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Journal of Clinical Medicine, Volume 11, Issue 19

October-1 2022 - 485 articles

Cover Story: The transsphenoidal approach is a common method in the surgical treatment of many pituitary lesions. Due to the limited line of sight, surgical orientation can be difficult, e.g., in cases of anatomical variants, small intercarotid artery distances and previous transsphenoidal surgery. Neuronavigation, and especially the enhancement of (augmented reality) the pure microscope view with additional anatomical information, such as tumor outlines or risk structures, provided by integrated head up displays, can greatly and reliably facilitate surgical orientation and increase surgical comfort and patient safety and might also assist in the training of less-experienced surgeons to become more familiar with surgical orientation and strategies in the narrow space provided by the speculum in the transsphenoidal approach. View this paper
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Articles (485)

  • Article
  • Open Access
3 Citations
2,691 Views
15 Pages

An Intermodal Correlation Study among Imaging, Histology, Procedural and Clinical Parameters in Cerebral Thrombi Retrieved from Anterior Circulation Ischemic Stroke Patients

  • Rebeka Viltužnik,
  • Franci Bajd,
  • Zoran Miloševič,
  • Igor Kocijančič,
  • Miran Jeromel,
  • Andrej Fabjan,
  • Eduard Kralj,
  • Jernej Vidmar and
  • Igor Serša

10 October 2022

The precise characterization of cerebral thrombi prior to an interventional procedure can ease the procedure and increase its success. This study investigates how well cerebral thrombi can be characterized by computed tomography (CT), magnetic resona...

  • Article
  • Open Access
5 Citations
3,570 Views
16 Pages

Exploring the Complex Network of Heme-Triggered Effects on the Blood Coagulation System

  • Sarah Mubeen,
  • Daniel Domingo-Fernández,
  • Sara Díaz del Ser,
  • Dhwani M. Solanki,
  • Alpha T. Kodamullil,
  • Martin Hofmann-Apitius,
  • Marie-T. Hopp and
  • Diana Imhof

10 October 2022

Excess labile heme, occurring under hemolytic conditions, displays a versatile modulator in the blood coagulation system. As such, heme provokes prothrombotic states, either by binding to plasma proteins or through interaction with participating cell...

  • Article
  • Open Access
3 Citations
2,793 Views
16 Pages

Age- and Severity-Associated Humoral Immunity Response in COVID-19 Patients: A Cohort Study from Wuhan, China

  • An Zhu,
  • Min Liu,
  • Yang Li,
  • Qing Lei,
  • Qiaoyi Wu,
  • Mingxi Lin,
  • Danyun Lai,
  • Linfang Lu,
  • Siqi Yu and
  • Shujuan Guo
  • + 15 authors

10 October 2022

Age has been found to be the single most significant factor in COVID-19 severity and outcome. However, the age-related severity factors of COVID-19 have not been definitively established. In this study, we detected SARS-CoV-2-specific antibody respon...

  • Article
  • Open Access
1 Citations
4,680 Views
9 Pages

Is Primary Bone Marrow Edema of the Knee Associated with Thyroid Disorders? A Retrospective Clinical Study

  • Luca De Berardinis,
  • Fjorela Qordja,
  • Luca Farinelli,
  • Andrea Faragalli,
  • Rosaria Gesuita and
  • Antonio Pompilio Gigante

10 October 2022

Primary bone marrow edema (BME) of the knee is still an elusive condition. This retrospective study was undertaken to gain insight into its characteristic features. The records of 48 patients with primary BME of the knee diagnosed by magnetic resonan...

  • Article
  • Open Access
4 Citations
2,107 Views
9 Pages

The Development of Electroretinographic Oscillatory Potentials in Healthy Young Children

  • Ting Zhang,
  • Jinglin Lu,
  • Zhaoxin Jiang,
  • Li Huang,
  • Jun Zeng,
  • Liming Cao,
  • Xiaoling Luo,
  • Bilin Yu and
  • Xiaoyan Ding

10 October 2022

Purpose: This study aimed to summarize the electroretinographic oscillatory potential (OP) responses in healthy young children recorded by RETeval. Methods: By using the RETeval system, we recorded the implicit times and amplitudes of the OPs (OP1-5)...

  • Article
  • Open Access
6 Citations
2,664 Views
13 Pages

How Satisfied Are Women 6 Months after a Pessary Fitting for Pelvic Organ Prolapse?

  • Siegfried Nebel,
  • Christian Creveuil,
  • Michel Briex,
  • Raffaèle Fauvet,
  • Anne Villot and
  • Anne-Cécile Pizzoferrato

10 October 2022

Background: The non-surgical solution for Pelvic Organ Prolapse (POP) typically consists of a pessary fitting. We aimed to assess patient satisfaction and symptom improvement 6 months after a pessary fitting and to identify risk factors associated wi...

  • Article
  • Open Access
6 Citations
2,141 Views
10 Pages

10 October 2022

Neutrophil gelatinase-associated lipocalin (NGAL) has been proposed as an early marker for estimating the risk of contrast-induced acute kidney injury (CI-AKI). However, the predictive value of baseline serum NGAL levels for CI-AKI remains unclear. S...

  • Article
  • Open Access
2,144 Views
10 Pages

Switching Antipsychotic Medications in People with Schizophrenia: A 4-Year Naturalistic Study

  • Giammarco Cascino,
  • Rossella Ceres,
  • Alessio Maria Monteleone,
  • Paola Bucci,
  • Giulia Maria Giordano,
  • Silvana Galderisi and
  • Palmiero Monteleone

10 October 2022

Although generally effective in ameliorating the core manifestations of schizophrenia, antipsychotics (APs) may lead to only suboptimal responses or may be associated with a variety of treatment-related adverse events which require additional treatme...

  • Article
  • Open Access
2,138 Views
12 Pages

Nonalcoholic Steatohepatitis: A 9-Year Follow Up Cohort Study

  • Alessandra Mangia,
  • Annarita Valeria Piazzolla,
  • Maria Maddalena Squillante,
  • Giovanna Cocomazzi,
  • Vanna Maria Valori,
  • Massimiliano Copetti,
  • Paola Parente,
  • Vito Attino and
  • Maria Guido

10 October 2022

Background and aim: Non-alcoholic fatty liver disease (NAFLD) may progress to severe liver fibrosis and cirrhosis. A limited number of studies with a long follow up assessed fibrosis progression and related predictors in untreated patients with a his...

  • Review
  • Open Access
18 Citations
5,978 Views
14 Pages

Long-Term Management of Pulmonary Embolism: A Review of Consequences, Treatment, and Rehabilitation

  • Anette Arbjerg Højen,
  • Peter Brønnum Nielsen,
  • Thure Filskov Overvad,
  • Ida Ehlers Albertsen,
  • Frederikus A. Klok,
  • Nanna Rolving,
  • Mette Søgaard and
  • Anne Gulbech Ording

10 October 2022

The concept of pulmonary embolism is evolving. Recent and emerging evidence on the treatment of specific patient populations, its secondary prevention, long-term complications, and the unmet need for rehabilitation has the potential to change clinica...

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J. Clin. Med. - ISSN 2077-0383Creative Common CC BY license