Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diagnostic Biomarkers and Novel Therapeutics Targets for Fragile X Syndrome, Autism Spectrum Disorders and Genetic Neurodevelopmental Diseases: Advances and Challenges
edited by Yolanda De Diego-Otero and Rocio Calvo-Medina
submission deadline 31 Jan 2025 | 6 articles | Viewed by 7782 | Submission Open
(This special issue belongs to the Section Molecular and Translational Medicine)
Cerebral Hemorrhages: From Pathophysiologic Mechanisms to Therapeutic Strategies
edited by Yingfeng Wan
submission deadline 31 Jan 2025 | 6 articles | Viewed by 7085 | Submission Open
Keywords: hemorrhagic stroke; white matter injury; brain blood barrier; phagocytosis; hemolysis; immune cells; aging; sex difference; vasospasm; blood‒cerebrospinal fluid barrier
(This special issue belongs to the Section Molecular and Translational Medicine)
Personalized Treatment in Cancer Research submission deadline 31 Jan 2025 | 4 articles | Viewed by 6720 | Submission Open
Keywords: cancer; personalized medicine; personalized treatment; pharmacogenetics; pharmacokinetics; chemotherapy; adjuvant treatment; therapeutic drug monitoring
(This special issue belongs to the Section Cancer Biology and Oncology)
Crohn's Disease and Ulcerative Colitis: From Pathophysiology to Novel Therapeutic Approaches (2nd Edition)
edited by
submission deadline 31 Jan 2025 | 6 articles | Viewed by 6223 | Submission Open
Keywords: inflammatory bowel disease; crohn's disease; ulcerative colitis; chronic inflammation; pathophysiological mechanisms; therapeutic approaches; stem cell transplantation; fecal microbiota transplantation; gut microbiome; targeted therapies
(This special issue belongs to the Section Cell Biology and Pathology)
Exploring Acute Coronary Syndrome: Insights from Basic and Clinical Research
edited by
submission deadline 31 Jan 2025 | 5 articles | Viewed by 6207 | Submission Open
Keywords: acute coronary syndrome; cardiovascular morbidity; myocardial infarction; pathophysiology; diagnostic modalities; therapeutic interventions; translational research
(This special issue belongs to the Section Molecular and Translational Medicine)
New Molecular Insights into the Pathogenesis and Drug Development of Neurodegenerative Diseases
edited by Aifang Cheng and Beika Zhu
submission deadline 31 Jan 2025 | 5 articles | Viewed by 5920 | Submission Open
Keywords: neurodegenerative diseases; pathogenesis; molecular mechanisms; high-throughput drug screening; drug repurposing; cellular and animal models; brain organoids; mode of action; pharmacological evaluations; preclinical study
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
State-of-the-Art Surfactant in Biomedical Application: A Commemorative Issue in Honor of Prof. Tetsuro Fujiwara
edited by
submission deadline 31 Jan 2025 | 4 articles | Viewed by 5234 | Submission Open
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Molecular Mechanism in Inflammation and Immunity
edited by Anella Saviano
submission deadline 31 Jan 2025 | 2 articles | Viewed by 4959 | Submission Open
Keywords: adaptive immunity; autoimmune-based diseases; cyto/chemokines; inflammation; macrophages; natural compounds; nutraceuticals; signaling pathway in arachidonic acid cascade; T-cells; trained immunity
(This special issue belongs to the Section Cell Biology and Pathology)
Integrative Genomic Analysis, Big Data Processing and Programming, and Pharmaco-Informatics in Biomedicine
edited by
submission deadline 31 Jan 2025 | 3 articles | Viewed by 4916 | Submission Open
Keywords: computational genomics; big data processing and programming; cancer genetics; immunobiology; immune checkpoint response prediction; drug target identification and validation; network pharmacology; pharmacogenomics; system biology; protein– ligand interaction
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
The Role of Telomere and Telomerase in Human Disease
edited by
submission deadline 31 Jan 2025 | 3 articles | Viewed by 4850 | Submission Open
Keywords: telomere; telomerase; cancer; aging  
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Disease Biomarkers in the Precision Medicine Era: A Comprehensive Multi-Omics Analysis
edited by
submission deadline 31 Jan 2025 | 4 articles | Viewed by 4589 | Submission Open
Keywords: personalized medicine; disease biomarkers: screening and diagnosis; multi-omics analysis; epidemiology
(This special issue belongs to the Section Molecular and Translational Medicine)
Cellular and Molecular Mechanisms in Gastrointestinal Tract Disease
edited by Felipe Leite De Oliveira
submission deadline 31 Jan 2025 | 3 articles | Viewed by 3803 | Submission Open
Keywords: cellular mechanisms; molecular mechanisms; diagnosis; treatment; experimental models; signaling pathways; comorbidities
