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Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Neurobiology of Traumatic Brain Injury

edited by

Ioannis Mavroudis

and Dimitrios A. Kazis

submission deadline 31 Mar 2025 | Viewed by 119 | Submission Open

Keywords: traumatic brain injury (TBI); neuroinflammation; neuroplasticity; neurodegeneration; molecular pathways; genetic factors; diagnostic tools; therapeutic strategies; rehabilitation techniques; chronic neurological conditions

(This special issue belongs to the Section Neuroscience)

Mitochondria: The Signaling Organelle

edited by

Nathan Lanning

submission deadline 15 Apr 2025 | 2 articles | Viewed by 2655 | Submission Open

Keywords: mitochondria; signal transduction; homeostasis; metabolism; apoptosis; redox biology; organelle communication

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Bird Biology and Conservation

edited by

Alessandro Ferrarini

submission deadline 15 Apr 2025 | 2 articles | Viewed by 1875 | Submission Open

Keywords: avian conservation; ecological modeling; GIS; spatial ecology; telemetry

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Multi-omics Data Integration in Complex Diseases

edited by

Min Zhao

Ruifeng Hu

and

Dario Di Silvestre

submission deadline 30 Apr 2025 | 13 articles | Viewed by 30704 | Submission Open

Keywords: omics; disease; data integration; bioinformatics; genome

(This special issue belongs to the Section Bioinformatics)

Applications of Stable Isotope Analysis in Ecology

edited by

Edoardo Calizza

Giulio Careddu

and

Maria Letizia Costantini

submission deadline 30 Apr 2025 | 7 articles | Viewed by 22700 | Submission Open

Keywords: community ecology; population ecology; biotic interactions; food webs; nutrient cycling; ecosystem structure and functioning; disturbance; stability; environmental change; climate change; invasive species

(This special issue belongs to the Section Ecology)

Coping with Temperature Increase Induced by Climate Warming: Trends in Ectothermic Species

edited by

Andreas Walzer

submission deadline 30 Apr 2025 | 8 articles | Viewed by 19430 | Submission Open

Keywords: biodiversity; climate warming; ectothermic species; geographic ranges; heat waves; evolutionary adaptations; phenotypic plasticity; species interactions; thermal acclimation

Biology, Ecology and Management of Invasive Alien Plants

edited by

Guoqi Chen

and

Jiang Wang

submission deadline 30 Apr 2025 | 8 articles | Viewed by 11579 | Submission Open

Keywords: changes in the composition and distribution of alien plants; invasive mechanism; invasiveness; invasibility; invasive population; invasive plant interactions with other organisms; impacts on environment; ecosystem services and human health; chemical control; management of invasive plants; utilization of invasive plants

(This special issue belongs to the Section Plant Science)

Pathogenic Factors and Key Pathways of Metabolic Diseases

edited by Aijun Qiao

submission deadline 30 Apr 2025 | 3 articles | Viewed by 9938 | Submission Open

Keywords: metabolism diseases; lipid overload; insulin resistance; pathogenic molecules; biomarkers; drug therapy

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Physiology and Pathophysiology of Obesity

edited by Yifei Kang

submission deadline 30 Apr 2025 | 5 articles | Viewed by 5438 | Submission Open

Keywords: dietary intervention; alternative food; food supplementation; weight loss; weight management; obesity comorbidities; obesity pathophysiology

(This special issue belongs to the Section Physiology)

Biology, Ecology, Management and Conservation of Canidae

edited by Alberto Meriggi and

Francesco Maria Angelici

submission deadline 30 Apr 2025 | 3 articles | Viewed by 4914 | Submission Open

Keywords: Canidae; biology; ecology; management; conservation; ecosystem; habitats; niches; biodiversity; physiology; reproduction

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Effects of Heavy Metals and Microplastics on Wetland Biodiversity and Ecosystem Function

edited by Hualong Hong and Mohammad Belal Hossain

submission deadline 30 Apr 2025 | 1 articles | Viewed by 4421 | Submission Open

Keywords: heavy metals; microplastics; wetland ecosystems; ecology; risk assessment; food chain; health risk; emerging contaminants; water and sediment contamination; ecosystem health; exposure; polythelene

(This special issue belongs to the Section Ecology)

Gut Immunity, Inflammation, and Allergy

edited by

Mi-hee Park

submission deadline 30 Apr 2025 | 2 articles | Viewed by 3067 | Submission Open

Keywords: gut immunity; inflammation; allergy; nutrients; therapeutic agents; molecular biology

(This special issue belongs to the Section Immunology)

Neurogenetics of Behaviour

edited by

Charalambos Kyriacou

and

Ezio Rosato

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2924 | Submission Open

Keywords: behaviour; genetics; molecules; species; brain; networks; health; disease

(This special issue belongs to the Section Genetics and Genomics)

