Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Current Trends in Diabetic Foot Disease
edited by Xuefeng Yu
submission deadline 27 Feb 2026 | Viewed by 196 | Submission Open
Keywords: diabetes; diabetic foot; endocrinology; metabolic disease
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Pathology, Complications and Prognosis of Type 1 Diabetes
edited by Maurizio Delvecchio
submission deadline 27 Feb 2026 | Viewed by 57 | Submission Open
Keywords: type 1 diabetes mellitus; autoimmune β -cell destruction; diabetic complications; microvascular and macrovascular damage; diabetic ketoacidosis; glycemic control; disease prognosis; immunopathogenesis
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advanced Research of Gut Microbiota in Health and Diseases—2nd Edition submission deadline 28 Feb 2026 | 8 articles | Viewed by 19316 | Submission Open
Keywords: microbiota; gut; dysbiosis; gut microbiome; pathological conditions; metabolic disorders; autoimmune disease; inflammatory disorders; degenerative diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Cellular and Molecular Biology of Neurodegenerative Disorders
edited by
submission deadline 28 Feb 2026 | 5 articles | Viewed by 14738 | Submission Open
Keywords: neurodegeneration; omics; biomarkers; systems biology; disease-modifying therapies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Glioblastoma: Pathogenetic, Diagnostic and Therapeutic Perspectives submission deadline 28 Feb 2026 | 5 articles | Viewed by 14390 | Submission Open
Keywords: drug delivery methods (TTFields; nanoparticles); immunotherapy; oncolytic virotherapy; cell metabolism (glycolysis; OXPHOS; fatty acid oxidation); epigenetic; biomarkers; gene therapy (CRISPR/Cas9)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Cellular and Pathogenesis Mechanisms in Oral Cancer
edited by
submission deadline 28 Feb 2026 | 5 articles | Viewed by 13442 | Submission Open
Keywords: oral carcinogenesis; oral cancer model; OSCC; oral cytology; biomarkers; targeted therapies; precision medicine; bioinformatics
(This special issue belongs to the Section Molecular and Translational Medicine)
Musculoskeletal Injuries: Clinical, Radiological, and Biochemical Evaluation in Orthopedics submission deadline 28 Feb 2026 | 6 articles | Viewed by 12225 | Submission Open
Keywords: orthopedic surgery; sports injuries; bone cancer; diabetic foot; clinical evaluation; radiological evaluation; biomarkers; prognostic markers
(This special issue belongs to the Section Molecular and Translational Medicine)
Natural Product for the Interventions of Chronic Diseases: From Source to Therapy
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 12065 | Submission Open
Keywords: natural products; chronic diseases; drug discovery; pharmacodynamics; pharmacokinetics; nanotechnology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Feature Reviews in Cell Death
edited by and Madalina Nistor
submission deadline 28 Feb 2026 | 4 articles | Viewed by 10100 | Submission Open
Keywords: cell death pathways; apoptosis; necrosis; biomarkers; therapies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Progress in Cardiovascular Pharmacology submission deadline 28 Feb 2026 | 3 articles | Viewed by 8653 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pharmacology; target therapies; molecular pharmacology; heart failure; preventive cardiology; atherosclerosis
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Neuroendocrine Neoplasia and Endocrine Tumors: Pathogenic Features, Prognostic Markers and New Therapeutic Approaches
edited by
submission deadline 28 Feb 2026 | 5 articles | Viewed by 7891 | Submission Open
Keywords: neuroendocrine tumors; endocrine tumors; somatostatin analogues; carcinoid syndrome; PRRT; mTOR inhibitor; lymph node; neuroendocrine marker; hormone; ki67
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Feature Reviews in Mesenchymal Stem Cells submission deadline 28 Feb 2026 | 2 articles | Viewed by 7736 | Submission Open
Keywords: mesenchymal stem cells; tissue repair and regeneration; immunomodulatory functions
(This special issue belongs to the Section Cell Biology and Pathology)
Advances in Biomarker Discovery for Cardiovascular Disease
edited by and
submission deadline 28 Feb 2026 | 6 articles | Viewed by 7030 | Submission Open
Keywords: cardiovascular disease; genomics; transcriptomics; proteomics; metabolomics; multiomics; gene sequencing; liquid chromatography/gas chromatography tandem mass spectrometry; diagnostic biomarkers; biomedicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Liquid Biopsy from Technological Innovation to Therapeutic Intervention
