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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Feature Reviews in Imaging Technology for Human Diseases

edited by

Giulio Distefano

and

Antonio Granata

submission deadline 31 Dec 2025 | Viewed by 174 | Submission Open

Keywords: medical imaging; advanced radiological techniques; artificial intelligence; molecular imaging; computed tomography (CT); magnetic resonance imaging (MRI); ultrasound; fluoroscopy; optical imaging; liquid biopsy

(This special issue belongs to the Section Biomedical Engineering and Materials)

Animal Models for the Study of Cardiovascular Physiology—Second Edition

edited by Sandra Lia Amaral

submission deadline 31 Dec 2025 | Viewed by 172 | Submission Open

Keywords: hypertension; stroke; myocardium infarction; arterial stiffness; supravalvular aortic stenosis; cardiac remodeling; capillary angiogenesis; exercise training; vascular diseases; non-pharmacological treatment

(This special issue belongs to the Section Cell Biology and Pathology)

Omics Approaches on Immune-Mediated Inflammatory Diseases: Towards Novel Biomarkers and Potential Therapeutic Targets, 3rd Edition

edited by

Maria-Ioanna Christodoulou

submission deadline 31 Dec 2025 | Viewed by 164 | Submission Open

Keywords: IMIDs; IBD; Crohn’ s disease; ulcerative colitis; SLE; Sjogren’ s syndrome; rheumatoid arthritis; psoriatic arthritis; multiple sclerosis; bulk and single-cell omics; multi-omics flow cytometry; next-generation microscopy; tissue microarrays; systems biology

(This special issue belongs to the Section Immunology and Immunotherapy)

Advances in Heart–Brain Axis

edited by Teresa Soda

submission deadline 31 Dec 2025 | Viewed by 161 | Submission Open

Keywords: heart– brain axis; neurocardiology; autonomic nervous system; neuroinflammation; cardiac– cerebral syndromes; psychocardiology; calcium signaling; synaptic plasticity; ion transport; translational neuroscience

(This special issue belongs to the Section Molecular and Translational Medicine)

New Insights in Reproductive Health and Disease

edited by

Chi Chiu Wang

submission deadline 31 Dec 2025 | Viewed by 151 | Submission Open

Keywords: reproductive health; artificial intelligence; fertility preservation; stem cells; gene therapy; materials; meiosis; DNA double-strand break; ovarian dysfunction; nanomedicine; pregnancy complications

(This special issue belongs to the Section Molecular and Translational Medicine)

Nanobiomaterials with Antimicrobial and Anticancer Applications: Second Edition

edited by

Rajni Verma

and

Saurabh Pathak

submission deadline 31 Dec 2025 | Viewed by 146 | Submission Open

Keywords: nanobiomaterials; nanomaterials biomaterials; anti-bacterial; anti-cancer

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Advancements and Innovations in Chemotherapy

edited by

Yu-Jung Lin

submission deadline 31 Dec 2025 | Viewed by 112 | Submission Open

Keywords: chemotherapy; drug resistance; immunotherapy; combination therapy; drug delivery systems; novel agents; personalized medicine; tumor microenvironment

(This special issue belongs to the Section Cell Biology and Pathology)

Gene- and Peptide-Based Therapeutics for Neurodegenerative Disorders

edited by

Ramona Meanti

and Chiara Lucchi

submission deadline 31 Dec 2025 | Viewed by 111 | Submission Open

Keywords: neurodegenerative diseases; gene therapy; peptide-based therapeutics; targeted drug delivery; neuroprotection

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Oral Squamous Cell Carcinoma: Molecular Signaling Pathways and Novel Biomarkers—2nd Edition

edited by

Sadhna Aggarwal

submission deadline 31 Dec 2025 | Viewed by 110 | Submission Open

Keywords: oral squamous cell carcinoma (OSCC); molecular signaling pathways; biomarkers; pathogenesis; targeted therap; tumor growth; tumor invasion; angiogenesis; tumor metastasis; immune response modulation

(This special issue belongs to the Section Cancer Biology and Oncology)

