Special Issues

Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Innovative Approaches in Drug Discovery
edited by Jitendra Gour
submission deadline 30 Apr 2026 | Viewed by 787 | Submission Open
Keywords: PROTACs; molecular glue; personalized medicine; high-throughput screening (HTS); targeted therapy; drug repurposing; safety profiles
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Emerging Trends in Kidney Disease (2nd Edition)
edited by Andrea Angioi
submission deadline 30 Apr 2026 | 1 articles | Viewed by 725 | Submission Open
Keywords: kidney disease; glomerular diseases; vasculitis; dialysis; hypertension; pediatric nephrology; transplantation; precision medicine; therapeutic advancements
(This special issue belongs to the Section Molecular and Translational Medicine)
Digestive Disorders: Translation and Bridging the Gap Between Research, Diagnosis, and Treatment (2nd Edition)
edited by Goran Poropat and Goran Hauser
submission deadline 30 Apr 2026 | 1 articles | Viewed by 697 | Submission Open
Keywords: acute pancreatitis; clinical nutrition; metabolic disorders; NAFLD; obesity; DGBA; gut microbiota
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Natural and Synthetic Anticancer Agents: Mechanistic Insights and Translational Pathways submission deadline 30 Apr 2026 | 1 articles | Viewed by 684 | Submission Open
Keywords: cancer; drug discovery; synthetic anti-cancer; natural bioactive compounds; nano targeted targeted drug delivery; cancer biomarkers; mechanism of cell death; novel anti-cancer compounds
(This special issue belongs to the Section Cancer Biology and Oncology)
Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes—2nd Edition
edited by
submission deadline 30 Apr 2026 | Viewed by 671 | Submission Open
Keywords: type 2 diabetes; hypertension; LDL-cholesterol; serum lipids; metabolic syndrome; cardiovascular disease; chronic complications; nephropathy
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Isoflavones as Therapeutic Leads: From Natural Sources to Mechanisms and Translational submission deadline 30 Apr 2026 | 1 articles | Viewed by 666 | Submission Open
Keywords: isoflavones; phytoestrogens; natural bioactive compounds; mechanisms of action; translational medicine; therapeutic development; drug discovery
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
The Brain–Body Interplay in Pain, Anesthesia, and Oncology
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 598 | Submission Open
Keywords: brain– body axis; neuroimmune communication; microbiome– gut– brain axis; nociception; anesthetic outcomes; cancer biology
(This special issue belongs to the Section Molecular and Translational Medicine)
Advancements in Understanding and Treating Oral Pathologies: From Dry Mouth to Oral Cancer—2nd Edition
edited by Eleni Georgakopoulou and George Laskaris
submission deadline 30 Apr 2026 | 1 articles | Viewed by 536 | Submission Open
Keywords: oral pathologies; oral diseases; pathogenesis; therapeutic interventions; interdisciplinary nature of oral healthcare; xerostomia; dysgeusia; oral cancer; precancerous lesions; oral inflammatory conditions
(This special issue belongs to the Section Cell Biology and Pathology)
Integrative Roles of Natural Products in Cancer Treatment and Chronic Inflammatory Disease
edited by
submission deadline 30 Apr 2026 | 1 articles | Viewed by 494 | Submission Open
Keywords: natural products; cancer; chronic inflammatory diseases; therapy; oxidative stress
(This special issue belongs to the Section Molecular and Translational Medicine)
Selective Glucocorticoid Receptor Agonists and Modulators (SEGRAMs)
edited by
submission deadline 30 Apr 2026 | Viewed by 424 | Submission Open
Keywords: glucocorticoid receptor; glucocorticoids; transactivation; transrepression; selective glucocorticoid receptor agonists; selective glucocorticoid receptor modulators; inflammation; anti-inflammatory action; side effects; therapeutic potential
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Post Tuberculosis Lung Disease from Lung Damage to the Loss of Lung Function
