Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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The Molecular and Cellular Mechanisms of Lung Injury and Recovery
edited by Weiguo Chen, Honglong Ji and Ibra S. Fancher
submission deadline 30 Sep 2026 | 2 articles | Viewed by 1639 | Submission Open
Keywords: acute lung injury; chronic lung injury; ARDS; fibrosis; allergy; mechanisms; therapy; infection; inflammation; endothelial barrier
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Physiology and Ecology of Animal Parasites and Related Diseases
edited by Marcela K. Castelo
submission deadline 30 Sep 2026 | 1 articles | Viewed by 1135 | Submission Open
Keywords: parasites; parasitoids; physiology; ecology; ecophysiology; diseases; global change
(This special issue belongs to the Section Zoology)
Adaptation of Living Species to Environmental Stress (2nd Edition)
edited by and Sonia Del Prete
submission deadline 30 Sep 2026 | 2 articles | Viewed by 898 | Submission Open
Keywords: adaptation; environmental stress; evolutionary response; physiological adaptation; behavioral adaptation; morphological adaptation; climate change; conservation biology; biodiversity; ecological resilience; sound waves
(This special issue belongs to the Section Ecology)
Molecular Mechanisms of Cell Signal Transduction
edited by
submission deadline 30 Sep 2026 | Viewed by 741 | Submission Open
Keywords: molecular interactions in signaling; phosphorylation and signal propagation; post-translational modifications; cross-talk between signaling pathways; cellular response to extracellular stimuli; metabolic regulation and signaling; signaling in cancer progression; inflammatory signaling pathways; role of signaling in stem cell differentiation; innovative imaging techniques for signaling
(This special issue belongs to the Section Cell Biology)
Environmental and Hormonal Modulators of Cell Fate: Epigenetic and Phenotypic Plasticity in Somatic Tissues
edited by Alireza R. Fazeli and
submission deadline 30 Sep 2026 | 1 articles | Viewed by 681 | Submission Open
Keywords: cell fate; epigenetic regulation; phenotypic plasticity; hormonal signaling; environmental stressors; endocrine disruptors; somatic tissues; senescence; reprogramming; non-coding
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Genetics and Epigenetics of Neurological Disorders
edited by
submission deadline 30 Sep 2026 | 1 articles | Viewed by 551 | Submission Open
Keywords: neurological disorders; neurogenetics; genomics; epigenomics; DNA methylation; precision medicine
(This special issue belongs to the Section Neuroscience)
More than a Shield: The Secret Functions of Epithelial Cells in Homeostasis and Infections
edited by and Na Zhao
submission deadline 30 Sep 2026 | Viewed by 519 | Submission Open
Keywords: epithelial diversity; signaling; homeostasis; immunity; infection; microbiome; inflammation; cytokines; antimicrobial peptides
(This special issue belongs to the Section Medical Biology)
Bone Physiology and Development
edited by , and Yohei Abe
submission deadline 30 Sep 2026 | Viewed by 318 | Submission Open
Keywords: osteology; osteogenesis; bone growth; bone physiology; bone morphology; bone pathology; bone imaging
(This special issue belongs to the Section Physiology)
Molecular Mechanisms of Retina Development and Degeneration
edited by
submission deadline 30 Sep 2026 | Viewed by 302 | Submission Open
Keywords: retina; retinal development; retinal degeneration; molecular mechanisms; signaling pathways; genetic regulation; epigenetics; neuronal and glial interactions; neuroinflammation
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Cytogenetics and Cytogenomics in Insects submission deadline 30 Sep 2026 | Viewed by 267 | Submission Open
Keywords: insects; chromosomes; cytogenomics; next generation; cytogenetics
(This special issue belongs to the Section Genetics and Genomics)
Antibiotic Resistance Mechanisms: Ecological Implications
edited by
submission deadline 30 Sep 2026 | Viewed by 251 | Submission Open
Keywords: antibiotic resistance in environmental bacteria; antibiotics in the environment; ecological consequences of antibiotic resistance; antibiotic synergies and antagonisms with environmental pollutants; biomarkers of antibiotic resistance in the environment
(This special issue belongs to the Section Microbiology)
Ecological Interactions and Adaptive Strategies in Wildlife
edited by
submission deadline 30 Sep 2026 | Viewed by 217 | Submission Open
Keywords: biological pest control; predator– prey dynamics; avian reproductive ecology; evolutionary traits; human– wildlife coexistence; invasive species impacts; artificial nest ecology; ecosystem
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Pathogenic Mechanisms Involved in Development and Progression of ROS-Associated Diseases
edited by
submission deadline 30 Sep 2026 | Viewed by 194 | Submission Open
