Organoids as an Experimental Tool
A special issue of Cells (ISSN 2073-4409). This special issue belongs to the section "Tissues and Organs".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 237
Special Issue Editors
Interests: liver fibrosis; liver cell subpopulations; organoids; animal models; TGF-β; PDGF; metals; mass spectrometry; biomarkers
Special Issues, Collections and Topics in MDPI journals
Interests: liver disease; in vitro models of liver fibrosis; PSC-derived liver cells; translational medicine; siRNA/miRNAs
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Organoids are self-organized three-dimensional tissue cultures derived either from pluripotent stem cells; they can be sourced from embryonic stem cells, induced pluripotent stem cells, or tissue-derived stem cells from a specific organ. In addition, they may also be derived from progenitor or differentiated cells from healthy or diseased tissues. These cultures can replicate the complexity of an organ or focus on specific aspects of it. As a result, these three-dimensional “mini-organs” can provide valuable insights into the biological processes within an organ. They have become a powerful in vitro research tool that maintains the genetic and phenotypic characteristics of organs in vivo. The applications of organoids include modeling the development and diseases and investigating their potential for drug development and personalized medicine. Furthermore, they have shown great promise in regenerative medicine and offer a non-animal-based alternative for basic and translational research.
In this Special Issue of Cells, we invite you to contribute original research articles, reviews, or communications on all aspects related to the theme of “Organoids as an Experimental Tool”. Expert articles describing the mechanistic, functional, cellular, biochemical, or general aspects of organoid cultures and their application in basic and translational science are encouraged.
Prof. Dr. Ralf Weiskirchen
Dr. Leo A. Van Grunsven
Dr. Anjali A. J. Roeth
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Cells is an international peer-reviewed open access semimonthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- organoid culture models
- primary cell and cancer spheroid models
- organotypic models
- organoid research for animal replacement (3R)
- chip-based methods
- general 3D cell culture protocols
- in silico approaches
- microinjection apical-out organoids
- organoid manipulation techniques
- organoid intelligence
- organoids in diagnostics
- imaging in organoids
