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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Gynecological Cancers: Progress and Challenges

edited by

Yi-Fen Chiang

submission deadline 30 Apr 2026 | Viewed by 93 | Submission Open

Keywords: gynecological cancer; therapeutic targets; precision medicine; immunotherapy; drug resistance; biomarkers; molecular mechanisms; natural compound; translational research; adjuvant therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Biomarker, Phenotyping and Therapeutics for Asthma

edited by

Ran Wang

submission deadline 30 Apr 2026 | Viewed by 93 | Submission Open

Keywords: allergy; biomarkers; pathogenesis; exhaled breath; multi-omics; lung physiology; phenotyping; endotypes; therapeutic targets

(This special issue belongs to the Section Molecular and Translational Medicine)

Neuropathology: Understanding Local and Systemic Influence of Disease and Vice-Versa

edited by

Kumar Vaibhav

Pankaj Gaur

, Meenakshi Ahluwalia,

Pankaj Ahluwalia

and Shashi Nandar Kumar

submission deadline 30 Apr 2026 | Viewed by 92 | Submission Open

Keywords: brain pathologies; brain injury; Parkinson’ s disease; Alzheimer’ s disease; stroke; neurodegeneration; hemorrhages; hypoxia; neuroinflammation; translational approaches; oxidative stress; COVID-19; gut– brain axis; systemic influence; immune interaction; synaptic plasticity; ageing; senescence; bone marrow and neuropathology; pesticides; preservatives and environmental contamination; lungs and brain; liver and brain; cardiovascular effect of brain pathology and vice-versa; acute and chronic neuro-immune interaction; therapeutic strategies and intervention; alternative medicines in brain pathologies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Role of Oxidative Stress, Antioxidants, and Gut Microbiota in Obesity and Metabolic Disorders

edited by Lunawati Bennett

submission deadline 30 Apr 2026 | Viewed by 88 | Submission Open

Keywords: obesity; metabolic diseases; antioxidants; gut microbiota; inflammation; reactive oxygen species; cardiovascular diseases

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Rheumatic Diseases: From Pathophysiology to Current and Emerging Therapeutic Approaches

edited by Harriet Morf

submission deadline 30 Apr 2026 | Viewed by 84 | Submission Open

Keywords: rheumatic diseases; molecular mechanisms; treatment; artificial intelligence; cytokine; anti-rheumatic drugs

(This special issue belongs to the Section Immunology and Immunotherapy)

Genetic Research into Human Reproduction

edited by

Efthalia Moustakli

and Athanasios Zikopoulos

submission deadline 30 Apr 2026 | Viewed by 84 | Submission Open

Keywords: reproductive genomics; assisted reproductive technologies (ARTs); reproductive endocrinology; embryo development; reproductive bioinformatics; precision fertility medicine

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Autophagy-Mediated Signalling in Cancer Metastasis and Progression

edited by

Ahmed M. Elshazly

and

David A. Gewirtz

submission deadline 30 Apr 2026 | Viewed by 82 | Submission Open

Keywords: autophagy; cancer; resistance; metastasis; tumor microenvironment; immune evasion

(This special issue belongs to the Section Cancer Biology and Oncology)

Targeting Mast Cells in Human Disease: Bridging Pathology and Therapy

edited by Marianna Criscuolo

submission deadline 30 Apr 2026 | Viewed by 82 | Submission Open

Keywords: mast cell; mast cell activation syndrome; anaphylaxis; mastocytosis; anti-mediator therapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Expanding Opioid Receptor Pharmacology: From Pain Control to Novel Therapeutic Applications in Neurobiology, Immunology, and Psychiatry

edited by

Luca Gentilucci

submission deadline 30 Apr 2026 | Viewed by 81 | Submission Open

Keywords: opioid; pain; mood; stress; addiction; neuropeptides

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Photodynamic Therapy in Cancer—Second Edition

edited by

Shazia Bano

submission deadline 30 Apr 2026 | Viewed by 80 | Submission Open

Keywords: photodynamic therapy; targeted drug delivery and drug release systems; photodiagnosis/tumor imaging; PDT-induced immunogenic cell death; nanomaterials-based combination therapies; theranostics

(This special issue belongs to the Section Cancer Biology and Oncology)

