Animal and Cellular Models of Alzheimer’s Disease
A special issue of Biomedicines (ISSN 2227-9059). This special issue belongs to the section "Neurobiology and Clinical Neuroscience".
Deadline for manuscript submissions: closed (31 August 2023) | Viewed by 22877
Special Issue Editors
Interests: Alzheimer's disease; multiple sclerosis, human pluripotent stem cells; glial cells
Special Issues, Collections and Topics in MDPI journals
Interests: induced pluripotent stem cells; cellular disease models; CRISPR; neurodegeneration and models of neurodegeneration
Special Issues, Collections and Topics in MDPI journals
2. Centro de Investigación Biomedica en Red Sobre Enfermedades Neurodegenerativas (CIBERNED), Madrid, Spain
Interests: Alzheimer's disease; animal models; diabetes; obesity; insulin resistance; tau; cognitive impairments; inflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alzheimer’s disease (AD) is a neurodegenerative condition with no cure. In the last three decades, important efforts have been made in the development and characterization of animal models of the disease, with the aim to translate the discoveries made toward the clinical setting. Nonetheless, to date, there is no effective treatment able to counteract the progression of AD. This points toward an urgent need to develop new and more reliable models of the disease.
This Special Issue is focused on manuscripts describing and/or characterizing new animal and cellular models for AD. Special attention will be given to those works employing humanized animal models as well as studies based on human pluripotent stem cell technologies, strategies that should govern AD research in the coming years.
This Special Issue is open to basic and clinical research or multidisciplinary approaches and will also cover original articles and reviews on the following topics:
- Characterization of new models relevant for AD;
- Studies performed employing new cellular and animal models focused on AD;
- Studies employing human pluripotent stem-cell-derived neuronal and glial cells for AD or other neurodegenerative conditions;
- Evaluation of candidate therapies;
- Modeling of Alzheimer’s disease or other neurodegenerative conditions.
Dr. Juan A. García León
Dr. Kristine Freude
Dr. David Baglietto-Vargas
Guest Editors
Manuscript Submission Information
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Keywords
- Alzheimer’s disease
- cellular models
- animal models
- humanized models
- human pluripotent stem cells
- drug evaluation
- neurodegenerative diseases
- glial cells
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