Special Issues

Biology publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Editorial Board Members’ Collection Series: The Dynamics of RNA–Protein Interactions
edited by and
submission deadline 31 Mar 2025 | 3 articles | Viewed by 4133 | Submission Open
Keywords: RNA-binding proteins; mRNA splicing; mRNA decay; mRNA translation; RNA localization; microRNAs; siRNAs; long noncoding RNAs; phase separation; RNA granules; membraneless organelles
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Advances in Biological Breast Cancer Research
edited by Anna Mart Engelbrecht, and
submission deadline 31 Mar 2025 | 1 articles | Viewed by 2243 | Submission Open
Keywords: breast cancer; breast tumor; breast cancer cells; animal models; cell death; cancer diagnosis; cancer treatment; biomarkers; cancer microenvironment; carcinogens; estrogen receptor; molecular biology; cell biology
(This special issue belongs to the Section Cancer Biology)
Pathophysiology of Testis
edited by María Susana Theas, and María Noel Galardo
submission deadline 31 Mar 2025 | 1 articles | Viewed by 1202 | Submission Open
Keywords: testis; infertility; aging; inflammation; spermatogenesis; steroidogenesis; energy balance
(This special issue belongs to the Section Physiology)
Circular RNA Biology and Roles in Diseases
edited by Nan Wu and
submission deadline 31 Mar 2025 | 1 articles | Viewed by 682 | Submission Open
Keywords: RNA biology; diseases; circRNAs
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Physiology of Lymph Vessels: Structure, Function and Modelling (Volume II)
edited by
submission deadline 31 Mar 2025 | Viewed by 327 | Submission Open
Keywords: lymphatic vessel; oedema; lymphatic muscle; spontaneous contractions; functional imaging; translational medicine; intrinsic pumping; extrinsic pumping; fluid homeostasis; numerical modelling
(This special issue belongs to the Section Physiology)
Genetic Mechanisms in Archaea submission deadline 31 Mar 2025 | Viewed by 318 | Submission Open
Keywords: archaea; extrachromosomal genetic elements; chromosome structure; DNA replication; DNA repair; DNA recombination; transcription regulation; epigenetic regulation         TRANSLATE with x English Arabic Hebrew Polish Bulgarian Hindi Portuguese Catalan Hmong Daw Romanian Chinese Simplified Hungarian Russian Chinese Traditional Indonesian Slovak Czech Italian Slovenian Danish Japanese Spanish Dutch Klingon Swedish English Korean Thai Estonian Latvian Turkish Finnish Lithuanian Ukrainian French Malay Urdu German Maltese Vietnamese Greek Norwegian Welsh Haitian Creole Persian   //   TRANSLATE with COPY THE URL BELOW Back EMBED THE SNIPPET BELOW IN YOUR SITE Enable collaborative features and customize widget: Bing Webmaster Portal Back //     This page is in French   Translate to Simplified Chinese         Afrikaans Albanian Amharic Arabic Armenian Azerbaijani Bengali Bulgarian Catalan Croatian Czech Danish Dutch English Estonian Finnish French German Greek Gujarati Haitian Creole Hebrew Hindi Hungarian Icelandic Indonesian Italian Japanese Kannada Kazakh Khmer Korean Kurdish (Kurmanji) Lao Latvian Lithuanian Malagasy Malay Malayalam Maltese Maori Marathi Myanmar (Burmese) Nepali Norwegian Pashto Persian Polish Portuguese Punjabi Romanian Russian Samoan Simplified Chinese Slovak Slovenian Spanish Swedish Tamil Telugu Thai Traditional Chinese Turkish Ukrainian Urdu Vietnamese Welsh   Always translate French to Simplified Chinese Never translate French Never translate admin.mdpi.com
(This special issue belongs to the Section Microbiology)
The Emerging Role of Mitochondria in Neurobiology submission deadline 31 Mar 2025 | Viewed by 139 | Submission Open
Keywords: mitochondrial dynamics; neurodegenerative diseases; neuronal bioenergetics; synaptic function; neurogenesis; neuronal plasticity
(This special issue belongs to the Section Neuroscience)
