Small-Vessel Vasculitis

Dear Colleagues,

The etiology of small-vessel vasculitis remains enigmatic. The inflammation of small vessels can be seen in a range of diseases, most notably, of the autoimmune spectrum. Some are characterized by immune complex deposition such as systemic lupus erythematosus and some are the result of antibody-mediated autoimmunity such as anti-GBM disease and ANCA vasculitis. In the last thirty years, the pathophysiology of many vasculitides has become more comprehensible and treatment has steadily improved. Nevertheless, their etiology remains unknown and the risk of relapse with severe consequences remains.

The Special Issue entitled “Small-Vessel Vasculitis” of the Journal of Clinical Medicine is now open for submissions. This issue welcomes all types of papers on the clinical characteristics, prognosis, pathophysiology, and treatment of small-vessel vasculitides, including but not limited to IgA vasculitis, cryoglobulinemic vasculitis, anti-GBM disease, and ANCA-associated vasculitides. The goal of this Special Issue is to further enhance awareness of small-vessel vasculitis and boost the knowledge on its pathophysiology in order to generate new therapeutic options. An important topic we wish to address is the clinical and pathophysiological differences between subtypes of ANCA vasculitis, specifically between PR3-ANCA and MPO-ANCA.

Dr. Marc Hilhorst
Guest Editor

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