edited by and Ariadna Petronela Fildan
submission deadline 30 Apr 2026 | Viewed by 393 | Submission Open
Keywords: post-tuberculosis lung disease (PTLD); post-TB conditions; TB sequelae; obstructive post-TB disease; post-TB syndromes
(This special issue belongs to the Section Molecular and Translational Medicine)
Targeted Biologic Therapies for Allergic Conditions: From Bench to Bedside
edited by and Maria Teresa Ventura
submission deadline 30 Apr 2026 | 1 articles | Viewed by 390 | Submission Open
Keywords: biologics; allergic disease; atopic dermatitis; allergic rhinitis; asthma; precision medicine; biomarkers; immunotherapy
(This special issue belongs to the Section Immunology and Immunotherapy)
Bone Diseases: Pathophysiology and Molecular Biology
edited by , and Nicola De Gasperis
submission deadline 30 Apr 2026 | Viewed by 308 | Submission Open
Keywords: bone diseases; osteoporosis; osteoarthritis; Paget’ s disease; bone tumors
(This special issue belongs to the Section Molecular and Translational Medicine)
Bone Metabolism in Health and Disease
edited by
submission deadline 30 Apr 2026 | Viewed by 282 | Submission Open
Keywords: bone remodeling; skeletal stem cells; osteocyte; osteoblasts; osteoclasts; osteoporosis; osteoarthritis; bone regeneration; bone aging; bone therapeutics
(This special issue belongs to the Section Molecular and Translational Medicine)
Oxidative Stress, Inflammation and Endothelial Dysfunction in COVID-19 Era and Long COVID-19 Complications submission deadline 30 Apr 2026 | Viewed by 272 | Submission Open
Keywords: oxidative stress; redox-disbalance; COVID-19; post-COVID-19; cytokines; mitochondrial dysfunction; endothelial damages; ROS and RNS; thrombosis; antioxidant therapy; oxidative shock
(This special issue belongs to the Section Molecular and Translational Medicine)
Molecular and Cellular Mechanisms of Cardiovascular Diseases: 2nd Edition
edited by
submission deadline 30 Apr 2026 | Viewed by 266 | Submission Open
Keywords: hypertension; diabetes; coronary heart disease; valvular heart disease; infective endocarditis; aortic dissection; aortic aneurysm; heart failure; cardiomyopathy
(This special issue belongs to the Section Molecular and Translational Medicine)
New Advances in Oral Pathology and Medicine
edited by
submission deadline 30 Apr 2026 | Viewed by 249 | Submission Open
Keywords: molecular diagnostics; imaging technologies; artificial intelligence; targeted therapies; regenerative medicine
(This special issue belongs to the Section Molecular and Translational Medicine)
Nanoparticle-Labeled Exosomes as Theranostic Agents
edited by Karrer M. Alghazali
submission deadline 30 Apr 2026 | Viewed by 247 | Submission Open
Keywords: exosomes; nanotheranostic agent; nanoparticles; exosome labeling; photothermal therapy; drug delivery vehicle; imaging probe
(This special issue belongs to the Section Cell Biology and Pathology)
Selected Papers from the Tanawwo Workshop on Clinical Research in Precision Medicine, Rare Diseases, and Pharmacogenomics (Doha, Qatar, 2025)
edited by and Radja Messai Badji
submission deadline 30 Apr 2026 | Viewed by 223 | Submission Open
Keywords: precision medicine; rare diseases; pharmacogenomics; adaptive and platform trials; multi-omics integration; artificial intelligence in clinical research; big data and digital health; translational medicine
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Mechanisms and Novel Therapeutic Approaches for Gliomas: 2nd Edition
edited by Maria V. Chatziathanasiadou
submission deadline 30 Apr 2026 | Viewed by 211 | Submission Open
Keywords: glioma; molecular mechanisms; tumour immunity; tumour metabolism; tumour microenvironment; metabolic therapies; immunotherapies; combination treatment
(This special issue belongs to the Section Cancer Biology and Oncology)
Correlative Light and Electron Microscopy (CLEM) in Biomedicine: Advances and Applications
edited by
submission deadline 30 Apr 2026 | Viewed by 182 | Submission Open
