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Veterinary Sciences, Volume 6, Issue 4

2019 December - 29 articles

Cover Story: Our group has discovered and developed a surface antigen for Mycobacterium avium subspecies paratuberculosis (Map), the bacterium that causes Johne's disease (JD). This antigen, termed an ethanol extract, has shown strong potential for use in a diagnostic test for JD. The problem is that the antigen has a complex makeup consisting of lipid, carbohydrate, and proteins, and thus, it would be beneficial to determine more precisely what these components are and if they are necessary for the antigenicity of diagnostic tests. We discovered that it is the carbohydrate component and not the proteins that are antigenic. We further defined what some of these components are within the extract. This new knowledge should enable researchers to engineer or refine this antigen using only the most immunogenic components to improve diagnostic tests. View this paper
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Articles (29)

  • Article
  • Open Access
10 Citations
6,787 Views
8 Pages

Clove Oil Delays Rather Than Prevents Scur/Horn Growth in Dairy Cattle

  • Mhairi Sutherland,
  • Alan Julian and
  • Frances Huddart

13 December 2019

The objective of this study was to evaluate if administration of clove oil prevents scur/horn growth in dairy cattle long term. At approximately 4 days of age, calves had one of four treatments assigned to each horn bud: (1) clove oil administered su...

  • Case Report
  • Open Access
6 Citations
13,114 Views
20 Pages

13 December 2019

Superficial corneal ulcers that fail to heal within a normal time period and are refractory to conventional therapy in dogs are common in veterinary practice. Different etiologies can lead to this result, including spontaneous chronic corneal epithel...

  • Article
  • Open Access
7 Citations
4,674 Views
11 Pages

Connexin 26 and Connexin 43 in Canine Mammary Carcinoma

  • Savannah Luu,
  • Cynthia Bell,
  • Sarah Schneider and
  • Thu Annelise Nguyen

9 December 2019

Incidence of canine mammary carcinoma is two times higher than the rate of human breast cancer. Mammary tumors are the most common type of cancer in intact female dogs and account for about half of all neoplasms in these dogs. Well-established models...

  • Article
  • Open Access
2 Citations
5,364 Views
7 Pages

Treatment of Harvest Mite Infestation in Dogs Using a Permethrin 54.5% and Fipronil 6.1% (Effitix®) Topical Spot-On Formulation

  • Line-Alice Lecru,
  • Daniel Combarros,
  • Eloy Castilla-Castaño,
  • Christelle Navarro and
  • Marie Christine Cadiergues

7 December 2019

Background—The study aims to assess the efficacy of a permethrin 54.5%-fipronil 6.1%-based spot-on solution in dogs naturally infested with Neotrombicula in an open-label controlled study. Methods—Ten naturally infested dogs received one drop per aff...

  • Article
  • Open Access
20 Citations
5,208 Views
12 Pages

A Long-Term Study of the Biological Properties of ASF Virus Isolates Originating from Various Regions of the Russian Federation in 2013–2018

  • Andrei Pershin,
  • Ivan Shevchenko,
  • Alexey Igolkin,
  • Ivan Zhukov,
  • Ali Mazloum,
  • Elena Aronova,
  • Natalia Vlasova and
  • Alexander Shevtsov

6 December 2019

Biological properties of the African swine fever (ASF) virus isolates originating from various regions of the Russian Federation (2013–2018) were studied in a series of experimental infections. Comparative analysis allowed us to establish the d...

  • Article
  • Open Access
6 Citations
5,249 Views
13 Pages

30 November 2019

The single intradermal comparative cervical tuberculin (SICCT) test is the primary test for ante-mortem diagnosis of bovine tuberculosis (TB) in England and Wales. When an animal is first classified as an inconclusive reactor (IR) using this test, it...

  • Article
  • Open Access
6 Citations
4,658 Views
12 Pages

Transcriptional Profiles of Murine Bone Marrow-Derived Dendritic Cells in Response to Peste des Petits Ruminants Virus

  • Lingxia Li,
  • Jinyan Wu,
  • Dan Liu,
  • Guoyu Du,
  • Yongsheng Liu,
  • Youjun Shang and
  • Xiangtao Liu

29 November 2019

Background: Peste des petits ruminants virus (PPRV) is the causative agent of PPR, which can cause an acute, highly contagious and fatal disease of sheep and goats, resulting in significant economic losses for commercial animal husbandry due to its h...

