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Biomedicines publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Mitochondrial Dysfunction and Reactive Oxygen Species in Aging and Related Diseases

edited by

Pankaj Patyal

and Gohar Azhar

submission deadline 28 Feb 2025 | Viewed by 84 | Submission Open

Keywords: mitochondrial dysfunction; aging; reactive oxygen species; mitochondrial dynamics; mitophagy; mitochondrial biogenesis; age-related disorders

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Feature Reviews in Biomaterials for Oral Diseases

edited by

Oliver Schierz

submission deadline 28 Feb 2025 | Viewed by 83 | Submission Open

Keywords: dental composites; ceramics; zirconia; polymers; polyaryletherketone; polyoxymethylene; titanium; bone graft materials; implants

(This special issue belongs to the Section Biomedical Engineering and Materials)

The Role of Immune Response in the Protection against SARS-CoV-2 Infection

edited by

Cinzia Giagulli

submission deadline 28 Feb 2025 | Viewed by 83 | Submission Open

Keywords: SARS-CoV-2; COVID-19; immune response; innate immune system; adaptative response; vaccines

(This special issue belongs to the Section Immunology and Immunotherapy)

Organoid, Organ-on-Chip and Advanced 2D/3D Models for Human Tissue Engineering Applications

edited by

Ahmad Salti

submission deadline 28 Feb 2025 | Viewed by 78 | Submission Open

Keywords: organoid; organ-on-chip; 2D/3D model; tissue engineering; induced pluripotent stem cells; in vitro model

(This special issue belongs to the Section Biomedical Engineering and Materials)

Advances in Cardiovascular Remodeling: Molecular Mechanisms and Therapeutic Targets

edited by

Elena Kaschina

submission deadline 28 Feb 2025 | Viewed by 76 | Submission Open

Keywords: cardiac remodeling; vascular remodeling; ageing; pathogenesis; molecular mechanisms; diagnostics; therapy

(This special issue belongs to the Section Molecular and Translational Medicine)

Unraveling the Epigenetic Blueprint: Exploring DNA Methylation and Its Integration with Omics in Health and Disease

edited by Priyadarshini Kachroo and Rinku Sharma

submission deadline 28 Feb 2025 | Viewed by 68 | Submission Open

Keywords: multiomics; networks; epigenomics; machine learning; causation; early-life exposures; aging; translational therapeutics; metabolomics; epigenomics; exposomics; proteomics; microbiome

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Innovative Approaches in Drug Discovery

edited by Jitendra Gour

submission deadline 28 Feb 2025 | Viewed by 67 | Submission Open

Keywords: PROTACs; molecular glue; personalized medicine; high-throughput screening (HTS); targeted therapy; drug repurposing; safety profiles

(This special issue belongs to the Section Drug Discovery and Development)

Advances in Fetal Medicine and Neonatology

edited by

Robert Brawura-Biskupski-Samaha

submission deadline 28 Feb 2025 | Viewed by 61 | Submission Open

Keywords: fetal medicine; neonatology; research innovations; perinatal care; clinical practices

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular Regulation of Spermatozoa—Second Edition

edited by

Atefeh Najafi

submission deadline 28 Feb 2025 | Viewed by 60 | Submission Open

Keywords: spermatogenesis; spermiogenesis; sperm; capacitation; acrosome reaction; hyperactivation; fertilization; male infertility; antioxidants; redox regulation

(This special issue belongs to the Section Cell Biology and Pathology)

Feature Reviews in Precision Oncology

edited by

Luca Filippi

submission deadline 28 Feb 2025 | Viewed by 59 | Submission Open

Keywords: cancer treatment; genomic and molecular profiling; targeted therapies and immunotherapies; molecular imaging and theranostics; biomarker discovery and validation; personalized treatment strategies

(This special issue belongs to the Section Cancer Biology and Oncology)

Immunogenetic Regulations for Disease Prognosis

edited by Anshuman Mishra and

Trim Lajqi

submission deadline 28 Feb 2025 | Viewed by 59 | Submission Open

Keywords: immunity; host susceptibility; gene expression; biotechnology; disease resistance; immunogenicity; drug monitoring; vaccines; adaptive immunity