Keywords: CLEM; correlative microscopy; biomedicine; pathology; virology; oncology; immunolabeling; cryo-microscopy; ultrastructure; image analysis
(This special issue belongs to the Section Cell Biology and Pathology)
Cancer Genetics: Bench-to-Bedside​ Advances
edited by
submission deadline 30 Apr 2026 | Viewed by 176 | Submission Open
Keywords: cancer genetics; somatic mutations; biomarkers; cfDNA/ctDNA; epigenetics; tumor microenvironment; multi-omics; precision medicine
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Advances in Ocular Surface Disease
edited by
submission deadline 30 Apr 2026 | Viewed by 163 | Submission Open
Keywords: dry eye disease; corneal neuroimmune interactions; meibomian gland dysfunction; microbial keratitis; ocular allergy; corneal degeneration
(This special issue belongs to the Section Molecular and Translational Medicine)
State-of-the-Art Drug Discovery and Development in Poland (3rd Edition) submission deadline 30 Apr 2026 | Viewed by 163 | Submission Open
Keywords: in silico drug target profiling; drug delivery systems; drug– drug interaction; target-based screening; phenotypic screening; pharmaceutical modeling; computational chemistry; targeted therapy; biomarkers; bioimaging
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Nanoparticles in Biomedical Engineering: From Drug Delivery to Tissue Engineering
edited by Jia Nong
submission deadline 30 Apr 2026 | Viewed by 152 | Submission Open
Keywords: nanoparticle; nanomedicine; nanoconjugates; drug delivery; biomaterials; wound healing; angiogenesis; antimicrobial agents; regenerative medicine; theranostics
(This special issue belongs to the Section Nanomedicine and Nanobiology)
Animal Models in Pulmonary Research: Shaping the Future of Translational Respiratory Medicine submission deadline 30 Apr 2026 | Viewed by 140 | Submission Open
Keywords: pulmonary disease; lung regeneration and repair; animal models; genetically modified models; lung injury induction; translational research
(This special issue belongs to the Section Molecular and Translational Medicine)
Recent Advances in Cancer Metastasis Models
edited by
submission deadline 30 Apr 2026 | Viewed by 130 | Submission Open
Keywords: cancer metastasis; tumor microenvironment; metastasis models; 3D cell culture; organoids; artificial intelligence in oncology; machine learning; bioinformatics; in vivo imaging; multi-omics integration
(This special issue belongs to the Section Cancer Biology and Oncology)
Recent Advances in Research on Neuroendocrine Neoplasms and Endocrine Sequelae After Oncological Disease
edited by Hermann L. Müller
submission deadline 30 Apr 2026 | Viewed by 130 | Submission Open
Keywords: neuroendocrine tumors; endocrinology; hormones; cancer; sequelae; late effects; neurogenic tumors
(This special issue belongs to the Section Cancer Biology and Oncology)
Artificial Intelligence in Cancer Imaging: Advancing Precision Oncology
edited by Farhan Akram
submission deadline 30 Apr 2026 | Viewed by 130 | Submission Open
Keywords: artificial intelligence; cancer imaging; digital pathology; machine learning; deep learning; radiomics; tumor characterization; precision oncology; biomarker discovery; clinical translation
(This special issue belongs to the Section Cancer Biology and Oncology)
Advances in Chronic Obstructive Pulmonary Disease (COPD)
edited by Fabio Manzo and
submission deadline 30 Apr 2026 | Viewed by 129 | Submission Open
Keywords: chronic obstructive pulmonary disease; COPD; emphysema; chronic bronchitis; chronic disease; disability; rehabilitation
(This special issue belongs to the Section Cell Biology and Pathology)
Extracellular Vesicles: A New Frontier in Liquid Biopsy
edited by Chen Zhao and You-Ren Ji
submission deadline 30 Apr 2026 | Viewed by 127 | Submission Open
Keywords: extracellular vesicles (EVs); liquid biopsy; circulating biomarkers; exosome; nanomedicine; translational oncology; precision medicine
(This special issue belongs to the Section Cell Biology and Pathology)
