Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Probiotics and Gut Microbiome-Prospects and Challenges
edited by Jiye Cheng
submission deadline 31 Jan 2025 | Viewed by 179 | Submission Open
Keywords: probiotics; gut microbiome; microbiota; gut health; probiotic mechanisms; probiotic applications; probiotic challenges; probiotic formulation; probiotic delivery; microbiome-host interactions
(This special issue belongs to the Section Microbiology)
2nd Edition of Computational Methods in Biology
edited by and Chi Wei Ong
submission deadline 1 Feb 2025 | 2 articles | Viewed by 1950 | Submission Open
Keywords: computational biology; artificial intelligence; machine learning; bioinformatics; data analysis; genomics; proteomics; drug discovery systems biology; cancer research
(This special issue belongs to the Section Bioinformatics)
Feeding Biology and Nutrition in Insects
edited by and Christopher W. Weldon
submission deadline 15 Feb 2025 | Viewed by 482 | Submission Open
Keywords: diet; digestion; ecology; evolution; feeding; insects; mass-rearing; microbiome; nutrients; taste
(This special issue belongs to the Section Ecology)
Cardiovascular Autonomic Function: From Bench to Bedside
edited by and
submission deadline 28 Feb 2025 | 10 articles | Viewed by 28177 | Submission Open
Keywords: dysautonomia; heart rate variability; autonomic function testing; cardiovascular autonomic function; autonomic neuroscience; syncope; orthostatic hypotension; baroreflex
Structure, Function and Diversity of Gut Microbes in Animals
edited by
submission deadline 28 Feb 2025 | 6 articles | Viewed by 17570 | Submission Open
Keywords: microbes; gut; function; structure; diversity; benefit; pathogenesis; dysbiosis
(This special issue belongs to the Section Microbiology)
Innovative Biotechnologies for Advancing Protein Function Investigation
edited by Yongjuan Zhao, Wanhua Li and Qiwen Deng
submission deadline 28 Feb 2025 | 5 articles | Viewed by 8064 | Submission Open
Keywords: protein imaging and visualization; high-throughput screening; computational methodologies; protein engineering; protein– protein interactions; protein– ligand interactions; biological mechanisms
(This special issue belongs to the Section Biotechnology)
Physiological, Biochemical, and Molecular Response in Plants under Light-Emitting Diode (LED) Treatment (Volume II) submission deadline 28 Feb 2025 | 3 articles | Viewed by 6783 | Submission Open
Keywords: antioxidants; bioactive compounds; biotic and abiotic stress; food quality; LED; nutrients; plant defense; plant response; productivity
(This special issue belongs to the Section Plant Science)
Genetic Breeding and Reproduction of Aquatic Animals
edited by Dongmei Ma, , and Qingheng Wang
submission deadline 28 Feb 2025 | 3 articles | Viewed by 5890 | Submission Open
Keywords: genetic breeding; reproduction technology; gene; protein; molecular marker; trait; QTLs; molecular marker; fish; shrimp; crab; shellfish; aquatic animals; transcriptomics; proteomics; metabonomics
(This special issue belongs to the Section Reproductive Biology)
Physiology and Pathophysiology of Skin
edited by Seon-Pil Jin
submission deadline 28 Feb 2025 | 4 articles | Viewed by 3918 | Submission Open
Keywords: epidermal barrier; melanogenesis; wound healing; skin immunity; sensory perception; dermatitis; psoriasis; atopic dermatitis; autoimmune skin disorders; therapeutic approaches
(This special issue belongs to the Section Physiology)
Extracellular Vesicles and Pathophysiology
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 3113 | Submission Open
Keywords: extracellular vesicles; biomarkers; diagnostics; therapeutics; disease mechanism
Research Progress on Parasitic and Microbial Infection and Immunity submission deadline 28 Feb 2025 | 3 articles | Viewed by 2906 | Submission Open
Keywords: host; pathway; defense; innate immune responses; adaptive immune responses; pathogenicity; immune signalling; bacterial infection; viral infection; parasitic infection
(This special issue belongs to the Section Infection Biology)
Pathophysiology of Hypertension and Related Diseases submission deadline 28 Feb 2025 | 1 articles | Viewed by 2190 | Submission Open
Keywords: arterial hypertension; resistant hypertension; secondary hypertension; prevention and screening of hypertension; hypertensive crisis; treatment of hypertension; obstructive sleep apnoea syndrome; pathophsyiology of hypertension; hypertension and the environment; (pre)hypertension and genetics
(This special issue belongs to the Section Medical Biology)
Nutrition, Environment, and Fish Physiology
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 1844 | Submission Open
Keywords: fish; physiology; nutrition; environment; effects   TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Marine Biology)
