New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (2nd Edition)
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Cell Biology and Pathology".
Deadline for manuscript submissions: 28 February 2025 | Viewed by 736
Special Issue Editors
2. Associate Laboratory i4HB—Institute for Health and Bioeconomy, Faculdade de Farmácia da Universidade do Porto, Porto, Portugal
3. TOXRUN—Toxicology Research Unit, University Institute of Health Sciences, Cooperativa de Ensino Superior Politécnico e Universitário (CESPU), CRL, 4585-116 Gandra, Portugal
Interests: biomarkers; chronic kidney disease; inflammation; cardiovascular disease risk factors
Special Issues, Collections and Topics in MDPI journals
2. Associate Laboratory i4HB—Institute for Health and Bioeconomy, Faculdade de Farmácia da Universidade do Porto, Porto, Portugal
Interests: chronic kidney disease; CKD anemia; cardiovascular disease risk; anemia; inflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Chronic kidney disease (CKD) is characterized by a progressive and usually irreversible deterioration of renal function. The worsening of CKD is associated with a high burden of comorbidities, and in patients on dialysis treatment for end-stage kidney disease (ESKD), the mortality rate is 10- to 20-fold higher than in the general population. ESKD patients commonly present with chronic inflammation, protein–energy malnutrition, and progressive cardiovascular disease (CVD), which is the most common cause of mortality. Inflammation can be a trigger and/or consequence of CKD; it may result from the primary cause of CKD, such as in diabetes and hypertension, and be favored by renal dysfunction changes (e.g., uremia, oxidative stress, metabolic acidosis).
Ensuring a better understanding of the uremic milieu of CKD pathophysiology and its relationship with its comorbidities is the main focus of this Special Issue. The identification of biomarkers, or panels of biomarkers, of cardiorenal syndrome and early kidney injury will help clinicians when making therapeutic decisions and choosing earlier and more adequate therapeutic strategies, thus avoiding or minimizing CKD progression. The investigation of novel therapeutic approaches should also be encouraged.
Dr. Susana Coimbra
Dr. Alice Santos-Silva
Guest Editors
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Keywords
- inflammation
- kidney biomarkers
- kidney injury
- chronic kidney disease
- dialysis
- cardiorenal syndrome risk
- CKD anemia
- kidney physiopathology
- CKD treatment
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