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Mechanisms and Novel Therapeutic Approaches for Neurodegenerative Diseases (2nd Edition)

edited by

Fernando Cardona

submission deadline 28 Feb 2025 | Viewed by 58 | Submission Open

Keywords: neurodegenerative diseases; cellular mechanisms; molecular mechanisms; neurodegeneration models; protein misfolding; protein aggregation; neuronal death; molecular therapy; cellular therapy; therapeutics; medical chemistry; drug screening

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Platelets in Health and Disease: From Molecular Mechanisms to Therapeutic Potential

edited by Henry Nording

submission deadline 28 Feb 2025 | Viewed by 58 | Submission Open

Keywords: platelet biology; vascular immunity; atherosclerosis; therapeutic targets; biomarkers

(This special issue belongs to the Section Cell Biology and Pathology)

Microbial Metabolites and Their Impact on Gut Homeostasis

edited by

Federica Laudisi

and

Carmine Stolfi

submission deadline 28 Feb 2025 | Viewed by 57 | Submission Open

Keywords: intestinal microbiota; microbial metabolites; gut homeostasis; inflammatory response; intestinal epithelial barrier; immune response; diet

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Application of Biomedical Materials in Cancer Therapy

edited by Rui Sang

submission deadline 28 Feb 2025 | Viewed by 54 | Submission Open

Keywords: biomedical materials; cancer therapy; drug delivery systems; biomaterials synthesis; imaging agents; tissue engineering; regenerative medicine; tumor microenvironment; targeted therapy; biocompatibility

(This special issue belongs to the Section Biomedical Engineering and Materials)

Roles of T Cells in Immunotherapy, 2nd Edition

edited by

Zhan Zhou

and

Wenbin Zhao

submission deadline 28 Feb 2025 | Viewed by 50 | Submission Open

Keywords: T-cell; immunotherapy; TCR

(This special issue belongs to the Section Immunology and Immunotherapy)

Advances in Obstructive Sleep Apnea: Molecular and Translational Research

edited by Tea Galić

submission deadline 28 Feb 2025 | Viewed by 49 | Submission Open

Keywords: sleep; sleep-related breathing disorders; obstructive sleep apnea; metabolism; cardiovascular risk; glucose metabolism; inflammation mediators; sleep quality; quality of life

(This special issue belongs to the Section Molecular and Translational Medicine)

Advances in Pediatric Ocular Pathology and Treatment

edited by Hyun-jin Shin

submission deadline 28 Feb 2025 | Viewed by 48 | Submission Open

Keywords: pediatric ophthalmology; eye diseases; genetics; medical; diagnostic techniques; ophthalmological; therapeutics

(This special issue belongs to the Section Cell Biology and Pathology)

Diagnosis and Treatment of Neurodegenerative Diseases in the Era of Precision Medicine

edited by

Rohan Gupta

submission deadline 28 Feb 2025 | Viewed by 44 | Submission Open

Keywords: drug discovery and development; machine learning; precision medicine; neurodegenerative diseases; artificial intelligence; diagnostic biomarkers

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

High-Risk Pregnancy, Labor and Delivery

edited by

Salvatore Andrea Mastrolia

submission deadline 28 Feb 2025 | Viewed by 44 | Submission Open

Keywords: preterm labor; labor; delivery; pregnancy

(This special issue belongs to the Section Molecular and Translational Medicine)

Molecular and Cellular Research in Diabetes and Metabolic Diseases

edited by Miwon Ahn

submission deadline 28 Feb 2025 | Viewed by 44 | Submission Open

Keywords: insulin exocytosis; pre-diabetes; type 2 diabetes; organ cross-talk; diabetes drugs; diabetes clinical study; glucose homeostasis

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Hepatocellular Carcinoma Pathogenesis and Therapy

edited by Junyan Tao

submission deadline 28 Feb 2025 | Viewed by 40 | Submission Open

Keywords: HCC (hepatocellular carcinoma); early diagnosis; molecular pathology characteristics; molecular target therapy; combination therapy; immune checkpoint inhibitors; precision medicine; HCC heterogeneity; drug resistance; HCC risk factors

