Potential Health Benefits of Dietary Antioxidants

A special issue of Antioxidants (ISSN 2076-3921). This special issue belongs to the section "Health Outcomes of Antioxidants and Oxidative Stress".

Deadline for manuscript submissions: 30 August 2024 | Viewed by 2250

Special Issue Editor

Special Issue Information

Dear Colleagues,

Dietary antioxidants are a widespread family of molecules characterized by their chemical structure (e.g., phenols, vitamins, peptides, etc.), chemical–physical properties (e.g., lipophilic or hydrophilic), and activity (enzymatic or nonenzymatic). They mitigate oxidative stress due to excessive and uncontrolled reactive oxygen species (ROS; i.e., singlet oxygen, peroxynitrite, hydroxyl radical OH, superoxide ion O2, hydrogen peroxide H2O2) and free radical production. Exogenous (i.e., smoke, pollutants, and radiation) and endogenous factors (i.e., aerobic metabolism in mitochondria, enzymatic reactions, etc.) induce their production. Oxidative stress causes inflammation, cardiovascular diseases, neurodegenerative illnesses, asthma, senescence, cancer, and premature skin aging. Food's antioxidative capacity is determined by a range of compounds, some of which may not be identified after their metabolization. Depending on their concentration, specific antioxidants may lead to under- or overestimating antioxidant activity since they work synergistically. In recent years, the consumption of functional foods and food supplements containing food antioxidants has expanded exponentially. Recently, supplements based on single antioxidants and extracts containing food antioxidants have been formulated. Unfortunately, many antioxidants act as prooxidants at high concentrations, increasing to oxidative stress and inducing toxicity. This Special Issue aims to collect reviews and research articles in which dietary antioxidants' isolation, characterization, uses, delivery systems and toxicological aspects are reported. 

Dr. Irene Dini
Guest Editor

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Keywords

  • food antioxidants
  • food supplements
  • antioxidant activity
  • food antioxidant isolation
  • food antioxidant characterization
  • analytical method validation
  • antioxidant bioavailability
  • circular economy
  • sustainability

Published Papers (2 papers)

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Research

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16 pages, 530 KiB  
Article
Dietary Antioxidants May Support Cosmetic Treatment in Patients with Rosacea
by Kinga Zujko-Kowalska, Joanna Masłowska, Małgorzata Knaś-Dawidziuk, Jadwiga Hamulka and Małgorzata Elżbieta Zujko
Antioxidants 2024, 13(3), 381; https://doi.org/10.3390/antiox13030381 - 21 Mar 2024
Cited by 1 | Viewed by 1335
Abstract
Rosacea is a chronic skin disease that significantly reduces the quality of life (QoL) of patients. The aim of this study was to assess whether dietary antioxidants can support the effect of cosmetic treatment in improving the QoL of patients with rosacea. Basic [...] Read more.
Rosacea is a chronic skin disease that significantly reduces the quality of life (QoL) of patients. The aim of this study was to assess whether dietary antioxidants can support the effect of cosmetic treatment in improving the QoL of patients with rosacea. Basic data about participants (N = 160) were collected using a self-reported survey. QoL was assessed using the standardized Dermatology Life Quality Index (DLQI) questionnaire. An interventional cosmetic treatment was performed using cavitation peeling and sonophoresis with a commercial capillary repair serum. The study was registered as a clinical trial (NCT06271135). To assess antioxidant diet quality, for the first time, a new dietary antioxidant quality index (DAQI) was developed, which consisted of 12 items: dietary total antioxidant capacity, dietary polyphenols, phytosterols, lignans, vitamin C, vitamin E, β-carotene, zinc, iron, copper, manganese and selenium. It was found that the highest tertiles of DAQI diminished the odds about 40–45% of the moderate, large and extremely large effect of rosacea on QoL and about 8–11% of the occurrence of rosacea symptoms compared with the lowest tertile. This study showed that rosacea has a negative impact on QoL, but a comprehensive approach to treatment, including antioxidant cosmetic treatment and dietary antioxidants, can improve the QoL of patients with rosacea. Full article
(This article belongs to the Special Issue Potential Health Benefits of Dietary Antioxidants)
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Review

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26 pages, 975 KiB  
Review
A Systematic Review of Cardio-Metabolic Properties of Lonicera caerulea L.
by Larisa Bora, Adelina Lombrea, Stefan Laurentiu Batrina, Valentina Oana Buda, Oana-Maria Esanu, Oana Pasca, Cristina Adriana Dehelean, Stefania Dinu, Zorita Diaconeasa and Corina Danciu
Antioxidants 2024, 13(6), 694; https://doi.org/10.3390/antiox13060694 - 5 Jun 2024
Viewed by 521
Abstract
In the light of growing concerns faced by Western societies due to aging, natality decline, and epidemic of cardio-metabolic diseases, both preventable and treatable, new and effective strategical interventions are urgently needed in order to decrease their socio-economical encumbrance. The recent focus of [...] Read more.
In the light of growing concerns faced by Western societies due to aging, natality decline, and epidemic of cardio-metabolic diseases, both preventable and treatable, new and effective strategical interventions are urgently needed in order to decrease their socio-economical encumbrance. The recent focus of research has been redirected towards investigating the potential of haskap (Lonicera caerulea L.) as a novel functional food or superfruit. Therefore, our present review aims to highlight the latest scientific proofs regarding the potential of Lonicera caerulea L. (LC), a perennial fruit-bearing plant rich in polyphenols, in reversing cardio-metabolic dysfunctions. In this regard, a systematic search on two databases (PubMed and Google Scholar) from 1 January 2016 to 1 December 2023 was performed, the keyword combination being Lonicera caerulea L. AND the searched pharmacological action, with the inclusion criteria consisting of in extenso original articles, written in English. The health-enhancing characteristics of haskap berries have been examined through in vitro and in vivo studies from the 35 included original papers. Positive effects regarding cardiovascular diseases and metabolic syndrome have been assigned to the antioxidant activity, hypolipidemic and hypoglycemic effects, as well as to the hepatoprotective and vasoprotective potential. Latest advances regarding LCF mechanisms of action are detailed within this review as well. All these cutting-edge data suggest that this vegetal product would be a good candidate for further clinical studies. Full article
(This article belongs to the Special Issue Potential Health Benefits of Dietary Antioxidants)
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