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Diagnostics
Special Issues
Diagnosis and Prognosis of Urological Diseases
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Diagnosis and Prognosis of Urological Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Pathology and Molecular Diagnostics".

Deadline for manuscript submissions: 30 November 2024 | Viewed by 1477

Special Issue Editor

Dr. Vineet Gauhar

E-Mail Website
Guest Editor
Department of Urology, Ng Teng Fong General Hospital, National University Health System, Singapore, Singapore
Interests: urology

Special Issue Information

Dear Colleagues,

This Special Issue is dedicated to advancing the diagnosis and prognosis of urological diseases. We welcome a diverse range of contributions, including reviews, original research articles, case reports, interesting images, and guidelines, all aiming to advance our understanding of urological diseases.

Dr. Vineet Gauhar
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • urological diseases
  • diagnosis
  • prognosis
  • marker
  • urothelial carcinoma

Published Papers (2 papers)

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Research

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10 pages, 865 KiB  
Article
The Diagnostic Value of Soluble Triggering Receptor Expressed on Myeloid Cells for Patients with Acute Stone Pyelonephritis
by Metin Özsoy, Miraç Ataman, Serhat Kazım Şahin, İbrahim Şenocak, Artuner Varlibaş, Ercan Yuvanç, Aydın Çifci, Mustafa Kemal Başaralı, Gül Kırtıl and Erdal Yilmaz
Diagnostics 2024, 14(7), 777; https://doi.org/10.3390/diagnostics14070777 - 7 Apr 2024
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Abstract
Soluble triggering receptor expressed on myeloid cells (sTREM-1) is a new biomarker that can be used for the diagnosis and monitoring of urinary system infections. This study aimed to evaluate the diagnostic performance of serum sTREM-1 in patients with a diagnosis of acute [...] Read more.
Soluble triggering receptor expressed on myeloid cells (sTREM-1) is a new biomarker that can be used for the diagnosis and monitoring of urinary system infections. This study aimed to evaluate the diagnostic performance of serum sTREM-1 in patients with a diagnosis of acute stone pyelonephritis (ASP). This prospective study included 46 patients with a diagnosis of ASP and a control group of 23 individuals without urinary system infection. Blood samples were taken from participants upon hospital admission, and basal serum sTREM-1 levels were analyzed using the ELISA method. Serum sTREM-1 concentrations were measured after treatment of ASP patients. Basal leukocyte counts, C-reactive protein (CRP) levels, procalcitonin (PCT), and sTREM-1 (98.6 vs. 68.4 pg/mL, p < 0.001) levels were higher in the ASP group compared to the control group. After treatment, the median leukocyte counts, PCT, and sTREM-1 levels decreased and were similar to those of the control group. The median CRP level also decreased after treatment, but it remained higher than that of the control group. In predicting patients with ASP, the baseline sTREM-1 exhibited a sensitivity of 74.6% and a specificity of 78.2%, while its diagnostic performance was lower than that of leukocyte counts, CRP, and PCT. Despite the findings that levels of sTREM-1 were higher upon hospital admission in patients with ASP and significantly decreased after treatment, the utility of sTREM-1 as a biomarker for predicting patients with ASP remains constrained when compared to established inflammatory markers. Full article
(This article belongs to the Special Issue Diagnosis and Prognosis of Urological Diseases)
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13 pages, 1865 KiB  
Case Report
Small Bowel Perforation Due to Renal Carcinoma Metastasis: A Comprehensive Case Study and Literature Review
by Đorđe Todorovic, Bojan Stojanovic, Milutinovic Filip, Đorđe Đorđevic, Milos Stankovic, Ivan Jovanovic, Marko Spasic, Bojan Milosevic, Aleksandar Cvetkovic, Dragce Radovanovic, Marina Jovanovic, Bojana S. Stojanovic, Damnjan Pantic, Danijela Cvetkovic, Dalibor Jovanovic, Vladan Markovic and Milica Dimitrijevic Stojanovic
Diagnostics 2024, 14(7), 761; https://doi.org/10.3390/diagnostics14070761 - 3 Apr 2024
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Abstract
This case report presents a unique instance of small bowel perforation caused by solitary metastasis from renal cell carcinoma (RCC), a rare and complex clinical scenario. The patient, a 59-year-old male with a history of RCC treated with nephrectomy four years prior, presented [...] Read more.
This case report presents a unique instance of small bowel perforation caused by solitary metastasis from renal cell carcinoma (RCC), a rare and complex clinical scenario. The patient, a 59-year-old male with a history of RCC treated with nephrectomy four years prior, presented with acute abdomen symptoms. Emergency diagnostic procedures identified a significant lesion in the small intestine. Surgical intervention revealed a perforated jejunal segment due to metastatic RCC. Postoperatively, the patient developed complications, including pneumonia and multi-organ failure, leading to death 10 days after surgery. Histopathological analysis confirmed the metastatic nature of the lesion. This case underscores the unpredictable nature of RCC metastasis and highlights the need for vigilance in post-nephrectomy patients. The rarity of small bowel involvement by RCC metastasis, particularly presenting as perforation, makes this case a significant contribution to medical literature, emphasizing the challenges in the diagnosis and management of such atypical presentations. Full article
(This article belongs to the Special Issue Diagnosis and Prognosis of Urological Diseases)
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