Three-Dimensional Printed Meshes in Guided Bone Regeneration

edited by

Giulia Guarnieri

Annamaria Morelli

and

Claudio Cirrincione

submission deadline 31 Dec 2025 | Viewed by 109 | Submission Open

Keywords: 3D– 4D printing; vascular metabolism; mucosal stiffness; bone and gingival cells metabolism; bioprinting; melt electrowriting; shape-memory materials; titanium and polycaprolactone meshes

(This special issue belongs to the Section Biomedical Engineering and Materials)

Pharmacogenomics and Drug Metabolism: From Cytochrome P450 to Emerging Enzymatic Pathways

edited by

Pradeepraj Durairaj

submission deadline 31 Dec 2025 | Viewed by 107 | Submission Open

Keywords: cytochrome P450 (CYP450); drug metabolism; xenobiotic metabolism; pharmacogenomics; biotransformation; orphan enzymes; redox biology; enzyme engineering; multi-omics approaches; personalized medicine

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

HIV Therapy: The Latest Developments in Antiviral Drugs

edited by

Francisco Javier Fanjul Losa

submission deadline 31 Dec 2025 | Viewed by 103 | Submission Open

Keywords: HIV; antiviral drugs; experimental therapeutics; drug discovery; viral reservoirs; mechanism of action; preclinical models; novel HIV targets; antiretroviral therapy (ART); immunotherapy (experimental aspects)

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Molecular Biology of Cancer: From Biomarkers to Targeted Therapy

edited by

Georgia Levidou

submission deadline 31 Dec 2025 | Viewed by 94 | Submission Open

Keywords: molecular biology; carcinogenesis; cancer; biomarkers; prognostic markers; predictive markers; precision medicine; targeted therapy

(This special issue belongs to the Section Cell Biology and Pathology)

Dopamine and Androgen Receptor Signaling: Novel Insights in Cancer Biology

edited by Srijan Acharya

submission deadline 31 Dec 2025 | Viewed by 90 | Submission Open

Keywords: dopamine signaling; androgen receptor; cancer biology; hormone-sensitive tumors; signal transduction; tumor microenvironment; neurotransmitters in cancer; prostate cancer; breast cancer; targeted therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

MicroRNAs in Precision Medicine: Regulation, Biomarkers and Novel Therapeutics

edited by Shing Cheng Tan

submission deadline 31 Dec 2025 | Viewed by 88 | Submission Open

Keywords: MicroRNAs; non-coding RNAs; biomarkers; therapeutic targets; cancer; omics technologies; precision medicine; disease pathogenesis

(This special issue belongs to the Section Molecular and Translational Medicine)

Pathogenesis and Novel Diagnostic Techniques in Juvenile Idiopathic Arthritis—Second Edition

edited by

Katarzyna Winsz-Szczotka

submission deadline 31 Dec 2025 | Viewed by 85 | Submission Open

Keywords: juvenile idiopathic arthritis; pathogenesis; cartilage and bone anabolism and catabolism; diagnostics; treatment; prevention

(This special issue belongs to the Section Molecular and Translational Medicine)

Epigenetics in Human Cancer: Emerging Biomarkers and Therapeutic Targets

edited by

Jeong-yeon Lee

submission deadline 31 Dec 2025 | Viewed by 83 | Submission Open

Keywords: cancer; epigenetics; DNA methylation; histone modification; chromatin remodeling; non-coding RNAs; therapeutic resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Pathogenesis and Therapeutic Intervention of Alzheimer's Disease

edited by Chanchal Sharma

submission deadline 31 Dec 2025 | Viewed by 72 | Submission Open

Keywords: dementia; Alzheimer’ s disease; neuroinflammation; microglia; gene therapy; stem cells; blood– brain barrier; oxidative stress; gut-microbiome; diet; artificial intelligence

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Genetic Research on Colorectal Cancers

edited by

Wangxiong Hu

submission deadline 31 Dec 2025 | Viewed by 67 | Submission Open

Keywords: high microsatellite instability; epigenetic age acceleration; spatial omics and single-cell sequencing; cold tumors and immunotherapy; driver gene; DNA replication repair; liquid biopsy; ctDNA

(This special issue belongs to the Section Cancer Biology and Oncology)