Bioavailability, Metabolism, and Health Effects of Phenolic Compounds
edited by and Alice Cattivelli
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1727 | Submission Open
Keywords: phenolic compounds; gut microbiota; metabolism; cardiovascular diseases; cancer; anti-proliferative activity; bioavailability; bioaccessibility
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Pollination Biology
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1715 | Submission Open
Keywords: conservation biology; insect diversity; pollinator-plant interactions; ecosystem service; pollinator insect
(This special issue belongs to the Section Ecology)
Reproductive Management of Goats and Sheep
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 1619 | Submission Open
Keywords: reproductive management; goats; sheep; breeding; physiology; production; biology; theriogenology
(This special issue belongs to the Section Reproductive Biology)
Biological Control of Vegetable Diseases and Bacterial Molecular Biology
edited by Lei Li and Xiaofeng Zhou
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1362 | Submission Open
Keywords: bacterial diseases in horticulture; plant growth-promoting bacteria; biological control of pathogens via antagonistic bacteria; genomic; transcriptomic; proteomics studies of antagonistic or pathogenic bacteria interactions; beneficial effects of bacteria on plant resistance to biotic and abiotic stresses; pathogenic mechanism or biocontrol mechanism; volatile organic compounds; secondary metabolites
(This special issue belongs to the Section Microbiology)
Epibiosis in Aquatic Environments submission deadline 28 Feb 2025 | 1 articles | Viewed by 1304 | Submission Open
Keywords: conservation; biodiversity; animals; aquatic environments; marine biology; marine zoology; marine ecology; radiation biology; interspecific interactions; evolution
B and T Cells in HIV and Other Viral Infections
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1160 | Submission Open
Keywords: B cells; T cells; adaptive immunity; humoral immunity; cellular immunity; mucosal immunity; anti-viral immunity; broadly neutralizing antibodies; vaccine; immunological memory
(This special issue belongs to the Section Infection Biology)
Animal Models of Autoimmune Diseases
edited by Feng Zhu and Keqiang Chen
submission deadline 28 Feb 2025 | 1 articles | Viewed by 990 | Submission Open
Keywords: autoimmune disease; infection; innate immunity; inflammation; cancer risk; therapeutic target; adaptive immunity
(This special issue belongs to the Section Physiology)
Synaptic Function and Energy Use
edited by
submission deadline 28 Feb 2025 | Viewed by 511 | Submission Open
Keywords: presynapse; postsynapse; ATP; mitochondria; glia; pericyte; vasculature; fatty acids; ketone bodies; leptin; insulin; glucose; lactate
(This special issue belongs to the Section Neuroscience)
Genomic Insights into Algal Adaptation and Conservation
edited by and Jun Qian
submission deadline 28 Feb 2025 | Viewed by 284 | Submission Open
Keywords: algae genome; genetic engineering; genome editing; environment adaption; algal application
(This special issue belongs to the Section Marine Biology)
Recent Advances in Tumor Microenvironment Biology
edited by Hongbin Wang
submission deadline 28 Feb 2025 | Viewed by 260 | Submission Open
Keywords: tumor microenvironment; immune cells’ stromal cells; extracellular matrix; angiogenesis; metabolic reprogramming; tumor-associated macrophages; tumor-infiltrating lymphocytes; cytokine signaling; therapeutic targeting strategies  
(This special issue belongs to the Section Cancer Biology)
Stem Cells in Neurological Disorders: Challenges and Opportunities
edited by Ying Liu and Qi Lin Cao
submission deadline 28 Feb 2025 | Viewed by 251 | Submission Open
Keywords: stem cell research; neurological disorders; induced pluripotent stem cells (iPSCs); cell replacement therapy; gene editing in neurology; stem cell-derived exosomes; neuroregeneration; disease modeling; neuroprotective strategies; regenerative medicine
(This special issue belongs to the Section Neuroscience)
Machine Learning in Biomedical Engineering
edited by Tao Huang
submission deadline 28 Feb 2025 | Viewed by 222 | Submission Open
Keywords: machine learning; biomedical engineering; digital twin; big data; cancer; drug
(This special issue belongs to the Section Bioinformatics)
Multi-omics Approaches in Agricultural Crops to Unravel Responses to Environmental Stresses and Advance Sustainable Agriculture
edited by
submission deadline 28 Feb 2025 | Viewed by 208 | Submission Open