New Advances in the Treatment of Brain Tumors

edited by

Harim Koo

submission deadline 30 Apr 2026 | Viewed by 78 | Submission Open

Keywords: neuro-oncology; brain tumor; cancer therapy; precision medicine; biomarkers; drug delivery; multi-omics; neurosurgery; clinical trials; bioinformatics

(This special issue belongs to the Section Cancer Biology and Oncology)

Novel Directions for Effective Treatments of Malignant Brain Tumors, Particularly Glioblastoma, Indicated by In Vivo Observations

edited by

Jacek M. Kwiecien

submission deadline 30 Apr 2026 | Viewed by 78 | Submission Open

Keywords: glioblastoma; glioblastoma cell invasion; inhibition of glioblastoma cell migration; glioblastoma cell proliferation; killing of glioblastoma cells; white matter inflammation post-neurosurgery; white matter inflammation post-irradiation; cerebral vasogenic edema; treatment of neuroinflammation and vasogenic edema; imaging of glioblastoma

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Diabetic Nephropathy and Diabetic Atherosclerosis (2nd Edition)

edited by

Satyesh K. Sinha

submission deadline 30 Apr 2026 | Viewed by 75 | Submission Open

Keywords: diabetic nephropathy; diabetic atherosclerosis; diabetes; inflammation; oxidative stress; renal and vascular cell dysfunction; basic science; clinical practice; patient outcomes

(This special issue belongs to the Section Molecular and Translational Medicine)

Innovative Therapeutic Strategies and Molecular Mechanisms in Breast Cancer

edited by

Oana Gabriela Trifanescu

and

Laurentia Nicoleta Gales

submission deadline 30 Apr 2026 | Viewed by 73 | Submission Open

Keywords: breast cancer; immunotherapy; medical imaging; biomarkers; translational research

(This special issue belongs to the Section Cancer Biology and Oncology)

Muscular Dystrophy: From Mechanisms to Therapeutic Approaches

edited by

Gisela Gaina

and Marco A.F. Fernandes

submission deadline 30 Apr 2026 | Viewed by 72 | Submission Open

Keywords: muscular dystrophy; genetic diseases; muscle regeneration; therapeutic approaches; molecular diagnosis; in vitro and in vivo models

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

New Advances in Cardiovascular Drugs: In Memory of Professor Akira Endo (2nd Edition)

edited by Alfredo Caturano

submission deadline 30 Apr 2026 | Viewed by 69 | Submission Open

Keywords: cardiovascular drugs; statins; metformin; SGLT2i; laboratory; drug targets; translational research; targeted therapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Diagnosis, Pathogenesis, Treatment and Prognosis of Glioblastoma, 2nd Edition

edited by

Paulo Linhares

submission deadline 30 Apr 2026 | Viewed by 69 | Submission Open

Keywords: glioblastoma; immunotherapy; molecular subtype; radiotherapy; molecular therapy; emerging treatment; drug resistance; MRI; immune surveillance

(This special issue belongs to the Section Cancer Biology and Oncology)

New Perspectives on Systemic Amyloidosis: From Pathophysiology to Therapy

edited by Zoltán Pozsonyi and Katalin Révész

submission deadline 30 Apr 2026 | Viewed by 64 | Submission Open

Keywords: systemic amyloidosis; cardiac amyloidosis; light chain amyloidosis; hereditary transthyretin amyloidosis; wild-type transthyretin amyloidosis; amyloidogenesis; disease-modifying treatments; heart failure with preserved ejection fraction

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Immunological Barriers and Novel Therapeutic Strategies in Pediatric Brain Tumor Immunotherapy

edited by Dalia Haydar

submission deadline 30 Apr 2026 | Viewed by 63 | Submission Open

Keywords: pediatric brain tumors; diffuse intrinsic pontine glioma (DIPG); medulloblastoma; chimeric antigen receptor (CAR) T cells; blood– brain barrier (BBB); tumor microenvironment (TME); immune resistance; adoptive cell therapy; biomarkers; combination immunotherapy

(This special issue belongs to the Section Cancer Biology and Oncology)

