Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Chronic Pain: From Prevention to Therapeutic Strategies—Second Edition
edited by Isaura Tavares and
submission deadline 28 Feb 2025 | 4 articles | Viewed by 3725 | Submission Open
Keywords: pain pathophysiology; pain prevention; predictive sensory testing; pre- and postoperative chronic pain; new biomarkers in pain; pain management and novel treatments; preemptive analgesia; inflammatory pain
(This special issue belongs to the Section Molecular and Translational Medicine)
Peripheral Artery Disease and Diabetic Foot Ulcer: From Bench to Clinic (2nd Edition) submission deadline 28 Feb 2025 | 3 articles | Viewed by 3701 | Submission Open
Keywords: peripheral artery diseases; diabetic foot ulcer; atherosclerosis; regenerative medicine; inflammatory
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advanced Cancer Diagnosis and Treatment: Second Edition
edited by and Hideshi Ishii
submission deadline 28 Feb 2025 | 5 articles | Viewed by 3541 | Submission Open
Keywords: cancer biology; epigenetics; early detection; diagnosis; biodiagnosis; novel therapeutics; new paradigms
(This special issue belongs to the Section Cancer Biology and Oncology)
From Molecules to Medicine: Deciphering Obesity and Lipid Metabolism for Translational Insights submission deadline 28 Feb 2025 | 3 articles | Viewed by 2782 | Submission Open
Keywords: obesity; insulin resistance; lipid metabolism; drug discovery
(This special issue belongs to the Section Molecular and Translational Medicine)
Oral Cancer: From Pathophysiology to Novel Therapeutic Approaches Volume II submission deadline 28 Feb 2025 | 2 articles | Viewed by 2502 | Submission Open
Keywords: oral carcinogenesis; oral tumorigenesis; oral cancer; OSCC; ICI; mutation; biomarkers; chemoradiation; targeted therapies; cisplatin; preclinical models
(This special issue belongs to the Section Molecular and Translational Medicine)
Soft Electronics Enabled Tissue Engineering and Characterization
edited by Muyang Lin
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2233 | Submission Open
Keywords: soft electronics; tissue engineering; drug delivery; tissue repair; tissue characterization; healthcare
(This special issue belongs to the Section Biomedical Engineering and Materials)
Molecular Mechanisms and Treatment of Rheumatic Diseases
edited by Ruxandra Ionescu and
submission deadline 28 Feb 2025 | 2 articles | Viewed by 2042 | Submission Open
Keywords: rheumatology; immune-mediated rheumatic diseases; biologics; DMARDs; arthritis; lupus; vasculitis; spondyloarthritis; targets
(This special issue belongs to the Section Molecular and Translational Medicine)
Diagnosis, Pathogenesis, Treatment and Prognosis of Glioblastoma
edited by
submission deadline 28 Feb 2025 | 2 articles | Viewed by 1908 | Submission Open
Keywords: glioblastoma; immunotherapy; molecular subtype; radiotherapy; molecular therapy; emerging treatment; drug resistance; MRI; immune surveillance
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Characteristics of Cerebral Ischemia and Their Therapeutic Applications
edited by E-Jian Lee and Shengyang Huang
submission deadline 28 Feb 2025 | 2 articles | Viewed by 1792 | Submission Open
Keywords: cerebral ischemia; molecular mechanisms; pathophysiology; biomarkers; therapeutic strategies; neuroprotection; ischemic stroke; neuro-inflammation; translational research; neuroplasticity; neurophysiology; neuroscience; neuroelectrophysiology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Biomedical and Biochemical Basis of Neurodegenerative Diseases
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1766 | Submission Open
Keywords: neurodegeneration; personalized medicine; biomarkers; diagnosis; treatment
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Next-Generation Sequencing and Proteomics Research for Retinal Diseases
edited by Jayshree Advani
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1673 | Submission Open
Keywords: genomics; proteomics; biomarker; variant interpretation; single-molecule sequencing; epigenome; retinal degeneration; genetics
(This special issue belongs to the Section Molecular and Translational Medicine)
Pharmaceutical Treatments for Typical CKD Comorbidities submission deadline 28 Feb 2025 | 1 articles | Viewed by 1467 | Submission Open
Keywords: natural bioactive compounds; adjuvant treatment; protein energy wasting; mineral bone disorders; metabolic acidosis; hyperhomocysteinemia; uremic sarcopenia; PLADO diet; anemia in CKD
(This special issue belongs to the Section Molecular and Translational Medicine)
Neuroendocrine Neoplasia and Endocrine Tumors: Pathogenic Features, Prognostic Markers and New Therapeutic Approaches