Application of Metabolomics and Integrated Computing in Chemical Biology

edited by

Saheed Sabiu

submission deadline 30 Apr 2025 | 1 articles | Viewed by 2449 | Submission Open

Keywords: chemical biology; computational biology; metabolomics; computational modeling; new chemical entities (NCE); active pharmaceutical ingredients (API); characterization; metabolite profiling

The Expression and/or Role of Glycoconjugates in Physiological and Pathological Conditions

edited by

Leonardo Freire-de-Lima

Leonardo Marques Da Fonseca

Célio Geraldo Freire-de-Lima

and

Alexandre Morrot

submission deadline 30 Apr 2025 | Viewed by 789 | Submission Open

Keywords: glycobiology; glycoproteins; glycolipids; glycosyltransferases; glycoconjugates

Understanding the Molecular Basis of Genetic Dental Diseases

edited by Yuta Chiba

submission deadline 30 Apr 2025 | Viewed by 310 | Submission Open

Keywords: genetic diseases; dental anomaly; genetic abnormality related to dental diseases; tooth development; molecular biology of tooth development

(This special issue belongs to the Section Biochemistry and Molecular Biology)

AI Deep Learning Approach to Study Biological Questions (2nd Edition)

edited by

Chung-Der Hsiao

and

Tzong-Rong Ger

submission deadline 30 Apr 2025 | Viewed by 268 | Submission Open

Keywords: OpenCV; Mask RCNN; YOLO; U-Net; StarDist; ImageJ; MATLAB; image segmentation; image classification; locomotion trajectory analysis; volumetric prediction; plants; animals; protozoa; invertebrates; animal behavior; developmental biology; toxicology; zebrafish; medaka; daphnia

Computational Modeling of Drug Delivery

edited by

Dingding Han

and Arezoo M. Ardekani

submission deadline 30 Apr 2025 | Viewed by 221 | Submission Open

Keywords: computational modeling; drug delivery; computational fluid dynamics; biofluids; quantitative biotransport; mathematical models; artificial intelligence

(This special issue belongs to the Section Biophysics)

Zoonotic Diseases

edited by

Francesca Mancianti

and

Valentina Virginia Ebani

submission deadline 30 Apr 2025 | Viewed by 173 | Submission Open

Keywords: zoonoses; zoonotic agents; bacteria; viruses; fungi; protozoa; helminths

(This special issue belongs to the Section Infection Biology)

Machine Learning Applications in Biology—2nd Edition

edited by

Georgios K. Georgakilas

submission deadline 30 Apr 2025 | Viewed by 112 | Submission Open

Keywords: machine learning; genomics; epigenomics; genetic variation and the environment; gene regulatory networks; integration of multipurpose NGS data

(This special issue belongs to the Section Bioinformatics)

Mechanisms of Drug Resistance in Cancer Cells

edited by

Xin Chen

Tuoen Liu

and

Wei Lei

submission deadline 30 Apr 2025 | Viewed by 100 | Submission Open

Keywords: drug resistance; mechanisms; cell growth; cell proliferation; efficacy

(This special issue belongs to the Section Medical Biology)

Plant-Microbe Interaction: The Cellular Mechanism Influence Plant Health

edited by

Wei Zhang

and Gongjun Shi

submission deadline 30 Apr 2025 | Viewed by 76 | Submission Open

Keywords: plant-microbe interaction; plant health; plant immunity; gene-for-gene model; resistosomes; metabolic crosstalk; climate change

The Impact of Climate Change on Quality, Yield, and Nutritional Properties of Cereals, Legumes, and Oilseeds

edited by

Vito Butardo

submission deadline 1 May 2025 | Viewed by 197 | Submission Open

Keywords: climate change; cereals; legumes; oilseeds; grain quality; seed nutrition; yield; elevated temperatures; drought; salinity; atmospheric CO2; multi-omics; field trials; crop modelling; data integration; climate resilience; breed-ing strategies; agronomic practices; beneficial microorganisms; underutilised crops; orphan crops

(This special issue belongs to the Section Plant Science)

Plant Epigenetics: Advancing Adaptation Strategies for Climate Change

edited by Qingzhu Zhang,

Shahid Ali

and Bowei Chen

submission deadline 1 May 2025 | Viewed by 44 | Submission Open

Keywords: mechanistic insights into epigenetic regulation; epigenetic memory and transgenerational inheritance; advances in epigenetic tools and techniques; epigenomics and phenotypic plasticity; implications for agriculture and conservation; tree epigenetic responses to climate change

(This special issue belongs to the Section Plant Science)

Internal Defense System and Evolution of Aquatic Animals

edited by

Alessio Alesci

submission deadline 15 May 2025 | 5 articles | Viewed by 6368 | Submission Open

Keywords: internal defense system; evolution; aquatic animals; immunology; aquatic environment; biodiversity; pollution; ecosystems

