Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Nanotechnology in Pharmaceuticals
edited by Pratap Basim, and
submission deadline 31 Jan 2026 | Viewed by 217 | Submission Open
Keywords: nanotechnology; drug delivery; diagnostics; theranostics; biomimetics; nanocarriers; targeted delivery; routes of administration
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Additive Manufacturing in Biomedical Applications
edited by
submission deadline 31 Jan 2026 | Viewed by 193 | Submission Open
Keywords: additive manufacturing; scaffolds; implant; anatomical models; in vivo; in vitro; surface texture; geometrical accuracy; biomaterials; surface roughness
(This special issue belongs to the Section Biomedical Engineering and Materials)
Urothelial Carcinoma: Role of Biomarkers in Diagnosis, Prognosis and Treatment (2nd Edition)
edited by Ioannis Zachos and
submission deadline 31 Jan 2026 | Viewed by 191 | Submission Open
Keywords: urothelial carcinoma; biomarker; diagnosis; treatment; prognosis
(This special issue belongs to the Section Molecular and Translational Medicine)
Autonomic Disorders: From Mechanisms to Therapeutic Approaches
edited by Svetlana Blitshteyn
submission deadline 31 Jan 2026 | Viewed by 165 | Submission Open
Keywords: autonomic disorders; autonomic dysfunction; dysautonomia; orthostatic intolerance; therapeutics
(This special issue belongs to the Section Molecular and Translational Medicine)
Cell Metabolism in Brain Physiology and Pathology: From Molecular Mechanisms to Therapeutic Targets
edited by and Mayra Colardo
submission deadline 31 Jan 2026 | Viewed by 165 | Submission Open
Keywords: autophagy; energy homeostasis; glucose metabolism; lipids; metabolism; nervous system; oxidative stress; protein metabolism; neurodegeneration; neurodevelopment
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Organisms as Diagnostic Technologies: Harnessing Life for Sensing Mechanisms
edited by and Hideshi Ishii
submission deadline 31 Jan 2026 | Viewed by 159 | Submission Open
Keywords: biological sensors; diagnostic technologies; diagnostic technologies; biological sensing mechanisms; conversion of biological signals; bio-interfaces
(This special issue belongs to the Section Biomedical Engineering and Materials)
The Pleiotropic Effects of Statins: Anti-Inflammatory, Anti-Coagulant, and Anti-Proliferative Properties
edited by
submission deadline 31 Jan 2026 | Viewed by 150 | Submission Open
Keywords: hydroxymethylglutaryl-CoA reductase inhibitors; pharmacoepidemiology; anti-inflammatory properties; anti-coagulant properties; anti-proliferative properties
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Extracellular Vesicles and Exosomes as Therapeutic Agents—2nd Edition submission deadline 31 Jan 2026 | Viewed by 145 | Submission Open
Keywords: extracellular vesicles; exosomes; therapeutics; drug delivery; bioengineering
(This special issue belongs to the Section Cell Biology and Pathology)
Metabolic Disorders and Their Complications: From Molecular Mechanisms to Therapeutic Perspectives submission deadline 31 Jan 2026 | Viewed by 140 | Submission Open
Keywords: metabolism; diabetes; obesity; nutrition; AMPK and mTOR
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Signal Peptides in Health and Disease: Molecular Mechanisms and Therapeutic Potential
edited by
submission deadline 31 Jan 2026 | Viewed by 136 | Submission Open
Keywords: signal peptides; protein targeting; protein trafficking; therapeutic peptides; synthetic signal peptides; signal recognition particle; drug delivery system; biomarker discovery
(This special issue belongs to the Section Molecular and Translational Medicine)
Biologics for Bone and Soft Tissue Regeneration: What Is New, What Is True—Second Edition submission deadline 31 Jan 2026 | Viewed by 133 | Submission Open
Keywords: regenerative medicine; stem cells; exosomes; musculoskeletal injuries; osteoarthritis; tissue regeneration; tissue engineering; biologics; bone; soft tissue
(This special issue belongs to the Section Biomedical Engineering and Materials)
Advanced Research in Liver Diseases
edited by
submission deadline 31 Jan 2026 | Viewed by 132 | Submission Open
Keywords: liver; obesity; alcohol; oxidative stress; nutrients; vitamins; metabolism; homeostasis
(This special issue belongs to the Section Cell Biology and Pathology)
Molecular Signatures and Therapeutic Strategies in Urological Cancers
edited by Haoyue Sheng
submission deadline 31 Jan 2026 | Viewed by 124 | Submission Open