Roles of Extracellular Vesicles in Health and Diseases
edited by David R. Brigstock and Xinlei Li
submission deadline 30 Apr 2026 | Viewed by 126 | Submission Open
Keywords: extracellular vesicle; exosome; pathogenesis; therapy; cancer; neurodegenerative diseases; pulmonary diseases; cardiovascular diseases; inflammatory diseases; infectious diseases; kidney diseases; gastrointestinal diseases; aging; diabetes; autoimmune disorders
(This special issue belongs to the Section Molecular and Translational Medicine)
Advances in Research on Spermatozoa and Male Infertility: From Molecular Mechanism to Therapeutic Perspectives submission deadline 30 Apr 2026 | Viewed by 124 | Submission Open
Keywords: spermatozoa biology; molecular mechanisms of spermatogenesis; oxidative stress and sperm function; therapeutic strategies for addressing male infertility
(This special issue belongs to the Section Molecular and Translational Medicine)
Decoding Aging with AI and Computational Modeling
edited by Bingrui Li, Xuanye Cao and Wen Jiang
submission deadline 30 Apr 2026 | Viewed by 124 | Submission Open
Keywords: aging; computational modeling; AI; healthspan and lifespan prediction; systems biology
(This special issue belongs to the Section Cell Biology and Pathology)
Alzheimer's Disease: Pathogenesis, Diagnostics and Novel Treatment Options
edited by and Ling Li
submission deadline 30 Apr 2026 | Viewed by 122 | Submission Open
Keywords: amyloid and tau pathology; neuroinflammation and oxidative stress; neuromodulation; fluid biomarkers; imaging and other diagnostic approaches; small-molecule therapeutics; novel therapeutics and emerging therapies; disease-modifying therapies; experimental and clinical pharmacology
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Cardiometabolic Diseases: Molecular Biomarkers and Treatment Strategies submission deadline 30 Apr 2026 | Viewed by 120 | Submission Open
Keywords: cardiometabolic disease; obesity; diabetes mellitus; insulin resistance; lipid status; biomarkers; hypertension; metabolic dysregulation; personalized therapy; omics technologies
(This special issue belongs to the Section Endocrinology and Metabolism Research)
Brain Tumor: From Pathophysiology to Novel Therapies
edited by
submission deadline 30 Apr 2026 | Viewed by 119 | Submission Open
Keywords: glioblastoma; immunotherapy; molecular subtype; radiotherapy; molecular therapy; emerging treatment; drug resistance; MRI; immune surveillance  
(This special issue belongs to the Section Cancer Biology and Oncology)
Genome Engineering Technologies for Diseases
edited by Kosuke Ishikawa
submission deadline 30 Apr 2026 | Viewed by 118 | Submission Open
Keywords: genome engineering; gene editing; gene delivery; transposable elements; insertinal mutagenesis; functional genomics; in silico analysis; cell-based assays; disease modeling; cell therapy
(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)
Gynecological Cancers: Progress and Challenges
edited by
submission deadline 30 Apr 2026 | Viewed by 115 | Submission Open
Keywords: gynecological cancer; therapeutic targets; precision medicine; immunotherapy; drug resistance; biomarkers; molecular mechanisms; natural compound; translational research; adjuvant therapy
(This special issue belongs to the Section Cancer Biology and Oncology)
Personalized Diagnosis and Therapy in Endocrinology and Gynecology
edited by
submission deadline 30 Apr 2026 | Viewed by 115 | Submission Open
Keywords: personalized medicine; endocrine disorders; gynecological diseases; reproductive endocrinology; pharmacogenomics; hormonal therapy; polycystic ovary syndrome (PCOS); precision medicine; biomarkers; women’ s health
(This special issue belongs to the Section Molecular and Translational Medicine)
Biomaterials and Nanotechnology for Advanced Wound Dressings
edited by Javad Esmaeili
submission deadline 30 Apr 2026 | Viewed by 113 | Submission Open
Keywords: wound dressings; wound healing; biomaterials and nanotechnology; regenerative medicine; targeted delivery