(This special issue belongs to the Section Evolutionary Biology)

Microbial Contamination and Food Safety (Volume II)

edited by

Joana Barbosa

submission deadline 15 May 2025 | 2 articles | Viewed by 6362 | Submission Open

Keywords: food contamination; food safety practices; microbial inactivation; microbial safety; microbiological hazards

(This special issue belongs to the Section Microbiology)

Role of the Human Gut Microbiota in Health and Disease

edited by Jerome Gay-Quéheillard

submission deadline 21 May 2025 | Viewed by 157 | Submission Open

Keywords: microbiota; dysbiosis; gut epithelial barrier; IBD; brain– gut axis; obesity; anxiety; depression; immune system; prebiotics; probiotics

The Biology of Animal Reproduction

edited by

Jingli Tao

submission deadline 30 May 2025 | Viewed by 8 | Submission Open

Keywords: the regulation of animal reproduction; follicular development and atresia; gamete and embryo development; hormonal control of reproductive processes; epigenetic regulation in reproductive biology

(This special issue belongs to the Section Reproductive Biology)

Biology, Ecology and Management of Aquatic Macrophytes

edited by

Jinlin Liu

, Shuang Zhao and

Wei Liu

submission deadline 31 May 2025 | 9 articles | Viewed by 11361 | Submission Open

Keywords: aquatic macrophytes; ecological planning and management; harmful algal blooms and control; biological resources and environment; mangrove forest; ecological restoration; biodiversity; plant physiology; water security

(This special issue belongs to the Section Plant Science)

Application of Bioinformatics to Unravel the Molecular Mechanisms of Cancer Biology

edited by

Yuanyan Xiong

submission deadline 31 May 2025 | 3 articles | Viewed by 3231 | Submission Open

Keywords: cancer biology; bioinformatics; genetics; epigenetics; transcriptomics

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Animal Models for Disease Mechanisms

edited by

Isabel R. Dias

submission deadline 31 May 2025 | 3 articles | Viewed by 3220 | Submission Open

Keywords: animal models; spontaneous models; induced models; disease mechanisms; pathogenesis research

(This special issue belongs to the Section Zoology)

Repair and Regeneration of Skeletal Muscle

edited by Huili Tong

submission deadline 31 May 2025 | 1 articles | Viewed by 1973 | Submission Open

Keywords: skeletal muscle; sarcopenia; atrophy; muscle satellite cells; regeneration and repair

(This special issue belongs to the Section Developmental Biology)

Immune Microenvironment and Molecular Mechanism of Glioma

edited by Carolina Cristina Jancic

submission deadline 31 May 2025 | 2 articles | Viewed by 1870 | Submission Open

Keywords: gliomas; tumor microenvironment; immune response; tumor evasion; tumor resistance; immunotherapy TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian // TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back // This page is in Latin Translate to Simplified Chinese Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh Always translate Latin to Simplified ChinesePRO Never translate Latin Never translate admin.mdpi.com

(This special issue belongs to the Section Cancer Biology)

Stem Cells in Experimental Medicine

edited by Xinhua Liao and

Xusheng Wang

submission deadline 31 May 2025 | 1 articles | Viewed by 1062 | Submission Open

Keywords: adult stem cells; induced pluripotent stem cells (iPSs); embryonic stem cells; progenitor cells; stem-cell-derived organoids; stem-cell-derived exosomes; stem-cell-based therapy; stem-cell-based disease modeling; stem-cell-based tissue engineering

(This special issue belongs to the Section Cell Biology)

Genetic Variability within and between Populations

edited by

Sankar Subramanian

submission deadline 31 May 2025 | 1 articles | Viewed by 910 | Submission Open

Keywords: genetic structure; population differentiation; FST or fixation index; migration; gene flow; admixture; heterozygosity; inbreeding; coalescence time; allele frequency; random mating

(This special issue belongs to the Section Evolutionary Biology)

Aquatic Animal Nutrition and Feed

edited by Yun Wang

submission deadline 31 May 2025 | 1 articles | Viewed by 885 | Submission Open

Keywords: aquaculture; aquatic animals; nutrition; aquatic feed; immunity; metabolism

Mechanisms Underlying Neuronal Network Activity

edited by Jorge Flores-Hernandez

submission deadline 31 May 2025 | Viewed by 672 | Submission Open

Keywords: neurons; brain circuits; NMDA receptors; acetylcholine; excitability; Parkinson’ s; schizophrenia; learning; attention

(This special issue belongs to the Section Neuroscience)

From Conception to Birth: Embryonic Development and Disease

edited by

Paschalis Theotokis

, Soultana Meditskou and

Maria Eleni Manthou

submission deadline 31 May 2025 | 1 articles | Viewed by 424 | Submission Open

Keywords: embryology; organogenesis; cell differentiation; gametes; reproduction; sex ratio; birth defects; pathophysiology; disease

