Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Novel Progress in Cancer Immunotherapy
edited by
submission deadline 31 Dec 2024 | Viewed by 249 | Submission Open
Keywords: immune checkpoint blockers; CAR-T; solid tumor; liquid tumor; cancer therapy; immunology
(This special issue belongs to the Section Cancer Biology and Oncology)
Recent Advances in Craniofacial Pain and Headaches—Second Edition submission deadline 31 Dec 2024 | Viewed by 227 | Submission Open
Keywords: craniofacial pain; headache; migraine; painful temporomandibular disorders; orofacial pain; biomedical advances; treatment; assessment; innovation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Cholinergic System Neurodegeneration: Novel Pharmacotherapy
edited by and Paula Moyano
submission deadline 31 Dec 2024 | Viewed by 224 | Submission Open
Keywords: cholinergic system; neurodegeneration; acetylcholine; cholinergic neurons; cholinergic pathologies; therapeutic approaches
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
The Molecular Mechanisms Underlying the Activation and Regulation of Signaling Pathways in Cancer
edited by
submission deadline 31 Dec 2024 | Viewed by 211 | Submission Open
Keywords: activation; regulation; signaling pathways; cancer; post-translational modifications; molecular regulators; therapeutic targets; signaling pathway dysregulation
(This special issue belongs to the Section Molecular and Translational Medicine)
Poor Ovarian Response: From Bench to Bedside submission deadline 31 Dec 2024 | Viewed by 209 | Submission Open
Keywords: assisted reproduction; in vitro fertilization (IVF); poor ovarian response (POR); ovarian functionality; ovarian aging; ovarian stimulation; adjuvant treatment; biomarkers
(This special issue belongs to the Section Molecular and Translational Medicine)
Immunosuppressive Treatment in Glomerular Diseases
edited by Henry H.L. Wu and Rajkumar Chinnadurai
submission deadline 31 Dec 2024 | Viewed by 208 | Submission Open
Keywords: immunosuppressive treatment; glomerular diseases; nephrology
(This special issue belongs to the Section Immunology and Immunotherapy)
New Trends in Cancer Immunotherapy
edited by Markella Zannikou
submission deadline 31 Dec 2024 | Viewed by 207 | Submission Open
Keywords: tumor microenvironment; cancer vaccines; tumor-infiltrating lymphocytes; combination therapy; BITEs; checkpoint inhibitors; CAR T cell therapy; NK cells; antigen presenting cells; tumor associated antigens
(This special issue belongs to the Section Immunology and Immunotherapy)
Neurotransmitters in Health and Diseases
edited by and Krisztina Csabafi
submission deadline 31 Dec 2024 | Viewed by 193 | Submission Open
Keywords: neurotransmitters; GABA; dopamine; glutamate; acetylcholine; neurohormones; neuromodulators
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advancements in the Treatment of Mesothelioma
edited by
submission deadline 31 Dec 2024 | Viewed by 177 | Submission Open
Keywords: mesothelioma; targeted therapy; diagnostics; checkpoint inhibitors; immunotherapy; chemotherapy; combination therapy
(This special issue belongs to the Section Molecular and Translational Medicine)
Potential Off-Target Actions of Small-Molecule Modulators Initially Designed for Special Functions
edited by
submission deadline 31 Dec 2024 | Viewed by 177 | Submission Open
Keywords: small-molecule modulators; off-target effects; ion channel modulation; pharmacological impact
(This special issue belongs to the Section Cell Biology and Pathology)
The Role of MicroRNAs in Adult Skeletal Muscle
edited by Ivan J. Vechetti
submission deadline 31 Dec 2024 | Viewed by 176 | Submission Open
Keywords: skeletal muscle; miRNAs; regeneration; aging; atrophy; hypertrophy
(This special issue belongs to the Section Molecular and Translational Medicine)
Mastocytosis, MCAS, and Related Disorders: From Mechanisms to Therapeutic Approaches
edited by Marianna Criscuolo
submission deadline 31 Dec 2024 | Viewed by 163 | Submission Open
Keywords: mast cell; alpha tryptasemia; hymenoptera venom; mastocytosis; anti-mediator therapy; tyrosine kinase inhibitors; allogeneic transplant
(This special issue belongs to the Section Immunology and Immunotherapy)
Advances in Cancer Biology and Experimental Anticancer Therapies (2nd Edition)
edited by and
submission deadline 31 Dec 2024 | Viewed by 162 | Submission Open
