Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Channelopathies: Drug Interactions and Clinical Advances
edited by Cesar Celis Ceballos
submission deadline 28 Feb 2026 | Viewed by 79 | Submission Open
Keywords: electrophysiology; ion channels; channelopathies; drugs; patch-clamp
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Molecular Mechanisms of Cardiovascular Diseases (CVDs)
edited by
submission deadline 28 Feb 2026 | Viewed by 66 | Submission Open
Keywords: cardiovascular diseases (CVDs); molecular mechanisms; metabolic dysregulation; immunity; immunometabolism
(This special issue belongs to the Section Molecular and Translational Medicine)
Precision Approaches in the Diagnosis and Management of Inflammatory Bowel Disease
edited by
submission deadline 28 Feb 2026 | Viewed by 65 | Submission Open
Keywords: inflammatory bowel disease; ulcerative colitis; Crohn’ s disease; precision medicine; microbiome-based therapy; noninvasive diagnostics; stratified therapeutic response; immunometabolism; system immunology; therapeutic repurposing
(This special issue belongs to the Section Cell Biology and Pathology)
Metabolic Dysregulation in Chronic Kidney Disease: Emerging Mechanisms and Targeted Therapies
edited by
submission deadline 28 Feb 2026 | Viewed by 65 | Submission Open
Keywords: chronic kidney disease; metabolic dysregulation; biomarkers; gut-kidney axis; targeted therapy
(This special issue belongs to the Section Endocrinology and Metabolism Research)
New Insights in Immunological Pathways
edited by
submission deadline 28 Feb 2026 | Viewed by 64 | Submission Open
Keywords: immune response; immune signal pathway; cytokine storm
(This special issue belongs to the Section Immunology and Immunotherapy)
Advanced Research in Cancer Immunotherapy
edited by
submission deadline 28 Feb 2026 | Viewed by 63 | Submission Open
Keywords: immune checkpoint blockers; CAR-T; solid tumor; liquid tumor; cancer therapy; immunology
(This special issue belongs to the Section Cancer Biology and Oncology)
Liquid Biopsy in Tumor
edited by Heidi Fettke
submission deadline 28 Feb 2026 | Viewed by 62 | Submission Open
Keywords: cfDNA; ctDNA; liquid biopsy; solid tumors; fragmentomics; MRD; cancer genomics; non-invasive biomarkers; treatment resistance; precision oncology
(This special issue belongs to the Section Cancer Biology and Oncology)
3D Cell Culture Systems for Biomedical Research, 2nd Edition submission deadline 28 Feb 2026 | Viewed by 55 | Submission Open
Keywords: 3D; scaffolds; spheroids; biomaterials; tumour model; bioengineering; tissue regeneration; regenerative medicine; targeted therapies; tissue mimics; angiogenesis; cancerogenesis; drug development; 3D printing; material functionalisation
(This special issue belongs to the Section Biomedical Engineering and Materials)
Novel Biomarkers and Precision Medicine in Gynecologic Malignancies
edited by Zheng Feng
submission deadline 28 Feb 2026 | Viewed by 53 | Submission Open
Keywords: clinical trials; genomic landscape; targeted therapy; liquid biopsy; tumor screening; biomarker research; artificial intelligence
(This special issue belongs to the Section Cancer Biology and Oncology)
Molecular Mechanisms of Coronary Disease
edited by Quanyi Zhao and João P. Monteiro
submission deadline 28 Feb 2026 | Viewed by 53 | Submission Open
Keywords: atherosclerosis; coronary artery disease; cell fate transition; transcription; epigenetics; genetics; cytokine
(This special issue belongs to the Section Molecular and Translational Medicine)
Regenerative Medicine for Bone and Cartilage
edited by Deryk Jones
submission deadline 28 Feb 2026 | Viewed by 44 | Submission Open
Keywords: articular cartilage; bone marrow lesion; osteochondral allograft and autograft; chondrocyte; trabeculae; magnetic resonance image; regeneration
(This special issue belongs to the Section Biomedical Engineering and Materials)
Laser Applications in Medicine: Current Status and Emerging Challenges
edited by Irit Juwiler
submission deadline 16 Mar 2026 | Viewed by 336 | Submission Open
Keywords: lasers; medicine; surgery; dermatology; ophthalmology; dentistry; otolaryngology; gastroenterology; urology; gynecology; cardiology; neurosurgery; orthopedics; tissue types; biological interactions; technological advancements; clinical applications; health outcomes
