Functional Roles of Epithelial and Endothelial Cells
A special issue of International Journal of Molecular Sciences (ISSN 1422-0067). This special issue belongs to the section "Biochemistry".
Deadline for manuscript submissions: 30 November 2024 | Viewed by 801
Special Issue Editors
2. Regenerative Medicine Division, CHU de Québec—Université Laval Research Centre, Québec, QC G1J 1Z4, Canada
3. Université Laval Research Center on Experimental Organogenesis/LOEX, Québec, QC G1J 1Z4, Canada
Interests: regenerative medicine; tissue engineering; cell biology; cell therapy; gene therapy; cornea; skin
Special Issues, Collections and Topics in MDPI journals
2. Département d’Ophtalmologie, Faculté de Médecine, Université Laval, Québec, QC G1V 0A6, Canada
3. Centre de Recherche en Organogénèse Expérimentale de l’Université Laval/LOEX, Hôpital Enfant-Jésus, 1401 18e Rue, Québec, QC G1V 0A6, Canada
Interests: cornea; tissue engineering
Special Issue Information
Dear Colleagues
Epithelial cells cover the surfaces of the body. For those that come into contact with the outside world, such as the skin and cornea, the epithelium protects the inner layers from external injuries that can arise from chemical, biological or physical insults. The importance of the epithelium is reinforced by the fact that the failed rapid closure of a wound can result in complications, such as scars, ulcers and infections. On the other hand, endothelial cells cover the inner surface of blood vessels (or the inner surface of the cornea for this specific tissue), forming a barrier that regulates exchanges between two structures. Apart from blood flow, the endothelium also plays key roles in immunology, inflammation, and angiogenesis. In the case of the corneal endothelium, endothelial dysfunctions result in excess fluid entering the stroma, causing vision loss.
In this Special Issue, reviews and articles will demonstrate the importance of epithelial and endothelial functionality in tissue homeostasis, mainly but not restricted to the skin and cornea, using 2D (cell cultured) and 3D (tissue-engineered) models. Topics related to the regulation of cellular processes, intercellular communication, signaling pathways, pump-leak balance, and barrier functionality are welcomed.
Prof. Dr. Lucie Germain
Prof. Dr. Stéphanie Proulx
Guest Editors
Manuscript Submission Information
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Keywords
- epithelial cells
- wound healing
- endothelial cells
- skin
- cornea
- functionality
- barrier
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