Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gene Editing and Genetic Regulation: New Insight in Insect Sex Determination, Reproductive Development and Pest Control
edited by Honglun Bi
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1168 | Submission Open
Keywords: insect gene editing; genetic regulation  ; CRISPR/Cas  ; gene drive  ; pest control; sex determination  ; reproductive development; insect sterile technique
(This special issue belongs to the Section Zoology)
Airway Smooth Muscle and Respiratory Diseases
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 1038 | Submission Open
Keywords: airway; airway smooth muscle; asthma; COPD; airway hyperresponsiveness; airway inflammation; airway remodeling; bronchospasm; bronchodilators
(This special issue belongs to the Section Cell Biology)
Adaptation Mechanisms of Forest Trees to Abiotic Stress
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 877 | Submission Open
Keywords: genetic variation; epigenetic control; plant hormone; nitric oxide; reactive oxygen species; phenomic; metabolomic; genomic; signal transduction; gene function
(This special issue belongs to the Section Plant Science)
Recent Advances in Metabolic Disorders
edited by
submission deadline 31 Aug 2025 | 1 articles | Viewed by 831 | Submission Open
Keywords: iron; mitochondria; oxidative stress; inflammation; metabolism; free radicals; alcohol; treatment   TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Physiology)
Disease Biomarker Discovery and Validation
edited by Matthew James Jennings
submission deadline 31 Aug 2025 | 1 articles | Viewed by 792 | Submission Open
Keywords: biomarkers; prognostic validation; predictive validation; analytical validation
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Redox Signaling and Oxidative Stress in Health and Disease
edited by and
submission deadline 31 Aug 2025 | 1 articles | Viewed by 735 | Submission Open
Keywords: redox signaling; oxidative stress; antioxidant defense; cellular regulation; aging; cancer; cardiovascular diseases; neurodegenerative diseases; therapeutic approaches; digital biotechnology
(This special issue belongs to the Section Cell Biology)
Regenerative Biology: Regeneration After Spinal Cord and Peripheral Nerve Injury submission deadline 31 Aug 2025 | 1 articles | Viewed by 729 | Submission Open
Keywords: neuronal regeneration; peripheral nerve repair; spinal cord injury; axonal growth; neuroplasticity; glial cells; molecular signaling pathways; stem cells in nerve regeneration; neuroinflammation; animal models of nerve injury
(This special issue belongs to the Section Neuroscience)
Impact of Climate Change on Structural and Functional Characteristics of Freshwater Ecosystems and Its Implications for Their Resources’ Management submission deadline 31 Aug 2025 | 1 articles | Viewed by 686 | Submission Open
Keywords: AI applications; biodiversity; biological assemblages; climate change; ecological resilience; ecosystem ser-vices; freshwater ecosystems; nutrient cycling; temperature
(This special issue belongs to the Section Ecology)
Molecular and Neurological Aspects of Sensory Processing Disorders submission deadline 31 Aug 2025 | Viewed by 398 | Submission Open
Keywords: sensory processing; sensory processing disorders; SPDs; sensory stimuli; brain activity; genetic; functional neuroimaging studies
(This special issue belongs to the Section Neuroscience)
The Role of Lipids in Cardiovascular and Neurodegenerative Diseases
edited by , and Yaxin Li
submission deadline 31 Aug 2025 | Viewed by 319 | Submission Open
Keywords: lipid biology; lipid peroxidation; lipidomics; lipid foods or nutrients; cardiovascular disease; neurodegenerative diseases
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Cellular and Molecular Biology of Liver Diseases
edited by Matthew McMillin
submission deadline 31 Aug 2025 | Viewed by 315 | Submission Open
Keywords: drug-induced liver injury; cholestasis; hepatitis; metabolic dysfunction-associated steatotic liver disease; alcohol-associated liver disease
(This special issue belongs to the Section Cell Biology)
Machine Learning in Pathogen Discovery
edited by
submission deadline 31 Aug 2025 | Viewed by 286 | Submission Open
Keywords: pathogen; machine learning; disease; antibiotic; virulence
(This special issue belongs to the Section Bioinformatics)
The Maternal Microbiome and Metabolome: Recent Advances submission deadline 31 Aug 2025 | Viewed by 246 | Submission Open
Keywords: maternal microbiome; metabolome; pregnancy outcomes; fetal development; biomarkers; immune function; metabolic health; disease prediction; therapeutic interventions; maternal and child health