(This special issue belongs to the Section Cell Biology and Pathology)
Sepsis and Septic Shock: From Molecular Mechanism to Novel Therapies
edited by Fuhong Su
submission deadline 31 Jan 2025 | 4 articles | Viewed by 3617 | Submission Open
Keywords: sepsis; septic shock; molecular mechanisms; specific biomarkers; histone
(This special issue belongs to the Section Cell Biology and Pathology)
Neuroinflammation: From Pathophysiologic Mechanisms to Therapeutic Strategies
edited by Li-Ping Zhou
submission deadline 31 Jan 2025 | 2 articles | Viewed by 3339 | Submission Open
Keywords: neuroinflammation; molecular mechanism; anti-inflammation; stem cell-based therapy; cell-free stem-cell-based therapy; immunomodulation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Cardiac Arrhythmias and Arrhythmogenic Disorders: Technological Frontiers, Drug Development and Future Directions
edited by Siamak Salavatian
submission deadline 31 Jan 2025 | 2 articles | Viewed by 3278 | Submission Open
Keywords: cardiac arrhythmias; arrhythmias diagnostic; arrhythmias therapy; technological frontiers; personalized medicine; biomarkers; neuromodulation; artificial intelligence
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Mechanisms of Antibody-Mediated Rejection and Accommodation in Kidney Transplantation
edited by and Ayman Al Jurdi
submission deadline 31 Jan 2025 | 2 articles | Viewed by 3100 | Submission Open
Keywords: kidney transplant; transplant immunology; recurrent glomerular disease; clinical trials; rejection; crossmatching; allocation; CMV; BK nephropathy
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Pain Medicine
edited by
submission deadline 31 Jan 2025 | 3 articles | Viewed by 3025 | Submission Open
Keywords: pain medicine; neuromodulation; neurostimulators
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Epilepsy: From Mechanisms to Therapeutic Approaches
edited by
submission deadline 31 Jan 2025 | 3 articles | Viewed by 2707 | Submission Open
Keywords: genetic epilepsy; acquired epilepsy; neonatal seizures; epileptogenesis; pharmacoresistant epilepsy; ion channels; calcium signaling
(This special issue belongs to the Section Molecular and Translational Medicine)
Unraveling the Molecular Mechanisms of Heart and Skeletal Muscle Pathologies submission deadline 31 Jan 2025 | 2 articles | Viewed by 2567 | Submission Open
Keywords: cardiomyopathies; skeletal myopathies; molecular basis of cardiac and skeletal pathologies; pre-clinical models; including animal and cell-based models.
(This special issue belongs to the Section Cell Biology and Pathology)
mTOR Signaling in Disease and Therapy
edited by Wenjing Yu and
submission deadline 31 Jan 2025 | 2 articles | Viewed by 2086 | Submission Open
Keywords: mTOR signaling; tissue engineering; stem cell; disease; therapy; bone; craniofacial; biomedicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Novel Approaches towards Targeted Head and Neck Cancer Therapies
edited by
submission deadline 31 Jan 2025 | 2 articles | Viewed by 2082 | Submission Open
Keywords: EGFR; VEGFR; RET; MET; PI3K; radiotherapy; chemotherapy; immunotherapy; HPV; preclinical HNSCC model; biomarkers of treatment response
(This special issue belongs to the Section Cancer Biology and Oncology)
The Role of Extracellular Vesicles in Hepatic, Pancreatic and Biliary Diseases
edited by David R. Brigstock and Xinlei Li
submission deadline 31 Jan 2025 | 1 articles | Viewed by 2081 | Submission Open
Keywords: exosome; extracellular vesicle; microvesicle; steatosis; hepatitis; pancreatitis; hepatocarcinoma; pancreatic ductal adenocarcinoma; diabetes; fibrosis; bile duct; liver; pancreas
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Proteinopathies submission deadline 31 Jan 2025 | 1 articles | Viewed by 1807 | Submission Open
Keywords: protein misfolding; oligomers; amyloid fibrils; amorphous aggregates; prion; neurodegeneration; aggregation kinetics; neurotoxicity; drug discovery
(This special issue belongs to the Section Cell Biology and Pathology)
Pathogenic RNA Viruses: Mechanisms of Viral Replication, Viral–Host Interactions and Antiviral Development
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1774 | Submission Open
Keywords: RNA virus; protein– RNA interactions; RNA structure and function; virus– host cell interactions; virus assembly and replication; viral vectors; therapeutic development
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Targeting the Resistant Tumor Microenvironment in Lymphoma: From Basic Science to Artificial Intelligence
edited by Rada Amin
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1655 | Submission Open
Keywords: lymphoma; tumor microenvironment; tumor– immune cell interaction; immunotherapy; machine learning; bioimaging; artificial intelligence; immunology