Keywords: Reactive Oxygen Species (ROS); oxidative stress; pathogenic mechanisms; disease progression; mitochondrial dysfunction; inflammation and immune regulation; redox biology; molecular signaling pathways; antioxidants and therapeutics; comparative medicine; One Health; translational research
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Innovative Approaches to Rice Crop Production Under Environmental Stresses submission deadline 30 Sep 2026 | Viewed by 186 | Submission Open
Keywords: abiotic stress; environmental stress response; stress adaptation; DNA damage and repair; functional genomics; plant physiology; biofortification
(This special issue belongs to the Section Genetics and Genomics)
Coral Physiological Plasticity and Environmental Adaptation: From Molecular Mechanisms to Ecosystem Resilience submission deadline 30 Sep 2026 | Viewed by 185 | Submission Open
Keywords: environmental stressors; physiological plasticity; climate resilience; molecular mechanisms; coral symbiosis; adaptive potential; ocean acidification; thermal tolerance
(This special issue belongs to the Section Marine and Freshwater Biology)
Metabolic Bases and Pathophysiology Associated with Obesity
edited by Eidy de Oliveira Santos and
submission deadline 30 Sep 2026 | Viewed by 161 | Submission Open
Keywords: obesity; energy metabolism; biomarkers; pathophysiology; chronic inflammation; insulin resistance; adipogenesis; hormonal signaling; cardiometabolic diseases
Pollination Biology: 2nd Edition
edited by and
submission deadline 1 Oct 2026 | 1 articles | Viewed by 1120 | Submission Open
Keywords: conservation biology; insect diversity; pollinator-plant interactions; ecosystem service; pollinating insect; flower; bee
(This special issue belongs to the Section Ecology)
Semaphorins as Drivers of Inflammatory Disease: Setting Immune Cells in Motion
edited by
submission deadline 3 Oct 2026 | Viewed by 231 | Submission Open
Keywords: semaphorins; inflammation; neuronal guidance proteins; soluble guidance cues; cell motility; cytoskeletal dynamics; extracellular matrix
(This special issue belongs to the Section Immunology)
Neural and Glial Aging In Vitro
edited by
submission deadline 15 Oct 2026 | Viewed by 263 | Submission Open
Keywords: neurons; glia; aging; neurodegenerative diseases; morphological changes
(This special issue belongs to the Section Neuroscience)
Immunometabolic and Hormonal Signaling Pathways in Cardiovascular and Metabolic Disorders
edited by Xiangyu Zhang
submission deadline 15 Oct 2026 | Viewed by 182 | Submission Open
Keywords: immunometabolism; immune cells; hormone; signaling pathways; receptors; organ crosstalk; metabolites; cardiovascular diseases; metabolic disorders; pathophysiology; therapy; biomarkers; molecular and cellular biology
(This special issue belongs to the Section Medical Biology)
Multi-omics Approaches in Agricultural Crops to Unravel Responses to Environmental Stresses and Advance Sustainable Agriculture
edited by
submission deadline 30 Oct 2026 | 3 articles | Viewed by 9962 | Submission Open
Keywords: plant functional genomics; environmental stress; climate change; crop yield; crop quality; nutritional properties; omics approaches; genomics; transcriptomics; proteomics; metabolomics; epigenomics; phenomics; stress-tolerant crops; breeding strategies; data integration; systems biology; sustainable agriculture; underutilized crops; orphan crops; beneficial microorganisms
(This special issue belongs to the Section Plant Science)
Pathophysiology of Hearing Loss
edited by Charles E. Bishop
submission deadline 30 Oct 2026 | 2 articles | Viewed by 4230 | Submission Open
Keywords: hearing loss; cochlea; noise; deafness genes; cell death; hair cells; inner ear; biotoxicity; metabolic risk; gene mutation; physiology and pathophysiology; animal models; biomarkers and molecular mechanisms
(This special issue belongs to the Section Physiology)
Diabetes and Cardiovascular Diseases in the New Era
edited by Prashilla Soma and
submission deadline 30 Oct 2026 | 1 articles | Viewed by 2801 | Submission Open
Keywords: metabolic dysregulation; endothelial dysfunction; inflammation; immune response; molecular signaling pathways; oxidative stress and vascular remodeling
(This special issue belongs to the Section Medical Biology)
Molecular, Biophysical, and Neurophysiological Mechanisms Underlying Magnetoreception
edited by and
submission deadline 30 Oct 2026 | 1 articles | Viewed by 1026 | Submission Open
Keywords: earth magnetic field; magnetosensing; magnetite; radical pair; orientation; navigation; magnetic receptor; electroreceptor; neurophysiology
Fatty Acid Metabolism and Inflammation
edited by
submission deadline 30 Oct 2026 | Viewed by 255 | Submission Open
Keywords: fatty acid metabolism; metabolic dysfunction; mitochondrial impairment; oxidative stress; glucose metabolism; lipid metabolism; Immune modulation; Inflammation; biomarkers
