Polyphenols in Cancer Treatment
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (9 June 2023) | Viewed by 3871
Special Issue Editors
Interests: breast cancer; EMT; obesity; cytokines; inflammation
Special Issues, Collections and Topics in MDPI journals
Interests: microbiology; compound; polyphenol
2. Departamento de Bioquímica, ICBS, UFRGS, Porto Alegre, RS, Brazil
Interests: apoptosis; mitochondria; respiratory chain; antioxidant; redox biology; mitochondrial biogenesis; mitochondrial is research interests include natural compounds; polyphenols; mitochondria-related signaling; oxidative stress; neuroinflammation; neurotoxicology; neurodege; mitochondrial medicine
Special Issue Information
Dear Colleagues,
Polyphenols are a large family of chemical compounds broadly distributed in nature and characterized by the presence of multiple phenol structures in their molecules. They are mainly synthesized in plants as secondary metabolites to protect against pathogens or ultraviolet light. Naturally derived polyphenols are an integral part of the human diet and have been used in traditional medicine for their pleiotropic (antiseptic, anti-inflammatory, antioxidant, etc.) properties. Many natural polyphenols and their synthetic analogs have been demonstrated to possess anti-carcinogenic activities, such as suppressing cancer cell proliferation, adhesiveness, invasiveness, metastasis, and tumor angiogenesis. They act through the modulation of multiple signaling pathways and the expression of cancer-regulating genes. Moreover, polyphenolic compounds exhibit antioxidant activities affecting the levels of reactive oxygen species (ROS) in cells, thus regulating cell proliferation, survival, and apoptosis.
This Cancers special issue focuses on publishing a broad range of research (both basic and preclinical studies) on the effect of various polyphenolic compounds in cancer prevention, initiation, and progression.
Dr. Dimiter B. Avtanski
Dr. Sonali Sengupta
Prof. Dr. Marcos Roberto de Oliveira
Guest Editors
Manuscript Submission Information
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Keywords
- polyphenols
- cancer prevention
- cancer treatment
- oxidative stress
- antioxidants