(This special issue belongs to the Section Cancer Biology and Oncology)

Recent Advances in Gut Microbiome and Heart Failure: Second Edition

edited by

Muhammad Zubair Israr

submission deadline 28 Feb 2025 | Viewed by 40 | Submission Open

Keywords: heart failure; metabolic disease; metabolomics; omics; microbiome/microbiota; gut– heart axis; novel technologies; biomarkers; therapeutics

(This special issue belongs to the Section Molecular and Translational Medicine)

Epigenetics and Metabolic Disorders

edited by Patrik Krumpolec

submission deadline 28 Feb 2025 | Viewed by 39 | Submission Open

Keywords: metabolic diseases; epigenetics; DNA methylation; histone modification; non-coding RNA (ncRNA)-mediated gene regulation; heredity; environmental factors

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Treatment of HIV Infection: Strategies, New Drugs and Drug Metabolism

edited by

Salvatore Martini

submission deadline 28 Feb 2025 | Viewed by 26 | Submission Open

Keywords: HIV; long-acting; efficacy; tolerability; adherence

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Recent Advances in Hypertension, Hypercholesterolemia and Type 2 Diabetes—2nd Edition

edited by

Tomislav Bulum

submission deadline 28 Feb 2025 | Viewed by 22 | Submission Open

Keywords: type 2 diabetes; hypertension; LDL-cholesterol; serum lipids; metabolic syndrome; cardiovascular disease; chronic complications; nephropathy

(This special issue belongs to the Section Endocrinology and Metabolism Research)

New Challenges in the Study of Diabetes and Related Complications-Pathophysiology, Prevention and Treatment

edited by Jeļizaveta Sokolovska

submission deadline 15 Mar 2025 | 3 articles | Viewed by 3683 | Submission Open

Keywords: diabetes mellitus; glucose variability; complications of diabetes; low-grade inflammation; oxidative stress; anti-oxidative response

(This special issue belongs to the Section Cell Biology and Pathology)

State-of-the-Art Drug Discovery and Development in Poland (2nd Edition)

edited by

Aleksandra Romaniuk-Drapała

submission deadline 15 Mar 2025 | 3 articles | Viewed by 2232 | Submission Open

Keywords: in silico drug target profiling; drug delivery systems; drug– drug interactions; target-based screening; phenotypic screening; pharmaceutical modeling; computational chemistry; targeted therapy; biomarkers; bioimaging

(This special issue belongs to the Section Drug Discovery, Development and Delivery)

Recent Developments in Mycobacterial Research

edited by

Vishwanath Venketaraman

submission deadline 28 Mar 2025 | Viewed by 49 | Submission Open

Keywords: Mycobacterium tuberculosis; mycobacterial; host immune responses

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Musculoskeletal Diseases: From Molecular Basis to Therapy (Volume II)

edited by

Elisa Belluzzi

and

Assunta Pozzuoli

submission deadline 31 Mar 2025 | 19 articles | Viewed by 29491 | Submission Open

Keywords: musculoskeletal diseases; bone cancer; soft tissue cancer; bone metastasis; natural compounds; anticancer drugs; osteoarthritis; joint tissues; biomarkers; inflammation; microRNAs; exosomes

(This special issue belongs to the Section Molecular and Translational Medicine)

Connections between Diabetes Mellitus, Other Metabolic and Endocrine Dysfunctions and Cardiovascular Pathologies

edited by

Cristina Tudoran

submission deadline 31 Mar 2025 | 12 articles | Viewed by 15344 | Submission Open

Keywords: diabetes mellitus; insulin resistance; metabolic syndrome; obesity; thyroid dysfunction; hormonal alterations; endothelial dysfunction; coronary artery disease; hypertension; peripheric arterial disease

(This special issue belongs to the Section Endocrinology and Metabolism Research)

