  • Theano Lagousi,
  • Despoina Gkentzi,
  • Maria Geropeppa,
  • Panagiota Tsagkli and
  • Vana Spoulou

18 November 2022

Pregnancy is characterized by immunological alterations in pregnant women that permit the growth of a semi-allogenic fetus, resulting in greater susceptibility of childbearing women to infections. Furthermore, due to the immaturity of the immune syst...

  • Article
  • Open Access
7 Citations
3,566 Views
11 Pages

Subnational Gender Inequality and Childhood Immunization: An Ecological Analysis of the Subnational Gender Development Index and DTP Coverage Outcomes across 57 Countries

  • Nicole E. Johns,
  • Katherine Kirkby,
  • Tracey S. Goodman,
  • Shirin Heidari,
  • Jean Munro,
  • Stephanie Shendale and
  • Ahmad Reza Hosseinpoor

18 November 2022

The role of gender inequality in childhood immunization is an emerging area of focus for global efforts to improve immunization coverage and equity. Recent studies have examined the relationship between gender inequality and childhood immunization at...

  • Case Report
  • Open Access
5 Citations
6,777 Views
10 Pages

Portal Vein and Mesenteric Artery Thrombosis Following the Administration of an Ad26.COV2-S Vaccine—First Case from Romania: A Case Report

  • Florin Savulescu,
  • Cristian Cirlan,
  • Madalina Ionela Iordache-Petrescu,
  • Mihai Iordache,
  • Alexandra Bianca Petrescu and
  • Cristian Blajut

18 November 2022

COVID-19 has significantly affected public health, social life, and economies worldwide. The only effective way to combat the pandemic is through vaccines. Although the vaccines have been in use for some time, safety concerns have still been raised....

  • Review
  • Open Access
6 Citations
4,332 Views
10 Pages

Insight into Prevention of Neisseria Gonorrhoeae: A Short Review

  • Vincenza La Fauci,
  • Daniela Lo Giudice,
  • Raffaele Squeri and
  • Cristina Genovese

18 November 2022

Neisseria gonorrhoeae (gonococcus) and Neisseria meningitidis (meningococcus) are important global pathogens which cause the sexually transmitted diseases gonorrhea and meningitis, respectively, as well as sepsis. We prepared a review according to th...

  • Article
  • Open Access
7 Citations
2,297 Views
12 Pages

Kinetics of Humoral Immunity against SARS-CoV-2 in Healthcare Workers after the Third Dose of BNT162b2 mRNA Vaccine

  • Tiziana Grassi,
  • Giambattista Lobreglio,
  • Alessandra Panico,
  • Chiara Rosato,
  • Antonella Zizza,
  • Roberta Lazzari,
  • Michele Chicone,
  • Floriano Indino and
  • Francesco Bagordo

17 November 2022

Protection provided by COVID-19 vaccines is compromised due to waning immunity over time. This study aimed to assess the level of antibodies anti-S-RBD of SARS-CoV-2 in a cohort of healthcare workers before and, on average, one and four months after...

  • Article
  • Open Access
5 Citations
2,870 Views
12 Pages

17 November 2022

Education and highbrow cultural participation—two dimensions of cultural capital—have previously been identified as determinants of vaccine attitudes, though the links have been mainly inconsistent across studies. The present quantitative...

  • Review
  • Open Access
205 Citations
15,067 Views
42 Pages

Nanoparticle-Based Delivery Systems for Vaccines

  • Rajashri Bezbaruah,
  • Vivek P. Chavda,
  • Lawandashisha Nongrang,
  • Shahnaz Alom,
  • Kangkan Deka,
  • Tutumoni Kalita,
  • Farak Ali,
  • Bedanta Bhattacharjee and
  • Lalitkumar Vora

17 November 2022

Vaccination is still the most cost-effective way to combat infectious illnesses. Conventional vaccinations may have low immunogenicity and, in most situations, only provide partial protection. A new class of nanoparticle-based vaccinations has shown...

  • Article
  • Open Access
5 Citations
2,580 Views
12 Pages

Knowledge, Attitude and Practice towards the COVID-19 Pandemic: A Cross-Sectional Survey Study among the General Public in the Kingdom of Saudi Arabia

  • Namdeo Prabhu,
  • Meshal Aber Alonazi,
  • Hmoud Ali Algarni,
  • Rakhi Issrani,
  • Sarah Hatab Alanazi,
  • Mohammed Katib Alruwaili,
  • Gharam Radhi Alanazi,
  • Azhar Iqbal and
  • Osama Khattak

17 November 2022

Background: The novel coronavirus disease 2019 (COVID-19) is an infectious disease that has been spreading worldwide in an unprecedented manner. The knowledge, attitude and practices of the general population play a vital role in prevention of COVID-...