  • Article
  • Open Access
6 Citations
5,356 Views
13 Pages

Mycobacterium avium Subspecies paratuberculosis DNA and Antibodies in Dairy Goat Colostrum and Milk

  • Karianne Lievaart-Peterson,
  • Saskia Luttikholt,
  • Maaike Gonggrijp,
  • Robin Ruuls,
  • Lars Ravesloot and
  • Ad P. Koets

29 November 2019

Mycobacterium avium subspecies paratuberculosis (MAP) is endemic in the Dutch dairy goat population causing economic loss, and negatively influencing welfare. Moreover, there are concerns about a potential zoonotic risk. Therefore the industry’...

  • Feature Paper
  • Case Report
  • Open Access
49 Citations
8,503 Views
9 Pages

African Swine Fever in a Bulgarian Backyard Farm—A Case Report

  • Laura Zani,
  • Klaas Dietze,
  • Zlatina Dimova,
  • Jan Hendrik Forth,
  • Daniel Denev,
  • Klaus Depner and
  • Tsviatko Alexandrov

21 November 2019

African swine fever (ASF) is one of the most threatening diseases for the pig farming sector worldwide. As an effective vaccine is lacking, strict application of control measures is the only way to fight the disease in both industrial farms and backy...

  • Article
  • Open Access
21 Citations
7,240 Views
14 Pages

Detection and Molecular Characterization of a Natural Coinfection of Marek’s Disease Virus and Reticuloendotheliosis Virus in Brazilian Backyard Chicken Flock

  • Ruy D. Chacón,
  • Claudete S. Astolfi-Ferreira,
  • Marta B. Guimarães,
  • Luciana N. Torres,
  • David I. De la Torre,
  • Lilian R. M. de Sá and
  • Antonio J. Piantino Ferreira

20 November 2019

Marek’s disease virus (MDV) and the reticuloendotheliosis virus (REV) are two of the primary oncogenic viruses that significantly affect chickens. In Brazil, there have been no previous published reports on the presence of field REV alone or in...

  • Article
  • Open Access
5 Citations
4,980 Views
18 Pages

20 November 2019

Exposure of neonates to Mycobacterium avium subsp. paratuberculosis (MAP) via infected dams is the primary mode of transmission of Johne’s disease. Little is known about the impacts of feeding colostrum and supplemental vitamins on the gut micr...

  • Article
  • Open Access
2 Citations
4,840 Views
18 Pages

The Role of Phosphatidylinositol Mannosides in the Serological Diagnosis of Mycobacterial Infections

  • Ad P. Koets,
  • Marielle H. van den Esker,
  • Karel Riepema and
  • Douwe Bakker

13 November 2019

Accurate diagnosis of mycobacterial infections, such as bovine tuberculosis and paratuberculosis, remains challenging. Available direct diagnostic tests aimed at detecting the pathogen are highly specific but lack sensitivity, depending on the stage...

  • Article
  • Open Access
8 Citations
4,783 Views
12 Pages

Evaluation of in Vivo Response of Three Biphasic Scaffolds for Osteochondral Tissue Regeneration in a Sheep Model

  • Alberto M. Crovace,
  • Alessia Di Giancamillo,
  • Francesca Gervaso,
  • Laura Mangiavini,
  • Davide Zani,
  • Francesca Scalera,
  • Barbara Palazzo,
  • Daniela Izzo,
  • Marco Agnoletto and
  • Giuseppe M. Peretti
  • + 4 authors

9 November 2019

Osteochondral defects are a common problem in both human medicine and veterinary practice although with important limits concerning the cartilaginous tissue regeneration. Interest in the subchondral bone has grown, as it is now considered a key eleme...