(This special issue belongs to the Section Reproductive Biology)

Understanding and Targeting Biological Mechanisms of Heart Failure (2nd Edition)

edited by

Lei Ye

and

Wuqiang Zhu

submission deadline 31 May 2025 | Viewed by 372 | Submission Open

Keywords: developmental biology; genetics; stem cells; heart failure; cell therapy

(This special issue belongs to the Section Biochemistry and Molecular Biology)

Young Researchers in Conservation Biology and Biodiversity

edited by

Ettore Randi

submission deadline 31 May 2025 | Viewed by 210 | Submission Open

Keywords: population genomics and diversity; heterozygosity; inbreeding; hybridization; adaptive introgression; natural selection; speciation; bottleneck and population fragmentation; genetic drift; gene flow; extinction risk; evolvability; paleogenomics; phylogeography; conservation units; ecotypes; phylogenetics and systematics; eDNA; non-invasive genetic sampling; environmental monitoring

(This special issue belongs to the Section Conservation Biology and Biodiversity)

Exposure to Heavy Metals: Advances in Cytotoxicity and Genotoxicity

edited by Qianru Chi

submission deadline 31 May 2025 | Viewed by 207 | Submission Open

Keywords: heavy metal pollutants; exposure assessment; toxic mechanism; biomarkers; metabolomics; environmental quality monitoring; bioinformatics analysis methods

(This special issue belongs to the Section Toxicology)

Unraveling the Influence of Genetic Variants on Gene Regulation

edited by Marcio A.A. Almeida

submission deadline 31 May 2025 | Viewed by 181 | Submission Open

Keywords: genetics; genomics; gene expression analysis; EQTL identification; machine learning and artificial intelligence

(This special issue belongs to the Section Genetics and Genomics)

The Biology and Behavior of Bees

edited by

Dimitrios Kanelis

submission deadline 31 May 2025 | Viewed by 174 | Submission Open

Keywords: pollinators; bee anatomy; bee foraging behavior; bee communication; bee social structure; environmental stressors of bees; effect of pesticide on bees’ behavior; bees’ habitat loss; natural enemies of bees; bees’ disease management

(This special issue belongs to the Section Zoology)

Research Progress on Salt Stress in Plants

edited by

Yan Cheng

submission deadline 31 May 2025 | Viewed by 168 | Submission Open

Keywords: salt stress; plants; crops; soil salinization; salt tolerance; abiotic stress; plant protection; plant breeding

(This special issue belongs to the Section Plant Science)

Cotton: Genomics, Biotechnology and Molecular Breeding

edited by

Zhongxu Lin

submission deadline 31 May 2025 | Viewed by 163 | Submission Open

Keywords: cotton; genomics; functional genomics; biotechnology; germplasm; QTL mapping; molecular breeding

(This special issue belongs to the Section Plant Science)

Understanding Syncope: Multidisciplinary Approaches to Diagnosis and Management

edited by

Isabel Rocha

and Laranjo Sergio

submission deadline 31 May 2025 | Viewed by 114 | Submission Open

Keywords: syncope; diagnostic strategies; prognostication; treatment options; quality of life; wearable devices; artificial intelligence; autonomic dysfunction; orthostatic hypotension; POTS (postural orthostatic tachycardia syndrome)

(This special issue belongs to the Section Neuroscience)

Animal Models of Retinal Degenerative Diseases

edited by Elliot H. Choi and Marco Bassetto

submission deadline 31 May 2025 | Viewed by 111 | Submission Open

Keywords: retinal degeneration; inherited retinal diseases; retina; retinal pigment epithelium; animal models; photoreceptors; retinal ganglion cells; choroid; neovascularization

(This special issue belongs to the Section Neuroscience)

From the Eye to the Brain: Current Progress in Elucidating the Neural Circuit Dynamics Underlying Visual Processing

edited by Manuel Gomez-Ramirez

submission deadline 31 May 2025 | Viewed by 94 | Submission Open

Keywords: calcium imaging; optogenetics; ultrasound; 2-photon imaging; non-human primates; humans; optics; neurons; dendrites

(This special issue belongs to the Section Neuroscience)

Wetland Ecosystems (2nd Edition)

edited by

Jian Li

, Chenglang Pan and Qiang Wang

submission deadline 1 Jun 2025 | 7 articles | Viewed by 5538 | Submission Open

Keywords: biological invasion; pollution; carbon sink function; the biogeochemical cycle of biogenic elements; population and community ecology; global climate change; coastal zone management; the structure and function of the microbiome; environmental adaptation mechanisms of wetland organisms; wetland landscape; wetland degradation

(This special issue belongs to the Section Ecology)

Biomarkers in Stress Biology and Ecology

edited by