(This special issue belongs to the Section Physiology)
Animal Virus–Host Interactions and Cross-Species Dynamics submission deadline 30 Oct 2026 | Viewed by 255 | Submission Open
Keywords: animal viruses; zoonosis; pathogenesis; host immunity; vaccines; antivirals; host– pathogen interaction; One Health; veterinary virology
(This special issue belongs to the Section Infection Biology)
Advances in Zebrafish as an Experimental Model: From Husbandry to Cutting-Edge Applications
edited by Rosario Moyano-Salvago, and
submission deadline 30 Oct 2026 | Viewed by 205 | Submission Open
Keywords: zebrafish; experimental model; developmental biology; genetics; gene editing; transgenesis; toxicology; regeneration; animal welfare; biomedical research
(This special issue belongs to the Section Zoology)
Immunosenescence and Its Modification by Interventions
edited by and Luca Pangrazzi
submission deadline 31 Oct 2026 | 2 articles | Viewed by 11176 | Submission Open
Keywords: immunosenescence; aging immune system; inflammaging; vaccine efficacy in elderly; nutritional immunomodulation; exercise and immunity; senolytic therapies; T-cell exhaustion; thymic rejuvenation; age-related diseases
(This special issue belongs to the Section Immunology)
Mitochondria and Cardiovascular Diseases
edited by Qingxun Hu
submission deadline 31 Oct 2026 | 1 articles | Viewed by 6599 | Submission Open
Keywords: cardiovascular diseases; mitochondria; pathophysiology; cardiology; cell metabolism; animal models; epigenetics; redox biology
(This special issue belongs to the Section Physiology)
Microbial Life at the Extremes: From Environmental Diversity to Functional Insights submission deadline 31 Oct 2026 | 4 articles | Viewed by 5865 | Submission Open
Keywords: extremophiles; microbial diversity; functional adaptation; extreme environment; synthetic extreme environments; biosignatures TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Advances in Plant Multi-Omics
edited by , Zhonglong Guo and Xuekai Wei
submission deadline 31 Oct 2026 | 6 articles | Viewed by 4371 | Submission Open
Keywords: multi-omics integration; plant systems biology; high-throughput sequencing; bioinformatics integration; stress response
(This special issue belongs to the Section Plant Science)
Exploring the Impact of Probiotics and Fermented Food on Gut Microbiota for Personalized Nutrition and Host Health submission deadline 31 Oct 2026 | 1 articles | Viewed by 1509 | Submission Open
Keywords: probiotics (bacteria and yeast); gut microbiota and mycobiome; personalized nutrition; microbiome– host interaction mechanisms; gut– axis communication (brain/skin/immune)
(This special issue belongs to the Section Microbiology)
Transcriptional Regulation in Eukaryotes
edited by Anil Kumar Panigrahi
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1203 | Submission Open
Keywords: transcription factors (TFs); transcriptional coregulators; RNA polymerase II; chromatin modifications and remodeling; enhancers; silencers; non-coding RNAs; 3D chromatin architecture; multi-omics integration; single-cell technologies
(This special issue belongs to the Section Genetics and Genomics)
Brain Organoids: Construction, Analysis, and Application
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1185 | Submission Open
Keywords: brain organoids; iPSCs; neurodevelopmental disorders; region-specific organoids; functional neuronal analysis
Pathogenesis and Immune Evasion of Mycobacteria in Mammals
edited by Federico Carlos Blanco and Cristina Lourdes Vázquez
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1101 | Submission Open
Keywords: mycobacteria; pathogenesis; immune evasion; host– pathogen interactions; latency; zoonotic transmission; comparative immunology; vaccine development; host-directed therapies
(This special issue belongs to the Section Immunology)
Plant Mineral Nutrition: Enhancing Plant Resilience submission deadline 31 Oct 2026 | 1 articles | Viewed by 1095 | Submission Open
Keywords: plant resilience; pest; microbiomes; nutrient use efficiency; soil health; plant physiology; plant stress
(This special issue belongs to the Section Plant Science)
Research Advances on Biology and Genetics of Bees
edited by and
submission deadline 31 Oct 2026 | 1 articles | Viewed by 1001 | Submission Open
Keywords: bee biology; pollination ecology; environmental stressors; bee genomics and omics; bee health and conservation; foraging behavior and social organization
(This special issue belongs to the Section Zoology)
Current Advances in Cancer Genomics
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 968 | Submission Open
Keywords: cancer genomics; tumor heterogeneity; epigenomics; single-cell sequencing; multi-omics; genomic biomarkers; precision oncology; computational genomics; non-coding RNA; drug resistance