Crosstalk between Depression, Anxiety, Dementia, and Chronic Pain: Comorbidity in Behavioral Neurology and Neuropsychiatry Volume III

edited by

Masaru Tanaka

and

Simone Battaglia

submission deadline 31 Mar 2025 | 6 articles | Viewed by 11388 | Submission Open

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Artificial Intelligence Applications in Cancer and Other Diseases

edited by

Raji Sundararajan

submission deadline 31 Mar 2025 | 7 articles | Viewed by 9848 | Submission Open

Keywords: artificial intelligence; machine learning; neural networks; deep learning; obesity; diabetes; cancer; other diseases; pathology; drug discovery

(This special issue belongs to the Section Biomedical Engineering and Materials)

Phenotypes and Endotypes in Interstitial Lung Diseases

edited by

Francesco Amati

submission deadline 31 Mar 2025 | 5 articles | Viewed by 8100 | Submission Open

(This special issue belongs to the Section Molecular and Translational Medicine)

Oral Squamous Cell Carcinoma: Molecular Signaling Pathways and Novel Biomarkers

edited by

Sadhna Aggarwal

submission deadline 31 Mar 2025 | 4 articles | Viewed by 5733 | Submission Open

Keywords: oral squamous cell carcinoma (OSCC); molecular signaling pathways; biomarkers; pathogenesis; targeted therapy; tumour growth; tumour invasion; angiogenesis; tumour metastasis; immune response modulation

(This special issue belongs to the Section Cancer Biology and Oncology)

In Vitro Models of Cardiovascular Diseases and Toxicity

edited by

Federico Vozzi

submission deadline 31 Mar 2025 | 3 articles | Viewed by 5644 | Submission Open

Keywords: cardiovascular diseases; tissue engineering; organ-on-chip; 3D systems; co-cultures; toxicity

(This special issue belongs to the Section Molecular and Translational Medicine)

Brain Injury and Neurodegeneration: Molecular, Functional, and Translational Approach 3.0

edited by

and

submission deadline 31 Mar 2025 | 4 articles | Viewed by 5627 | Submission Open

Keywords: brain injury; psychological stress; Parkinson’ s disease; Alzheimer’ s disease; stroke; neurodegeneration; hemorrhages; hypoxia; neuroinflammation; translational approaches; oxidative stress; COVID-19; gut– brain axis

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

The Interplay between Immunity and Microbiota in Human Health and Diseases (2nd Edition)

edited by

Laura Franza

submission deadline 31 Mar 2025 | 4 articles | Viewed by 5449 | Submission Open

Keywords: immunity; microbiota; inflammation; infection; cancer; autoimmune disorders; disease

(This special issue belongs to the Section Microbiology in Human Health and Disease)

Molecular Biomarkers of Tumors: Advancing Genetic Studies

edited by Sainan Wei and

Jing Di

submission deadline 31 Mar 2025 | 5 articles | Viewed by 4655 | Submission Open

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Pathology of Vascular Disease and Heart Failure

edited by

Pasquale Caldarola

and

Pietro Scicchitano

submission deadline 31 Mar 2025 | 3 articles | Viewed by 4517 | Submission Open

Keywords: heart failure; vascular diseases; cardiovascular pharmacology; endothelial function and biology; aortic diseases; preventive cardiology

(This special issue belongs to the Section Cell Biology and Pathology)

Photodynamic Therapy (3rd Edition)

edited by

Stefano Bacci

submission deadline 31 Mar 2025 | 4 articles | Viewed by 4121 | Submission Open

Keywords: antimicrobial photodynamic treatment; chronic wounds; inflammatory dermatoses; photobiology photochemistry; photochemotherapy; photosensitizing agents; skin cancer; oral mucosa

(This special issue belongs to the Section Immunology and Immunotherapy)

Animal Models of Human Pathology: Revision, Relevance and Refinements (3rd Edition)

edited by

Martina Perše

submission deadline 31 Mar 2025 | 3 articles | Viewed by 3860 | Submission Open

Keywords: animal models; biomarkers; human disease; pathology; translation; mechanisms; nephrology; gastroenterology; urology; neuroscience; cancer; experimental design; reproducibility; refinements