Keywords: urological cancers; molecular signatures; precision medicine; non-coding RNAs; tumor microenvironment
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in 3D Printing for Drug Delivery Systems
edited by , Cristina Manuela Drăgoi and Alina Crenguța Nicolae
submission deadline 31 Jan 2026 | Viewed by 124 | Submission Open
Keywords: 3D printing; drug delivery systems; personalized medicine; pharmaceutical engineering; controlled release
(This special issue belongs to the Section Biomedical Engineering and Materials)
Biologic Drugs: The Evolution of Asthma Therapeutics submission deadline 31 Jan 2026 | Viewed by 123 | Submission Open
Keywords: severe asthma; IgE; IL-4; IL-5; IL-13; TSLP; monoclonal antibodies
(This special issue belongs to the Section Immunology and Immunotherapy)
Cancer Pharmacology
edited by Zhi Shi
submission deadline 31 Jan 2026 | Viewed by 120 | Submission Open
Keywords: cancer pharmacology; anticancer drug; cancer chemotherapy; targeted therapy; cancer immunotherapy; combination therapy; drug resistance
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Antibody Responses to Viral Infections: Insights from Structural Biology
edited by Pragati Agnihotri and
submission deadline 31 Jan 2026 | Viewed by 120 | Submission Open
Keywords: crystal structure; virus– antibody complexes; broadly neutralizing antibodies; immunology; epitope mapping
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Tumour Angiogenesis and Anti-Angiogenic Therapy submission deadline 31 Jan 2026 | Viewed by 120 | Submission Open
Keywords: tumour angiogenesis; vascularization; endothelial cells; pericytes; vascular endothelial growth factor (VEGF); bevacizumab; micro vessel density; anti-angiogenic therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Shock Syndromes: Pathophysiology, Diagnostics and Emerging Therapeutics Across the Clinical Spectrum submission deadline 31 Jan 2026 | Viewed by 116 | Submission Open
Keywords: shock; critical illness; cardiogenic shock; septic shock; hypovolemic shock; obstructive shock; inflammation; hemodynamics; artificial intelligence in medicine; precision medicine; vasopressors; mechanical circulatory support; diagnostics
(This special issue belongs to the Section Molecular and Translational Medicine)
Cell Cycle in Normal Physiology and Disease
edited by
submission deadline 31 Jan 2026 | Viewed by 114 | Submission Open
Keywords: cell cycle; DNA replication; DNA damage; cyclins; cyclin-dependent kinases (CDKs); CDK inhibitors; cell proliferation; cancer
(This special issue belongs to the Section Cell Biology and Pathology)
New Treatments for Colorectal Cancer
edited by
submission deadline 31 Jan 2026 | Viewed by 114 | Submission Open
Keywords: biomarkers; signaling pathway; chemotherapy; reactive oxygen species; angiogenesis
(This special issue belongs to the Section Cancer Biology and Oncology)
Advancements in Research on Pancreatic Cancer: From Biomarkers to Targeted Therapies
edited by
submission deadline 31 Jan 2026 | Viewed by 112 | Submission Open
Keywords: pancreatic cancer; novel biomarkers; diagnostic techniques; therapeutic approaches
(This special issue belongs to the Section Cancer Biology and Oncology)
Risk Factors and Molecular Mechanisms in Diabetes and Cardiovascular Complications
edited by
submission deadline 31 Jan 2026 | Viewed by 110 | Submission Open
Keywords: diabetes; cardiovascular disease; atherosclerosis; ischemic heart disease; insulin resistance; risk factors; molecular mechanisms  
(This special issue belongs to the Section Endocrinology and Metabolism Research)
New Advances in Neuroprotective Agent
edited by
submission deadline 31 Jan 2026 | Viewed by 106 | Submission Open
Keywords: mitochondrial disfunction; antioxidant molecules; gene therapy; stem cell; nanomedicine; cellular reprogramming
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Pharmacological Mechanisms and Target Discovery in Lung Injury-Driven Fibrosis: From Molecular Pathways to Preclinical Innovation
edited by
submission deadline 31 Jan 2026 | Viewed by 104 | Submission Open
Keywords: lung injury and fibrosis; pharmacological mechanisms; target discovery; mechanistic drivers; target identification; drug design; preclinical models
(This special issue belongs to the Section Molecular and Translational Medicine)
Pharmacogenetics and Pharmacogenomics: Driving Forces in Modern Precision Medicine
edited by Miriam Saiz-Rodríguez and Dora Koller