  • Article
  • Open Access
6 Citations
2,670 Views
12 Pages

17 November 2022

Background. Monitoring of SARS-COV-2 vaccine hesitancy is important for epidemic control. We measured vaccine hesitancy among healthy adults and adults with chronic diseases after they had been offered the first dose of the vaccine in Mexico City. Me...

  • Review
  • Open Access
23 Citations
12,417 Views
17 Pages

The Vaccine World of COVID-19: India’s Contribution

  • Vivek P. Chavda,
  • Disha R. Vihol,
  • Hetvi K. Solanki and
  • Vasso Apostolopoulos

17 November 2022

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) eruption has left not only illness and mortality in its wake, but also an overwhelming threat to health policy, human regality, food security, and struggle worldwide. The accessibility...

  • Review
  • Open Access
30 Citations
6,238 Views
18 Pages

17 November 2022

Electroporation is the process of instantaneously increasing the permeability of a cell membrane under a pulsed electric field. Depending on the parameters of the electric pulses and the target cell electrophysiological characteristics, electroporati...

  • Article
  • Open Access
28 Citations
3,908 Views
19 Pages

17 November 2022

The purpose of the study was to investigate the effects of Eimeria tenella infection on the cecal microbiome, the protein concentration of cecal content, cecal mucosal immunity, and serum endotoxin levels in broilers. Three hundred sixty 14-day-old b...

  • Review
  • Open Access
14 Citations
10,460 Views
22 Pages

Preparedness for the Dengue Epidemic: Vaccine as a Viable Approach

  • Md. Zeyaullah,
  • Khursheed Muzammil,
  • Abdullah M. AlShahrani,
  • Nida Khan,
  • Irfan Ahmad,
  • Md. Shane Alam,
  • Razi Ahmad and
  • Wajihul H. Khan

17 November 2022

Dengue fever is one of the significant fatal mosquito-borne viral diseases and is considered to be a worldwide problem. Aedes mosquito is responsible for transmitting various serotypes of dengue viruses to humans. Dengue incidence has developed promi...

  • Article
  • Open Access
4 Citations
4,381 Views
19 Pages

16 November 2022

Chikungunya virus (CHIKV) re-emergence in the last decade has resulted in explosive epidemics. Along with the classical symptoms of fever and debilitating arthralgia, there were occurrences of unusual clinical presentations such as neurovirulence and...

  • Article
  • Open Access
4 Citations
5,038 Views
11 Pages

Does Measles, Mumps, and Rubella (MMR) Vaccination Protect against COVID-19 Outcomes: A Nationwide Cohort Study

  • Epiphane Kolla,
  • Alain Weill,
  • David Desplas,
  • Laura Semenzato,
  • Mahmoud Zureik and
  • Lamiae Grimaldi

16 November 2022

Cross-protection from previous live attenuated vaccines is proposed to explain the low impact of COVID-19 on children. This study aimed to evaluate the effect of live attenuated MMR vaccines on the risk of being hospitalized for COVID-19 in children....

  • Systematic Review
  • Open Access
35 Citations
4,554 Views
12 Pages

A Systematic Review on Vaccine Hesitancy in Black Communities in Canada: Critical Issues and Research Failures

  • Jude Mary Cénat,
  • Pari-Gole Noorishad,
  • Schwab Mulopo Bakombo,
  • Olivia Onesi,
  • Aya Mesbahi,
  • Wina Paul Darius,
  • Lisa Caulley,
  • Sanni Yaya,
  • Marie-Hélène Chomienne and
  • Patrick R. Labelle
  • + 4 authors

15 November 2022

Black communities have been disproportionately impacted by Coronavirus Disease 2019 (COVID-19) in Canada, in terms of both number of infections and mortality rates. Yet, according to early studies, vaccine hesitancy appears to be higher in Black comm...

  • Systematic Review
  • Open Access
5 Citations
2,918 Views
21 Pages

15 November 2022

Foodborne enteritis is a major disease burden globally. Two of the most common causative bacterial enteropathogens in humans are Campylobacter and Salmonella species which are strongly associated with the consumption of raw or contaminated chicken. T...