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1413 | Submission Open
Keywords: neuroendocrine tumors; endocrine tumors; somatostatin analogues; carcinoid syndrome; PRRT; mTOR inhibitor; lymph node; neuroendocrine marker; hormone; ki67
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Targeted Therapies for Cancers
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1352 | Submission Open
Keywords: targeted therapy; precision medicine; combination therapy; recurrence mechanisms; immune modulation; cancer stem cell targeting; rna-based therapy; epigenetic therapy; cancer cell metabolism
(This special issue belongs to the Section Cancer Biology and Oncology)
Advancements in Artificial Intelligence (AI) for Cancer Genomics and Genetics submission deadline 28 Feb 2025 | 1 articles | Viewed by 1328 | Submission Open
Keywords: artificial intelligence; cancer; genetics; epigenetics; genomics; epigenomics; gene-environment interaction; cancer diagnosis and prognosis; personalized medicine; drug discovery
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research in Pulmonary Pathophysiology
edited by Ourania S. Kotsiou and Erasmia Rouka
submission deadline 28 Feb 2025 | Viewed by 1218 | Submission Open
Keywords: pathophysiology; aging; disease; injury; microbiome; small airways; pleura; lung cancer; infections; critical care
(This special issue belongs to the Section Cell Biology and Pathology)
Mechanisms and Pharmacological Targets for Pain
edited by Renan F. do Espírito-Santo
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1089 | Submission Open
Keywords: drug discovery; chronic pain; inflammatory pain; mechanisms of action; pain pharmacology; immunomodulation; neuropathic pain
(This special issue belongs to the Section Molecular and Translational Medicine)
Bioactive Peptides and Derivatives as Therapeutic Agents: Potential Applications in Disease Treatment
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1068 | Submission Open
Keywords: bioactive peptide; peptide modification; application; cardiovascular disease; inflammatory disease; digestive disease; neurological disease; drug development
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Recent Advances in Drug Synthesis and Drug Discovery
edited by Ramesh Prasad
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1049 | Submission Open
Keywords: molecular docking; high-throughput virtual screening; computer-aided small molecular drug discovery; machine learning for advancing computational chemistry; molecular dynamics simulation
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Inflammation and Peripheral Nervous System
edited by Nikolett Bódi
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1041 | Submission Open
Keywords: pro- and anti-inflammatory molecules; peripheral nervous system; peripheral neuropathy; neuroinflammation; neuronal environment; neuro-immune interactions; anti-inflammatory therapies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Pollutants and Human Health: Focus on Molecular-Level Research
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 1032 | Submission Open
Keywords: environmental exposure; emerging pollutants; human and ecosystem health; environmental risk assessment; adverse outcome pathways; human risk assessment; endocrine-disrupting chemicals; cardiovascular endocrinology; neurovascular endocrinology; reproductive toxicology
(This special issue belongs to the Section Molecular and Translational Medicine)
Immunometabolic Determinants of Gut–Liver Axis Health submission deadline 28 Feb 2025 | 1 articles | Viewed by 986 | Submission Open
Keywords: gut microbiota; 'entero-hepatic' axis; gut– liver axis; immunometabolism
(This special issue belongs to the Section Immunology and Immunotherapy)
Inflammation Induced Bone Loss: Molecular Basis and Translational Research
edited by Priyanka Kushwaha
submission deadline 28 Feb 2025 | 1 articles | Viewed by 974 | Submission Open
Keywords: rheumatoid arthritis; metabolism induced inflammation; inflammasome; osteoporosis; molecular medicine; disease biology; bone diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Emerging Issues in Retinal Degeneration submission deadline 28 Feb 2025 | 1 articles | Viewed by 850 | Submission Open
Keywords: retinal degeneration; age-related macular degeneration (AMD); retinitis pigmentosa (RP); diabetic retinopathy; gene therapy; stem cell therapy; retinal implants; pharmacological treatments; diagnostic methods; molecular mechanisms; predictive biomarkers; imaging technologies; signaling pathways; oxidative stress; neuroprotection
(This special issue belongs to the Section Cell Biology and Pathology)