submission deadline 31 Jan 2026 | Viewed by 104 | Submission Open
Keywords: pharmacogenetics; pharmacogenomics; precision medicine; polygenic risk scores; phenoconversion; drug response; genetic biomarkers; personalized therapy; underrepresented populations; clinical implementation
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Emerging Insights into HIV: Second Edition
edited by , Antonios Papadopoulos and
submission deadline 31 Jan 2026 | Viewed by 103 | Submission Open
Keywords: HIV/AIDS; antiretroviral treatment; comorbidities; co-infection; neuroHIV
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Molecular Pathways and Their Clinical Implications in Ischemic Heart Disease and Heart Failure: From Pathophysiology to Therapeutic Strategies
edited by and Efstratios Karagiannidis
submission deadline 31 Jan 2026 | Viewed by 101 | Submission Open
Keywords: ischemic heart disease; heart failure; molecular mechanisms; biomarkers; targeted therapy; precision medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Cancer Metastasis Modeling: From Mechanisms to Therapies
edited by
submission deadline 31 Jan 2026 | Viewed by 99 | Submission Open
Keywords: cancer metastasis; tumor microenvironment; extracellular matrix; metastasis models; drug resistance; in vivo imaging; molecular mechanisms; targeted therapy; computational modeling; and antibody-drug conjugates
(This special issue belongs to the Section Cancer Biology and Oncology)
Mechanisms and Novel Therapeutic Approaches for Nephrology
edited by
submission deadline 31 Jan 2026 | Viewed by 99 | Submission Open
Keywords: chronic kidney disease; acute kidney injury; therapeutics; molecular mechanisms; biomarkers; drug discovery; regenerative medicine; precision medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Exploring Antiangiogenic Agents in Drug Discovery: Molecular Mechanisms and Therapeutic Implications submission deadline 31 Jan 2026 | Viewed by 97 | Submission Open
Keywords: angiogenesis; antiangiogenic agents; signaling pathway; preclinical model; drug discovery; computational tools
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Bioactive Lipids in Disease: Diagnosis, Prognosis, and Pathophysiology
edited by
submission deadline 31 Jan 2026 | Viewed by 96 | Submission Open
Keywords: bioactive lipids; eicosanoids; endocannabinoids; lysophospholipids; sphingolipids; oxysterols; bile acids; lipidomics; pathophysiology; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma
edited by Julia Federspiel, and
submission deadline 31 Jan 2026 | Viewed by 93 | Submission Open
Keywords: head and neck oncology 3D tumor models; cancer-associated fibroblasts; phototherapy; exosomes
(This special issue belongs to the Section Cancer Biology and Oncology)
The Latest Advancements in Tumor Drug Delivery Systems
edited by
submission deadline 31 Jan 2026 | Viewed by 90 | Submission Open
Keywords: tumor targeting; gene delivery; biomemetic drug delivery; cancer-targeting nanorobot; specific cancer cell targeting; antitumor immunotherapy; cancer nanovaccine; tumor-suppressing nanoenzyme
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Microbiota and Immunity in Cancers
edited by Davide Frumento
submission deadline 31 Jan 2026 | Viewed by 82 | Submission Open
Keywords: immunology; cancer; microbiota; immunotherapy; probiotics; oncology
(This special issue belongs to the Section Molecular and Translational Medicine)
Nanoparticles in Medicine: The Potential of “Empty” Nanoparticles and Future Challenges
edited by Cuthbert O Simpkins and
submission deadline 31 Jan 2026 | Viewed by 79 | Submission Open
Keywords: nanoparticles; empty nanoparticles; nanoparticle technology
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Dopamine in Health and Disease (3rd Edition)
edited by
submission deadline 31 Jan 2026 | Viewed by 75 | Submission Open
Keywords: dopamine; disease models; mitochondria; Parkinson’ s disease; schizophrenia
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Innovations in Understanding and Treating Pancreatic Diseases
edited by
submission deadline 31 Jan 2026 | Viewed by 69 | Submission Open
Keywords: pancreatic cancer; pancreatitis; tumor microenvironment; epithelial– mesenchymal transition (EMT); metastasis; liver metastatic niche; immunotherapy; biomarkers; targeted therapies; inflammation and fibrosis
(This special issue belongs to the Section Cell Biology and Pathology)
Advances in Cancer Cell Metabolism and Tumor Microenvironment
edited by