The Role of Polyamines in Human Health and Disease—Second Edition

edited by

Kuniyasu Soda

submission deadline 30 Apr 2026 | Viewed by 60 | Submission Open

Keywords: polyamine; spermidine; spermine; health; disease; development

(This special issue belongs to the Section Immunology and Immunotherapy)

Innovative Therapies for Neurodegenerative Diseases

edited by

Rosa María Giráldez-Pérez

, María Victoria Naval,

Javier Garcia-Pardo

and

Maria João Ramalho

submission deadline 10 May 2026 | 1 articles | Viewed by 882 | Submission Open

Keywords: nanotechnology-based therapies; cellular and regenerative therapies; stem cell therapy; gene therapy and RNA interference; protein aggregation inhibitors; neuroinflammation modulators; mitochondrial dysfunction-targeted drugs; preclinical and clinical trials

(This special issue belongs to the Section Gene and Cell Therapy)

“The Power of Light” in Biomedical and Pharmaceutics: New Approaches for Photodynamic Purposes

edited by

Lucinda V. Reis

and

Eurico Lima

submission deadline 20 May 2026 | Viewed by 276 | Submission Open

Keywords: light; photosensitizers; photochemistry; photobiology; photodynamic therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Feature Reviews in Gastrointestinal and Liver Diseases

edited by

Agata Michalak

submission deadline 30 May 2026 | Viewed by 268 | Submission Open

Keywords: gastrointestinal diseases; gut– brain interaction; gut microbiota; inflammatory bowel disease; liver disorders; Crohn’ s disease; cancer; fatty liver disease; malnutrition

(This special issue belongs to the Section Molecular and Translational Medicine)

State-of-the-Art Molecular and Translational Medicine in Poland, 3rd Edition

edited by

Małgorzata Wrzosek

and

Arkadiusz Kocur

submission deadline 31 May 2026 | 6 articles | Viewed by 23403 | Submission Open

Keywords: molecular medicine; molecular mechanisms; disease pathogenesis; genetic variants; gene expression; epigenetics; metabolic disorders; cancer

(This special issue belongs to the Section Molecular and Translational Medicine)

Cell Signaling and Molecular Regulation in Neurodegenerative Disease

edited by Shao-Ming Wang

submission deadline 31 May 2026 | 2 articles | Viewed by 14673 | Submission Open

Keywords: neurological diseases; gene regulation; molecular neurobiology; neurodegenerative disease

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Research in Obesity, 2nd Edition

edited by Zaida Abad-Jiménez and

Teresa Vezza

submission deadline 31 May 2026 | 3 articles | Viewed by 14001 | Submission Open

Keywords: obesity; genetics; molecular pathways; adipose tissue; metabolism; leukocytes; prevention; new targets for treatment; translational studies

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Synaptic Function and Modulation in Health and Disease

edited by Jean-Marie C. Bouteiller

submission deadline 31 May 2026 | 4 articles | Viewed by 13408 | Submission Open

Keywords: synaptic function; synaptic plasticity; neurotransmitter release; receptor dynamics

(This special issue belongs to the Section Molecular and Translational Medicine)

Progress in Neonatal Pulmonary Biology

edited by

Fumihiko Namba

submission deadline 31 May 2026 | 5 articles | Viewed by 12090 | Submission Open

Keywords: neonate; preterm infant; bronchopulmonary dysplasia; animal model; in vivo model; in vitro model; basic research; translational research; respiratory outcome; neurodevelopmental outcome

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Cancer Diagnosis and Treatment: Third Edition

edited by

Takaaki Hirotsu

and Hideshi Ishii

submission deadline 31 May 2026 | 5 articles | Viewed by 11614 | Submission Open

Keywords: cancer biology; epigenetics; early detection; diagnosis; biodiagnosis; novel therapeutics; new paradigms

(This special issue belongs to the Section Cancer Biology and Oncology)

The Role of NK Cells in Cancer Immunotherapy: Mechanisms, Evasion Strategies, and Therapeutic Advances

edited by Maria Eugenia Garcia Rubino

submission deadline 31 May 2026 | 1 articles | Viewed by 10458 | Submission Open

Keywords: NK cells; cancer immunotherapy; tumor evasion; cytotoxicity; CAR-NK; cytokines; IL-2; immunotherapy; tumor microenvironment

(This special issue belongs to the Section Cancer Biology and Oncology)

