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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Cancer Biology: From Genetic Aspects to Treatment

edited by

Silvia Cantara

submission deadline 31 Oct 2024 | 6 articles | Viewed by 8011 | Submission Open

Keywords: cancer biology; cancer biomarker; cancer progression; cancer metastasis; genetic of cancer

(This special issue belongs to the Section Molecular Oncology)

Plant Omics: Sensing, Signaling, Regulation and Homeostasis

edited by

Margherita-Gabriella De Biasi

submission deadline 31 Oct 2024 | 5 articles | Viewed by 7436 | Submission Open

Keywords: plant homeostasis; omics; transcriptomics; metabolomics; proteomics; genomics; ionomics; environmental stress; regulatory mechanisms; metabolic processes; systems biology

(This special issue belongs to the Section Molecular Plant Sciences)

(Meta)Genomic, Functional, Structural and Evolutionary Analysis of Transport Systems

edited by

Arturo Medrano-Soto

, Milton Saier and Gabriel Moreno-Hagelsieb

submission deadline 31 Oct 2024 | 3 articles | Viewed by 7292 | Submission Open

Keywords: molecular transport; transport mechanisms; evolution; families and superfamilies; genomics; metagenomics; 3D structural insights; bioinformatics

(This special issue belongs to the Section Molecular Biology)

Advances in Coagulation and Anticoagulation

edited by

Vance G. Nielsen

submission deadline 31 Oct 2024 | 4 articles | Viewed by 7030 | Submission Open

Keywords: coagulation; anticoagulation; procoagulant; anticoagulant; molecular mechanism

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Mechanisms of Neurological and Psychiatric Disease: A Decade of Progress

edited by

Giuseppina Martella

submission deadline 31 Oct 2024 | 5 articles | Viewed by 6960 | Submission Open

Keywords: Alzheimer's and Parkinson's diseases; epilepsy; migraine; essential tremors; stroke; depression; anxiety disorders; cognitive impairment

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Pathogenesis and Diagnostics of Lung Diseases

edited by

Amanda Iglesias

submission deadline 31 Oct 2024 | 4 articles | Viewed by 6873 | Submission Open

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Cancer Stem Cells in Solid Tumors

edited by

Jelena Milasin

submission deadline 31 Oct 2024 | 3 articles | Viewed by 6782 | Submission Open

Keywords: CSC characterization; genetic and epigenetic regulators of CSCs; tumor microenvironment; energy/oxidative metabolism; exosomes; microRNAs; treatment resistance; targeting CSCs; differentiation therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Role of Vitamin D in Human Health and Diseases 4.0

edited by

Loredana Bergandi

and

Francesca Silvagno

submission deadline 31 Oct 2024 | 4 articles | Viewed by 6726 | Submission Open

Keywords: vitamin D; vitamin D receptor; health; disease; inflammation; gene transcription; cell metabolism; differentiation; vitamin D deficiency; vitamin D supplementation

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Advances in Ionic Liquids and Their Pharmaceutical Applications

edited by

Marieta L.C. Passos

and

Maria Lúcia M.F. Sousa Saraiva

submission deadline 31 Oct 2024 | 3 articles | Viewed by 6559 | Submission Open

Keywords: ionic liquid; active pharmaceutical ingredient; drug delivery; human toxicity; environmental impact; pharmaceutical industry; pharmaceutical efficiency

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Progression of Genome-Related Diseases

edited by

Salvatore Saccone

and

Francesco Calì

submission deadline 31 Oct 2024 | 6 articles | Viewed by 6103 | Submission Open

Keywords: next-generation sequencing; genetic diseases; multifactorial diseases; diagnostic tolls; human health

(This special issue belongs to the Section Molecular Genetics and Genomics)

Molecular Research on Skeletal Muscle Biology

edited by

Atsushi Asakura

submission deadline 31 Oct 2024 | 6 articles | Viewed by 5971 | Submission Open

Keywords: skeletal muscle; muscular dystrophy; satellite cell; muscle regeneration; myofibrosis; exercise