Extracellular Vesicles: Biogenesis and Functions in the Complex Landscape of Differentiation and Disease
edited by
submission deadline 31 Mar 2025 | Viewed by 106 | Submission Open
Keywords: stem cell biology; stem cell differentiation; adipogenesis; neurogenesis; extracellular vesicles in stem cell differentiation; ncRNAs; tumor microenvironment; intercellular communication
(This special issue belongs to the Section Cell Biology)
Innate Immunity and Inflammatory Diseases
edited by Veera Ganesh Yerra, Santosh Reddy Sukka and Anil Kumar Kalvala
submission deadline 31 Mar 2025 | Viewed by 101 | Submission Open
Keywords: innate immunity; inflammation; immunotherapy; immune cells; inflammatory diseases
(This special issue belongs to the Section Immunology)
Artificial Intelligence Research for Complex Biological Systems
edited by and Milana Frenkel-Morgenstern
submission deadline 31 Mar 2025 | Viewed by 61 | Submission Open
Keywords: deep learning; generative artificial intelligence; bioinformatics; complex biological systems; cancer; neuroscience; next-generation sequencing; single-cell and bulk omics; genomics
(This special issue belongs to the Section Bioinformatics)
Neurobiology of Traumatic Brain Injury
edited by and Dimitrios A. Kazis
submission deadline 31 Mar 2025 | Viewed by 35 | Submission Open
Keywords: traumatic brain injury (TBI); neuroinflammation; neuroplasticity; neurodegeneration; molecular pathways; genetic factors; diagnostic tools; therapeutic strategies; rehabilitation techniques; chronic neurological conditions
(This special issue belongs to the Section Neuroscience)
Gene–Environment Interactions in Evolutionary Developmental Biology
edited by Alexander Shingleton
submission deadline 31 Mar 2025 | Viewed by 28 | Submission Open
Keywords: phenotypic plasticity; gene– environment interactions; genetic architecture of plasticity; mechanisms of phenotypic variation; anthropogenic stressors; evolution of plastic responses
(This special issue belongs to the Section Evolutionary Biology)
Proteomics and Human Diseases
edited by Lei Fang
submission deadline 31 Mar 2025 | Viewed by 8 | Submission Open
Keywords: proteomics; clinical proteomics; human diseases; biomarker identification; therapeutic target; molecular mechanism; cancers; metabolic diseases; cardiovascular diseases; neurodegeneration diseases
(This special issue belongs to the Section Medical Biology)
Mitochondria: The Signaling Organelle
edited by
submission deadline 15 Apr 2025 | 1 articles | Viewed by 1536 | Submission Open
Keywords: mitochondria; signal transduction; homeostasis; metabolism; apoptosis; redox biology; organelle communication
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Bird Biology and Conservation submission deadline 15 Apr 2025 | Viewed by 23 | Submission Open
Keywords: avian conservation; ecological modeling; GIS; spatial ecology; telemetry
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Multi-omics Data Integration in Complex Diseases submission deadline 30 Apr 2025 | 9 articles | Viewed by 23404 | Submission Open
Keywords: omics; disease; data integration; bioinformatics; genome
(This special issue belongs to the Section Bioinformatics)
Effects of Heavy Metals and Microplastics on Wetland Biodiversity and Ecosystem Function
edited by Hualong Hong and Mohammad Belal Hossain
submission deadline 30 Apr 2025 | 1 articles | Viewed by 3818 | Submission Open
Keywords: heavy metals; microplastics; wetland ecosystems; ecology; risk assessment; food chain; health risk; emerging contaminants; water and sediment contamination; ecosystem health; exposure; polythelene
(This special issue belongs to the Section Ecology)
Biology, Ecology, Management and Conservation of Canidae
edited by Alberto Meriggi and
submission deadline 30 Apr 2025 | 3 articles | Viewed by 2886 | Submission Open
