Oxidative Stress as a Therapeutic Target of Alzheimer’s Disease
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: 31 December 2024 | Viewed by 28
Special Issue Editors
Interests: medicinal chemistry; serotonin receptors; dopamine receptors; formyl peptide receptors; positron emission tomography; fluorescent ligands
Special Issues, Collections and Topics in MDPI journals
Interests: cell culture; transfection; cancer biology; pharmaceutical biotechnology; medicinal chemistry
Special Issue Information
Dear Colleagues,
Alzheimer’s Disease (AD) is a neurodegenerative disease characterized by a complex array of pathological factors, chiefly the deposition of amyloid β protein aggregates, which is accompanied by immune cell infiltration and neuroinflammation. This inflammatory process leads, in turn, to an overproduction of reactive oxygen and nitrogen species (ROS and RNS, respectively).
Researchers regularly debate the place of oxidative stress (OS) in the pathogenesis of AD, especially regarding its role as a cause or a consequence of neurodegenerative processes. While touted by some as promising therapeutic agents for AD, antioxidants are plagued by bioavailability issues that stifle their potential in this regard.
Thus, the picture is that of a highly dynamic topic of research on which much work remains to be carried out.
Hoping to provide our readers with an inspiring view on the topic, we invite you to submit your recent findings or a review article to our Special Issue centered on Alzheimer’s Disease.
Our goal is to gather the latest research on the role of OS in AD pathogenesis and the development of antioxidant compounds as potential AD therapeutics.
We welcome all approaches to studying AD pathophysiology.
We eagerly look forward to your contributions.
Dr. Marcello Leopoldo
Guest Editor
Dr. Leonardo Brunetti
Guest Editor Assistant
Manuscript Submission Information
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Keywords
- Alzheimer's disease
- neuroinflammation
- therapeutic agent
- oxidative stress