(This special issue belongs to the Section Developmental and Reproductive Biology)
Biomarkers for Cancer Immunity
edited by Xuyao Zhang
submission deadline 31 Aug 2025 | Viewed by 245 | Submission Open
Keywords: tumor microenvironment; tumor immunity; systems immunology; resistance mechanism; biomarkers
Intermolecular Interactions in Cytochrome P450 Systems
edited by and John Hackett
submission deadline 31 Aug 2025 | Viewed by 210 | Submission Open
Keywords: cytochrome P450; NADPH-cytochrome P450 reductase; cytochrome b5; adrenodoxin; microsomes; protein– protein interactions; protein-lipid interactions; systems biochemistry of drug metabolism; cytochrome P450-dependent signaling
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Effects of Aquatic Sediments on Marine Ecosystems
edited by Ehui Tan and Sibo Zhang
submission deadline 31 Aug 2025 | Viewed by 198 | Submission Open
Keywords: biogeochemical cycling processes; microbial activity; sediment– water interface; benthic organisms; pollutants; global change; nutrients; environmental issues
(This special issue belongs to the Section Ecology)
The Regulation of Glucose Homeostasis
edited by Aaron Aykut Uner
submission deadline 31 Aug 2025 | Viewed by 190 | Submission Open
Keywords: glucose homeostasis; brain; type 1 diabetes; type 2 diabetes; insulin sensitivity; beta-cell regeneration
(This special issue belongs to the Section Physiology)
Biological Advances in Pluripotent Stem Cells
edited by and Matthias Jung
submission deadline 31 Aug 2025 | Viewed by 172 | Submission Open
Keywords: induced pluripotent stem cell; embryonic stem cell; regenerative medicine; drug research; organoid; translational biology
(This special issue belongs to the Section Cell Biology)
Biosynthesis of Metabolites from Microorganisms, or Microorganism-Host Interaction? (Volume II) submission deadline 1 Sep 2025 | 5 articles | Viewed by 11841 | Submission Open
Keywords: biosynthesis; biological activity; biosynthesis regulation; microbial metabolites; microbe– host reaction
(This special issue belongs to the Section Microbiology)
Viral Infections in Animals: Pathogenesis and Immunity
edited by
submission deadline 1 Sep 2025 | Viewed by 102 | Submission Open
Keywords: virus– host interactions; antiviral immunity; mechanisms of viral pathogenesis
(This special issue belongs to the Section Immunology)
Feature Review Papers on Developmental Biology
edited by
submission deadline 15 Sep 2025 | 6 articles | Viewed by 11321 | Submission Open
Keywords: embryo/fetus development; differentiation; growth; homeostasis; regeneration; aging; cell cycle regulation; stem cells; organoids
(This special issue belongs to the Section Developmental and Reproductive Biology)
Biological Rhythms and Molecular Clockworks in Physiology and Pathology submission deadline 30 Sep 2025 | 10 articles | Viewed by 27276 | Submission Open
Keywords: biological rhythms; molecular clockworks; circadian timing system; circadian desynchrony; circadian disruption; chronopathology; chronopharmacology and chronotherapeutics; chronomedicine
(This special issue belongs to the Section Physiology)
Plant Breeding: From Biology to Biotechnology
edited by Juwu Gong
submission deadline 30 Sep 2025 | 5 articles | Viewed by 4826 | Submission Open
Keywords: plant breeding; biotechnology; molecular marker-assisted selection; genetic engineering; genome editing; tissue culture; phenotype; genetics; omics
(This special issue belongs to the Section Biotechnology)
Artificial Intelligence Research for Complex Biological Systems submission deadline 30 Sep 2025 | 4 articles | Viewed by 4339 | Submission Open
Keywords: deep learning; generative artificial intelligence; bioinformatics; complex biological systems; cancer; neuroscience; next-generation sequencing; single-cell and bulk omics; genomics
(This special issue belongs to the Section Bioinformatics)
Molecular Basis of Bone Homeostasis and Skeletal Diseases
edited by
submission deadline 30 Sep 2025 | 3 articles | Viewed by 4193 | Submission Open
Keywords: osteoclast; osteoblast; bone; skeletal disease; bone formation; bone resorption; osteoporosis; osteopetrosis; human genetics; mouse genetics
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Research Advancements in Oral Biology
edited by and Nina Petrović
submission deadline 30 Sep 2025 | 1 articles | Viewed by 1419 | Submission Open
Keywords: oral biology; oral tissue regeneration; artificial intelligence (AI) in dentistry; genomics and proteomics in dentistry; dental research; salivary diagnostics
(This special issue belongs to the Section Medical Biology)
Research Progress on Melanocytes and Melanin
edited by Zeina Tannous
submission deadline 30 Sep 2025 | Viewed by 342 | Submission Open
