Molecular Informatics and Genomics of Alzheimer’s Disease
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Molecular Neurobiology".
Deadline for manuscript submissions: closed (30 September 2024) | Viewed by 910
Special Issue Editor
Interests: ageing; Alzheimer’s disease; bioinformatics; RNA-Seq; Parkinson’s disease
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Alzheimer’s disease (AD) is the most prevalent neurological disease worldwide and is a major risk factor for the aging of the human brain. Unfortunately, there are currently no effective treatment methods nor early detection methods, and the underlying molecular mechanisms of the disease remain poorly understood. Global bulk gene expression profiling has suggested that the disease is governed by diverse transcriptional regulatory networks, which we can resolve into disease-related differentially expressed cell-type specific genes through bioinformatic/statistical analyses. These may include ANOVA, classification methods, and network and gene ontology analyses. An enhanced understanding of the disease may enable genomic interventions to be performed.
The aim of this Special Issue is to collect the latest molecular informatics and genomics research on Alzheimer’s disease. We invite authors to submit research articles and/or review articles that fulfil this purpose. All research articles or reviews should present research at the molecular level, as well as verified experiments.
Dr. Lilach Soreq
Guest Editor
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Keywords
- Alzheimer’s disease
- bioinformatics
- brain
- single cell RNASeq
- genomics
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