  • Article
  • Open Access
4 Citations
4,662 Views
10 Pages

Purification and Characterisation of Badger IgA and Its Detection in the Context of Tuberculosis

  • Deanna Dalley,
  • Sandrine Lesellier,
  • Francisco J. Salguero and
  • Mark A. Chambers

2 November 2019

European badgers are a wildlife reservoir of bovine tuberculosis in parts of Great Britain. Accurate diagnosis of tuberculosis in badgers is important for the development of strategies for the control of the disease. Sensitive serological tests for b...

  • Article
  • Open Access
5 Citations
5,510 Views
18 Pages

Characterization of Ethanol Extracted Cell Wall Components of Mycobacterium avium Subsp. paratuberculosis

  • John P. Bannantine,
  • Ashutosh Wadhwa,
  • Judith R. Stabel and
  • Shigetoshi Eda

31 October 2019

Antigens extracted using ethanol (EtOH) and incorporated in the EtOH vortex ELISA (EVELISA) test have previously shown high specificity and sensitivity for detecting Mycobacterium avium subspecies paratuberculosis (Map) and M. bovis infections in cat...

  • Review
  • Open Access
16 Citations
6,721 Views
21 Pages

30 October 2019

In this review, information was summarized on endoparasites found in six non-domesticated neotropical animals. These mammals have the potential to be domesticated. The animals included three rodents, agouti (Dasyprocta leporina), lappe (Agouti paca),...

  • Article
  • Open Access
18 Citations
5,120 Views
11 Pages

Seroprevalences of Newly Discovered Porcine Pestiviruses in German Pig Farms

  • Anna Michelitsch,
  • Anja Dalmann,
  • Kerstin Wernike,
  • Ilona Reimann and
  • Martin Beer

25 October 2019

Several novel porcine pestiviruses that are linked to disease outbreaks in commercial pig farms were discovered during recent years. Bungowannah pestivirus (BuPV; new species Pestivirus F) causes sudden death in young pigs, but has only ever been iso...

  • Article
  • Open Access
3 Citations
5,595 Views
10 Pages

Mongoose (Herpestes auropunctatus) May Not Be Reservoir Hosts for Mycobacterium bovis in Fiji Despite High Population Density and Direct Contact with Cattle

  • Philip J. Hayton,
  • Richard J. Whittington,
  • Colin Wakelin,
  • Paul Colville,
  • Aoife Reid,
  • Leo Borja and
  • Jenny-Ann Toribio

24 October 2019

The presence of a wildlife reservoir for Mycobacterium bovis complicates the eradication of bovine tuberculosis (BTB) from domestic cattle populations. For the BTB eradication program in Fiji, there is concern about the small Indian mongoose (Herpest...

  • Review
  • Open Access
61 Citations
28,000 Views
14 Pages

Development of Dog Immune System: From in Uterus to Elderly

  • Maria Pereira,
  • Ana Valério-Bolas,
  • Cátia Saraiva-Marques,
  • Graça Alexandre-Pires,
  • Isabel Pereira da Fonseca and
  • Gabriela Santos-Gomes

21 October 2019

Immune system recognize and fight back foreign microorganisms and inner modifications that lead to deficient cell and tissue functions. During a dog’s life, the immune system needs to adapt to different physiological conditions, assuring survei...

  • Article
  • Open Access
3 Citations
4,650 Views
10 Pages

Genetically Related Mycobacterium bovis Strains Displayed Differential Intracellular Growth in Bovine Macrophages

  • Alejandro Benítez-Guzmán,
  • Hugo Esquivel-Solís,
  • Cecilia Romero-Torres,
  • Camila Arriaga-Díaz and
  • José A. Gutiérrez-Pabello

18 October 2019

Molecular typing of bacterial isolates provides a powerful approach for distinguishing Mycobacterium bovis (M. bovis) genotypes. It is known that M. bovis strain virulence plays a role in prevalence and spread of the disease, suggesting that strain v...