Keywords: plant functional genomics; environmental stress; climate change; crop yield; crop quality; nutritional properties; omics approaches; genomics; transcriptomics; proteomics; metabolomics; epigenomics; phenomics; stress-tolerant crops; breeding strategies; data integration; systems biology; sustainable agriculture; underutilized crops; orphan crops; beneficial microorganisms
(This special issue belongs to the Section Plant Science)
Cancer and Signalling: Targeting Cellular Pathways
edited by
submission deadline 31 Mar 2025 | 9 articles | Viewed by 16172 | Submission Open
Keywords: Hippo signalling; mechanotransduction; YAP; cancer; polarity; Rho GTPases; signalling; organ growth; extracellular matrix; integrins
(This special issue belongs to the Section Cancer Biology)
Male Disorders: Fertility Care and Support, Preservation and Restoration
edited by
submission deadline 31 Mar 2025 | 6 articles | Viewed by 11904 | Submission Open
Keywords: cancer; fertility; cryopreservation; spermatozoa; testicular; in vitro spermatogenesis; cell transplantation; graft; male
(This special issue belongs to the Section Reproductive Biology)
Current Advances in Echinoderm Research
edited by and
submission deadline 31 Mar 2025 | 7 articles | Viewed by 11592 | Submission Open
Keywords: echinoderms; sea cucumbers; starfish; brittle stars; sea urchins
Recent Advances in Soil Health: Influences of Organic Carbon and Microbiota
edited by , Audrius Gegeckas and
submission deadline 31 Mar 2025 | 3 articles | Viewed by 10659 | Submission Open
Keywords: diversity of soil microbial community; soil microbial function in environment; soil microbiomics; carbon sequestration; soil organic matter (SOM); soil organic carbon (SOC); soil quality; plant– soil microbial interaction; eco-friendly agriculture; biofertilizers
(This special issue belongs to the Section Microbiology)
Physiological and Pathophysiological Responses to Biomaterials 2.0: From Nano- to Microscale Effects and Interactions submission deadline 31 Mar 2025 | 3 articles | Viewed by 7233 | Submission Open
Keywords: extracellular stimuli and physiological responses; plasma membrane interface; cell– material interactions; tissue– material interactions; tissue engineering; biomaterials; biomedical devices; in vitro models and on-chip/microfluidic systems; bioreactors; structure– function relationship
(This special issue belongs to the Section Physiology)
Editorial Board Members’ Collection Series: The Dynamics of RNA–Protein Interactions
edited by and
submission deadline 31 Mar 2025 | 3 articles | Viewed by 5841 | Submission Open
Keywords: RNA-binding proteins; mRNA splicing; mRNA decay; mRNA translation; RNA localization; microRNAs; siRNAs; long noncoding RNAs; phase separation; RNA granules; membraneless organelles
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Advances in Biological Breast Cancer Research
edited by Anna Mart Engelbrecht, and
submission deadline 31 Mar 2025 | 4 articles | Viewed by 5602 | Submission Open
Keywords: breast cancer; breast tumor; breast cancer cells; animal models; cell death; cancer diagnosis; cancer treatment; biomarkers; cancer microenvironment; carcinogens; estrogen receptor; molecular biology; cell biology
(This special issue belongs to the Section Cancer Biology)
Biology of Liver Diseases submission deadline 31 Mar 2025 | 3 articles | Viewed by 4581 | Submission Open
Keywords: viral hepatitis; alcoholic hepatitis; non-alcoholic steatohepatitis; autoimmune hepatitis; primary biliary cholangitis; liver cirrhosis; liver cancer; portal hypertension
(This special issue belongs to the Section Medical Biology)
Genetic Resources and Gene Editing Tools for Plant Resistance: Recent Advancements and Future Perspectives
edited by
submission deadline 31 Mar 2025 | 2 articles | Viewed by 3946 | Submission Open
Keywords: abiotic stress; biotic stress; crop improvement; genome editing; plant resistance
(This special issue belongs to the Section Plant Science)
Ecophysiology and Environmental Health: Assessing the Impact of Pollutants on Biodiversity and Ecosystem Function
edited by , Maíra Ignacio Sarmento and
submission deadline 31 Mar 2025 | 2 articles | Viewed by 3197 | Submission Open
Keywords: ecophysiology; ecotoxicology; environmental health; pollutants; global change; one health; ecosystem functioning; plant ecophysiology; agricultural and forest crops
Discovering the Physiological Significance and Regulatory Mechanisms of Circadian Rhythm Generation
edited by Xiaodong Li
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1857 | Submission Open
Keywords: circadian rhythms; biological clocks; chromatin; transcription; histone; nucleosome; pausing; pause release
(This special issue belongs to the Section Genetics and Genomics)
Pathophysiology of Testis
edited by María Susana Theas, and María Noel Galardo