  • Article
  • Open Access
9 Citations
3,313 Views
22 Pages

Single-Shot ChAd3-MARV Vaccine in Modified Formulation Buffer Shows 100% Protection of NHPs

  • Courtney L. Finch,
  • Thomas H. King,
  • Kendra J. Alfson,
  • Katie A. Albanese,
  • Julianne N. P. Smith,
  • Paul Smock,
  • Jocelyn Jakubik,
  • Yenny Goez-Gazi,
  • Michal Gazi and
  • Rong Xu
  • + 9 authors

15 November 2022

Marburg virus (MARV) is a virus of high human consequence with a case fatality rate of 24–88%. The global health and national security risks posed by Marburg virus disease (MVD) underscore the compelling need for a prophylactic vaccine, but no...

  • Review
  • Open Access
35 Citations
6,158 Views
23 Pages

Persisting Vaccine Hesitancy in Africa: The Whys, Global Public Health Consequences and Ways-Out—COVID-19 Vaccination Acceptance Rates as Case-in-Point

  • Emmanuel O. Njoga,
  • Olajoju J. Awoyomi,
  • Onyinye S. Onwumere-Idolor,
  • Priscilla O. Awoyomi,
  • Iniobong C. I. Ugochukwu and
  • Stella N. Ozioko

15 November 2022

Vaccine hesitancy (VH) is the seventh among the WHO’s top 10 threats to global public health, which has continued to perpetuate the transmission of vaccine preventable diseases (VPDs) in Africa. Consequently, this paper systematically reviewed...

  • Article
  • Open Access
12 Citations
3,677 Views
9 Pages

15 November 2022

Background: The increase in the coronavirus disease 2019 (COVID-19) vaccination rates in Turkey and in the world plays a key role in reducing the number of deaths and cases from COVID-19. Investigating the underlying causes of COVID-19 vaccine hesita...

  • Review
  • Open Access
9 Citations
8,121 Views
12 Pages

15 November 2022

Although parental vaccines offer long-term protection against homologous strains, they rely exclusively on adaptive immune memory to produce neutralizing antibodies that are ineffective against emerging viral variants. Growing evidence highlights the...

  • Article
  • Open Access
1 Citations
2,222 Views
12 Pages

Long-Term CD4+ T-Cell and Immunoglobulin G Immune Responses in Oncology Workers following COVID-19 Vaccination: An Interim Analysis of a Prospective Cohort Study

  • Corey Gallen,
  • Christopher W. Dukes,
  • Amy Aldrich,
  • Lauren Macaisa,
  • Qianxing Mo,
  • Christopher L. Cubitt,
  • Shari Pilon-Thomas,
  • Anna R. Giuliano,
  • Brian J. Czerniecki and
  • Ricardo L. B. Costa

15 November 2022

We conducted a prospective study to evaluate immune responses to SARS-CoV-2 in oncology workers in which we collected blood and clinical data every 6 months. Spike-specific CD4+ T-cells and immunoglobulin G responses were measured using interferon-ga...

  • Article
  • Open Access
11 Citations
3,878 Views
17 Pages

Perceptions of COVID-19 Maternal Vaccination among Pregnant Women and Healthcare Workers and Factors That Influence Vaccine Acceptance: A Cross-Sectional Study in Barcelona, Spain

  • Elena Marbán-Castro,
  • Ivana Nedic,
  • Mara Ferrari,
  • Esther Crespo-Mirasol,
  • Laia Ferrer,
  • Berta Noya,
  • Anna Marin,
  • Victoria Fumadó,
  • Marta López and
  • Azucena Bardají
  • + 4 authors

15 November 2022

COVID-19 is associated with poor maternal and pregnancy outcomes. COVID-19 vaccination is recommended in Spain, yet vaccination rates in pregnancy are suboptimal. This study investigates the perceptions of pregnant women and healthcare workers (HCW)...

  • Brief Report
  • Open Access
18 Citations
5,398 Views
9 Pages

15 November 2022

This study analyzed perceptions of Indians regarding COVID-19 booster dose vaccines using natural language processing techniques, particularly, sentiment analysis and topic modeling. We analyzed tweets generated by Indian citizens for this study. In...

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Vaccines - ISSN 2076-393X