Keywords: Canidae; biology; ecology; management; conservation; ecosystem; habitats; niches; biodiversity; physiology; reproduction
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Neurogenetics of Behaviour submission deadline 30 Apr 2025 | 1 articles | Viewed by 2651 | Submission Open
Keywords: behaviour; genetics; molecules; species; brain; networks; health; disease
(This special issue belongs to the Section Genetics and Genomics)
Application of Metabolomics and Integrated Computing in Chemical Biology
edited by
submission deadline 30 Apr 2025 | 1 articles | Viewed by 2059 | Submission Open
Keywords: chemical biology; computational biology; metabolomics; computational modeling; new chemical entities (NCE); active pharmaceutical ingredients (API); characterization; metabolite profiling
Gut Immunity, Inflammation, and Allergy
edited by
submission deadline 30 Apr 2025 | 2 articles | Viewed by 1976 | Submission Open
Keywords: gut immunity; inflammation; allergy; nutrients; therapeutic agents; molecular biology
(This special issue belongs to the Section Immunology)
Physiology and Pathophysiology of Obesity
edited by Yifei Kang
submission deadline 30 Apr 2025 | 2 articles | Viewed by 771 | Submission Open
Keywords: dietary intervention; alternative food; food supplementation; weight loss; weight management; obesity comorbidities; obesity pathophysiology
(This special issue belongs to the Section Physiology)
The Expression and/or Role of Glycoconjugates in Physiological and Pathological Conditions submission deadline 30 Apr 2025 | Viewed by 655 | Submission Open
Keywords: glycobiology; glycoproteins; glycolipids; glycosyltransferases; glycoconjugates
AI Deep Learning Approach to Study Biological Questions (2nd Edition) submission deadline 30 Apr 2025 | Viewed by 107 | Submission Open
Keywords: OpenCV; Mask RCNN; YOLO; U-Net; StarDist; ImageJ; MATLAB; image segmentation; image classification; locomotion trajectory analysis; volumetric prediction; plants; animals; protozoa; invertebrates; animal behavior; developmental biology; toxicology; zebrafish; medaka; daphnia
Computational Modeling of Drug Delivery
edited by and Arezoo M. Ardekani
submission deadline 30 Apr 2025 | Viewed by 45 | Submission Open
Keywords: computational modeling; drug delivery; computational fluid dynamics; biofluids; quantitative biotransport; mathematical models; artificial intelligence
(This special issue belongs to the Section Biophysics)
Machine Learning Applications in Biology—2nd Edition submission deadline 30 Apr 2025 | Viewed by 24 | Submission Open
Keywords: machine learning; genomics; epigenomics; genetic variation and the environment; gene regulatory networks; integration of multipurpose NGS data
(This special issue belongs to the Section Bioinformatics)
Zoonotic Diseases submission deadline 30 Apr 2025 | Viewed by 19 | Submission Open
Keywords: zoonoses; zoonotic agents; bacteria; viruses; fungi; protozoa; helminths
(This special issue belongs to the Section Infection Biology)
The Impact of Climate Change on Quality, Yield, and Nutritional Properties of Cereals, Legumes, and Oilseeds
edited by Vito Butardo
submission deadline 1 May 2025 | Viewed by 111 | Submission Open
Keywords: climate change; cereals; legumes; oilseeds; grain quality; seed nutrition; yield; elevated temperatures; drought; salinity; atmospheric CO2; multi-omics; field trials; crop modelling; data integration; climate resilience; breed-ing strategies; agronomic practices; beneficial microorganisms; underutilised crops; orphan crops
(This special issue belongs to the Section Plant Science)
Internal Defense System and Evolution of Aquatic Animals
edited by
submission deadline 15 May 2025 | 1 articles | Viewed by 833 | Submission Open
Keywords: internal defense system; evolution; aquatic animals; immunology; aquatic environment; biodiversity; pollution; ecosystems
(This special issue belongs to the Section Evolutionary Biology)
