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Biomolecules publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Diabetes, Overweight and Obesity: From Molecular Mechanisms to Therapies Strategies

edited by

Othmar Moser

and

Harald Sourij

submission deadline 31 Dec 2024 | 1 articles | Viewed by 861 | Submission Open

Keywords: diabetes mellitus; overweight; obesity; molecular mechanisms; microbiome; liver metabolism; advanced therapy

(This special issue belongs to the Section Molecular Medicine)

Mass Spectrometry Imaging in Neuroscience

edited by Nhu Thi Ngoc Phan

submission deadline 31 Dec 2024 | Viewed by 805 | Submission Open

Keywords: mass spectrometry imaging; secondary ion mass spectrometry (SIMS); matrix-assisted laser desorption/ionization (MALDI); desorption electrospray ionization (DESI); laser ablation– inductively coupled plasma– mass spectrometry imaging (LA-ICP-MSI); multi-isotope imaging mass spectrometry (MIMS); molecular and organelle turnover; brain; neurons; synapses; neuronal stem cells; membrane lipids; synaptic proteins; neural peptides; metabolites; diseases; disorders

Therapeutic Strategies via Skeletal and Mesenchymal Stem Cells in the Cranial and Dental Fields

edited by

Takehito Ouchi

and

Taneaki Nakagawa

submission deadline 31 Dec 2024 | 1 articles | Viewed by 782 | Submission Open

Keywords: mesenchymal stem cells; tissue engineering; regenerative therapy

(This special issue belongs to the Section Molecular Medicine)

Molecular Advances in Inflammatory Bowel Disease

edited by

Antonietta Gerarda Gravina

and

Raffaele Pellegrino

submission deadline 31 Dec 2024 | 1 articles | Viewed by 695 | Submission Open

Keywords: inflammatory bowel disease; Crohn’ s disease; ulcerative colitis; biologics; quality of life; diagnostic markers; prognostic markers; drug monitoring; antibodies

(This special issue belongs to the Section Molecular Medicine)

Cellular and Molecular Mechanism of Spermatogenesis

edited by Yanhe Lue

submission deadline 31 Dec 2024 | 1 articles | Viewed by 627 | Submission Open

Keywords: spermatogenesis; regulation; biomolecules

(This special issue belongs to the Section Molecular Reproduction)

Omics Data Integration: Focusing on Molecular Biomarkers for Cancers and Diseases

edited by Cinzia Franchin

submission deadline 31 Dec 2024 | 1 articles | Viewed by 616 | Submission Open

Keywords: omics data analysis; omics data integration; biomarker discovery; bioinformatics; cancers

(This special issue belongs to the Section Biomacromolecules: Proteins)

Glycosaminoglycans (GAGs) and Mimetics—from Basic Science to Applications

edited by

Daniel Afosah

and

Rami A. Al-Horani

submission deadline 31 Dec 2024 | 1 articles | Viewed by 603 | Submission Open

Keywords: Glycosaminoglycans (GAGs); hyaluronan; heparin; chondroitin sulfate; keratan sulfate; dermatan sulfate; sulfation; GAG mimetics; GAG-binding proteins

(This special issue belongs to the Section Biomacromolecules: Carbohydrates)

Molecular and Toxicological Profiling of Drugs of Abuse—in Honor of Professor Félix Carvalho

edited by

João Pedro Silva

and

Vera Marisa Costa

submission deadline 31 Dec 2024 | Viewed by 496 | Submission Open

Keywords: toxicodynamic; toxicokinetic; amphetamine-type stimulants; cannabis and cannabinoids; cocaine; hallucinogens; new psychoactive substances; opioids; immune modulation

Molecular, Cellular, and Blood Biomarkers in Diagnosis, Prognosis, Monitoring, and Treatment

edited by

Jordi Camps

, Isabel Fort Gallifa and Xavier Gabaldó Barrios

submission deadline 31 Dec 2024 | 1 articles | Viewed by 489 | Submission Open

Keywords: biomarkers; infectious diseases; laboratory medicine; non-communicable diseases

(This special issue belongs to the Section Molecular Biology)