Keywords: melanin; melanocytes; melanocyte stem cell; pigmentation; melanoma; dysplastic nevi; vitiligo; melasma
(This special issue belongs to the Section Medical Biology)
Molecular Mechanisms of Cell Signal Transduction
edited by Wenjing Zhang
submission deadline 30 Sep 2025 | Viewed by 221 | Submission Open
Keywords: molecular interactions in signaling; phosphorylation and signal propagation; post-translational modifications; cross-talk between signaling pathways; cellular response to extracellular stimuli; metabolic regulation and signaling; signaling in cancer progression; inflammatory signaling pathways; role of signaling in stem cell differentiation; innovative imaging techniques for signaling
(This special issue belongs to the Section Cell Biology)
The Role of Innate Immunity in Organ Transplantation
edited by Todd V. Brennan
submission deadline 30 Sep 2025 | Viewed by 209 | Submission Open
Keywords: innate immunity; allograft rejection; transplantation; immune tolerance
(This special issue belongs to the Section Medical Biology)
Island Ecology and Biodiversity: Managing the Effects of Climate and Land-Use Change
edited by Kealohanuiopuna Mark Kinney and Susan Cordell
submission deadline 30 Sep 2025 | Viewed by 207 | Submission Open
Keywords: island biogeography; biodiversity conservation; invasive species management; biocultural approaches; ecosystem resilience; landscape ecology; environmental sustainability; climate adaptation; social– ecological systems; restoration ecology       TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in English   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate English to Simplified Chinese Never translate English Never translate admin.mdpi.com
(This special issue belongs to the Section Ecology)
Physiology and Ecology of Animal Parasites and Related Diseases
edited by Marcela K. Castelo
submission deadline 30 Sep 2025 | Viewed by 196 | Submission Open
Keywords: parasites; parasitoids; physiology; ecology; ecophysiology; diseases; global change
(This special issue belongs to the Section Zoology)
Metabolic Interactions between the Gut Microbiome and Host
edited by and
submission deadline 30 Oct 2025 | 5 articles | Viewed by 8815 | Submission Open
Keywords: gut microbiome; host; metabolome; microbial heterogeneity; biomolecules
(This special issue belongs to the Section Microbiology)
Multi-omics Approaches in Agricultural Crops to Unravel Responses to Environmental Stresses and Advance Sustainable Agriculture
edited by
submission deadline 30 Oct 2025 | 1 articles | Viewed by 1695 | Submission Open
Keywords: plant functional genomics; environmental stress; climate change; crop yield; crop quality; nutritional properties; omics approaches; genomics; transcriptomics; proteomics; metabolomics; epigenomics; phenomics; stress-tolerant crops; breeding strategies; data integration; systems biology; sustainable agriculture; underutilized crops; orphan crops; beneficial microorganisms
(This special issue belongs to the Section Plant Science)
Pathophysiology of Hearing Loss
edited by Charles E. Bishop
submission deadline 30 Oct 2025 | Viewed by 197 | Submission Open
Keywords: hearing loss; cochlea; noise; deafness genes; cell death; hair cells; inner ear; biotoxicity; metabolic risk; gene mutation; physiology and pathophysiology; animal models; biomarkers and molecular mechanisms
(This special issue belongs to the Section Physiology)
Advances in the Fields of Neurotrauma and Neuroregeneration submission deadline 31 Oct 2025 | 6 articles | Viewed by 37699 | Submission Open
Keywords: neurotrauma; spinal cord injury; traumatic brain injury; neuropathic pain; neuroinflammation; axonal regeneration; postinjury plasticity; neurorehabilitation; cell transplantation
(This special issue belongs to the Section Neuroscience)
Young Researchers in Neuroscience
edited by Yansheng Du
submission deadline 31 Oct 2025 | 2 articles | Viewed by 11020 | Submission Open
Keywords: neurobiology; cell biology; molecular mechanisms; neural development; synaptic function; ion channels; neurotransmitter systems; gene expression; neuronal signaling; cellular physiology
(This special issue belongs to the Section Neuroscience)
Immunosenescence and Its Modification by Interventions
edited by and Luca Pangrazzi
submission deadline 31 Oct 2025 | 1 articles | Viewed by 3495 | Submission Open
Keywords: immunosenescence; aging immune system; inflammaging; vaccine efficacy in elderly; nutritional immunomodulation; exercise and immunity; senolytic therapies; T-cell exhaustion; thymic rejuvenation; age-related diseases
(This special issue belongs to the Section Immunology)
Pathogen-Host Interaction and Vaccine/Drug Design
edited by Iga Kucharska