Advances in Pathogenesis and Treatment of Infectious Diseases

edited by Francesca Gioia

submission deadline 31 Dec 2025 | Viewed by 65 | Submission Open

Keywords: antimicrobial resistance; phage therapy; host– pathogen interactions; molecular diagnostics; immunotherapy

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Pathomechanisms of Disturbances Underlying Chronic Disorders—Third Edition

edited by

Dorota Formanowicz

submission deadline 31 Dec 2025 | Viewed by 62 | Submission Open

Keywords: chronic disorders; atherosclerosis; inflammation; oxidative stress; lipoproteins; endothelial dysfunction; biomarkers; pathomechanisms

(This special issue belongs to the Section Immunology and Immunotherapy)

Vitamin D in Health and Disease (4th Edition)

edited by

Giuseppe Murdaca

submission deadline 31 Dec 2025 | Viewed by 62 | Submission Open

Keywords: vitamin D and the immune system; vitamin D and cytokines; vitamin D and microbiome; vitamin D and respiratory diseases; vitamin D and autoimmune diseases; vitamin D and allergies

(This special issue belongs to the Section Molecular and Translational Medicine)

Signaling of Protein Kinases in Development and Disease (2nd Edition)

edited by

John Zheng Fu

submission deadline 31 Dec 2025 | Viewed by 59 | Submission Open

Keywords: kinase; phosphorylation; signaling; mutation; mechanism; development; inhibitor; disease

(This special issue belongs to the Section Cell Biology and Pathology)

Advances in Chondrocyte Biology (2nd Edition)

edited by

Bo Qiu

submission deadline 31 Dec 2025 | Viewed by 58 | Submission Open

Keywords: osteoarthritis; chondrocyte; differentiation; proliferation; signaling pathways; transcription factor; inflammation; cellular processes; cartilage repair

(This special issue belongs to the Section Cell Biology and Pathology)

Novel Drug Delivery Systems: Design, Evaluation and Application: 2nd Edition

edited by

Yongtai Zhang

submission deadline 31 Dec 2025 | Viewed by 58 | Submission Open

Keywords: pharmaceutics; drug delivery systems; nanoparticles; nanomedicine; biomolecules; hydrogels; biomaterials

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Inflammation in Neurogenerative Diseases: Mechanisms and Therapeutic Frontiers

edited by

Shao-Bin Wang

submission deadline 1 Jan 2026 | Viewed by 78 | Submission Open

Keywords: neuroinflammation; neurodegenerative diseases; biomarkers mitochondria dysfunction; microglia; immune response; therapeutic development; gene therapy

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nanoparticles for Glioblastoma Therapy

edited by Shambhavi Pandey and

Benjamí Oller-Salvia

submission deadline 20 Jan 2026 | Viewed by 58 | Submission Open

Keywords: nanoparticles; blood& ndash; brain barrier; gene delivery; glioblastoma; cancer stem cells; biomaterials

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Prostate Cancer: From Pathology to Novel Therapeutic Approaches (2nd Edition)

edited by

Gvantsa Kharaishvili

submission deadline 30 Jan 2026 | 1 articles | Viewed by 2089 | Submission Open

Keywords: prostate cancer; castration-resistant prostate cancer; metastatic disease; biomarker; tumor microenvironment; treatment; immunotherapy; drug resistance

(This special issue belongs to the Section Cancer Biology and Oncology)

Feature Reviews in Cytokines

edited by

Monika Zajkowska

submission deadline 30 Jan 2026 | 2 articles | Viewed by 1297 | Submission Open

Keywords: cytokines; neurodegenerative disease; cancer; diabetes; obesity; immunological disorder; cardiovascular disease; diagnosis; biomarker; treatment

(This special issue belongs to the Section Molecular and Translational Medicine)

Mechanisms of Cell Death in Cancer Cells: A New Therapeutic Opportunity—2nd Edition

edited by

Adrian-Bogdan Țigu

submission deadline 31 Jan 2026 | 6 articles | Viewed by 14936 | Submission Open

Keywords: cell death; drug repositioning; translational research; oncology; cancer therapy; apoptosis

