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  • Review
  • Open Access
157 Citations
59,808 Views
27 Pages

29 June 2023

Neuroimaging has revolutionized our understanding of brain function and has become an essential tool for researchers studying neurological disorders. Functional magnetic resonance imaging (fMRI) and electroencephalography (EEG) are two widely used ne...

  • Review
  • Open Access
63 Citations
49,880 Views
25 Pages

Artificial Intelligence and Healthcare: A Journey through History, Present Innovations, and Future Possibilities

  • Rahim Hirani,
  • Kaleb Noruzi,
  • Hassan Khuram,
  • Anum S. Hussaini,
  • Esewi Iyobosa Aifuwa,
  • Kencie E. Ely,
  • Joshua M. Lewis,
  • Ahmed E. Gabr,
  • Abbas Smiley and
  • Raj K. Tiwari
  • + 1 author

26 April 2024

Artificial intelligence (AI) has emerged as a powerful tool in healthcare significantly impacting practices from diagnostics to treatment delivery and patient management. This article examines the progress of AI in healthcare, starting from the field...

  • Review
  • Open Access
90 Citations
34,909 Views
16 Pages

Sepsis-Induced Coagulopathy: An Update on Pathophysiology, Biomarkers, and Current Guidelines

  • Andreas G. Tsantes,
  • Stavroula Parastatidou,
  • Emmanuel A. Tsantes,
  • Elli Bonova,
  • Konstantina A. Tsante,
  • Petros G. Mantzios,
  • Aristeidis G. Vaiopoulos,
  • Stavros Tsalas,
  • Aikaterini Konstantinidi and
  • Dimitra Houhoula
  • + 4 authors

28 January 2023

Significant cross talk occurs between inflammation and coagulation. Thus, coagulopathy is common in sepsis, potentially aggravating the prognosis. Initially, septic patients tend to exhibit a prothrombotic state through extrinsic pathway activation,...

  • Review
  • Open Access
31 Citations
32,782 Views
17 Pages

The Effect of Omega-3 Fatty Acids on Insulin Resistance

  • Susmita Sinha,
  • Mainul Haque,
  • Halyna Lugova and
  • Santosh Kumar

5 June 2023

Insulin resistance is a critical pathophysiological process in the onset and advancement of type 2 diabetes mellitus. It is well-recognized that alterations in the metabolism of lipids and aberrant fat buildup effectively trigger the development of r...

  • Article
  • Open Access
16 Citations
32,599 Views
12 Pages

14 October 2023

Background: Perceived psychological stress and exercise are bidirectionally related, and the effects of exercise on stress relief are well documented. However, research on the influence of stress on exercise remains scarce. This study examined the as...

  • Review
  • Open Access
112 Citations
29,917 Views
46 Pages

Short-Chain Fatty Acids and Human Health: From Metabolic Pathways to Current Therapeutic Implications

  • Sonia Facchin,
  • Luisa Bertin,
  • Erica Bonazzi,
  • Greta Lorenzon,
  • Caterina De Barba,
  • Brigida Barberio,
  • Fabiana Zingone,
  • Daria Maniero,
  • Marco Scarpa and
  • Cesare Ruffolo
  • + 2 authors

26 April 2024

The gastrointestinal tract is home to trillions of diverse microorganisms collectively known as the gut microbiota, which play a pivotal role in breaking down undigested foods, such as dietary fibers. Through the fermentation of these food components...

  • Review
  • Open Access
12 Citations
29,583 Views
19 Pages

Therapeutic Effects of Cannabinoids and Their Applications in COVID-19 Treatment

  • Rebeca Pérez,
  • Talita Glaser,
  • Cecilia Villegas,
  • Viviana Burgos,
  • Henning Ulrich and
  • Cristian Paz

15 December 2022

Cannabis sativa is one of the first medicinal plants used by humans. Its medical use remains controversial because it is a psychotropic drug whose use has been banned. Recently, however, some countries have approved its use, including for recreationa...

  • Review
  • Open Access
16 Citations
27,957 Views
15 Pages

Sucralose: From Sweet Success to Metabolic Controversies—Unraveling the Global Health Implications of a Pervasive Non-Caloric Artificial Sweetener

  • José Alfredo Aguayo-Guerrero,
  • Lucía Angélica Méndez-García,
  • Helena Solleiro-Villavicencio,
  • Rebeca Viurcos-Sanabria and
  • Galileo Escobedo

29 February 2024

Sucralose is a food additive initially used to mitigate glycemic peaks and calorie intake in patients with diabetes and obesity. Although sucralose has been considered safe for human consumption, the World Health Organization (WHO) issued a global al...

  • Review
  • Open Access
125 Citations
27,522 Views
37 Pages

7 February 2024

Drug development is expensive, time-consuming, and has a high failure rate. In recent years, artificial intelligence (AI) has emerged as a transformative tool in drug discovery, offering innovative solutions to complex challenges in the pharmaceutica...

  • Review
  • Open Access
17 Citations
26,828 Views
11 Pages

Warfarin and Antibiotics: Drug Interactions and Clinical Considerations

  • Alexis J. Vega,
  • Caitlin Smith,
  • Hannah Grace Matejowsky,
  • Katherine J. Thornhill,
  • Grant E. Borne,
  • Chizoba N. Mosieri,
  • Sahar Shekoohi,
  • Elyse M. Cornett and
  • Alan D. Kaye

30 July 2023

Warfarin administration poses a notable challenge in clinical practice due to the increased susceptibility of patients to major bleeding, particularly when co-administered with other medications capable of modulating its metabolic pathways. Among the...