Bioactive Molecules: Structures, Functions and Potential Uses for Cancer Prevention and Targeted Therapies (2nd Edition)

edited by

Qingping Dou

submission deadline 31 Dec 2024 | Viewed by 359 | Submission Open

Keywords: small molecules; biomolecules; molecular targeting; natural products; cancer management

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Computational Analysis and Conformational Modeling for Protein Structure and Interaction

edited by

Clement Agoni

and

Indrani Bera

submission deadline 31 Dec 2024 | Viewed by 332 | Submission Open

Keywords: protein structure prediction; drug discovery targeting proteins; structural bioinformatics; molecular dynamics simulations; protein– protein interactions; protein– ligand binding; conformational dynamics; molecular docking studies

(This special issue belongs to the Section Biomacromolecules: Proteins)

Molecular Basis of Stress- and Trauma-Related Disorders

edited by Vanessa Nieratschker

submission deadline 31 Dec 2024 | Viewed by 308 | Submission Open

Keywords: stress; trauma; epigenetics; genetics; molecular mechanisms; transgenerational transmission; neuronal adaptations; transcriptomics; proteomics; metabolomics

(This special issue belongs to the Section Molecular Medicine)

Innovative Biomolecular Structure Analysis Techniques

edited by Tzanko I. Doukov

submission deadline 31 Dec 2024 | Viewed by 294 | Submission Open

Keywords: macromolecular crystallography; room temperature crystallography; protein ensembles; NMR; MD simulations

(This special issue belongs to the Section Molecular Structure and Dynamics)

Inorganic Polyphosphate: A Multifaceted Biomolecule

edited by

Félix A. Ruiz

submission deadline 31 Dec 2024 | Viewed by 249 | Submission Open

Keywords: polyphosphate; PolyP; polymer; phosphate

(This special issue belongs to the Section Biomacromolecules: Lipids)

State-of-the-Art Protein X-ray Crystallography

edited by Wu-Pei Su and

Hongxing He

submission deadline 31 Dec 2024 | Viewed by 245 | Submission Open

Keywords: ab initio phasing methods; X-ray crystallography; protein structural determination; image reconstruction from Fourier amplitudes; iterative projection algorithms; phasing with deep learning methods

(This special issue belongs to the Section Molecular Structure and Dynamics)

Molecular and Biochemical Mechanisms of Age-Related Macular Degeneration, Neuroophthalmological Diseases and Uveitis

edited by

Puran S. Bora

submission deadline 31 Dec 2024 | Viewed by 235 | Submission Open

Keywords: retina; neovascularization; age-related macular degeneration; uveal tissue; neuro-ocular diseases

(This special issue belongs to the Section Molecular Medicine)

Nanomaterials and Their Applications in Biomedicine

edited by

George Pasparakis

submission deadline 31 Dec 2024 | Viewed by 222 | Submission Open

Keywords: photothermal and photodynamic therapies and tumor ablation strategies; theranostics and image-guided drug delivery; biosensors; including surface-enhanced Raman scattering and metal-enhanced fluorescence; biosensors; point-of-care diagnostics and lateral-flow tests; controlled drug delivery; including delivery of RNA/DNA and other biologics; additive manufacturing and 3D/4D printing applications; antimicrobials; cell therapeutics and tissue regeneration

(This special issue belongs to the Section Biological and Bio- Materials)

The Role of MDM2 in Tumor Biology and Cancer Therapy

edited by

Ruiwen Zhang

and

John Buolamwini

submission deadline 31 Dec 2024 | Viewed by 216 | Submission Open

Keywords: MDM2; p53; targeted therapy; imunotherapy; drug resistance

(This special issue belongs to the Section Molecular Genetics)

New Insights into Autacoids in Disease

edited by

Katsutoshi Yayama

submission deadline 31 Dec 2024 | Viewed by 216 | Submission Open

Keywords: angiotensin; bradykinin; endothelin; prostaglandins; thromboxanes; leukotrienes; serotonin; histamine; angiotensin-converting enzyme; angiotensin receptor; renin; kininogen; kallikrein; cyclooxygenase; phospholipase A2

(This special issue belongs to the Section Molecular Medicine)