Role of the Human Gut Microbiota in Health and Disease
edited by Jerome Gay-Quéheillard
submission deadline 21 May 2025 | Viewed by 23 | Submission Open
Keywords: microbiota; dysbiosis; gut epithelial barrier; IBD; brain– gut axis; obesity; anxiety; depression; immune system; prebiotics; probiotics
Biology, Ecology and Management of Aquatic Macrophytes
edited by , Shuang Zhao and
submission deadline 31 May 2025 | 3 articles | Viewed by 2047 | Submission Open
Keywords: aquatic macrophytes; ecological planning and management; harmful algal blooms and control; biological resources and environment; mangrove forest; ecological restoration; biodiversity; plant physiology; water security
(This special issue belongs to the Section Plant Science)
Mechanisms Underlying Neuronal Network Activity
edited by Jorge Flores-Hernandez
submission deadline 31 May 2025 | Viewed by 555 | Submission Open
Keywords: neurons; brain circuits; NMDA receptors; acetylcholine; excitability; Parkinson’ s; schizophrenia; learning; attention
(This special issue belongs to the Section Neuroscience)
Understanding and Targeting Biological Mechanisms of Heart Failure (2nd Edition)
edited by and
submission deadline 31 May 2025 | Viewed by 276 | Submission Open
Keywords: developmental biology; genetics; stem cells; heart failure; cell therapy
(This special issue belongs to the Section Biochemistry and Molecular Biology)
Genetic Variability within and between Populations
edited by
submission deadline 31 May 2025 | Viewed by 253 | Submission Open
Keywords: genetic structure; population differentiation; FST or fixation index; migration; gene flow; admixture; heterozygosity; inbreeding; coalescence time; allele frequency; random mating
(This special issue belongs to the Section Evolutionary Biology)
Aquatic Animal Nutrition and Feed
edited by Yun Wang
submission deadline 31 May 2025 | Viewed by 122 | Submission Open
Keywords: aquaculture; aquatic animals; nutrition; aquatic feed; immunity; metabolism
Exposure to Heavy Metals: Advances in Cytotoxicity and Genotoxicity
edited by Qianru Chi
submission deadline 31 May 2025 | Viewed by 102 | Submission Open
Keywords: heavy metal pollutants; exposure assessment; toxic mechanism; biomarkers; metabolomics; environmental quality monitoring; bioinformatics analysis methods
(This special issue belongs to the Section Toxicology)
Repair and Regeneration of Skeletal Muscle
edited by Huili Tong
submission deadline 31 May 2025 | Viewed by 69 | Submission Open
Keywords: skeletal muscle; sarcopenia; atrophy; muscle satellite cells; regeneration and repair
(This special issue belongs to the Section Developmental Biology)
From Conception to Birth: Embryonic Development and Disease
edited by , Soultana Meditskou and
submission deadline 31 May 2025 | Viewed by 63 | Submission Open
Keywords: embryology; organogenesis; cell differentiation; gametes; reproduction; sex ratio; birth defects; pathophysiology; disease
(This special issue belongs to the Section Reproductive Biology)
Cotton: Genomics, Biotechnology and Molecular Breeding
edited by
submission deadline 31 May 2025 | Viewed by 62 | Submission Open
Keywords: cotton; genomics; functional genomics; biotechnology; germplasm; QTL mapping; molecular breeding
(This special issue belongs to the Section Plant Science)
Animal Models of Retinal Degenerative Diseases
edited by Elliot H. Choi and Marco Bassetto
submission deadline 31 May 2025 | Viewed by 60 | Submission Open
Keywords: retinal degeneration; inherited retinal diseases; retina; retinal pigment epithelium; animal models; photoreceptors; retinal ganglion cells; choroid; neovascularization
(This special issue belongs to the Section Neuroscience)
Understanding Syncope: Multidisciplinary Approaches to Diagnosis and Management
edited by and Laranjo Sergio
submission deadline 31 May 2025 | Viewed by 34 | Submission Open