New Advances in Chronic Kidney Disease: Biology, Diagnosis and Therapy (2nd Edition) submission deadline 28 Feb 2025 | 1 articles | Viewed by 743 | Submission Open
Keywords: inflammation; kidney biomarkers; kidney injury; chronic kidney disease; dialysis; cardiorenal syndrome risk; CKD anemia; kidney physiopathology; CKD treatment
(This special issue belongs to the Section Cell Biology and Pathology)
Innovative Approaches in In Vitro Skin Models: From Design to Application
edited by
submission deadline 28 Feb 2025 | 1 articles | Viewed by 711 | Submission Open
Keywords: in vitro skin models; tissue engineering; dermatological research; 3D skin bioprinting; skin disease modeling
(This special issue belongs to the Section Biomedical Engineering and Materials)
Cardiovascular Diseases in the Era of Precision Medicine submission deadline 28 Feb 2025 | Viewed by 492 | Submission Open
Keywords: cardiology; precision medicine; cardiovascular diseases; genomics; proteomics; multi-omics; personalized therapy; diagnostic tools; imaging technologies; biosignals
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Induced Pluripotent Stem Cells
edited by
submission deadline 28 Feb 2025 | Viewed by 337 | Submission Open
Keywords: induced pluripotent stem cells; organoids; tissue engineering; biomaterials; reprogramming; iPSC-based cell modelling; cell therapy; microfluidics; drug discovery
(This special issue belongs to the Section Gene and Cell Therapy)
Fatty Liver Disease: From Mechanisms to Therapeutic Approaches
edited by Mirela Baus Lončar
submission deadline 28 Feb 2025 | Viewed by 306 | Submission Open
Keywords: fatty liver; metabolism; animal models of disease; gut– liver– brain axis; therapy
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Exploitation and Development of “Synthetic Lethality” Strategy for Cancer Therapy
edited by Guo Chen
submission deadline 28 Feb 2025 | Viewed by 287 | Submission Open
Keywords: anti-cancer therpies; PARP inhibitors; synthetic lethality
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Gut Virome in Health and Diseases
edited by
submission deadline 28 Feb 2025 | Viewed by 287 | Submission Open
Keywords: gut virome; fecal virome transplantation; phage therapy; microecological regulation; viral dark matter
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Molecular Targets for Biological Therapies of Severe Asthma: Second Edition
edited by
submission deadline 28 Feb 2025 | Viewed by 285 | Submission Open
Keywords: IgE; IL-5; IL-4; IL-13; cytokine receptors; TSLP; monoclonal antibodies; omalizumab; mepolizumab; reslizumab; benralizumab; dupilumab; tezepelumab
(This special issue belongs to the Section Immunology and Immunotherapy)
Adrenal Tumors: From Pathology to Novel Therapeutic Approaches
edited by Anna Babińska
submission deadline 28 Feb 2025 | Viewed by 272 | Submission Open
Keywords: adrenal cortical carcinoma; adrenal cortical adenoma; pheochromocytoma; adrenal incydentaloma; hypercortisolism and metabolic disorders; liquid biopsy and metabolomics.
(This special issue belongs to the Section Cell Biology and Pathology)
Renin-Angiotensin System in Cardiovascular Biology, 2nd Edition submission deadline 28 Feb 2025 | Viewed by 228 | Submission Open
Keywords: renin– angiotensin system (RAS); signaling mechanisms of angiotensin receptors; GPCR; AT1R; AT2R; ACE; ACE2; ACEI; angiotensin II; signal transduction; cardiovascular system; hypertension; atherosclerosis; heart failure; cardiovascular remodeling; osmoregulation; inflammation
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Lung Cancer Precision Oncology Research and Treatments
edited by , and Francesca Colonese
submission deadline 28 Feb 2025 | Viewed by 227 | Submission Open
Keywords: lung; cancer; NSCLC; targeted therapies; immunotherapy; precision oncology; EGFR; KRAS; ALK; ROS1
(This special issue belongs to the Section Cancer Biology and Oncology)
Advanced Research in Cardiovascular and Hemodynamic Monitoring
edited by and Scott T. Benken
submission deadline 28 Feb 2025 | Viewed by 194 | Submission Open
Keywords: vasopressors; hemodynamic monitoring; hypotension; shock; cardiac arrest; heart rate; blood pressure; critical care; intensive care unit
(This special issue belongs to the Section Molecular and Translational Medicine)
New Horizons in Enzyme Inhibitor Discovery: Targets, Design and Evaluation
edited by Chenzhou Hao, Jing Guo, Yin Sun and Tongchao Liu
submission deadline 28 Feb 2025 | Viewed by 186 | Submission Open
Keywords: enzyme inhibitors; drug design; inhibitor screening; medicinal chemistry; targets validation; structure– activity relationship; structure– property relationship
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Pathogenesis, Disease Detection and Novel Therapeutic Approaches for Osteosarcoma