Molecular Effects of Environmental Pollutants on Health of Human, Animals and Plants 2.0

edited by

Marina Piscopo

submission deadline 31 Dec 2024 | Viewed by 209 | Submission Open

Keywords: health damage; reproductive health; environmental pollution; epigenetics; human; animals and plants

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Barrier Formation and Homeostasis in the Vertebrate Brain

edited by

Ramani Ramchandran

Karthikeyan Thirugnanam

and

Ankan Gupta

submission deadline 31 Dec 2024 | Viewed by 181 | Submission Open

Keywords: brain endothelial cell; pericytes; choroid plexus; retina; lymphatic; blood; astrocytes; oligodendrocytes; brain ventricle; microglia

(This special issue belongs to the Section Cellular Biochemistry)

The Endoplasmic Reticulum Stress in Yeast and Fungal Cells

edited by

Yukio Kimata

submission deadline 31 Dec 2024 | Viewed by 180 | Submission Open

Keywords: unfolded protein response; yeast; fungi; endoplasmic reticulum; protein production

(This special issue belongs to the Section Molecular Biology)

Regeneration of Annelids: From Reorganization of Lost Body Parts to Cellular and Molecular Biological Background

edited by

László Molnár

submission deadline 31 Dec 2024 | Viewed by 173 | Submission Open

Keywords: regeneration; body plan; dedifferentiation; stem cells; morphallaxis; epimorphosis; neuro-immune interactions

(This special issue belongs to the Section Cellular Biochemistry)

Antitumor Agents from Natural Sources 2024

edited by

Hang Fai (Henry) Kwok

submission deadline 31 Dec 2024 | Viewed by 171 | Submission Open

Keywords: antitumor agents; natural sources; cancer prevention and therapy

(This special issue belongs to the Section Natural and Bio-derived Molecules)

The Role of Non-coding RNAs in Health and Disease

edited by

Narasimman Gurusamy

submission deadline 31 Dec 2024 | Viewed by 153 | Submission Open

Keywords: non-coding RNA; microRNA (miRNA); long noncoding RNA (lncRNA); circular RNA (circRNA); gene expression regulation; epigenetic modifications

(This special issue belongs to the Section Molecular Genetics)

Combination Therapies Involving MicroRNA Modulation: Synergistic Approaches for Enhanced Anticancer Effects

edited by

Joanna Szczepanek

and

Andrzej Tretyn

submission deadline 31 Dec 2024 | Viewed by 151 | Submission Open

Keywords: microRNA (miRNA); targeted therapy; cancer

The Development of Translational Cancer Research: In Honor of a Pioneering Professor, Ulrik Ringborg

edited by Ingemar Ernberg and Stephan Mielke

submission deadline 31 Dec 2024 | Viewed by 147 | Submission Open

Keywords: translational cancer research; tumor cell biology; precision cancer medicine

(This special issue belongs to the Section Molecular Medicine)

Bioinspired and Biomimicking Materials for Biomedical Applications: Second Edition

edited by

Bahman Anvari

submission deadline 31 Dec 2024 | Viewed by 147 | Submission Open

Keywords: biomedical and biological imaging; biophotonics; biosensors; cell-based therapy; delivery systems; theranostics

Applications of NMR Spectroscopy in Structure-Based Drug Discovery

edited by Alexander L. Breeze and Reto Walser

submission deadline 31 Dec 2024 | Viewed by 146 | Submission Open

Keywords: NMR; structural biology; structure-based drug discovery; fragment screening; lead generation

(This special issue belongs to the Section Molecular Structure and Dynamics)

Peptide and Metabolite Self-Assembly: Physiology, Pathology, Biomaterials and Their Biomedical Applications

edited by

Kuo Zhang

and

Annarita Falanga

submission deadline 31 Dec 2024 | Viewed by 142 | Submission Open

Keywords: peptide and metabolite; self-assembly; physiology and pathology; biomaterials; biomedicine

(This special issue belongs to the Section Molecular Structure and Dynamics)