(This special issue belongs to the Section Cancer Biology)
Marine Organisms as Powerful Indicators of Climate Change and Human Impact
edited by
submission deadline 31 Oct 2026 | 1 articles | Viewed by 916 | Submission Open
Keywords: marine organisms; climate changes; biological indicators; invasive species; human impact; ecological modifications; anthropogenic pollution; marine biodiversity
(This special issue belongs to the Section Marine and Freshwater Biology)
Genetic Biomarkers of Innate Immunity and Lipid Metabolism in Cardiovascular Disease submission deadline 31 Oct 2026 | 1 articles | Viewed by 751 | Submission Open
Keywords: epigenetics; gene expression; inflammation; vascular calcification; immune cells; atherosclerosis; genetic variation; plasma lipid concentrations
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Feature Papers in Marine and Freshwater Biology
edited by
submission deadline 31 Oct 2026 | Viewed by 296 | Submission Open
Keywords: aquatic ecology; aquatic physiology; aquatic ecosystems; aquatic species adaptation and evolution; aquatic biodiversity; aquatic mammals; aquatic top predators; aquatic invertebrates; aquatic symbioses; aquatic genetics; aquatic microbiology; limnology; biological oceanography; aquatic conservation; protection; and sustainable exploitation
(This special issue belongs to the Section Marine and Freshwater Biology)
Decoding RNA Modifications in Cancer Biology
edited by Yutao Zhao
submission deadline 31 Oct 2026 | Viewed by 296 | Submission Open
Keywords: RNA modifications; epitranscriptomics; gene regulation; RNA biology; post-transcriptional regulation; N6-methyladenosine (m6A); pseudouridine (Ψ )
(This special issue belongs to the Section Cancer Biology)
Molecular Mechanisms of AHPND: From Pathogen Virulence to Host Immunity submission deadline 31 Oct 2026 | Viewed by 168 | Submission Open
Keywords: AHPND; Vibrio; pathogenesis; host immunity; shrimp disease; aquaculture; virulence mechanisms; omics
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Depression: From Genetic and Biochemical Factors to Behavioral Activation and Psychological Processes submission deadline 31 Oct 2026 | Viewed by 155 | Submission Open
Keywords: depression; epigenetics; serotonin; dopamine; behavioral neuroscience
(This special issue belongs to the Section Neuroscience)
Reproduction Under the Microscope: From Oocyte Architecture to Reproductive Function
edited by
submission deadline 1 Nov 2026 | Viewed by 226 | Submission Open
Keywords: reproductive biology; oocyte; gametogenesis; fertilization; embryonic development; electron microscopy; ultrastructure; reproductive pathology
Genetics and Evolutionary Biology of Aquatic Organisms
edited by and Liang Guo
submission deadline 15 Nov 2026 | 5 articles | Viewed by 6043 | Submission Open
Keywords: population genetics; conservation genetics; biodiversity; comparative genomics; polyploidization; rapid adaptation; population genetic divergence; thermal tolerance; hypoxia adaptation; deep-sea pressure adaptation; convergent evolution; molecular clock; phylogeography; population genetic structure; divergence time; inbreeding depression; genetic diversity; genomic selection; genome assembly; transcriptomics; population genomics
(This special issue belongs to the Section Evolutionary Biology)
Erythrocytes in Human Life—Functions Beyond Oxygen Transport
edited by and
submission deadline 15 Nov 2026 | 1 articles | Viewed by 650 | Submission Open
Keywords: erythrocytes in physiological processes; erythrocytes in disease pathophysiology; erythrocyte biomechanics; erythrocyte imaging; erythrocyte membrane; erythrocyte metabolism; haemoglobin; immune modulation; redox homeostasis
(This special issue belongs to the Section Cell Biology)
Regulatory Mechanisms of Plant Stress Response
edited by and Li Ren
submission deadline 30 Nov 2026 | 3 articles | Viewed by 8072 | Submission Open
Keywords: gene; gene expression; gene function; molecular regulation; genetic resource; phenotype; stress response
(This special issue belongs to the Section Genetics and Genomics)
Physiology and Pathophysiology of the Kidney
edited by Gang Liu
submission deadline 30 Nov 2026 | 4 articles | Viewed by 8018 | Submission Open
Keywords: renal physiology; renal hemodynamics; kidney injury; regenerative therapies; urology
(This special issue belongs to the Section Physiology)
Impact of Climate Change on Structural and Functional Characteristics of Freshwater Ecosystems and Its Implications for Their Resources’ Management submission deadline 30 Nov 2026 | 1 articles | Viewed by 4503 | Submission Open
Keywords: AI applications; biodiversity; biological assemblages; climate change; ecological resilience; ecosystem ser-vices; freshwater ecosystems; nutrient cycling; temperature
(This special issue belongs to the Section Ecology)
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