edited by and
submission deadline 28 Feb 2026 | 4 articles | Viewed by 6472 | Submission Open
Keywords: liquid biopsy; biomarkers; circulating tumor cells
(This special issue belongs to the Section Molecular and Translational Medicine)
Progress in Nanotechnology-Based Therapeutic Strategies
edited by Ambra Del Grosso and Mariacristina Gagliardi
submission deadline 28 Feb 2026 | 3 articles | Viewed by 5202 | Submission Open
Keywords: nanotechnology-based therapies; targeted drug delivery; nanoparticles; nanostructures; cancer treatment; cardiovascular diseases; neurodegenerative diseases; infectious diseases; lysosomal storage disorders; regenerative medicine; tissue engineering; gene therapy; biochemical diagnostics; omics approaches; biological barriers
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Animal Models for the Study of Human Diseases
edited by
submission deadline 28 Feb 2026 | 4 articles | Viewed by 4895 | Submission Open
Keywords: animal models; zebrafish; mice; rats
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research in Breast Diseases and Histopathology
edited by Michał Budzik
submission deadline 28 Feb 2026 | 3 articles | Viewed by 4819 | Submission Open
Keywords: breast cancer; breast diseases; histopathology; biomarkers; screening; diagnosis; early detection; tumor microenvironment; pathophysiology; molecular biology
(This special issue belongs to the Section Cell Biology and Pathology)
Diabetes: Comorbidities, Therapeutics and Insights (3rd Edition)
edited by
submission deadline 28 Feb 2026 | 3 articles | Viewed by 3712 | Submission Open
Keywords: diabetes; complications; diabetic retinopathy; diabetic neuropathy; diabetic nephropathy; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of Ion Channels and Transporters in Human Health and Diseases (2nd Edition)
edited by Teresa Soda
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3620 | Submission Open
Keywords: ion channels; transporters; ion pumps; voltage-gated channels; ionotropic receptors; TRP channels; store-operated channels; piezo channels; NALCN channels; inositol-1; 4; 5-receptors; ryanodine receptors; two-pore channels; synaptic transmission; channelopathies; neurodegenerative disorders; cardiovascular disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Urticaria: New Insights into Pathogenesis, Diagnosis and Therapy
edited by
submission deadline 28 Feb 2026 | 2 articles | Viewed by 3468 | Submission Open
Keywords: acute urticaria; chronic urticaria; pathogenesis; mast cells; biomarkers; diagnosis; biologicals
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular Research in Ocular Pathology submission deadline 28 Feb 2026 | 2 articles | Viewed by 3274 | Submission Open
Keywords: molecular pathology; ocular diseases; biomarkers; diabetic retinopathy; glaucoma; age-related macular degeneration; thyroid eye disease; inflammatory pathways; oxidative stress; angiogenesis; neurodegeneration; gene therapy; cell therapy; precision medicine; ocular imaging
(This special issue belongs to the Section Molecular and Translational Medicine)
Endothelial Dysfunction: From a Pathophysiological Mechanism to a Potential Therapeutic Target—3rd Edition submission deadline 28 Feb 2026 | 1 articles | Viewed by 3272 | Submission Open
Keywords: endothelial function; arterial stiffness; vascular medicine; cardiovascular risk; nitric oxide; reactive oxygen species; interleukins; inflammation; biomarkers
(This special issue belongs to the Section Cell Biology and Pathology)
Kidney Diseases in Critical Ill Patients
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 3196 | Submission Open
Keywords: acute kidney disease; critical care; beside diagnostics; point of care ultrasounds; dialysis
(This special issue belongs to the Section Molecular and Translational Medicine)
Advanced Research on Skeletal Muscle Metabolism
edited by Lorenzo Sanesi
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2941 | Submission Open
Keywords: energy metabolism; mebabolic signaling pathways; homeostasis; myokines; aging; atrophy; muscle metabolism
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Cardiovascular Remodeling: Molecular Mechanisms and Therapeutic Targets
edited by
submission deadline 28 Feb 2026 | 3 articles | Viewed by 2908 | Submission Open
Keywords: cardiac remodeling; vascular remodeling; ageing; pathogenesis; molecular mechanisms; diagnostics; therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Biotechnology in the Treatment and Management of Hearing Loss submission deadline 28 Feb 2026 | 2 articles | Viewed by 2834 | Submission Open