(This special issue belongs to the Section Molecular Biology)

Redox Physiology in Biomedicine and Ecophysiology: The Influence of Various Substances on the Redox Regulation of Cell Metabolism, 2nd Edition

edited by

Slađan Pavlović

submission deadline 31 Oct 2024 | 3 articles | Viewed by 5928 | Submission Open

Keywords: redox-signalling pathways; antioxidative and hypoglicemic effects of plant extracts; prooxidant/antioxidant status in the cells; redox active trace metals; reproductive health of women and men: infertility/sterility; xenobiotics in aquatic organims; essential trace elements and immunological parameters in COVID/post-COVID patients

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

The Potential Roles of Natural Active Products in Neurological Disorders

edited by Anna D. Serefko

submission deadline 31 Oct 2024 | 3 articles | Viewed by 5796 | Submission Open

Keywords: natural active products; phytochemicals; bioactive compounds; Neurological Disorders; depressive disorders; Parkinson's disease; depressive/epileptic episodes; antidepressants and antiepileptics; Alzheimer's disease; brain stroke; molecular mechanism; drug delivery; therapeutic potentials; structure-activity relationships; advanced therapies

(This special issue belongs to the Section Bioactives and Nutraceuticals)

New Insights into Adipose Tissue Metabolic Function and Dysfunction, 3rd Edition

edited by

Federica Mannino

submission deadline 31 Oct 2024 | 5 articles | Viewed by 5519 | Submission Open

Keywords: inflammation; browning; thermogenesis; adipogenesis; diabetes; adipokines; energy storage; insulin resistance; obesity; lipolysis

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Non-coding RNA (ncRNA) in Cancer : 2nd Edition

edited by

Damjan Glavač

and

Metka Ravnik-Glavač

submission deadline 31 Oct 2024 | 3 articles | Viewed by 5345 | Submission Open

Keywords: non-coding RNA (ncRNA); cancer; oncogenes; tumor suppressor genes; microRNA; lncRNA; circRNA; cancer biomarkers

(This special issue belongs to the Section Molecular Oncology)

Molecular Aspects of Autoimmune Diseases

edited by Raquel López Mejías

submission deadline 31 Oct 2024 | 3 articles | Viewed by 5175 | Submission Open

Keywords: genetics; epigenetics; molecules; cellules; autoimmune diseases; inflammation

(This special issue belongs to the Section Molecular Immunology)

Heart Failure Mechanisms and Treatment Advances

edited by

Rabea Asleh

submission deadline 31 Oct 2024 | 3 articles | Viewed by 5138 | Submission Open

Keywords: heart failure; cardiomyopathy; mechanisms; inflammation; oxidative stress; genetic susceptibility; microbiome; neurohormonal regulation; obesity and metabolic syndrome; targeted therapies

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Oncolytic Viruses for Cancer Immunotherapy

edited by

Victor van Beusechem

submission deadline 31 Oct 2024 | 4 articles | Viewed by 5132 | Submission Open

Keywords: oncolytic viruses; anti-tumor immune responses; oncolytic immunotherapy

(This special issue belongs to the Section Molecular Oncology)

Recent Advances in Organic Chemistry: Molecules Synthesis and Reactions

edited by

José Justicia

and

Rachid Chahboun

submission deadline 31 Oct 2024 | 6 articles | Viewed by 4962 | Submission Open

Keywords: bioactive natural products; organocatalysis; photoredox reactions; free-radical reactions; organometallic reactions; organic synthesis

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Molecular Mechanisms and Novel Therapies of Liver Diseases

edited by

Mi Kyung Park

submission deadline 31 Oct 2024 | 3 articles | Viewed by 4900 | Submission Open

Keywords: acute and chronic liver diseases (CLDs); hepatocellular carcinoma (HCC); post-translational modification (PTM); autophagy; potential therapeutic approaches; preclinical mouse models