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1592 | Submission Open
Keywords: testis; infertility; aging; inflammation; spermatogenesis; steroidogenesis; energy balance
(This special issue belongs to the Section Physiology)
Diet-Microbiota Impacts on Health
edited by Guilherme Zweig Rocha
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1553 | Submission Open
Keywords: intestinal microbiota; diet; inflammation
(This special issue belongs to the Section Immunology)
The Emerging Role of Mitochondria in Neurobiology submission deadline 31 Mar 2025 | 1 articles | Viewed by 1503 | Submission Open
Keywords: mitochondrial dynamics; neurodegenerative diseases; neuronal bioenergetics; synaptic function; neurogenesis; neuronal plasticity
(This special issue belongs to the Section Neuroscience)
Circular RNA Biology and Roles in Diseases
edited by Nan Wu and
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1421 | Submission Open
Keywords: RNA biology; diseases; circRNAs
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Proteomics and Human Diseases
edited by Lei Fang
submission deadline 31 Mar 2025 | 2 articles | Viewed by 1352 | Submission Open
Keywords: proteomics; clinical proteomics; human diseases; biomarker identification; therapeutic target; molecular mechanism; cancers; metabolic diseases; cardiovascular diseases; neurodegeneration diseases
(This special issue belongs to the Section Medical Biology)
Physiology of Lymph Vessels: Structure, Function and Modelling (Volume II)
edited by
submission deadline 31 Mar 2025 | Viewed by 413 | Submission Open
Keywords: lymphatic vessel; oedema; lymphatic muscle; spontaneous contractions; functional imaging; translational medicine; intrinsic pumping; extrinsic pumping; fluid homeostasis; numerical modelling
(This special issue belongs to the Section Physiology)
Unveiling Disease Molecular Signaling Pathways: Targeted Drug Discoveries for Pathway Modulation
edited by Stephen P. Wren
submission deadline 31 Mar 2025 | Viewed by 408 | Submission Open
Keywords: signaling molecules; disease mechanisms and pathways; small-molecule therapeutics
(This special issue belongs to the Section Medical Biology)
Genetic Mechanisms in Archaea submission deadline 31 Mar 2025 | Viewed by 384 | Submission Open
Keywords: archaea; extrachromosomal genetic elements; chromosome structure; DNA replication; DNA repair; DNA recombination; transcription regulation; epigenetic regulation         TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in French   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate French to Simplified Chinese Never translate French Never translate admin.mdpi.com
(This special issue belongs to the Section Microbiology)
Animal Models of Gastrointestinal Diseases
edited by Yan Hu
submission deadline 31 Mar 2025 | Viewed by 300 | Submission Open
Keywords: gastrointestinal diseases; animal models; digestive system; inflammatory bowel diseases; colorectal cancer; disease pathology; research methodologies; therapeutic interventions; clinical applications; translational research
(This special issue belongs to the Section Physiology)
Gene–Environment Interactions in Evolutionary Developmental Biology
edited by Alexander Shingleton
submission deadline 31 Mar 2025 | Viewed by 274 | Submission Open
Keywords: phenotypic plasticity; gene– environment interactions; genetic architecture of plasticity; mechanisms of phenotypic variation; anthropogenic stressors; evolution of plastic responses
(This special issue belongs to the Section Evolutionary Biology)
Innate Immunity and Inflammatory Diseases
edited by Veera Ganesh Yerra, Santosh Reddy Sukka and Anil Kumar Kalvala
submission deadline 31 Mar 2025 | Viewed by 223 | Submission Open
Keywords: innate immunity; inflammation; immunotherapy; immune cells; inflammatory diseases
(This special issue belongs to the Section Immunology)
Extracellular Vesicles: Biogenesis and Functions in the Complex Landscape of Differentiation and Disease
edited by
submission deadline 31 Mar 2025 | Viewed by 211 | Submission Open
Keywords: stem cell biology; stem cell differentiation; adipogenesis; neurogenesis; extracellular vesicles in stem cell differentiation; ncRNAs; tumor microenvironment; intercellular communication
(This special issue belongs to the Section Cell Biology)
Artificial Intelligence Research for Complex Biological Systems
edited by and Milana Frenkel-Morgenstern
submission deadline 31 Mar 2025 | Viewed by 144 | Submission Open
Keywords: deep learning; generative artificial intelligence; bioinformatics; complex biological systems; cancer; neuroscience; next-generation sequencing; single-cell and bulk omics; genomics
(This special issue belongs to the Section Bioinformatics)
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