Mitochondrial Shape Change in Physio-Pathology
A special issue of Antioxidants (ISSN 2076-3921).
Deadline for manuscript submissions: closed (30 November 2017) | Viewed by 111237
Special Issue Editor
Special Issue Information
Dear Colleagues,
Mitochondria produce cellular energy. Maintaining cellular energetics is an absolute requirement for cell and organ survival, and thus mitochondrial dysfunction is implicated in virtually every human disease. One of the prominent cell biological features of mitochondria is frequent change in shape and location, collectively termed mitochondrial dynamics. The subject of mitochondrial shape change, mainly mediated by fission and fusion, took the center stage of mitochondrial research 20 years ago. Despite its relatively short history, mitochondrial dynamics research has generated a great deal of insights into basic mechanisms, as well as pathophysiological roles, providing evidence that mitochondrial dynamics are an integral part of regulating cellular energetics.
The purpose of this Special Issue is to bring together the current states of mechanistic and physio–pathologic aspects in mitochondrial dynamics research. Mitochondrial dynamics has close connections to mitochondrial biogenesis, mitophagy, and cell death processes. In addition, it is involved in mitochondrial ROS production by regulating respiratory function, contributing to oxidative pathology in many disease conditions. This Special Issue invites original research and review articles on the subject of mitochondrial dynamics and all the related topics as indicated below.
Prof. Dr. Yisang Yoon
Guest Editor
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Keywords
- Mitochondrial dynamics
- Mitochondrial fission and fusion
- Mitochondrial dynamics in energetics
- Mitophagy
- Mitochondrial biogenesis
- Apoptosis
- ROS and oxidative stress
- Mitochondrial dynamics in human diseases
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