Role of Glutathione Peroxidase in Health and Disease

edited by R Steve Esworthy

submission deadline 31 Dec 2024 | Viewed by 131 | Submission Open

Keywords: GPX1; GPX2; GPX3; GPX4; GPX5; GPX6; GPX7; GPX8; selenium; cancer; pathology

Transcription Factor E2F in Normal and Cancer Cells

edited by

Kiyoshi Ohtani

submission deadline 31 Dec 2024 | Viewed by 119 | Submission Open

Keywords: E2F; RB; p53; cancer; tumor suppression

(This special issue belongs to the Section Biological Factors)

Tumour Suppressor Genes: The Guardians of Cell Integrity

edited by

Nicola Manfrini

submission deadline 31 Dec 2024 | Viewed by 114 | Submission Open

Keywords: cell cycle; cell growth; cell integrity; cell proliferation; DNA damage; genome integrity; protein homeostasis; migration; invasion; metastasis; apoptosis; autophagy

Biomolecules from Natural Products: Anti-inflammatory and Anti-allergic Activities: 2nd Edition

edited by

Chi-Feng Hung

submission deadline 31 Dec 2024 | Viewed by 112 | Submission Open

Keywords: anti-inflammation; anti-allergic; natural product; anti-aging

(This special issue belongs to the Section Natural and Bio-derived Molecules)

Alcohol-Related Organ Damage: Mechanisms, Outcomes, and Treatment Modalities

edited by

Natalia Osna

and

Kusum K. Kharbanda

submission deadline 31 Dec 2024 | Viewed by 107 | Submission Open

Keywords: alcoholic liver disease (ALD); steatohepatitis; fibrosis; cirhosis; parenhymal and non-parenhymal liver cells; brain; gut; lungs; immune responses; oxidative stress; methylation; viral infections; post-translational protein modifications; treatment of ALD

(This special issue belongs to the Section Molecular Medicine)

Recent Advances in Adduct Science

edited by Yukari Totsuka and Haruhiko Sugimura

submission deadline 31 Dec 2024 | Viewed by 107 | Submission Open

Keywords: adductomics; protein- or nucleic acid-adducts; biomarkers; exposome; genomic mutations; disease etiology; preventive strategies; drug discovery; risk assessment

Protein Misfolding Diseases: Molecular Mechanisms and Therapeutic Strategies

edited by Priyanka Joshi and Michele Perni

submission deadline 31 Dec 2024 | Viewed by 100 | Submission Open

Keywords: protein aggregation; protein misfolding; biomolecular condensation; chemical kinetics; cellular homeostasis; small molecules; antibody therapeutics; drug discovery; neurodegeneration; neurodegenerative diseases

(This special issue belongs to the Section Molecular Structure and Dynamics)

Advances in Host-Derived Cytotoxic Agents

edited by

Jürgen Arnhold

submission deadline 31 Dec 2024 | Viewed by 100 | Submission Open

Keywords: cytotoxic agents; antagonizing principles; inflammation; disease progression

Novel Antimicrobial Strategies for Animal Health

edited by

Anna Aris

and

Elena Garcia-Fruitos

submission deadline 31 Dec 2024 | Viewed by 86 | Submission Open

Keywords: antimicrobial alternatives; antimicrobial resistance; animal health; infectious disease

(This special issue belongs to the Section Molecular Medicine)

Health and Environmental Effect of Advanced Materials and Fine Particles: 2nd Edition

edited by

II Je Yu

submission deadline 31 Dec 2024 | Viewed by 86 | Submission Open

Keywords: advanced materials; fine particles; nanoparticles; nanomaterials; ultrafine particles; health effect; environmental effect; risk assessment; toxicity; exposure; biomaterials

The Structure and Function of Neurotransmitter Receptors and Transporters: From Molecular Biology to Translational Research

edited by Riccardo Fesce

submission deadline 31 Dec 2024 | Viewed by 80 | Submission Open

Keywords: neurotransmitters; receptors; neurotransporters; structure– function relationship; neuropharmacology

(This special issue belongs to the Section Molecular Biology)