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Biomarkers in Inflammatory Bowel Disease: Pathophysiology and New Therapeutic Strategies—Second Edition

edited by

Marino Vilović

submission deadline 31 Jan 2026 | 5 articles | Viewed by 11664 | Submission Open

Keywords: inflammatory bowel disease (IBD); Crohn’ s disease; ulcerative colitis; biomarkers; molecular biomarkers in IBD; pathophysiology; therapeutic approaches in IBD; precision medicine

(This special issue belongs to the Section Cell Biology and Pathology)

Cardiovascular and Metabolic Disease: New Treatment and Future Directions—4th Edition

edited by

Alfredo Caturano

submission deadline 31 Jan 2026 | 10 articles | Viewed by 10895 | Submission Open

Keywords: cardiovascular disease; metabolic disease; diabetes; therapy; drugs; implantable device; heart failure; heart transplantation; cardiac surgery; future directions

(This special issue belongs to the Section Cell Biology and Pathology)

Molecular Research of Neurodegenerative and Psychiatric Diseases, 2nd Edition

edited by

Dubravka Švob Štrac

submission deadline 31 Jan 2026 | 6 articles | Viewed by 10115 | Submission Open

Keywords: neurodegenerative disorders; psychiatric diseases; biomarkers; therapeutic targets; omics approaches; molecular pathways; cell biology; animal models; clinical studies

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Molecular Mechanisms and Novel Therapies for Brain Injury: 2nd Edition

edited by

Arjun Sapkota

submission deadline 31 Jan 2026 | 4 articles | Viewed by 7897 | Submission Open

Keywords: stroke; spinal cord injury; traumatic brain injury; seizure; brain tumors; neurodegeneration; neuroinflammation; blood– brain barrier disruption; neuroprotection; drug discover; mechanism of action; target validation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Nanoparticle-Based Drug Delivery in Cancer Therapy: Current Progress and Challenges

edited by

Menghuan Tang

and

Zhaoqing Cong

submission deadline 31 Jan 2026 | 3 articles | Viewed by 7083 | Submission Open

Keywords: nanoparticle; targeted drug delivery; controlled release; clinical translation; drug resistance; nanomedicine

(This special issue belongs to the Section Nanomedicine and Nanobiology)

Therapeutic Potential for Cannabis and Cannabinoids, 3rd Edition

edited by

Wesley M. Raup-Konsavage

submission deadline 31 Jan 2026 | 2 articles | Viewed by 6188 | Submission Open

Keywords: cannabis; tetrahydrocannabinols (THC); cannabidiol (CBD); cannabigerol (CBG); cannabinoid; cannabinol (CBN); cannabichromene (CBC); pain; cancer; anxiety; PTSD; sleep disorders; neuroprotection; anti-inflammatory

(This special issue belongs to the Section Molecular and Translational Medicine)

Hypertension and Chronic Renal Failure

edited by

Caterina Carollo

submission deadline 31 Jan 2026 | 4 articles | Viewed by 6072 | Submission Open

Keywords: hypertension; chronic renal failure; NephroCardiology

(This special issue belongs to the Section Molecular and Translational Medicine)

Triple Negative Breast Cancer: From Mechanisms to Therapeutic Approaches

edited by Emad Rakha and Padmashree Rida

submission deadline 31 Jan 2026 | 5 articles | Viewed by 5842 | Submission Open

Keywords: triple-negative breast cancer; neoadjuvant; adjuvant; chemotherapy; immunotherapy; antibody– drug conjugates; immune checkpoint inhibitors; DNA damage; EGFR; FGFR; microtubule dynamics; centrosome amplification

(This special issue belongs to the Section Cancer Biology and Oncology)

Applications and Perspectives of Cold Electric Discharge Plasmas in Biomedicine and Bioengineering

edited by

Andrei Vasile Nastuta

submission deadline 31 Jan 2026 | 5 articles | Viewed by 5715 | Submission Open

Keywords: plasma medicine; plasma pharmacology; plasma oncology; plasma bioengineering; plasma agronomy

(This special issue belongs to the Section Molecular and Translational Medicine)