(This special issue belongs to the Section Biomedical Engineering and Materials)
Recent Advances in Chronic Rhinosinusitis and Asthma: 2nd Edition
edited by and Cristiano Caruso
submission deadline 30 Mar 2026 | 1 articles | Viewed by 1368 | Submission Open
Keywords: asthma; chronic rhinosinusitis; nasal polyps; severe asthma; type-2 inflammation; phenotypes; endotypes; biologics; epithelial disfunction; remodeling
(This special issue belongs to the Section Molecular and Translational Medicine)
Biomarkers in Pain: 2nd Edition submission deadline 30 Mar 2026 | 1 articles | Viewed by 881 | Submission Open
Keywords: analgesia; biomarker; CSF; cytokine; inflammation; neuropathy; neurotransmitter; pain; QoL; sensitization; sensory
(This special issue belongs to the Section Molecular and Translational Medicine)
Metabolic Dysfunction-Associated Steatotic Disease
edited by Junzhao Ye
submission deadline 30 Mar 2026 | 1 articles | Viewed by 757 | Submission Open
Keywords: metabolic dysfunction-associated fatty liver disease; metabolic dysfunction-associated steatotic disease; novel classification using proteomic and metabolomic profiles; new kinds of lifestyle modification interventions; especially for nutrition interventions; radiologic advances in steatosis; inflammation; and fibrosis assessments; artificial intelligence applications; therapeutic innovations; microbiota
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Exploring Acute Coronary Syndrome: Insights from Basic and Clinical Research—2nd Edition
edited by
submission deadline 30 Mar 2026 | 1 articles | Viewed by 390 | Submission Open
Keywords: acute coronary syndrome; cardiovascular morbidity; myocardial infarction; pathophysiology; diagnostic modalities; therapeutic interventions; translational research
(This special issue belongs to the Section Molecular and Translational Medicine)
Genetic and Epigenetic Research on Kidney Diseases
edited by Hailong Hu
submission deadline 30 Mar 2026 | Viewed by 79 | Submission Open
Keywords: kidney disease; genetics; epigenetics; DNA methylation; non-coding RNAs; precision medicine; therapeutic target; nephrology
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Advanced Research in Cell and Tissue Engineering
edited by
submission deadline 30 Mar 2026 | Viewed by 69 | Submission Open
Keywords: cell and tissue engineering; regenerative medicine; stem cells; organoid; biomaterials; extracellular matrix (ECM); micro electro mechanical systems (MEMSs); microphysiological systems (MPSs); medical device; decellularization (decellularized tissue)
(This special issue belongs to the Section Biomedical Engineering and Materials)
Crohn’s Disease and Ulcerative Colitis: From Pathophysiology to Novel Therapeutic Approaches (3rd Edition)
edited by and Junsik Sung
submission deadline 31 Mar 2026 | 16 articles | Viewed by 22543 | Submission Open
Keywords: inflammatory bowel disease; Crohn’ s  disease; ulcerative colitis; chronic inflammation; pathophysiological mechanisms; therapeutic approaches; stem cell transplantation; fecal microbiota transplantation; gut microbiome; targeted therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Cholinergic System Neurodegeneration: Novel Pharmacotherapy
edited by and Paula Moyano
submission deadline 31 Mar 2026 | 1 articles | Viewed by 16553 | Submission Open
Keywords: cholinergic system; neurodegeneration; acetylcholine; cholinergic neurons; cholinergic pathologies; therapeutic approaches
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Long COVID: Mechanisms, Biomarkers, and Treatment submission deadline 31 Mar 2026 | 3 articles | Viewed by 14231 | Submission Open
Keywords: long-COVID; clinical observations; disease mechanism; biomarkers; treatment strategies; opinions
(This special issue belongs to the Section Cell Biology and Pathology)
Clinical Electrophysiology for Precision Diagnosis for Cardiology and Central Nervous System Diseases submission deadline 31 Mar 2026 | 3 articles | Viewed by 13131 | Submission Open
Keywords: brain; cardiology; precision medicine.