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Gene, Genomics, and Molecular Breeding in Cruciferae Plants (2nd Edition)

edited by

Maoteng Li

submission deadline 31 Oct 2024 | 8 articles | Viewed by 4839 | Submission Open

Keywords: Cruciferae plants; genome analysis; genetic dissection; gene function; molecular breeding

(This special issue belongs to the Section Molecular Plant Sciences)

Reprogramming the Tumor Microenvironment in Pancreatic Cancer

edited by

Mi Kyung Park

submission deadline 31 Oct 2024 | 2 articles | Viewed by 4750 | Submission Open

(This special issue belongs to the Section Molecular Oncology)

Integration of Meta-Multi-Omics Data: Unraveling Impact and Therapeutic Potential

edited by

Rui Vitorino

submission deadline 31 Oct 2024 | 3 articles | Viewed by 4561 | Submission Open

Keywords: integration meta-multiomics data; impact; aging; exercise; skeletal muscle; mitochondrial; heart; cancer; therapeutic; prevention; proteomics; omnibus; metabolite; metabolomic; repository dataset; public data

(This special issue belongs to the Section Molecular Informatics)

Prostate Cancer: Novel Research and Innovative Therapeutic Strategies

edited by

Giovanni Luca Beretta

submission deadline 31 Oct 2024 | 3 articles | Viewed by 4438 | Submission Open

Keywords: prostate cancer; therapeutic strategy; castration-resistant PCa

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Health Properties of Plant Bioactive Compounds: Immune, Antioxidant and Metabolic Effects 2.0

edited by

Antonio Carrillo-Vico

and

Ivan Cruz-Chamorro

submission deadline 31 Oct 2024 | 2 articles | Viewed by 4404 | Submission Open

Keywords: oxidative stress; inflammation; metabolism; plant bioactive compounds; functional food; nutraceuticals; natural extracts; human health; nutrition; metabolic syndrome; chronic diseases; cardiovascular diseases; cancer

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Biodegradable Polymer: Structure, Properties and Applications

edited by

Alexander Anatolyevich Yaroslavov

submission deadline 31 Oct 2024 | 3 articles | Viewed by 3952 | Submission Open

Keywords: biodegradable polymers; synthesis; structure; properties; applications

(This special issue belongs to the Section Materials Science)

Plant Pathogen Interactions: 2nd Edition

edited by

Jessie Fernandez

and

Sixue Chen

submission deadline 31 Oct 2024 | 3 articles | Viewed by 3897 | Submission Open

Keywords: pathogenicity; plant immunity; pattern-triggered immunity (PTI); effector-triggered immunity (ETI); effectors; avirulent; virulent; biotroph; necrotroph; interactions

(This special issue belongs to the Section Molecular Plant Sciences)

Nanotechnology in the Treatment and Diagnosis of Cancer: Opportunities and Challenges

edited by Lucyna Kapka-Skrzypczak

submission deadline 31 Oct 2024 | 3 articles | Viewed by 3814 | Submission Open

Keywords: nanomaterials; cancer; nanomedicine; biological effects; cancer therapy; metastasis

(This special issue belongs to the Section Molecular Nanoscience)

Nutritional and Hormonal Control of Glucose Metabolism

edited by

Joao Paulo Camporez

submission deadline 31 Oct 2024 | 2 articles | Viewed by 3702 | Submission Open

Keywords: glucose; lipids; amino acids; insulin resistance; obesity; NAFLD; hormones; metabolic syndrome; diabetes

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Genetics and Molecular Breeding of Cucurbitaceous Crops

edited by Younghoon Park

submission deadline 31 Oct 2024 | 5 articles | Viewed by 3686 | Submission Open

Keywords: Cucurbitaceae; melon; watermelon; cucumber; pumpkins; zucchini; gourd; evolution; genetic diversity; genetic resources; conventional breeding; molecular breeding; genomics-assisted breeding; precison breeding; genome editing; genome selection

(This special issue belongs to the Section Molecular Plant Sciences)

