Diagnosis and Management of Pericardial Diseases

A special issue of Journal of Clinical Medicine (ISSN 2077-0383). This special issue belongs to the section "Cardiology".

Deadline for manuscript submissions: 25 October 2024 | Viewed by 522

Special Issue Editors


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Guest Editor
Cardiovascular And Thoracic Department, Città della Salute e della Scienza di Torino University Hospital, 10126 Torino, Italy
Interests: pericarditis; cardiovascular imaging; echocardiography; cardiac magnetic resonance; cardiovascular medicine; pericardial effusion

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Guest Editor
Cardiology, Cardiothoracic Department, and DAME, University of Udine, 33100 Udine, Italy
Interests: pericardial diseases; myocarditis; cardiomyopathies; heart failure; cardiac magnetic resonance; cardiac multimodality imaging; autoimmunity

Special Issue Information

Dear Colleagues,

Pericardial diseases, often referred to as the "Cinderella of heart disease", represent a challenging and contemporary issue for clinicians worldwide. Not only have we observed a constant rise in the number of cases in recent years, but patients are also showing increasing resistance to conventional treatments, especially after experiencing multiple pericarditis recurrences. The situation was exacerbated during the recent SARS-CoV-2 pandemic, with a significant upsurge in pericarditis cases, possibly linked to viral infections and, to a lesser extent, vaccination. This alarming trend has not only encouraged increased awareness but also ignited further research in this crucial clinical setting.

In the last few years, we have witnessed exciting developments, particularly with the advent of promising biological drugs, such as IL-1 inhibitors, which have been assessed in clinical studies. Additionally, researchers have delved into advanced diagnostic and prognostic assessments for pericardial diseases, enabling more precise and tailored patient care.

In light of these significant advancements, this Special Issue aims to gather and present the most recent breakthroughs in the diagnosis and management of pericardial diseases. Our goal is to equip clinicians with updated information that can be readily translated into their clinical practice, thus enhancing patient outcomes.

Dr. Alessandro Andreis
Prof. Dr. Massimo Imazio
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Journal of Clinical Medicine is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • pericarditis
  • pericardial effusion
  • multi-modality imaging
  • echocardiography
  • cardiac magnetic resonance
  • anakinra
  • rilonacept
  • anti IL-1
  • colchicine
  • constriction

Published Papers (1 paper)

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Review

15 pages, 988 KiB  
Review
Asymptomatic Chronic Large Pericardial Effusions: To Drain or to Observe?
by Emilia Lazarou, Charalambos Vlachopoulos, Alexios Antonopoulos, Massimo Imazio, Antonio Brucato, Costas Tsioufis and George Lazaros
J. Clin. Med. 2024, 13(13), 3887; https://doi.org/10.3390/jcm13133887 - 2 Jul 2024
Viewed by 279
Abstract
Pericardial effusions, especially large ones, have traditionally been regarded with concern by clinicians due to the sometimes unpredictable development of life-threatening cardiac tamponade. In the European Society of Cardiology Guidelines on pericardial diseases, the simplified algorithm for pericardial effusion triage and management recommends [...] Read more.
Pericardial effusions, especially large ones, have traditionally been regarded with concern by clinicians due to the sometimes unpredictable development of life-threatening cardiac tamponade. In the European Society of Cardiology Guidelines on pericardial diseases, the simplified algorithm for pericardial effusion triage and management recommends pericardial drainage in cases of cardiac tamponade and/or suspicion of bacterial or neoplastic etiology. In the presence of acute pericarditis, empiric anti-inflammatory treatment should be given, while when a specific indication known to be associated with pericardial effusion is found, then treatment of the underlying cause is indicated. Notably, the most challenging subgroup of patients includes those with large, asymptomatic, C-reactive-protein-negative, idiopathic effusions. In the latter subjects, pericardial drainage is proposed in cases of chronic effusions (lasting more than three months). However, this recommendation is based on scant data stemming from small-sized non-randomized studies. Nevertheless, recent evidence in a larger cohort of patients pointed out that a watchful waiting strategy is a safe option in terms of complication-free survival. This review summarizes the contemporary evidence on this challenging topic and provides recommendations for tailoring individual patient treatments. Full article
(This article belongs to the Special Issue Diagnosis and Management of Pericardial Diseases)
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