submission deadline 31 Jan 2026 | Viewed by 68 | Submission Open
Keywords: metabolism; cancer; immune cells; tumor microenvironment; cancer-associated organ failure; cancer therapeutics
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Emerging Therapeutic Approaches to Head and Neck Cancer
edited by and Daria Maria Filippini
submission deadline 31 Jan 2026 | Viewed by 66 | Submission Open
Keywords: head and neck cancer; HPV-related head and neck cancer; EBV-related nasopharyngeal cancer; prognostic biomarkers; predictive biomarkers; novel combinations; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Allergies and Autoimmunity
edited by
submission deadline 31 Jan 2026 | Viewed by 66 | Submission Open
Keywords: asthma; arthritis; diabetes; inflammatory bowel disease; dermatomyositis; Sjö gren's syndrome; systemic lupus erythematosus; psoriasis; multiple sclerosis
(This special issue belongs to the Section Cell Biology and Pathology)
The Prefrontal Cortex in Cognition and Diseases
edited by
submission deadline 31 Jan 2026 | Viewed by 59 | Submission Open
Keywords: executive function; working memory; behavioral inhibition; attention; anxiety; social behavior; ADHD (attention-deficit hyperactivity disorder); schizophrenia; MDD (major depressive disorder); AD (Alzheimer's disease); PD (Parkinson’ s disease)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Biochemical and Molecular Perspectives on Engineered Nanoparticles for Cancer Therapy submission deadline 10 Feb 2026 | Viewed by 182 | Submission Open
Keywords: cancer; oxidative stress; engineered nanoparticles (ENPs); drug delivery; biochemical processes; ferroptosis; apoptosis; cell death; molecular interactions; tumor microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Innovations in Bone and Craniofacial Tissue Engineering: From Biomaterials and Mechanobiology to Clinical Applications
edited by Zhekai Hu
submission deadline 15 Feb 2026 | Viewed by 149 | Submission Open
Keywords: bone tissue engineering; craniofacial regeneration; biomaterials and scaffolds; stem cells and exosomes; mechanobiology and orthodontic forces; osteoimmunology; oxidative stress modulation; gene/drug delivery; translational research; periodontal and alveolar bone regeneration
(This special issue belongs to the Section Biomedical Engineering and Materials)
Emerging Trends in Malignant Mesothelioma
edited by Yuan Xu
submission deadline 20 Feb 2026 | Viewed by 257 | Submission Open
Keywords: mesothelioma; asbestos; novel therapeutic strategies; treatment resistance; multi-omics analysis
(This special issue belongs to the Section Cancer Biology and Oncology)
Autophagic Signatures in Health and Disease: Molecular Insights and Clinical Applications submission deadline 20 Feb 2026 | Viewed by 102 | Submission Open
Keywords: autophagy; pathology; physiology; therapy; methods
(This special issue belongs to the Section Cell Biology and Pathology)
Obstructive Sleep Apnea: Mechanisms, Comorbidities, and Optimization of Emerging and Established Therapies submission deadline 25 Feb 2026 | 3 articles | Viewed by 4465 | Submission Open
Keywords: obstructive sleep apnea; sleep-disordered breathing; pathophysiology; cardiometabolic comorbidities; precision medicine; CPAP; sleep diagnostics; biomarkers; neurocognitive impairment; new therapies
(This special issue belongs to the Section Molecular and Translational Medicine)
Current Trends in Diabetic Foot Disease
edited by Xuefeng Yu
submission deadline 27 Feb 2026 | Viewed by 207 | Submission Open
Keywords: diabetes; diabetic foot; endocrinology; metabolic disease
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Pathology, Complications and Prognosis of Type 1 Diabetes
edited by Maurizio Delvecchio
submission deadline 27 Feb 2026 | Viewed by 58 | Submission Open
Keywords: type 1 diabetes mellitus; autoimmune β -cell destruction; diabetic complications; microvascular and macrovascular damage; diabetic ketoacidosis; glycemic control; disease prognosis; immunopathogenesis
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Advanced Research of Gut Microbiota in Health and Diseases—2nd Edition submission deadline 28 Feb 2026 | 8 articles | Viewed by 20370 | Submission Open
Keywords: microbiota; gut; dysbiosis; gut microbiome; pathological conditions; metabolic disorders; autoimmune disease; inflammatory disorders; degenerative diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
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