  • Article
  • Open Access
6 Citations
6,403 Views
9 Pages

Development and Evaluation of Epitope-Blocking ELISA for Detection of Antibodies against Contagious Caprine Pleuropneumonia in Goat Sera

  • Baziki Jean de Dieu,
  • Bodjo S. Charles,
  • Nick Nwankpa,
  • Ethel Chitsungo,
  • Cisse Rahamatou Moustapha Boukary,
  • Naomi Maina,
  • Takele A. Tefera,
  • Rume Veronica Nwankpa,
  • Nduta Mwangi and
  • Yao Mathurin Koffi

18 October 2019

Enzyme linked immunosorbent assays (ELISAs) have been developed for the detection of antibodies against contagious caprine pleuropneumonia (CCPP), the causative agent of which is Mycoplasma capricolum subsp. Capripneumoniae (Mccp). The currently avai...

  • Article
  • Open Access
7 Citations
5,960 Views
18 Pages

12 October 2019

Mycobacterium avium subspecies paratuberculosis (Map) causes chronic granulomatous disease in cattle and ruminant livestock, causing substantial economic losses. Current vaccines delay clinical signs but cannot train the immune system to fully eradic...

  • Article
  • Open Access
8 Citations
4,942 Views
12 Pages

9 October 2019

The ventricular filling velocities during diastole and the influence of isoflurane anesthesia on these blood flow velocities of the racing pigeon (n = 43) are evaluated by pulsed-wave (PW) Doppler sonography. Sonographic examination demonstrates an e...

  • Article
  • Open Access
9 Citations
4,740 Views
9 Pages

Reduced FXR Target Gene Expression in Copper-Laden Livers of COMMD1-Deficient Dogs

  • Xiaoyan Wu,
  • Hsiaotzu Chien,
  • Monique E. van Wolferen,
  • Hedwig S. Kruitwagen,
  • Loes A. Oosterhoff and
  • Louis C. Penning

30 September 2019

Wilson’s disease (WD), an autosomal recessive disorder, results in copper accumulation in the liver as a consequence of mutations in the gene ATPase copper transporting beta (ATP7B). The disease is characterized by chronic hepatitis, eventually resul...

  • Case Report
  • Open Access
5 Citations
6,894 Views
5 Pages

Sertoli Cell Tumor (SCT) in a Captive Black Bear (Ursus americanus)

  • Ahmed K. Elfadl,
  • SunYoung Park,
  • H M Arif Ullah,
  • Soong-Hee Youn,
  • Myung-Jin Chung,
  • Ji-Yoon Son,
  • Jae-Yeong Lee,
  • Seoung-Woo Lee,
  • A-Rang Lee and
  • Kyu-Shik Jeong
  • + 5 authors

26 September 2019

A black bear of 29-year-old (Ursus americanus) died unexpectedly in captivity without any gross lesions or clinical signs. We identified a firm, lobulated, yellowish tan, and well-circumscribed mass embedded inside the testicular tissue at the time o...

  • Communication
  • Open Access
3 Citations
12,092 Views
6 Pages

Successful Treatments and Management of A Case of Canine Melioidosis

  • Pacharapong Khrongsee,
  • Chulalak Lueangthuwapranit,
  • Thitsana Ingkasri,
  • Somporn Sretrirutchai,
  • Jedsada Kaewrakmuk,
  • Vannarat Saechan and
  • Apichai Tuanyok

23 September 2019

This communication presents a successful story of an attempt to treat and manage a case of canine melioidosis, a severe tropical disease caused by Burkholderia pseudomallei. A 10-year-old dog was trapped with barbed wires, causing an infected wound a...

  • Article
  • Open Access
6 Citations
8,230 Views
10 Pages

A Serosurvey of Multiple Pathogens in American Black Bears (Ursus americanus) in Pennsylvania, USA Indicates a Lack of Association with Sarcoptic Mange

  • Kevin D. Niedringhaus,
  • Justin D. Brown,
  • Mark A. Ternent,
  • Christopher A. Cleveland and
  • Michael J. Yabsley

20 September 2019

Infectious diseases, particularly of wildlife, are intrinsically linked to human and domestic animal health. Reports of sarcoptic mange in black bears (Ursus americanus) are increasing in multiple states in the USA and while the reason is unknown, ma...

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Vet. Sci. - ISSN 2306-7381