Medicinal Chemistry in Drug Design and Discovery, 2nd Edition

edited by

Małgorzata Jarończyk

submission deadline 31 Jan 2026 | 2 articles | Viewed by 4316 | Submission Open

Keywords: design and synthesis of medicinal compounds; identification and characteristics of targets; mechanism of action; profiles of safety; structure– activity relationship; ligand– target interactions; drugs repurposing

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Nervous System Diseases: From Pathophysiology to Novel Therapeutic Approaches

edited by Natalia Rozas and Cameron Jeter

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3739 | Submission Open

Keywords: neurodegenerative diseases; neuromuscular diseases; autoimmune diseases of the nervous system; brain diseases; neuroinflammatory diseases; neuromuscular diseases; trauma of the nervous system

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

PPARs in Health and Disease, 2nd Edition

edited by

Maria Konstandi

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3597 | Submission Open

Keywords: PPARα ; PPARβ /δ ; PPARγ ; nuclear receptor; lipid homeostasis; glucose homeostasis; neurodegenerative disorders; dyslipidemia; atherosclerosis; cardiovascular disease; cancer

(This special issue belongs to the Section Cell Biology and Pathology)

Feature Reviews in Infection and Immunity

edited by

Vijay Singh Gondil

submission deadline 31 Jan 2026 | 1 articles | Viewed by 3212 | Submission Open

Keywords: emerging pathogens; antimicrobial resistance; vaccine; host-pathogen immune interactions; immunotherapy; antimicrobial drug; immune evasion; innate and adaptive immunity

(This special issue belongs to the Section Immunology and Immunotherapy)

State-of-the-Art Neonatal Medicine in Japan

edited by

Fumihiko Namba

submission deadline 31 Jan 2026 | 3 articles | Viewed by 3176 | Submission Open

Keywords: mesenchymal stromal cells; artificial placenta; therapeutic gasses; animal models; off-label drug use

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Combination Therapy for Chronic Diseases: Bridging Conventional and Natural Products for Enhanced Outcomes

edited by

Xian (Phoebe) Zhou

submission deadline 31 Jan 2026 | 2 articles | Viewed by 3108 | Submission Open

Keywords: combination therapy; interaction; chronic diseases; synergy; molecular pathways; mathematical methods; minimizing side effects

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Biomarkers and More Efficient Therapies for Sepsis—2nd Edition

edited by

Wen-Lin Su

, Chih-Hao Shen,

Sheng-Kang Chiu

and

Yi-Ting Chen

submission deadline 31 Jan 2026 | 3 articles | Viewed by 2961 | Submission Open

Keywords: sepsis; organ dysfunction; inflammatory process; molecular biomarkers; pathogen infection; signal transduction mechanisms

(This special issue belongs to the Section Molecular and Translational Medicine)

Parkinson’s Disease: Where Are We and Where Are We Going To

edited by Carmen Borrué

submission deadline 31 Jan 2026 | 1 articles | Viewed by 2885 | Submission Open

Keywords: Parkinson’ s disease; gait disorders; biomarkers; neurodegenerative disease; AI

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Ophthalmic Genetics: Unraveling the Genomics of Eye Disorders

edited by Raffaella Cascella

submission deadline 31 Jan 2026 | 4 articles | Viewed by 2860 | Submission Open

Keywords: ophthalmic genetics; inherited retinal disease; genomics; molecular biology; gene therapy; artificial intelligence; bioinformatics; biostatistical analysis

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

New Advances in Human Reproductive Biology

edited by

Nikolaos Machairiotis

submission deadline 31 Jan 2026 | 3 articles | Viewed by 2788 | Submission Open

Keywords: gametogenesis; fertilization; egg retrieval; embryo implantation; epigenetics; microRNAs in fertility; hormonal signaling; stem cells and fertility; assisted reproductive technologies; molecular and polymorphism in fertility; reproductive health novelty

(This special issue belongs to the Section Molecular and Translational Medicine)

Infectious Diseases: Prevention, Diagnosis, and Treatment Under Antimicrobial Resistance Global Urgency

edited by

Célia F. Rodrigues

submission deadline 31 Jan 2026 | 3 articles | Viewed by 2785 | Submission Open

Keywords: AMR; infectious diseases; bacteria; fungi; alternative treatment

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Displaying special issue 351-400 on page 8 of 16.

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