Keywords: syncope; diagnostic strategies; prognostication; treatment options; quality of life; wearable devices; artificial intelligence; autonomic dysfunction; orthostatic hypotension; POTS (postural orthostatic tachycardia syndrome)
(This special issue belongs to the Section Neuroscience)
From the Eye to the Brain: Current Progress in Elucidating the Neural Circuit Dynamics Underlying Visual Processing
edited by Manuel Gomez-Ramirez
submission deadline 31 May 2025 | Viewed by 27 | Submission Open
Keywords: calcium imaging; optogenetics; ultrasound; 2-photon imaging; non-human primates; humans; optics; neurons; dendrites
(This special issue belongs to the Section Neuroscience)
Young Researchers in Conservation Biology and Biodiversity
edited by
submission deadline 31 May 2025 | Viewed by 3 | Submission Open
Keywords: population genomics and diversity; heterozygosity; inbreeding; hybridization; adaptive introgression; natural selection; speciation; bottleneck and population fragmentation; genetic drift; gene flow; extinction risk; evolvability; paleogenomics; phylogeography; conservation units; ecotypes; phylogenetics and systematics; eDNA; non-invasive genetic sampling; environmental monitoring
(This special issue belongs to the Section Conservation Biology and Biodiversity)
Research Progress on Salt Stress in Plants
edited by
submission deadline 31 May 2025 | Viewed by 2 | Submission Open
Keywords: salt stress; plants; crops; soil salinization; salt tolerance; abiotic stress; plant protection; plant breeding
(This special issue belongs to the Section Plant Science)
The Biology and Behavior of Bees
edited by
submission deadline 31 May 2025 | Viewed by 1 | Submission Open
Keywords: pollinators; bee anatomy; bee foraging behavior; bee communication; bee social structure; environmental stressors of bees; effect of pesticide on bees’ behavior; bees’ habitat loss; natural enemies of bees; bees’ disease management
(This special issue belongs to the Section Zoology)
Biomarkers in Stress Biology and Ecology submission deadline 1 Jun 2025 | 2 articles | Viewed by 3825 | Submission Open
Keywords: biomarkers; ecotoxicology; environmental contamination; stress ecology; neurotoxicity; oxidative stress; pollution
Animal Models of Neurodegenerative Diseases
edited by Xiangyu Guo
submission deadline 1 Jun 2025 | 1 articles | Viewed by 1071 | Submission Open
Keywords: neurodegenerative diseases; Alzheimer's disease; amyotrophic lateral sclerosis; Parkinson's disease; Huntington's disease; neuroscience; animal models; pathogenesis
(This special issue belongs to the Section Neuroscience)
Wetland Ecosystems (2nd Edition)
edited by , Chenglang Pan and Qiang Wang
submission deadline 1 Jun 2025 | Viewed by 168 | Submission Open
Keywords: biological invasion; pollution; carbon sink function; the biogeochemical cycle of biogenic elements; population and community ecology; global climate change; coastal zone management; the structure and function of the microbiome; environmental adaptation mechanisms of wetland organisms; wetland landscape; wetland degradation
(This special issue belongs to the Section Ecology)
Recent Advances in Biosynthesis and Degradation of Plant Anthocyanin
edited by and
submission deadline 15 Jun 2025 | 4 articles | Viewed by 6667 | Submission Open
Keywords: anthocyanin; fruit ripening; flowering coloration; leaf coloration; secondary metabolite; molecular mechanism
(This special issue belongs to the Section Plant Science)
From Basics to Applications of Gene Regulatory Networks
edited by
submission deadline 15 Jun 2025 | 1 articles | Viewed by 1042 | Submission Open
Keywords: gene regulatory networks; computational methods; modeling and simulation; disease mechanisms; therapeutic targeting; transcriptomics
(This special issue belongs to the Section Genetics and Genomics)
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