Antioxidants—Key Players in Innovative Pharmaceutical Products and Food Supplements
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Pharmaceutical Science".
Deadline for manuscript submissions: 31 January 2025 | Viewed by 680
Special Issue Editors
Interests: biochemistry of free radicals; antioxidants; nutritional supplements; oxidative stress in pathological conditions
Interests: natural product chemistry; pharmacology; biomarkers; antioxidants; oxidative stress; microbiology
Interests: nutrition; food safety; food technology; biotechnology; pharmaceutical research and development; dosage form development; pharmaceutical analysis; clinical biochemistry
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Since the late 1970s, when the term "oxidative stress" was coined by Helmut Sies, we have witnessed the growth of a field revolving around free radicals and antioxidants. Free radicals play a pivotal role in aging and various diseases like cancer, diabetes, and neurodegenerative disorders. Therefore, antioxidants have garnered attention as potential prophylactic and therapeutic agents. However, antioxidants’ delivery through conventional dosage forms, e.g., tablets, capsules, dragées etc has some shortcomings. Issues such as high lipophilicity, instability, and extensive first-pass metabolism limit their bioavailability. Innovative drug delivery systems offer a solution, enhancing bioavailability and targeting specific tissues. Apart from their use as active substances, antioxidants have attracted attention as technical compounds that potentially limit nitrosamine formation and oxidative modifications in pharmaceuticals and food supplements.
This Special Issue of Life focuses on recent theoretical and experimental advancements in antioxidant delivery methods and the application of antioxidants as technical compounds.
Dr. Bogdan Manolescu
Dr. Eliza Oprea
Dr. Magdalena Mititelu
Guest Editors
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Keywords
- antioxidants
- delivery systems
- controlled release
- bioavailability
- bioactive natural products
- food supplements
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