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research in Diabetic Kidney Disease submission deadline 31 Jan 2025 | 1 articles | Viewed by 1599 | Submission Open
Keywords: diabetic kidney disease; chronic kidney disease; end-stage renal disease
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Protein Kinase C Signalling in Health and Disease: A Commemorative Issue in Honor of Prof. Yasutomi Nishizuka submission deadline 31 Jan 2025 | 1 articles | Viewed by 1465 | Submission Open
Keywords: novel signaling mechanisms; cell metabolism; omnics/signaling; immunity; cancer; neurobiology
(This special issue belongs to the Section Cell Biology and Pathology)
Angiogenesis and Related Disorders
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1323 | Submission Open
Keywords: angiogenesis; cardiovascular diseases; cancers; diabetic complications; therapeutic target; biomarkers; drug development; clinical implementation
(This special issue belongs to the Section Molecular and Translational Medicine)
Role of Bone Marrow Niche in Haematological Cancers submission deadline 31 Jan 2025 | 1 articles | Viewed by 1319 | Submission Open
Keywords: blood cancers; bone marrow; microenvironment; immune stromal interactions; mesenchymal stem cells
(This special issue belongs to the Section Cancer Biology and Oncology)
Nano-Medicine: Revolutionizing Therapeutics, Diagnostics, and Regeneration
edited by Sonali Suresh Rohiwal
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1299 | Submission Open
Keywords: drug delivery systems; targeted therapies; disease detection; tissue regeneration; regenerative medicine; nanomaterials
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Advances in Fabry Disease: From Molecular Insights to Innovative Therapeutics
edited by and Concetto Sessa
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1069 | Submission Open
Keywords: fabry disease; lysosomal storage disorder; GLA gene mutations; enzyme replacement therapy; chaperone therapy; physical activity; imagining
(This special issue belongs to the Section Molecular and Translational Medicine)
Breast Cancer: New Diagnostic and Therapeutic Approaches
edited by , and Sara Bravaccini
submission deadline 31 Jan 2025 | 2 articles | Viewed by 1059 | Submission Open
Keywords: breast cancer; breast oncology; circulating tumor cells
(This special issue belongs to the Section Cancer Biology and Oncology)
Genetic and Epigenetics of Kidney Development: Pathologies of Renal Anomalies and Kidney Diseases
edited by Hongbing Liu
submission deadline 31 Jan 2025 | 1 articles | Viewed by 1052 | Submission Open
Keywords: genetics; epigenetics; CAKUT; kidney development; kidney diseases
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Coronary Heart Disease: Causes, Pathology and Treatment submission deadline 31 Jan 2025 | 1 articles | Viewed by 938 | Submission Open
Keywords: CHD; dyslipidemia; hypertension; diabetes; myocardial infarction; cardiac rehabilitation; cardiovascular prevention
(This special issue belongs to the Section Molecular and Translational Medicine)
Mechanisms and Novel Therapeutic Approaches for Gliomas
edited by Maria V. Chatziathanasiadou
submission deadline 31 Jan 2025 | 1 articles | Viewed by 807 | Submission Open
Keywords: glioma; molecular mechanisms; signaling; tumour immunity; tumour metabolism; tumour microenvironment; metabolic therapies; immunotherapies; combination treatment
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Polycystic Ovary Syndrome Research: From Molecular Mechanisms to Therapeutic Strategies—2nd Edition
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 510 | Submission Open
Keywords: female infertility; endocrine disorder; metabolic disorder; polycystic ovary syndrome; polycystic ovariany morphology; hyperandrogenism; menstrual irregularity; theraputicsTherapeutics; oxidative stress; antioxidant
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Stem Cells and Immunomodulation
edited by
submission deadline 31 Jan 2025 | Viewed by 499 | Submission Open
Keywords: pre-conditioning and priming of stem cells; new immunomodulatory assays; immunomodulation in 3D cell culture; organoids and spheroids; novel immunomodulatory properties of stem cells; antimicrobial stem cells; wharton jelly and umbilical cord stem cells; novel immune targets of stem cell factors; immunotolerance by stem cells; immunophenotyping of new stem cell sources; immunomodulation by progenitor cells
(This special issue belongs to the Section Immunology and Immunotherapy)
Gut Microbiota, Diet, and Immunity: Investigating the Connections and Implications for Disease Development: 2nd Edition
edited by
submission deadline 31 Jan 2025 | 1 articles | Viewed by 452 | Submission Open