(This special issue belongs to the Section Molecular and Translational Medicine)

Understanding Diseases Affecting the Central Nervous System

edited by

Olga Koper-Lenkiewicz

and

Joanna Kamińska

submission deadline 31 Mar 2025 | 4 articles | Viewed by 3485 | Submission Open

Keywords: central nervous system pathology; biological factors; genetic factors; environmental factors; lifestyle factors; therapeutic strategies; diagnostic biomarkers; molecular pathways; neuroinflammation

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

New Insights into the Diagnosis and Treatment of Hepatocellular Carcinoma

edited by

Evangelos Koustas

submission deadline 31 Mar 2025 | 4 articles | Viewed by 3472 | Submission Open

Keywords: checkpoint inhibitors; combinatorial treatments; hepatocellular carcinoma (HCC); immunotherapy; liver cancer; therapy; targeted therapy

(This special issue belongs to the Section Cancer Biology and Oncology)

Signaling Networks and Gene Expression in Immune Cells

edited by

Santarsiero Anna

Vittoria Infantino

and Paolo Convertini

submission deadline 31 Mar 2025 | 3 articles | Viewed by 3326 | Submission Open

Keywords: cell signaling; immunometabolism; metabolic reprogramming; immunity; innate immune cells; adaptive immunity; transcriptional/post-transcriptional regulation; gene expression; inflammatory process; inflammatory diseases

(This special issue belongs to the Section Immunology and Immunotherapy)

Emerging Trends in Gastrointestinal Tract Disease Therapies

edited by

Puo-Hsien Le

, Jenwei Chou and

Chen-Shuan Chung

submission deadline 31 Mar 2025 | 2 articles | Viewed by 3108 | Submission Open

Keywords: gut microbiota; fecal microbiota transplantation; inflammatory bowel disease; advanced endoscopy; endoscopic bariatric therapy; endoscopic anti-reflux therapy natural orifice transluminal endoscopic surgery; artificial intelligence

(This special issue belongs to the Section Molecular and Translational Medicine)

3D Cell Culture Systems for Biomedical Research

edited by

Agnieszka Rusak

and

Benita Wiatrak

submission deadline 31 Mar 2025 | 3 articles | Viewed by 2988 | Submission Open

Keywords: 3D; scaffolds; spheroids; biomaterials; tumour model; bioengineering; tissue regeneration; regenerative medicine; targeted therapies; tissue mimics; angiogenesis; cancerogenesis; drug development; 3D printing; material functionalisation

(This special issue belongs to the Section Biomedical Engineering and Materials)

Inflammatory Bowel Diseases: New Diagnostic and Therapeutic Approaches

edited by

Maria Manuela Estevinho

and

Fernando Magro

submission deadline 31 Mar 2025 | 2 articles | Viewed by 2916 | Submission Open

Keywords: bowel inflammation; crohn’ s disease; endoscopy; inflammatory bowel disease; targeted therapy; ulcerative colitis

(This special issue belongs to the Section Immunology and Immunotherapy)

Glioblastoma: Pathogenetic, Diagnostic and Therapeutic Perspectives

edited by

Thi Thu Trang Nguyen

submission deadline 31 Mar 2025 | 3 articles | Viewed by 2848 | Submission Open

Keywords: drug delivery methods (TTFields; nanoparticles); immunotherapy; oncolytic virotherapy; cell metabolism (glycolysis; OXPHOS; fatty acid oxidation); epigenetic; biomarkers; gene therapy (CRISPR/Cas9)

(This special issue belongs to the Section Neurobiology and Clinical Neuroscience)

Gene Delivery and Gene Editing

edited by Kosuke Ishikawa

submission deadline 31 Mar 2025 | 2 articles | Viewed by 2341 | Submission Open

Keywords: gene delivery; gene editing; novel module; transposon; genetic engineering

(This special issue belongs to the Section Molecular Genetics and Genetic Diseases)

Displaying special issue 451-500 on page 10 of 13.

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