submission deadline 31 Oct 2025 | 1 articles | Viewed by 2189 | Submission Open
Keywords: infectious diseases; host– pathogen interactions; vaccine; drug design; immune evasion; immunogen
(This special issue belongs to the Section Medical Biology)
Progress in Wildlife Conservation, Management and Biological Research
edited by Ana Carolina Srbek-Araujo
submission deadline 31 Oct 2025 | 2 articles | Viewed by 1770 | Submission Open
Keywords: adaptive capacity; climate change; conservation opportunities; species vulnerability; threatened species; wildlife conservation; wildlife management
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Advances in Omics Approaches for Understanding Metabolic Disorders: Environmental and Nutritional Perspectives
edited by Yue Ge
submission deadline 31 Oct 2025 | 1 articles | Viewed by 890 | Submission Open
Keywords: metabolic disorders; environmental exposures; nutritional factors; omics technologies; co-exposures; cumulative toxicity; metabolic pathways; human health risk assessment; advanced in vitro models; systems toxicology
(This special issue belongs to the Section Physiology)
Extracellular Vesicles: Biogenesis and Functions in the Complex Landscape of Differentiation and Disease
edited by
submission deadline 31 Oct 2025 | Viewed by 424 | Submission Open
Keywords: stem cell biology; stem cell differentiation; adipogenesis; neurogenesis; extracellular vesicles in stem cell differentiation; ncRNAs; tumor microenvironment; intercellular communication
(This special issue belongs to the Section Cell Biology)
Advancing Crop Nutritional Quality Through Genomic Approaches
edited by Gen Xu
submission deadline 31 Oct 2025 | 1 articles | Viewed by 423 | Submission Open
Keywords: crop improvement; genomics; multi-omics; genetic loci; breeding
(This special issue belongs to the Section Plant Science)
Plant-Microbe Interaction: The Cellular Mechanism Influence Plant Health
edited by and Gongjun Shi
submission deadline 31 Oct 2025 | Viewed by 329 | Submission Open
Keywords: plant-microbe interaction; plant health; plant immunity; gene-for-gene model; resistosomes; metabolic crosstalk; climate change
Transcriptional Regulation in Eukaryotes
edited by Anil Kumar Panigrahi
submission deadline 31 Oct 2025 | Viewed by 309 | Submission Open
Keywords: transcription factors (TFs); transcriptional coregulators; RNA polymerase II; chromatin modifications and remodeling; enhancers; silencers; non-coding RNAs; 3D chromatin architecture; multi-omics integration; single-cell technologies
(This special issue belongs to the Section Genetics and Genomics)
Mechanisms of Drug Resistance in Cancer Cells
edited by , and
submission deadline 31 Oct 2025 | Viewed by 256 | Submission Open
Keywords: drug resistance; mechanisms; cell growth; cell proliferation; efficacy
(This special issue belongs to the Section Medical Biology)
Advancing Molecular Mechanisms and Therapeutic Innovations in Neurodegenerative Diseases
edited by Tao Yang
submission deadline 31 Oct 2025 | Viewed by 145 | Submission Open
Keywords: neurodegenerative diseases; Alzheimer's disease; amyotrophic lateral sclerosis; Parkinson's disease; Huntington's disease; frontotemporal dementia; small molecules; synaptic dysfunction; neuroinflammation; biomarkers
(This special issue belongs to the Section Neuroscience)
DNA Repair and DNA Damage Response (DDR) in Oncology
edited by
submission deadline 31 Oct 2025 | Viewed by 126 | Submission Open
Keywords: DNA repair and DNA damage response pathways; cancer target therapy; DNA replication stress response in genome stability; oxidative stress response and redox regulation; DNA single-strand break repair and signaling
(This special issue belongs to the Section Cancer Biology)
Mitochondria and Cardiovascular Diseases
edited by Qingxun Hu
submission deadline 31 Oct 2025 | Viewed by 110 | Submission Open
Keywords: cardiovascular diseases; mitochondria; pathophysiology; cardiology; cell metabolism; animal models; epigenetics; redox biology
(This special issue belongs to the Section Physiology)
2nd Edition: Conservation and Evolution of Wildlife in the Context of Climate Change and Human Population Growth
edited by
submission deadline 1 Nov 2025 | 1 articles | Viewed by 591 | Submission Open
Keywords: changes; local temperature; adaptation; evolution; animals; plants
(This special issue belongs to the Section Behavioural Biology)
Lysosomes and Diseases Associated with Its Dysfunction submission deadline 15 Nov 2025 | 4 articles | Viewed by 16736 | Submission Open
Keywords: activities; mutations; endocytosis; autophagy; metabolism; proteins
(This special issue belongs to the Section Cell Biology)
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