Keywords: gut microbiota; diet; immunity; microbiome; dysbiosis; inflammatory bowel diseases; cancer; CVD; T2D; obesity; overweight; autoimmune diseases; metabolic syndromes; immunomodulation; microbial diversity; nutrient– gut microbiota interactions; probiotics; prebiotics; immune system development; disease susceptibility; therapeutic interventions; host– microbe interactions; gut– brain axis; microbial metabolites; precision nutrition
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Advanced Research on Drugs Against Breast Cancer: From Bench to Bedside
edited by Lunawati Bennett
submission deadline 31 Jan 2025 | Viewed by 436 | Submission Open
Keywords: breast cancer; drug discovery; therapeutic targets; preclinical studies; clinical trials; molecular mechanism; biomarkers; drug resistance; combination therapies; translational research
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Cardiovascular Diseases submission deadline 31 Jan 2025 | Viewed by 427 | Submission Open
Keywords: cardiovascular diseases; heart failure; cardiac arrhythmias; metabolic syndrome; stroke; pulmonary hypertension; peripheral artery disease (PAD); acute coronary syndrome; myocarditis; pericarditis; valvulopathies
(This special issue belongs to the Section Molecular and Translational Medicine)
Immune Checkpoints and Autoimmunity — Volume II
edited by
submission deadline 31 Jan 2025 | Viewed by 370 | Submission Open
Keywords: immune checkpoint molecules; autoimmune diseases; inflammatory diseases; checkpoint inhibitor therapy; inflammation
(This special issue belongs to the Section Immunology and Immunotherapy)
Mitochondrial Dysfunction and Oxidative Stress
edited by
submission deadline 31 Jan 2025 | Viewed by 364 | Submission Open
Keywords: mitochondria; oxidative stress; brain metabolism; neurodevelopmental diseases; neuropsychiatric diseases; neurodegenerative diseases; mitochondrial medicine; translational medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Research in Obesity, 2nd Edition
edited by Zaida Abad-Jiménez and
submission deadline 31 Jan 2025 | Viewed by 348 | Submission Open
Keywords: obesity; genetics; molecular pathways; adipose tissue; metabolism; leukocytes; prevention; new targets for treatment; translational studies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Role of Oxidized Lipids in Cardiovascular Diseases
edited by
submission deadline 31 Jan 2025 | Viewed by 345 | Submission Open
Keywords: oxidized lipids; antioxidants; fatty acids; lipoproteins; atherosclerosis; cardiovascular disease; inflammation; oxysterol; macrophages; endothelial dysfunction; smooth muscle cell; proliferation
(This special issue belongs to the Section Molecular and Translational Medicine)
Biotechnology in the Treatment and Management of Hearing Loss submission deadline 31 Jan 2025 | Viewed by 332 | Submission Open
Keywords: hearing loss; gene therapy; regenerative medicine; cochlear implants; nanotechnology stem cell therapy; CRISPR-Cas9; auditory prosthetics; artificial intelligence; auditory regeneration
(This special issue belongs to the Section Biomedical Engineering and Materials)
Natural Product for the Interventions of Chronic Diseases: From Source to Therapy
edited by
submission deadline 31 Jan 2025 | Viewed by 272 | Submission Open
Keywords: natural products; chronic diseases; drug discovery; pharmacodynamics; pharmacokinetics; nanotechnology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Role of Gut Microbiota in Disease Prevention
edited by Luka Bočkor and
submission deadline 31 Jan 2025 | Viewed by 259 | Submission Open
Keywords: gut microbiota; disease prevention; metabolism; gut– brain axis; prebiotics; probiotics
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Inflammatory Chaos in Helicobacter pylori Infection submission deadline 31 Jan 2025 | Viewed by 222 | Submission Open
Keywords: Helicobacter pylori; cytokine; chemokine; TLRs; inflammasome; T4SS; gastric inflammation; gastric ulcer; gastric cancer
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Long Noncoding RNAs in Brain Diseases
edited by
submission deadline 31 Jan 2025 | Viewed by 181 | Submission Open
Keywords: long non-coding RNAs; brain diseases; neurodegenerative diseases; Alzheimer's disease; Parkinson's disease; Huntington's disease; amyotrophic lateral sclerosis; psychiatric disorders; brain tumors; neurodevelopmental disorders
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Diagnostics and Monitoring in Tuberculosis
edited by Yi-Wei Tang and
submission deadline 31 Jan 2025 | Viewed by 173 | Submission Open
Keywords: tuberculosis; line probe assays; mycobacterial culture; phenotypic susceptibility testing; real-time PCR; whole-genome sequencing; omics techniques
(This special issue belongs to the Section Molecular and Translational Medicine)
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