Personalized Medicine: Recent Progress in Cancer Therapy
A special issue of Cancers (ISSN 2072-6694).
Deadline for manuscript submissions: closed (29 February 2020) | Viewed by 69475
Special Issue Editors
Interests: palliative care; cancer pain; opioids; NMDA; symptoms in cancer
Interests: neuro-oncology; palliative care; personolised medicine
Interests: neuropathic pain; NMDA; opioids; cancer pain; spinal cord; nociception; mechanism of action; pharmacology of pain
Special Issue Information
Dear Colleagues,
Personalized medicine (PM) or precision medicine in oncology is an emerging approach for tumor treatment and prevention, which takes into account inter- and intra-tumoral variability in genes, tumor (immune) environment, and lifestyle and morbidities of each person diagnosed with cancer. PM has the potential to tailor therapy towards the oncogenic drivers of the tumor and modulate the tumor immune environment, not only attempting to optimize tumor response, but also taking into account therapy-induced toxicities for each specific patient. In this way, optimized tumor response is combined with the preservation of organ function and quality of life, ensuring better patient care.
Biomarker development is a rapidly evolving field in PM and makes it possible to not only predict prognosis, but also to predict treatment response. Predictive biomarker models are not only defined by serum markers, but also by different imaging modalities (CT, MR, nuclear imaging modalities), creating multimodal (non-invasive) predictive platforms identifying the molecular fingerprint of the tumor.
Finetuning of predictive models will enable the construction of tumor-tailored treatment plans and improve prognostic models, which will facilitate shared decision-making, allowing for a patient-tailored treatment plan.
By enabling each patient to receive earlier diagnoses, risk assessments, and optimal treatments, PM holds promise for improving health care while also lowering costs.
This Special Issue will highlight recent advances in personalized medicine in treating cancer and its accompanying symptoms.
Prof. Dr. Marieke H.J. van den Beuken-van Everdingen
Dr. Ann Hoeben
Prof. Dr. Elbert A.J. Joosten
Guest Editors
Manuscript Submission Information
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Keywords
- personalized medicine
- genetics
- epigenetics
- immunotherapy
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