Keywords: cancer biology; experimental anticancer therapies; immunotherapy; immunotoxins; signalling pathways; targeted therapies
(This special issue belongs to the Section Cancer Biology and Oncology)
Hepato-Pancreato-Biliary Cancers: Pathogenesis, Comorbidities and Therapy Updated submission deadline 31 Dec 2024 | Viewed by 161 | Submission Open
Keywords: liver; bile; cancer; microbiome; pathogenesis; MiRNA; jaundice; disease; therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Immune Cell Biology: Insights from Molecular Perspectives
edited by
submission deadline 31 Dec 2024 | Viewed by 156 | Submission Open
Keywords: immune cell biology; cell signaling cascades; autoimmune disorders; immunoinflammatory pathways; hematological disorders
(This special issue belongs to the Section Cell Biology and Pathology)
Recent Advances in Diagnosis and Therapeutic Strategies in Intraocular Inflammation
edited by
submission deadline 31 Dec 2024 | Viewed by 152 | Submission Open
Keywords: biomarker; diagnosis; immune pharmacology; immune regulation; immune system; infection; uveitis; therapy
(This special issue belongs to the Section Immunology and Immunotherapy)
Biomarkers in Metabolic Disorders, Obesity and Type 2 Diabetes Mellitus
edited by and Anna Maria Różańska-Walędziak
submission deadline 31 Dec 2024 | Viewed by 147 | Submission Open
Keywords: metabolic disorders; obesity; type 2 diabetes mellitus; bariatric surgery; laboratory parameters
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Extracellular Vesicles and Lipid Nanoparticles in Cardiovascular Diseases
edited by Junlang Li
submission deadline 31 Dec 2024 | Viewed by 147 | Submission Open
Keywords: extracellular vesicles; exosomes: lipid nanoparticles; cardiovascular diseases; RNA delivery
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Molecular Research of Neurodegenerative and Psychiatric Diseases, 2nd Edition submission deadline 31 Dec 2024 | Viewed by 145 | Submission Open
Keywords: neurodegenerative disorders; psychiatric diseases; biomarkers; therapeutic targets; omics approaches; molecular pathways; cell biology; animal models; clinical studies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Advanced Research on the Role of Biogenic Amines in Physiological and Pathological Conditions submission deadline 31 Dec 2024 | Viewed by 143 | Submission Open
Keywords: biogenic amines; memory; synapse; depression; anxiety; schizophrenia; glioma and neurodegenerative diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Progress in Cardiovascular Pharmacology submission deadline 31 Dec 2024 | Viewed by 135 | Submission Open
Keywords: cardiovascular diseases; cardiovascular pharmacology; target therapies; molecular pharmacology; heart failure; preventive cardiology; atherosclerosis
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Innate Immunity Orchestration in Lung Health and Diseases, 2nd Edition
edited by
submission deadline 31 Dec 2024 | Viewed by 132 | Submission Open
Keywords: innate immune cells; neutrophils; NETs; NETosis; macrophages; phagocytosis; innate lymphoid cells; epithelial cells; lung inflammation; lung cancer; immunotherapy
(This special issue belongs to the Section Immunology and Immunotherapy)
Progress in Immunopharmacy
edited by and Shun-Hua Chen
submission deadline 31 Dec 2024 | Viewed by 120 | Submission Open
Keywords: immunopharmacy; immunopharmacology; immunomodulation; pharmacological intervention; immunotherapy; drug– immune system interaction; vaccine development; personalized pharmacotherapy
(This special issue belongs to the Section Immunology and Immunotherapy)
Role of Microbiota in Colonic Inflammation and Colon Cancer
edited by
submission deadline 31 Dec 2024 | Viewed by 117 | Submission Open
Keywords: microbiota; colon inflammation; colon cancer; molecular mechanism; clinical treatment
(This special issue belongs to the Section Microbiology in Human Health and Disease)
Advances of Gut Microbiota in Gastroenterology and Hepatology submission deadline 31 Dec 2024 | Viewed by 107 | Submission Open
Keywords: gut microbiota; hepatology; gastroenterology; inflammatory bowel disease; colorectal cancer; nutrition; nature products
(This special issue belongs to the Section Molecular and Translational Medicine)
Immunological Mechanisms of Host Defense and Inflammation: Insights into Immune Responses and Homeostasis
edited by Rémi Safi
submission deadline 31 Dec 2024 | Viewed by 106 | Submission Open