Skin Diseases: From Molecular Mechanisms to Pathology

edited by

Alessandro Terrinoni

submission deadline 31 Oct 2024 | 3 articles | Viewed by 3635 | Submission Open

Keywords: skin diseases; immunology; genetics

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Medical Imaging Technology in Molecular Pathological Mechanisms and Disease Therapies

edited by Howard J. Halpern

submission deadline 31 Oct 2024 | 2 articles | Viewed by 3461 | Submission Open

Keywords: medical imaging; fluorescent probe; molecular imaging；oxygen; redox; cancer therapy; resistance; electron paramagnetic resonance; imaging reconstruction; tumor/cancer microenvironment; pathological mechanisms; bioinformatics; genomics analysis; anti-cancer drug discovery; toxin delivery

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances in Research on Fruit Crop Breeding and Genetics: 3rd Edition

edited by

Pedro Martínez-Gómez

submission deadline 31 Oct 2024 | 4 articles | Viewed by 3366 | Submission Open

Keywords: fruit breeding; genetic; genomic; transcriptomic; proteomic; epigenetic

(This special issue belongs to the Section Molecular Plant Sciences)

Immunopathology, Vaccine Development and Treatment of Viruses

edited by Courtney B. Woolsey

submission deadline 31 Oct 2024 | 3 articles | Viewed by 3359 | Submission Open

Keywords: virus; immunopathology; vaccines; treatments; therapeutics; pathogenesis; molecular virology; emerging viruses

(This special issue belongs to the Section Molecular Immunology)

Atherosclerosis: From Molecular Basis to Therapy

edited by Massimiliano Ruscica

submission deadline 31 Oct 2024 | 2 articles | Viewed by 3192 | Submission Open

Keywords: atherosclerosis; molecular basis; cardiovascular disease; artery disease; vascular dementia

(This special issue belongs to the Section Molecular Biology)

Design and Application of Organic Superbases—from Theory to Experiment

edited by

Borislav Kovačević

submission deadline 31 Oct 2024 | 3 articles | Viewed by 3140 | Submission Open

Keywords: organic superbases; computational study; synthesis; structrue-function relationship; catalysis

(This special issue belongs to the Section Physical Chemistry and Chemical Physics)

Genetic Basis and Molecular Mechanisms of Heart Failure

edited by

Massimo Volpe

and

Giovanna Gallo

submission deadline 31 Oct 2024 | 1 articles | Viewed by 3118 | Submission Open

Keywords: heart failure; cardiomyopathies; genetics; molecular pathways; epigenetics; gene mutations

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Editorial Board Members’ Collection Series: “Molecular Dynamics”

edited by

Paulino Gómez-Puertas

and

James K. Bashkin

submission deadline 31 Oct 2024 | 2 articles | Viewed by 3108 | Submission Open

Keywords: quantum mechanics; classical mechanics; hybrid QM/MM; molecular dynamics at the atomic level; steered molecular dynamics; coarse-graining; docking(protein– protein; protein– ligand); the molecular dynamics of protein– ligand interactions; drug design; virtual screening

(This special issue belongs to the Section Molecular Biophysics)

RNA Function and Structure

edited by Anna Wacker

submission deadline 31 Oct 2024 | 1 articles | Viewed by 3035 | Submission Open

Keywords: RNA architecture; molecular motions; structural dynamics; NMR spectroscopy; RNA– RNA interaction; RNA-binding proteins; RNA– ligand complex; RNA recognition; RNA modifications; RNA targeting

(This special issue belongs to the Section Molecular Biology)

Immune Modulation of Macrophages: 2nd Edition

edited by

Paul Kwong Hang Tam

and Yan Chen

submission deadline 31 Oct 2024 | 3 articles | Viewed by 2949 | Submission Open

Keywords: macrophages; treatment; phenotype change; pathway analysis

(This special issue belongs to the Section Molecular Immunology)