(This special issue belongs to the Section Molecular and Translational Medicine)
Saving Lives from Myocardial Infarction: Prevention vs. Therapy
edited by Dong Wang
submission deadline 31 Mar 2026 | 4 articles | Viewed by 11282 | Submission Open
Keywords: myocardial infarction; molecular markers; AI-powered early detection; wearable devices; ischemia– reperfusion injury; artificial intelligence; ventricular remodeling; fibrosis control; molecular imaging; genomics; transcriptomics; proteomics; metabolomics; MI prevention
(This special issue belongs to the Section Molecular and Translational Medicine)
Renal Cell Carcinoma: From Pathophysiology to Novel Therapeutic Approaches (3rd Edition) submission deadline 31 Mar 2026 | 4 articles | Viewed by 9904 | Submission Open
Keywords: renal cell carcinoma; pathology; physiology; diagnosis; multimodal treatment; drug resistance; biomarkers
(This special issue belongs to the Section Immunology and Immunotherapy)
Multidisciplinary Management of Rare Head and Neck Tumors: The Importance of Knowing and Dealing with Them
edited by
submission deadline 31 Mar 2026 | 3 articles | Viewed by 8878 | Submission Open
Keywords: rare head and neck cancers; translational research; therapeutic targets
(This special issue belongs to the Section Cancer Biology and Oncology)
Hepato-Pancreato-Biliary Cancers: Pathogenesis, Comorbidities and Therapy Updated submission deadline 31 Mar 2026 | 4 articles | Viewed by 8750 | Submission Open
Keywords: liver; bile; cancer; microbiome; pathogenesis; MiRNA; jaundice; disease; therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Lung Cancer: From Bench to Bedside
edited by
submission deadline 31 Mar 2026 | 6 articles | Viewed by 8613 | Submission Open
Keywords: lung cancer; immunotherapy; targeted therapy; translational oncology; biomarkers; EGFR; ALK; ROS1
(This special issue belongs to the Section Cancer Biology and Oncology)
Medicinal Cannabis: Advances in Therapeutics and Clinical Applications
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 6931 | Submission Open
Keywords: medicinal cannabis; cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN)
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
New Insights in Gastric, Colorectal, and Pancreatic Cancer submission deadline 31 Mar 2026 | 3 articles | Viewed by 6792 | Submission Open
Keywords: gastric cancer  ; colorectal cancer  ; pancreatic cancer; immunotherapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Connective Tissue Disorders: Pathogenetic, Diagnostic and Therapeutic Perspectives submission deadline 31 Mar 2026 | 3 articles | Viewed by 6335 | Submission Open
Keywords: connective tissue disorders; pathophysiological mechanisms; inflammation; autoimmunity; extracellular matrix; fibrosis; biomarkers; treatment; therapeutic targets
(This special issue belongs to the Section Molecular and Translational Medicine)
Gynecological Diseases in Cellular and Molecular Perspectives submission deadline 31 Mar 2026 | 3 articles | Viewed by 5096 | Submission Open
Keywords: gynaecological diseases; endometriosis; biomarkers; immune checkpoints; immunotherapy; tumor microenvironment; tumor-infiltrating immune cells; cancer immunology; cellular interactions
(This special issue belongs to the Section Molecular and Translational Medicine)
Drug Resistance and Tumor Microenvironment in Human Cancers
edited by , and Marília Isabel Neto Figueira
submission deadline 31 Mar 2026 | 2 articles | Viewed by 4984 | Submission Open
Keywords: cancer therapy; drug resistance; tumor microenvironment; targeted therapy; precision medicine; cancer-related mechanisms
(This special issue belongs to the Section Cancer Biology and Oncology)
Skin Diseases and Cell Therapy
edited by Nives Pondeljak, Maryam Heidari Kharaji and Mirna Šitum
submission deadline 31 Mar 2026 | 2 articles | Viewed by 4034 | Submission Open
Keywords: dermatology; psoriasis; atopic dermatitis; vitiligo; alopecia; cutaneous leishmaniasis; and skin fibrosis; skin cancers; innovative therapeutic strategies; molecular mechanisms
(This special issue belongs to the Section Gene and Cell Therapy)
Next-Generation Nanoparticles: Innovations in Biomedical Applications and Theranostics
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 3919 | Submission Open
Keywords: nanoparticles; nanoconjugates; antimicrobial agents; anticancer agents; biomedical applications
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Advanced Research in Thyroid and Parathyroid Diseases
edited by Anping Su
submission deadline 31 Mar 2026 | 3 articles | Viewed by 3236 | Submission Open
Keywords: thyroid cancer treatment; tumor microenvironment; immunotherapy; targeted therapy; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
New Horizons in Enzyme Inhibitor Discovery: Targets, Design and Evaluation
edited by Chenzhou Hao, Jing Guo, Yin Sun and Tongchao Liu
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2606 | Submission Open
Keywords: enzyme inhibitors; drug design; inhibitor screening; medicinal chemistry; targets validation; structure– activity relationship; structure– property relationship
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Impacts of Exercise, Nutrition, Obesity, Metabolism and Ageing on Regenerative Medicine and Their Applications in Tissue Engineering and Therapeutics