(This special issue belongs to the Section Nanomedicine and Nanobiology)
New Insights into the Tumor Microenvironment: Mechanisms and Therapeutic Strategies
edited by
submission deadline 30 Apr 2026 | Viewed by 112 | Submission Open
Keywords: tumor microenvironment (TME); immune evasion; tumor– immune interaction; stromal remodeling; cancer immunotherapy; metabolic reprogramming; epigenetic regulation; multi-omics and spatial analysis; anticancer drug development
(This special issue belongs to the Section Immunology and Immunotherapy)
Nanocarriers in Mucosal Drug Delivery
edited by
submission deadline 30 Apr 2026 | Viewed by 109 | Submission Open
Keywords: nanocarriers; mucosal drug delivery; mucoadhesion; mucus penetration; controlled release; bioavailability enhancement; targeted delivery; stimuli-responsive systems
(This special issue belongs to the Section Drug Discovery, Development and Delivery)
Epilepsy: From Mechanisms to Therapeutic Approaches (2nd Edition)
edited by
submission deadline 30 Apr 2026 | Viewed by 107 | Submission Open
Keywords: genetic epilepsy; acquired epilepsy; neonatal seizures; epileptogenesis; pharmacoresistant epilepsy; ion channels; calcium signaling
(This special issue belongs to the Section Molecular and Translational Medicine)
Neuropathology: Understanding Local and Systemic Influence of Disease and Vice-Versa
edited by , , Meenakshi Ahluwalia, and Shashi Nandar Kumar
submission deadline 30 Apr 2026 | Viewed by 107 | Submission Open
Keywords: brain pathologies; brain injury; Parkinson’ s disease; Alzheimer’ s disease; stroke; neurodegeneration; hemorrhages; hypoxia; neuroinflammation; translational approaches; oxidative stress; COVID-19; gut– brain axis; systemic influence; immune interaction; synaptic plasticity; ageing; senescence; bone marrow and neuropathology; pesticides; preservatives and environmental contamination; lungs and brain; liver and brain; cardiovascular effect of brain pathology and vice-versa; acute and chronic neuro-immune interaction; therapeutic strategies and intervention; alternative medicines in brain pathologies
(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)
Biomarker, Phenotyping and Therapeutics for Asthma
edited by
submission deadline 30 Apr 2026 | Viewed by 101 | Submission Open
Keywords: allergy; biomarkers; pathogenesis; exhaled breath; multi-omics; lung physiology; phenotyping; endotypes; therapeutic targets
(This special issue belongs to the Section Molecular and Translational Medicine)
Autophagy-Mediated Signalling in Cancer Metastasis and Progression submission deadline 30 Apr 2026 | Viewed by 99 | Submission Open
Keywords: autophagy; cancer; resistance; metastasis; tumor microenvironment; immune evasion
(This special issue belongs to the Section Cancer Biology and Oncology)
Photodynamic Therapy in Cancer—Second Edition
edited by
submission deadline 30 Apr 2026 | Viewed by 97 | Submission Open
Keywords: photodynamic therapy; targeted drug delivery and drug release systems; photodiagnosis/tumor imaging; PDT-induced immunogenic cell death; nanomaterials-based combination therapies; theranostics
(This special issue belongs to the Section Cancer Biology and Oncology)
Rheumatic Diseases: From Pathophysiology to Current and Emerging Therapeutic Approaches
edited by Harriet Morf
submission deadline 30 Apr 2026 | Viewed by 96 | Submission Open
Keywords: rheumatic diseases; molecular mechanisms; treatment; artificial intelligence; cytokine; anti-rheumatic drugs
(This special issue belongs to the Section Immunology and Immunotherapy)
Role of Oxidative Stress, Antioxidants, and Gut Microbiota in Obesity and Metabolic Disorders
edited by Lunawati Bennett
submission deadline 30 Apr 2026 | Viewed by 96 | Submission Open
Keywords: obesity; metabolic diseases; antioxidants; gut microbiota; inflammation; reactive oxygen species; cardiovascular diseases
(This special issue belongs to the Section Endocrinology and Metabolism Research)
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