Advances in Portable and Wearable Sensing Systems for Biochemical Monitoring

A special issue of Biosensors (ISSN 2079-6374). This special issue belongs to the section "Wearable Biosensors".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 1825

Special Issue Editors

Biosensor National Special Laboratory, Key Laboratory for Biomedical Engineering of Education Ministry, Department of Biomedical Engineering, Zhejiang University, Hangzhou 310027, China
Interests: biosensors; smartphone based biosensors; wearable biosensors; electrochemical sensor; optical biosensors; healthcare monitoring; new electroanalytical methodology applied to environmental, food, and health fields
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Guest Editor
School of Disaster and Emergency Medicine, Tianjin University, Tianjin, China
Interests: biosensors; wearable sensor; flexible biosensing; electrochemical sensor; optical biosensor; healthcare monitoring

Special Issue Information

Dear Colleagues,

In recent years, portable and wearable sensing technologies have been one of the most rapidly developing hightech and interdisciplinary hotspots. The emerging wearable and portable sensing technologies are widely expected to meet the growing needs and challenges in healthcare due to their low cost, simple operation, easy readout, and respectable detection performance. Portable and wearable sensing systems have already accomplished some demonstration applications, such as biomarker detection in blood, urine, cerebrospinal fluid, sweat detection, wound condition monitoring and treatment, etc. It provides an alternate avenue to clinical diagnostics. With continued innovation and development, biomaterials, nanomaterials, flexible materials, compact sensing systems, and novel detecting techniques have all contributed to the substantial advancement of portable and wearable systems. However, there are still a lot of obstacles to overcome and room for improvement in fully utilizing the capabilities of portable and wearable sensing devices. Therefore, both breathable and biocompatible materials, sampling preparation techniques, stable and accurate sensors and their arrays, long-term power supply systems, stable data acquisition and analysis terminals, fully flexible electronic circuits, miniaturized detection and treatment integration systems, detection and analysis of multiple physiological parameters, etc., are key problems in future portable and wearable system research. Advances in any of these areas will greatly boost the development of wearable systems in the medical field.

The aim of this Issue on “Advances in Portable and Wearable Sensing Systems for Biochemical Monitoring” is to highlight recent methodological advances in portable and wearable biosensors and systems for health monitoring and novel materials and platforms for biochemical parameter detection, from the design of new biosensors and devices to the experimental verification, up to the point-of-care testing and wearable applications. Original research articles and review papers are welcome.

We look forward to receiving your outstanding research outcomes.

Dr. Yanli Lu
Dr. Zetao Chen
Guest Editors

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Keywords

  • portable sensing system
  • wearable system
  • bioelectronics
  • biochemical monitoring
  • self-powered biosensors
  • in situ biosensing
  • epidermal patches
  • implantable sensors
  • ingestible sensors
  • biosensors

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Published Papers (1 paper)

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Research

13 pages, 1266 KiB  
Article
A Wireless and Wearable Multimodal Sensor to Non-Invasively Monitor Transabdominal Placental Oxygen Saturation and Maternal Physiological Signals
by Thien Nguyen, Soongho Park, Asma Sodager, Jinho Park, Dahiana M. Gallo, Guoyang Luo, Roberto Romero and Amir Gandjbakhche
Biosensors 2024, 14(10), 481; https://doi.org/10.3390/bios14100481 - 7 Oct 2024
Viewed by 1399
Abstract
Poor placental development and placental defects can lead to adverse pregnancy outcomes such as pre-eclampsia, fetal growth restriction, and stillbirth. This study introduces two sensors, which use a near-infrared spectroscopy (NIRS) technique to measure placental oxygen saturation transabdominally. The first one, an NIRS [...] Read more.
Poor placental development and placental defects can lead to adverse pregnancy outcomes such as pre-eclampsia, fetal growth restriction, and stillbirth. This study introduces two sensors, which use a near-infrared spectroscopy (NIRS) technique to measure placental oxygen saturation transabdominally. The first one, an NIRS sensor, is a wearable device consisting of multiple NIRS channels. The second one, a Multimodal sensor, which is an upgraded version of the NIRS sensor, is a wireless and wearable device, integrating a motion sensor and multiple NIRS channels. A pilot clinical study was conducted to assess the feasibility of the two sensors in measuring transabdominal placental oxygenation in 36 pregnant women (n = 12 for the NIRS sensor and n = 24 for the Multimodal sensor). Among these subjects, 4 participants had an uncomplicated pregnancy, and 32 patients had either maternal pre-existing conditions/complications, neonatal complications, and/or placental pathologic abnormalities. The study results indicate that the patients with maternal complicated conditions (69.5 ± 5.4%), placental pathologic abnormalities (69.4 ± 4.9%), and neonatal complications (68.0 ± 5.1%) had statistically significantly lower transabdominal placental oxygenation levels than those with an uncomplicated pregnancy (76.0 ± 4.4%) (F (3,104) = 6.6, p = 0.0004). Additionally, this study shows the capability of the Multimodal sensor in detecting the maternal heart rate and respiratory rate, fetal movements, and uterine contractions. These findings demonstrate the feasibility of the two sensors in the real-time continuous monitoring of transabdominal placental oxygenation to detect at-risk pregnancies and guide timely clinical interventions, thereby improving pregnancy outcomes. Full article
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