Elucidating the Roles of Chromatin in Genomic Processes

edited by

Daniel M. Czajkowsky

and Meijun Liu

submission deadline 31 Dec 2024 | Viewed by 78 | Submission Open

Keywords: nucleosome positioning and occupancy; histone modifications; histone variants; nucleosome chaperones; nucleosome remodelers; insulator proteins; CTCF and cohesin; cis-regulatory elements; 3D genome structure; chromatin dynamics

Molecular Mechanisms in New Strategies for Longevity

edited by

Yoshinari Uehara

submission deadline 31 Dec 2024 | Viewed by 77 | Submission Open

Keywords: longevity; atherosclerosis; lipids; exercise; foods

The Next Generation of Proteomics for Precision Medicine: Second Edition

edited by

Towia Libermann

submission deadline 31 Dec 2024 | Viewed by 66 | Submission Open

Keywords: proteomics; biomarkers; next-generation protein sequencing; diagnostics; protein quantitative trait locus; systems biology; precision medicine

(This special issue belongs to the Section Biomacromolecules: Proteins)

Biomarkers of Ocular Allergy and Dry Eye Disease, 2nd Edition

edited by

Anat Galor

submission deadline 31 Dec 2024 | Viewed by 55 | Submission Open

Keywords: ocular allergy; dry eye disease; Sjö gren's syndrome; biomarker; prognostic biomarkers; diagnostic biomarkers

Integrating Genetics, Immune Dysregulation, and the Gut Microbiome: Advances in Elucidating IBD Pathophysiology and Emerging Therapeutic Strategies

edited by Peter W. Jurutka and

Todd R. Sandrin

submission deadline 31 Dec 2024 | Viewed by 51 | Submission Open

Keywords: microbiome; biomarkers; Crohn’ s disease; ulcerative colitis; indeterminate colitis; multiomics; gastrointestinal (GI disease); immunology; gut– brain axis; neuropsychology

(This special issue belongs to the Section Molecular Genetics)

New Insights into Cytochrome P450s, 2nd Edition

edited by

Philippe Urban

submission deadline 31 Dec 2024 | Viewed by 48 | Submission Open

Keywords: cytochrome P450 (P450); cytochrome b5; NADPH-P450 oxidoreductase (CPR); heme; flavin; P450 structure; P450 catalytic activities; prokaryotic P450; eukaryotic P450; viral P450; drug metabolism; detoxification; plant secondary metabolisms; membrane protein– protein complex; AlphaFold; AlphaFold2; regulation of P450 transcription; catalytic cavities; substrate access channels; prediction of protein– protein complexes; P450 interaction on P450– CPR complexes; tripartite P450– CPR– cytochrome b5 complex

Prebiotics and Probiotics in Health and Disease: Looking at the Future

edited by

Pio Maria Furneri

Virginia Fuochi

and

Giovanna Furneri

submission deadline 7 Jan 2025 | Viewed by 350 | Submission Open

Keywords: probiotics; live biotherapeutic product (LBP); next-generation probiotic (NGP); prebiotic; synbiotic/symbiotic; pharmabiotics; post-biotics; paraprobiotic/ghost probiotics/inactivated probiotics; probioceuticals/probiotaceuticals; biogenic; gut balance; gut– brain axis; vaginal homeostasis; vaginal microbiota modification or augmentation; oral microbiota; skin microbiota; new therapeutic approaches using bacteria; psychobiotics

Biosynthesis and Function of Thyroid Hormones

edited by

Josef Koehrle

and Eva K. Wirth

submission deadline 10 Jan 2025 | Viewed by 138 | Submission Open

Keywords: thyroid gland; thyroid follicle; TH release; iodide; deiodinase; TH transmembrane transport; TH receptors; intracellular TH binding proteins; thyroglobulin; sodium– iodide symporter; thyroperoxidase; dual oxidase; thyroid-relevant trace elements

(This special issue belongs to the Section Biological Factors)

Circular RNAs: Functions, Applications and Prospects: 2nd Edition

edited by

William W. Du

and Feiya Li

submission deadline 15 Jan 2025 | 2 articles | Viewed by 3064 | Submission Open

Keywords: circular RNAs; circRNA; function; application; disease

(This special issue belongs to the Section Biomacromolecules: Nucleic Acids)

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