Editorial Board Members’ Collection Series: New Insights into Neuroproteins
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (30 June 2024) | Viewed by 473
Special Issue Editors
Interests: neurodegeneration; neuroinflammation; neurodegenerative diseases; neurodevelopmental disorders; tumor markers; specific proteins
Special Issues, Collections and Topics in MDPI journals
Interests: neurodegeneration; neuroinflammation; multiple sclerosis; amyotrophic lateral sclerosis; animal models of neural diseases; neural biomarkers; calcium-binding neuroproteins; S100B protein
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Owing to their complex structure, proteins are natural candidates for fulfilling key roles in cells and organs.
In particular, regardless of the often-unsuccessful outcomes in attempts to individuate proteins specific to the nervous system, which are specifically responsible for neural functions, these proteins (neuroproteins) have been shown to play roles which are especially relevant to this system.
Proteins such as S100B, Glial Fibrillary Acidic Protein, and Neuron-Specific Enolase have been shown to be useful cell markers. In addition, their levels in biological fluids are currently used to monitor neural disorders. Other molecules, such as alpha-synuclein and amyloid proteins, are regarded as hallmarks of several neurodegenerative disorders. Damage/Danger-Associated Molecular Pattern proteins and protein complex inflammasomes are also known to play a key role in neuroinflammatory processes, which is especially important in this system for their pathological implications. In this respect, specific receptors for these molecules are also obviously proteins in nature, such as the Receptor for Advanced Glycation-End Product and Toll-like Receptors in general.
This Special Issue will highlight novel findings in the form of original research articles or reviews dealing with different aspects of neuroprotein biology (in general and with reference to specific neuroproteins), including mechanistic insights and neuroproteins’ role in cells at the molecular level (e.g., gene expression and epigenetic studies, post-translational modifications, regulation of cell processes). Articles dealing with alterations in neuroproteins’ structure and function in human diseases, including their putative role(s) as pathological biomarkers and/or therapeutic targets, are especially welcome.
Prof. Dr. Barbara Mroczko
Prof. Dr. Fabrizio Michetti
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. International Journal of Molecular Sciences is an international peer-reviewed open access semimonthly journal published by MDPI.
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Keywords
- neuroproteins
- S100B
- glial fibrillary acidic protein
- neuron-specific enolase
- alpha-synuclein
- amyloid proteins