Keywords: antimicrobial defense; interferon; pro-inflammatory mediators; lipopolysaccharide; immunometabolism; virulence factors; host lipid metabolism; infection; toll like receptors; cytokines
(This special issue belongs to the Section Immunology and Immunotherapy)
Extracellular Vesicles in Cancer Progression and Therapeutic Response
edited by
submission deadline 31 Dec 2024 | Viewed by 103 | Submission Open
Keywords: nanoparticles; exosomes; engineered EV; immune checkpoint blockade; cancer; microenvironment
(This special issue belongs to the Section Cancer Biology and Oncology)
Applications and Perspectives of Cold Electric Discharge Plasmas in Biomedicine and Bioengineering submission deadline 31 Dec 2024 | Viewed by 100 | Submission Open
Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Understanding of the Role of Synuclein Family Members in Health and Disease: Third Edition
edited by
submission deadline 31 Dec 2024 | Viewed by 99 | Submission Open
Keywords: synuclein family; alpha-synuclein; beta-synuclein; gamma-synuclein; physiological functions of synucleins; synucleins and lipids; function of synucleins outside of the nervous system; synuclein-associated pathology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
DNA Methylation Profiling for the Classification and Diagnosis of Tumors
edited by
submission deadline 31 Dec 2024 | Viewed by 99 | Submission Open
Keywords: DNA methylation; tumors; central nervous system; soft tissues; haematolymphoid tumors; diagnostic tool
(This special issue belongs to the Section Gene and Cell Therapy)
Molecular Mechanisms and Novel Therapies for Brain Injury: 2nd Edition
edited by
submission deadline 31 Dec 2024 | Viewed by 92 | Submission Open
Keywords: stroke; spinal cord injury; traumatic brain injury; seizure; brain tumors; neurodegeneration; neuroinflammation; blood– brain barrier disruption; neuroprotection; drug discover; mechanism of action; target validation
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
New Insights Into Non-Alcoholic Fatty Liver Diseases submission deadline 31 Dec 2024 | Viewed by 91 | Submission Open
Keywords: NAFLD; non-alcoholic fatty liver disease; metabolic pathways; molecular mechanisms; genetic polymorphisms; population disparities; risk stratification; clinical challenges; nutritional interventions; triglyceride glucose index
(This special issue belongs to the Section Molecular and Translational Medicine)
Crohn’s Disease, the Microbiome and Infections: Mechanisms, Novel Diagnostic and Therapeutic Strategies for Pathology submission deadline 31 Dec 2024 | Viewed by 86 | Submission Open
Keywords: infections; gut microbiome; Mycobacterium paratuberculosis; Crohn’ s disease; ulcerative colitis; innate immunity; diagnostics culture; molecular
(This special issue belongs to the Section Cell Biology and Pathology)
Microbiota-Derived Signals in Human Diseases
edited by
submission deadline 31 Dec 2024 | Viewed by 83 | Submission Open
Keywords: microbiota-derived signals; metabolic diseases; inflammatory diseases
(This special issue belongs to the Section Molecular and Translational Medicine)
Amyloid-β Dynamics and Neurodegeneration: Mechanistic Insights and Therapeutic Strategies
edited by
submission deadline 31 Dec 2024 | Viewed by 82 | Submission Open
Keywords: Alzheimer’ s disease (AD); amyloid-β clearance; brain and periphery; cerebral amyloid angiopathy (CAA)
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
New Insights into the Diagnosis and Treatment of Breast Cancer submission deadline 31 Dec 2024 | Viewed by 77 | Submission Open
Keywords: Breast cancer; prognostic; medical imaging; chemotherapy; immunotherapy; diagnostics; screening
(This special issue belongs to the Section Cancer Biology and Oncology)
Nanomedicine Applications in the Diagnosis and Treatment of Neurodegenerative Diseases
edited by Sudipta Senapati
submission deadline 31 Dec 2024 | Viewed by 77 | Submission Open
Keywords: neurodegenerative diseases; nanomedicine; blood– brain barrier permeability; early diagnosis and treatment; biosensing and bioimaging
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Polyamines in Human Diseases
edited by
submission deadline 31 Dec 2024 | Viewed by 76 | Submission Open
Keywords: polyamine; spermidine; spermine; health; disease; development
(This special issue belongs to the Section Immunology and Immunotherapy)
Innovations in Nanomedicine for Disease Management