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2544 | Submission Open
Keywords: obesity; exercise; nutrition (diet); obesity; metabolism; ageing; regenerative medicine; tissue engineering; therapeutics
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Pathogenesis and Treatment of Ophthalmic Diseases
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2454 | Submission Open
Keywords: ophthalmology; AI; ocular; eye diseases; retina; cornea; glaucoma; neuro-ophthalmology
(This special issue belongs to the Section Molecular and Translational Medicine)
New Insights in Hypoxic Response Modulation
edited by Rafał Bartoszewski
submission deadline 31 Mar 2026 | 1 articles | Viewed by 2368 | Submission Open
Keywords: hypoxia; oxygen homeostasis; oxidative damage; cell death; ischemic events; stroke; myocardial infarction; tumor microenvironment (TME); noncoding RNA; MicroRNAs; long noncoding RNAs; PiRNA; hypoxia-inducible factors (HIFs); targeted delivery; hypoxic cells; regulatory networks; therapeutic opportunities
(This special issue belongs to the Section Cell Biology and Pathology)
Emerging Insights in Thoracic Diseases: From Diagnostics to Biomarkers and Therapeutic Implications Through Interdisciplinarity submission deadline 31 Mar 2026 | 3 articles | Viewed by 2333 | Submission Open
Keywords: chronic obstructive pulmonary disease; acute respiratory diseases; cardionephrology; interstitial lung disease; interventional cardiology; pulmonary fibrosis; tuberculosis; research methodology; biomarkers; therapeutics; artificial intelligence
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Immune Cell Biology: Insights from Molecular Perspectives
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2318 | Submission Open
Keywords: immune cell biology; cell signaling cascades; autoimmune disorders; immunoinflammatory pathways; hematological disorders
(This special issue belongs to the Section Cell Biology and Pathology)
Diabetes Mellitus: Pharmacological Innovations and Related Therapeutic Benefits submission deadline 31 Mar 2026 | 2 articles | Viewed by 2223 | Submission Open
Keywords: therapy of diabetes mellitus; pharmacological innovations; incretins; GLP-1 receptor agonists; SGLT-2 inhibitors; weight control; diabetes-related cardiovascular risk; non-glycemic benefits of diabetes drugs; diabetes-related technologies; diabetes outcomes
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Immunotherapy and Radiation Therapy for Cancer (2nd Edition)
edited by and Benjamin Spieler
submission deadline 31 Mar 2026 | 2 articles | Viewed by 2108 | Submission Open
Keywords: radiotherapy; immunotherapy; outcome; toxicity; normal tissue; abscopal; tumor; systemic; local; response
(This special issue belongs to the Section Cancer Biology and Oncology)
Imaging Technology for Human Diseases
edited by Emanuele David
submission deadline 31 Mar 2026 | 3 articles | Viewed by 2053 | Submission Open
Keywords: technological advances; imaging; X-ray; mammography; CT; MRI; ultrasound; angiography
(This special issue belongs to the Section Biomedical Engineering and Materials)
Oral Cancer: From Pathophysiology to Novel Therapeutic Approach
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1916 | Submission Open
Keywords: oral cancer and pathophysiology; molecular mechanisms; biomarkers; immunological and targeted therapy; precision medicine and personalized therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Ovarian Cancer
edited by and
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1862 | Submission Open
Keywords: ovarian cancer; biomarkers; cell biology; gene regulation; target therapy; therapeutic resistance; precision medicine
(This special issue belongs to the Section Cancer Biology and Oncology)
Biomarkers and Therapeutic Targets in Gastric Cancer: From Basic Research to Clinical Applications submission deadline 31 Mar 2026 | 1 articles | Viewed by 1853 | Submission Open
Keywords: gastric cancer; tumor microenvironment; gastric cancer metastasis; cancer stem cells; diagnosis and treatment; biomarkers
(This special issue belongs to the Section Cancer Biology and Oncology)
Microbial Metabolites and Their Impact on Gut Homeostasis submission deadline 31 Mar 2026 | 1 articles | Viewed by 1780 | Submission Open
Keywords: intestinal microbiota; microbial metabolites; gut homeostasis; inflammatory response; intestinal epithelial barrier; immune response; diet
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Drug-Resistant Bacterial Infections and Alternative Therapies—2nd Edition
edited by
submission deadline 31 Mar 2026 | 2 articles | Viewed by 1727 | Submission Open
Keywords: alternative agents; antibiotics; phages; endolysins; phytochemicals; drug discovery; nanoparticles; biofilms
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Brain Imaging and Cognitive Deficits in Psychiatric Disorders, 2nd Edition
edited by
submission deadline 31 Mar 2026 | 1 articles | Viewed by 1667 | Submission Open
Keywords: cognitive deficits; psychiatric disorders; schizophrenia; brain imaging
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
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