edited by Joanne Tuohy
submission deadline 28 Feb 2025 | Viewed by 168 | Submission Open
Keywords: osteosarcoma; cancer pathogenesis; early disease detection; immunotherapy; targeted therapy; combinatorial therapy; non-surgical therapy; radiation; tumor ablation; personalized patient-specific therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
From Gene Variant to Variant Function: Recent Advances in Cancer Genetics submission deadline 28 Feb 2025 | Viewed by 164 | Submission Open
Keywords: advancements in DNA analysis and variant detection; genetic association studies and the discovery of new cancer-driver genes; diagnostic; prognostic; and predictive genetic cancer biomarkers; locus-specific and comprehensive cancer genetic variation databases; in silico classification of genetic variants; functional analysis of genetic variants; development of mutation-targeted therapies
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Feature Reviews in Cell Death
edited by and Madalina Nistor
submission deadline 28 Feb 2025 | Viewed by 157 | Submission Open
Keywords: cell death pathways; apoptosis; necrosis; biomarkers; therapies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Adiposity, Inflammation, and Metabolic Regulation: Molecular Mechanisms and Therapeutic Strategies
edited by
submission deadline 28 Feb 2025 | Viewed by 147 | Submission Open
Keywords: adipose tissue; inflammation; obesity and its metabolic complications; obesity pathogenesis
(This special issue belongs to the Section Molecular and Translational Medicine)
The Role of the Myofibroblast in Fibrosis and Cancer
edited by Bingrui Li, Xuebin Fu, Xiaodong Zou and Xue Wan
submission deadline 28 Feb 2025 | Viewed by 135 | Submission Open
Keywords: fibroblasts and myofibroblasts; fibrosis (organ and tissue fibrosis); cancer; tissue injury; extracellular matrix
(This special issue belongs to the Section Molecular and Translational Medicine)
Feature Reviews in Target Identification and Drug Discovery
edited by
submission deadline 28 Feb 2025 | Viewed by 112 | Submission Open
Keywords: drug discovery; biological target; bioactive compounds; pharmacology
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Cell Signaling and Molecular Regulation in Neurodegenerative Disease
edited by Shao-Ming Wang
submission deadline 28 Feb 2025 | Viewed by 108 | Submission Open
Keywords: neurological diseases; gene regulation; molecular neurobiology; neurodegenerative disease
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Progress in Neonatal Pulmonary Biology
edited by
submission deadline 28 Feb 2025 | Viewed by 108 | Submission Open
Keywords: neonate; preterm infant; bronchopulmonary dysplasia; animal model; in vivo model; in vitro model; basic research; translational research; respiratory outcome; neurodevelopmental outcome
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Drug Discovery and Development Using Mass Spectrometry
edited by Emily G. Werth, and Lin-zhi Chen
submission deadline 28 Feb 2025 | Viewed by 95 | Submission Open
Keywords: LC/MS; proteomics; protein therapeutics; PTMs; immunocapture; CQAs
(This special issue belongs to the Section Drug Discovery and Development)
Roles of Extracellular Vesicles in Cancer Immunotherapy
edited by Shujing Liu and Zhiyuan Qin
submission deadline 28 Feb 2025 | Viewed by 91 | Submission Open
Keywords: extracellular vesicles; microvesicles; exosomes; cancer biology; cancer immunity; cancer immunotherapy; biomarkers; cancer vaccines; antigen presentation; drug delivery
(This special issue belongs to the Section Cancer Biology and Oncology)
Retinal Vascular Disorders: New Insights into Pathogenesis, Diagnosis and Treatment
edited by Irini P. Chatziralli
submission deadline 28 Feb 2025 | Viewed by 90 | Submission Open
Keywords: diabetic retinopathy; retinal vein occlusion; retinal artery occlusion; sickle-cell retinopathy; optical coherence tomography; widefield imaging; OCT angiography
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Brain Diagnosis and Treatment: From Insights to Innovations
edited by Irene Chaves-Coira and
submission deadline 28 Feb 2025 | Viewed by 88 | Submission Open
Keywords: brain diagnosis and treatment; underlying mechanisms; individualized treatment
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Molecular Research in Breast Cancer submission deadline 28 Feb 2025 | Viewed by 88 | Submission Open
Keywords: breast cancer; apoptosis; signaling pathways; drug resistance; metastasis; cancer stem cells; microRNA; biomarkers; drug target; tumor metabolism; tumor immunity
(This special issue belongs to the Section Molecular and Translational Medicine)
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