edited by Anna Valentino and
submission deadline 31 Dec 2024 | Viewed by 70 | Submission Open
Keywords: nanomedicine; nanoparticles; smart drug delivery; personalized medicine; minimally invasive treatments; gene therapy; regenerative medicine
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Diseases and Regeneration for Muscle, Joint and Bone
edited by , Sung-Yen Lin and Cheng-Jung Ho
submission deadline 31 Dec 2024 | Viewed by 70 | Submission Open
Keywords: arthritis; bone; epidemiology; joint; muscle; osteoporosis; pathogenesis; sarcopenia; treatment
(This special issue belongs to the Section Molecular and Translational Medicine)
Pathogenesis, Diagnosis, and Treatment of Cardiomyopathy: Special Focus on Infiltrative Cardiomyopathy
edited by Shanat Baig
submission deadline 31 Dec 2024 | Viewed by 62 | Submission Open
Keywords: infiltrative cardiomyopathy; amyloidosis; sarcoidosis; hemochromatosis; Fabry disease; glycogen storage disorders; lysosomal storage disorders; Danon disease
(This special issue belongs to the Section Cell Biology and Pathology)
Biliary Tract Cancer: From Molecular Mechanism to Therapeutic Perspectives
edited by Jing Han Hong
submission deadline 31 Dec 2024 | Viewed by 61 | Submission Open
Keywords: biliary tract cancers; molecular mechanisms; drug discovery; therapeutic vulnerabilities; translational science
(This special issue belongs to the Section Molecular and Translational Medicine)
Applications and Developments of Metal-Based Drugs
edited by
submission deadline 31 Dec 2024 | Viewed by 60 | Submission Open
Keywords: anticancer; anti-infectious diseases; nuclear medicines; immunotherapeutic; drug delivery; organometallic complexes; metal-based drugs; metallotherapeutic drugs
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Advances in Cardiac Fibrosis and Inflammation: Molecular Mechanisms and Therapeutic Frontiers
edited by Melis Olcum
submission deadline 31 Dec 2024 | Viewed by 51 | Submission Open
Keywords: cardiac fibrosis; inflammation; epigenetics; cytokines; inflammasomes; extracellular vesicles; genetic factors; cardiomyopathies; extracellular matrix; fibroblast activation; cardiac biomarker; immune cells; chemokines; heart; in vivo models; in vitro models
(This special issue belongs to the Section Molecular and Translational Medicine)
Ovarian Cancer: From Mechanisms to Novel Target Therapies
edited by
submission deadline 1 Jan 2025 | Viewed by 228 | Submission Open
Keywords: epithelial ovarian cancer; relapsed disease; subtypes; therapeutic resistance; metastasis
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art and Novel Approaches in Molecular and Translational Medicine in Europe submission deadline 15 Jan 2025 | 6 articles | Viewed by 13771 | Submission Open
Keywords: translational medicine; biomarkers; high throughput techniques; bioinformatics; in vitro and in vivo models; novel therapies; research applications in pathophysiological backgrounds; molecular/biochemical disease characterization
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Updates on Adrenal Tumors submission deadline 15 Jan 2025 | 3 articles | Viewed by 3843 | Submission Open
Keywords: adrenal; neuroendocrine tumor; biomarkers; pheochromocytoma; urinary steroid profile; plasma steroid profile; chromogranin A; granin family protein
(This special issue belongs to the Section Cell Biology and Pathology)
The Role of NK Cells in Health and Diseases
edited by Matthew Blunt
submission deadline 15 Jan 2025 | 2 articles | Viewed by 2076 | Submission Open
Keywords: NK cells; lymphoma; multiple myeloma; CLL; AML; leukaemia; immunotherapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Angiogenesis, Inflammation, and Oxidative Stress in Inflammatory Bowel Diseases
edited by and Dan Ionuț Gheonea
submission deadline 15 Jan 2025 | 2 articles | Viewed by 1569 | Submission Open
Keywords: inflammatory bowel disease; angiogenesis; inflammation; oxidative stress
(This special issue belongs to the Section Molecular and Translational Medicine)
Mechanisms and Novel Therapeutic Approaches for Arterial and Venous Embolization
edited by Edward W. Lee and Zachary Haber
submission deadline 15 Jan 2025 | Viewed by 313 | Submission Open
Keywords: vascular  embolization; new embolic material; tumoral embolization
(This special issue belongs to the Section Cell Biology and Pathology)
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