Keywords: hearing loss; gene therapy; regenerative medicine; cochlear implants; nanotechnology stem cell therapy; CRISPR-Cas9; auditory prosthetics; artificial intelligence; auditory regeneration
(This special issue belongs to the Section Biomedical Engineering and Materials)
Mechanisms and Therapeutic Approaches for Hepatocellular Carcinoma
edited by Lanqi Gong, and Yu Zhang
submission deadline 28 Feb 2026 | 2 articles | Viewed by 2506 | Submission Open
Keywords: hepatocellular carcinoma; HCC diagnosis and prognosis; HCC mechanisms; therapeutic resistance; immunotherapy; targeted therapy; personalized medicine; drug development; clinical trials; translational studies
(This special issue belongs to the Section Cancer Biology and Oncology)
Autophagy, Apoptosis and Cancer: 2025 Update
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 2282 | Submission Open
Keywords: autophagy; apoptosis; glioblastoma; hypoxia-inducible factors (HIFs); female fertility and ovarian cancer; nanoparticle-based drug delivery; bioactive natural products
(This special issue belongs to the Section Cancer Biology and Oncology)
Recent Advances in Oral Medicine—2nd Edition submission deadline 28 Feb 2026 | 2 articles | Viewed by 2012 | Submission Open
Keywords: oral medicine; oral manifestations of systemic conditions; drug-induced lesions; oral pathologies; head and neck cancer; autoimmune; oral lesions; bisphosphonates; systemic pharmacotherapy; infectious diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Application of Artificial Intelligence in Biomedicines
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1854 | Submission Open
Keywords: artificial intelligence; generative artificial intelligence; precision medicine; clinical decision support; drug discovery; personalized therapy; trustworthy AI
(This special issue belongs to the Section Molecular and Translational Medicine)
Growth Hormone Disorders and Their Related Diseases: From Pathophysiology to Therapeutic Approaches
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1835 | Submission Open
Keywords: growth; growth hormone deficiency; GH; IGF-1; pediatric endocrinology
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Pluripotent Stem Cells: Current Understanding and Future Directions—2nd Edition submission deadline 28 Feb 2026 | 1 articles | Viewed by 1832 | Submission Open
Keywords: induced pluripotent stem cells; iPSC generation; somatic reprogramming; iPSC-derived cells; cell therapy; exosome therapy; therapeutic application; drug screening
(This special issue belongs to the Section Cell Biology and Pathology)
Neurodegenerative Diseases: From Mechanisms to Therapeutic Approaches, 2nd Edition submission deadline 28 Feb 2026 | 2 articles | Viewed by 1768 | Submission Open
Keywords: neurodegenerative diseases; neurons; mechanism
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Microcirculation, Thrombosis, and Inflammation in Peripheral Artery Disease and in the Brain submission deadline 28 Feb 2026 | 2 articles | Viewed by 1766 | Submission Open
Keywords: microcirculation; thrombosis; inflammation; peripheral artery disease; brain
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis and Treatment of Mycobacterium Tuberculosis Infection
edited by Sajid Nadeem
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1763 | Submission Open
Keywords: mycobacterium tuberculosis; pathogenesis; host-directed therapy; inflammation; necrosis; innate and adaptive immunity
(This special issue belongs to the Section Microbiology in Human Health and Disease)
New Insights into the Diagnosis and Treatment of Hepatocellular Carcinoma—2nd Edition
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1743 | Submission Open
Keywords: checkpoint inhibitors; combinatorial treatments; hepatocellular carcinoma (HCC); immunotherapy; liver cancer; therapy; targeted therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Congenital Heart Disease: Diagnosis, Treatment and Prognosis
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1444 | Submission Open
Keywords: adult congenital heart disease; eisenmenger's syndrome; endocarditis; thromboprophylaxis
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Precision Cancer Therapy
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1224 | Submission Open
Keywords: personalized cancer therapy; targeted therapy; immunotherapy; cancer genomics; cancer biomarker; liquid biopsy; CAR-T cell therapy; kinase inhibitor; combination therapy; molecular profiling