Central and Local Modulators of Reproduction and Fertility: An Update (4th Edition)

edited by

Rosaria Meccariello

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2904 | Submission Open

Keywords: reproduction; fertility; HPG axis; testis; ovary; spermatogenesis; ovogenesis; gametes; GnRH; gonadotropins; sex steroids; kisspeptins; GnIH; metabolic sensors; leptin; endocannabinoids; autocrine/paracrine regulators; protein/peptide hormones; lipid mediators; epigenetics

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

New Advances in Protein Structure, Function and Design

edited by

Angelo Facchiano

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2880 | Submission Open

Keywords: AI applications in molecular structure; molecular simulations; new bioinformatics tools; protein structure; protein function; protein– protein interaction; online resources

(This special issue belongs to the Section Molecular Informatics)

Multiple Sclerosis at the Crossroads of Autoimmunity and Neurodegeneration 2.0

edited by

Serge Nataf

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2833 | Submission Open

Keywords: neurodegeneration; multiple sclerosis; autoimmunity; T lymphocytes; B lymphocytes; demyelination; axonal loss; synaptic pruning; microglia; astrocytes

(This special issue belongs to the Section Molecular Immunology)

The Lysosome in Human Health and Diseases

edited by

Maria Francisca Coutinho

Sandra Alves

and Marisa Encarnação

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2697 | Submission Open

Keywords: lysosomal storage disorders; lysosomal hub; lysosomal signalling; lysosomal trafficking; nutrient sensing; cell death; disease models; biomarkers; RNA-therapeutics

(This special issue belongs to the Section Molecular Biology)

Unravelling Interactions between Amyloid Beta (Aβ) and Key Pathological Features of Alzheimer’s Disease

edited by Athanasios Metaxas

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2641 | Submission Open

Keywords: Alzheimer’ s disease; amyloid; tau; neuroinflammation; synapses; metabolism

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Molecular Metabolism of Ameloblasts in Tooth Development

edited by Maiko Suzuki and Yong Hee Patricia Chun

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2603 | Submission Open

Keywords: ameloblasts; amelogenesis; metabolism; gene regulation; amelogenesis imperfecta; SCPP; enamel hypomineralization; tooth epithelial stem cells

(This special issue belongs to the Section Molecular Biology)

Spinocerebellar Ataxias: Uncovering Their Molecular Mechanisms, Biomarker Development, and Therapies

edited by Anna Sulek

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2283 | Submission Open

Keywords: spinocerebellar ataxia; biomarker; neurodegeneration; preclinical models; transcriptomics; proteomics; microRNA; iPSC; dynamic mutations

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Advances in Dry Eye Syndrome

edited by Maria Jesus Giráldez-Fernández and

Anxo Fernández Ferreiro

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2185 | Submission Open

Keywords: dry eye disease; tear film osmolarity; tear film; artificial tear substitutes; biological tear substitutes; tear fluid biomarkers; tear film lipid layer; meibomian gland dysfunction; evaporative dry eye; aqueous deficiency dry eye; ocular surface inflammation; cytokines; histological analysis; pharmacological treatment

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Wave of Cancer Therapeutics: Challenges and Opportunities

edited by

Moon Jong Kim

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2160 | Submission Open

Keywords: new therapeutic targets in cancers; advanced combination therapy strategies; advanced strategies for targeting cancer metabolism; advanced strategies for targeting the tumor microenvironment; antibody– drug conjugates (ADCs); biphasic antibody; PROTAC (proteolysis-targeting chimera); molecular glue; anti-sense oligonucleotides (ASOs)

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Strategies to Counteract Oxidative Stress and Inflammation in Chronic-Degenerative Diseases, 3rd Edition

edited by

Cecilia Prata

Cristina Angeloni

and

Tullia Maraldi

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2150 | Submission Open

Keywords: chronic-degenerative diseases; oxidative stress; inflammation; nutrition; nutraceuticals; stem cell therapy

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Displaying special issue 301-350 on page 7 of 70.

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