Vitamin D: Latest Scientific Discoveries in Health and Disease

edited by

Mohamed Abouzid

submission deadline 31 May 2026 | 4 articles | Viewed by 10091 | Submission Open

Keywords: vitamin D; vitamin D metabolites; metabolic pathways; vitamin D receptor; polymorphisms; pathogenesis; vitamin D deficiency

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Organoid, Organ-on-Chip and Advanced 2D/3D Models for Human Tissue Engineering Applications

edited by

Ahmad Salti

submission deadline 31 May 2026 | 6 articles | Viewed by 9346 | Submission Open

Keywords: organoid; organ-on-chip; 2D/3D model; tissue engineering; induced pluripotent stem cells; in vitro model

(This special issue belongs to the Section Biomedical Engineering and Materials)

Skin Diseases: From Molecular Mechanisms to Novel Therapeutic Approaches

edited by

Guangtong Deng

submission deadline 31 May 2026 | 6 articles | Viewed by 8861 | Submission Open

Keywords: skin diseases; cell death; ferroptosis; cuproptosis; melanoma; cancer immunotherapy; psoriasis

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Liver Oncology: Molecular Mechanisms and Therapeutic Innovations

edited by

Rui Caetano Oliveira

, Rui Miguel Martins and

José Guilherme Tralhão

submission deadline 31 May 2026 | 3 articles | Viewed by 8045 | Submission Open

Keywords: liver cancer; hepatocellular carcinoma; cholangiocarcinoma; liver metastases; tumor microenvironment; targeted therapy; immunotherapy; biomarkers; drug resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Animal Models for Neurological Disease Research

edited by

Sreeja Sarasamma

submission deadline 31 May 2026 | 4 articles | Viewed by 7565 | Submission Open

Keywords: animal models; neurological diseases; genetic models; CRISPR/Cas9; transgenic organisms; behavioral analysis; neurodegeneration; single-cell approaches; zebrafish; lamprey; biocomputational approaches; gene therapy; pharmacological interventions; translational neurobiology; disease pathways

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances Research on Nanomedicine

edited by

Rongcheng Han

submission deadline 31 May 2026 | 2 articles | Viewed by 7353 | Submission Open

Keywords: multifunctional nanomaterials; nanomedicine; tumor; theranostics; artificial intelligence (AI); immunotherapy

(This special issue belongs to the Section Biomedical Engineering and Materials)

Mechanisms and Therapeutic Strategies of Brain and Spinal Cord Injury

edited by

Hatice Kumru

and Xabier Urra

submission deadline 31 May 2026 | 5 articles | Viewed by 7091 | Submission Open

Keywords: brain injury; spinal cord injury; stem cells; gene therapy; neuromodulation techniques

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Advances in Pathogenesis and Therapeutics of Gastrointestinal Diseases

edited by

Jinghua Wang

submission deadline 31 May 2026 | 2 articles | Viewed by 6748 | Submission Open

Keywords: gastrointestinal diseases; IBD; IBS; GERD; functional dyspepsia; gut microbiome

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Regulation of Spermatozoa—Second Edition

edited by

Atefeh Najafi

submission deadline 31 May 2026 | 3 articles | Viewed by 6554 | Submission Open

Keywords: spermatogenesis; spermiogenesis; sperm; capacitation; acrosome reaction; hyperactivation; fertilization; male infertility; antioxidants; redox regulation

(This special issue belongs to the Section Cell Biology and Pathology)

Convergence of Allergology and Immunology: Unveiling Mechanistic Insights

edited by

Kinga Lis

submission deadline 31 May 2026 | 3 articles | Viewed by 6136 | Submission Open

Keywords: allergy; hypersensitivity; allergens; immunological mechanisms; immunological diagnostics; immunotherapy

(This special issue belongs to the Section Immunology and Immunotherapy)

Biomedical Devices—Applications for Disease Treatment and Tissue Regeneration

edited by Eleni Papachristou

submission deadline 31 May 2026 | 2 articles | Viewed by 4336 | Submission Open

Keywords: biomedical devices; mesenchymal stem cell; biomedical applications; Tissue engineering

(This special issue belongs to the Section Biomedical Engineering and Materials)