(This special issue belongs to the Section Cancer Biology and Oncology)
Progress in Cytotoxicity of Biomaterials
edited by Lakkamraju Vijayalakshmi
submission deadline 28 Feb 2026 | 1 articles | Viewed by 1067 | Submission Open
Keywords: biomaterial cytotoxicity; biocompatibility assessment; in vitro and in vivo toxicity; surface modification; nanomaterials in medicine; oxidative stress and inflammation; tissue engineering materials; drug delivery systems; biodegradable polymers; regulatory perspectives on biomaterial safety
(This special issue belongs to the Section Biomedical Engineering and Materials)
Innovations in Nanomedicine for Disease Management
edited by Anna Valentino and
submission deadline 28 Feb 2026 | 1 articles | Viewed by 684 | Submission Open
Keywords: nanomedicine; nanoparticles; smart drug delivery; personalized medicine; minimally invasive treatments; gene therapy; regenerative medicine
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Multisystem Crosstalk in Health and Disease submission deadline 28 Feb 2026 | 1 articles | Viewed by 591 | Submission Open
Keywords: systems biology; immunometabolism; inflammation; integrative physiology; molecular pathways; translational research; multi-omics; chronic disease; host– microbe interactions; metabolic regulation
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Gastric Cancer: Molecular and Translational Aspects on Carcinogenesis and Treatment
edited by Sharona B. Ross
submission deadline 28 Feb 2026 | 1 articles | Viewed by 590 | Submission Open
Keywords: gastric cancer; tumor microenvironment; molecular mechanism; targeted therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Peptide Therapeutic Approaches for Cancer Treatment submission deadline 28 Feb 2026 | Viewed by 505 | Submission Open
Keywords: peptide therapeutics; cancer treatment; drug delivery systems; molecular imaging; bioinformatics; machine learning and artificial intelligence (AI); therapeutic targeting; peptide– drug conjugates; personalized medicine; immunotherapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Pathophysiology and Therapeutic Innovations in Skin and Appendage Disorders
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 483 | Submission Open
Keywords: skin disorders; skin development; skin pathophysiology; tumorigenesis; psoriasis; atopic dermatitis; acne; innovative therapies; molecular dermatology; translational skin research
(This special issue belongs to the Section Cell Biology and Pathology)
Recent Advances in Adipokines (3nd Edition)
edited by
submission deadline 28 Feb 2026 | Viewed by 473 | Submission Open
Keywords: adiponectin; receptor; agonist; biomarker; inflammation; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
Thyroid Cancer: Molecular and Translational Aspects on Carcinogenesis and Treatment
edited by Sonam Kumari
submission deadline 28 Feb 2026 | 1 articles | Viewed by 378 | Submission Open
Keywords: radioactive iodine (RAI) treatment; tyrosine kinase inhibitors (TKIs); biomarkers; radiolabeled peptides; diagnostic markers; molecular targets; metastatic progressive thyroid cancer; overcoming resistance; personalized therapies; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Nervous System Injury and Repair: From Molecular Mechanism to Therapeutic Perspectives
edited by
submission deadline 28 Feb 2026 | 1 articles | Viewed by 373 | Submission Open
Keywords: nervous system injury; neuron; astrocytes; microglial cells; excitotoxicity; inflammation; oxidative stress; neuroprotection
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Demyelinating Diseases: Pathophysiology and Emerging Therapeutic Targets
edited by Jude Taylor
submission deadline 28 Feb 2026 | Viewed by 371 | Submission Open
Keywords: demyelinating diseases; pathophysiological processes; diagnostic accuracy and predicting disease; emerging strategies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Recent Advances in Primary and Relapsed Ovarian Cancer
edited by Cornelia Bachmann
submission deadline 28 Feb 2026 | Viewed by 364 | Submission Open
Keywords: ovarian cancer; relapse; BRCA; genetics; immunotherapy; biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
The Role of Environmental Pollutants in Cancer and Chemoresistance submission deadline 28 Feb 2026 | Viewed by 351 | Submission Open
Keywords: environmental pollutants; cancer cells; therapeutic agents
(This special issue belongs to the Section Cancer Biology and Oncology)
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