Spinal Muscular Atrophy: Pathogenesis, Diagnosis, Therapeutics and Future Directions

edited by

Dinko Vitezić

Andrej Belančić

and Valentino Rački

submission deadline 31 May 2026 | 1 articles | Viewed by 4219 | Submission Open

Keywords: genetic diseases; neuromuscular disorders; rare diseases; spinal muscular atrophy; survival motor neuron protein

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Non-Invasive Brain Stimulation Techniques and Their Application in the Study of Cognitive Function Physiology and Neuro-Psychiatric Rehabilitation

edited by

Mattia Ferro

Jacopo Lamanna

and Andrea Stefano Moro

submission deadline 31 May 2026 | 3 articles | Viewed by 3901 | Submission Open

Keywords: non-invasive brain stimulation; neurophysiology; cognitive function; depression; schizophrenia

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in the Pathogenesis and Treatment of Heart Failure and Cardiomyopathy

edited by

Andrey Jorge Serra

, Ednei Luiz Antonio, Gianna Móes de Albuquerque-Pontes and Luis Felipe Neves dos Santos

submission deadline 31 May 2026 | 3 articles | Viewed by 3856 | Submission Open

Keywords: cardiomyopathy; cardiac remodeling; heart disease; heart failure; mechanisms; new therapies; targeted therapies

(This special issue belongs to the Section Molecular and Translational Medicine)

The Human Proteinomics in Disease, Diagnostics and Translation into Precision Medicine: Current Status and Future Prospects—2nd Edition

edited by

M. Walid Qoronfleh

submission deadline 31 May 2026 | 3 articles | Viewed by 3837 | Submission Open

Keywords: proteomics; human proteome; systems biology; precision medicine; biomarker(s); disease pathogenesis; diagnostics; mass spectrometry; tandem mass spectrometry; LC-MS/MS; peptides and proteins; multiplex protein analysis; protein network; protein– protein interaction; splice variants; post-translational modifications; omics analysis; data integration; bioinformatics; artificial intelligence; deep learning

(This special issue belongs to the Section Molecular and Translational Medicine)

New Molecular Insights into the Pathogenesis and Drug Development of Neurodegenerative Diseases: 2nd Edition

edited by Aifang Cheng, Beika Zhu and Fulin Ma

submission deadline 31 May 2026 | 2 articles | Viewed by 3523 | Submission Open

Keywords: neurodegenerative diseases; pathogenesis; molecular mechanisms; high-throughput drug screening; drug repurposing; cellular and animal models; brain organoids; mode of action; pharmacological evaluations; preclinical study

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Osteoarthritis: Molecular Pathways and Novel Therapeutic Strategies—2nd Edition

edited by

Antonia Patruno

Teresa Paolucci

Mirko Pesce

and Andrea Pantalone

submission deadline 31 May 2026 | 2 articles | Viewed by 3297 | Submission Open

Keywords: osteoarthritis; cartilage; pain; orthopedics; rehabilitation

(This special issue belongs to the Section Molecular and Translational Medicine)

Advanced Research in Anticancer Inhibitors and Targeted Therapy

edited by

Changmin Peng

and

Hassan Ebrahim

submission deadline 31 May 2026 | 2 articles | Viewed by 3194 | Submission Open

Keywords: histone deacetylases (HDACs); YAP signaling; targeted therapy; oncogenic signaling; biomarker discovery; small-molecule inhibitors; cancer drug resistance; epigenetic therapy

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Advanced Research into Adipose‐Derived Stem Cells

edited by

Anna Barbara Di Stefano

and Mara Franza

submission deadline 31 May 2026 | 1 articles | Viewed by 3024 | Submission Open

Keywords: adipose stem cells; regenerative medicine; stemness; differentiative potential; pre-clinical and clinical applications

(This special issue belongs to the Section Molecular and Translational Medicine)

Biological Role of Oxidative Stress in Inflammatory Processes

edited by

Magdalena Paulina Kasprzak

submission deadline 31 May 2026 | 1 articles | Viewed by 2817 | Submission Open

Keywords: oxidative stress; redox balance; antioxidants; NRF2; microbiota; bilirubin; Tlr4; inflammation

(This special issue belongs to the Section Cell Biology and Pathology)

Displaying special issue 401-450 on page 9 of 15.

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