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Life publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Prognosis and Management of Dry Eye Disease

edited by

Hugo Pena-Verdeal

Alena Furdova

and

Jacobo Garcia-Queiruga

submission deadline 31 Dec 2024 | 1 articles | Viewed by 1493 | Submission Open

Keywords: dry eye disease; dry eye epidemiology; dry eye management; dry eye natural course; meibomian gland dysfunction; evaporative dry eye; aqueous deficiency dry eye; artificial tear substitutes; tear film lipid layer; meibomian glands

(This special issue belongs to the Section Medical Research)

Recent Advances in Shockwave Therapy for Musculoskeletal and Soft-Tissue Disorders

edited by

Marco Gesi

Mario Vetrano

, Maria Chiara Vulpiani, Maria Cristina D'Agostino, Larisa Ryskalin and Federica Fulceri

submission deadline 31 Dec 2024 | 1 articles | Viewed by 1418 | Submission Open

Keywords: shockwave; tissue regeneration; pain; functional recovery and healing; physical medicine and rehabilitation; clinical applications; imaging

(This special issue belongs to the Section Medical Research)

The Treatments for Cardiovascular Diseases

edited by

Carlos A. C. Dias Junior

submission deadline 31 Dec 2024 | 1 articles | Viewed by 945 | Submission Open

Keywords: nitric oxide; hydrogen sulfide; reactive oxygen species; angiotensin; endothelin

(This special issue belongs to the Section Medical Research)

Personalized Medicine in Ophthalmic Diseases: Updated Challenges and Opportunities

edited by

Camelia Margareta Bogdanici

submission deadline 31 Dec 2024 | 1 articles | Viewed by 819 | Submission Open

Keywords: vision-related quality of life; personalized medicine; artificial intelligence; ophthalmology and nutrition; optical coherence tomography; ocular surface diseases; retinal vascular diseases

(This special issue belongs to the Section Medical Research)

Advances in Diagnosis and Management of Peyronie’s Diseases

edited by

Lucio Dell'Atti

submission deadline 31 Dec 2024 | 1 articles | Viewed by 636 | Submission Open

Keywords: Peyronie’ s disease; fibrotic degeneration; penis trauma

(This special issue belongs to the Section Medical Research)

Current Progress in Medical Image Segmentation

edited by

Krishna Chaitanya

submission deadline 31 Dec 2024 | Viewed by 405 | Submission Open

Keywords: medical image segmentation; deep learning; generative models; algorithm; clinical integration; biological variability; transformer architectures; interactive segmentation; interdisciplinary collaboration

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Bioinformatics Tools and Machine Learning Methods for Biomarker Discovery

edited by

Trang Do

and

Binh P. Nguyen

submission deadline 31 Dec 2024 | Viewed by 333 | Submission Open

Keywords: bioinformatics; machine learning; deep learning; biomarkers; multi-omics; NGS; single-cell; gene expression

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Advances in Integrative Omics Data Analysis for Cancer Research

edited by

Jian Sang

, Jianli Dai and Guangyi Niu

submission deadline 31 Dec 2024 | Viewed by 327 | Submission Open

Keywords: cancer research; omics; bioinformatics; translational medicine

(This special issue belongs to the Section Genetics and Genomics)

Genetic Insights Into Liver Diseases

edited by Monica Mischitelli and

Flaminia Ferri

submission deadline 31 Dec 2024 | Viewed by 276 | Submission Open

Keywords: liver genetics; liver disease progression; personalized medicine; genetic risk score

(This special issue belongs to the Section Genetics and Genomics)

Long-Term Dynamics of Biodiversity in Aquatic Environments

edited by Emilie Saulnier-Talbot

submission deadline 31 Dec 2024 | Viewed by 268 | Submission Open

Keywords: paleolimnology; paleoceanography; global change; anthropogenic pressure; extirpation; extinction; functional diversity; α diversity; β diversity; species distribution

(This special issue belongs to the Section Diversity and Ecology)

Innovative Applications of Extracellular Vesicles: From Diagnostics to Drug Delivery

edited by Alessandra Lo Cicero

submission deadline 31 Dec 2024 | Viewed by 225 | Submission Open

Keywords: extracellular vesicles; exosomes; cancer; cardiovascular diseases; neurodegenerative diseases; biomarkers; diagnostics; cell-cell communication; drug delivery; therapeutics

(This special issue belongs to the Section Physiology and Pathology)

Recent Advances in Medical Imaging and Machine Learning

edited by Ester Bonmati Coll and Barbara Villarini

submission deadline 31 Dec 2024 | Viewed by 201 | Submission Open

Keywords: image pattern recognition; image classification; image segmentation; diagnosis; anomaly detection; genetics with medical imaging; machine learning; deep learning; research translation

(This special issue belongs to the Section Medical Research)

Precision Medicine in Cardiovascular Diseases

edited by Brian Xiangzhi Wang

submission deadline 31 Dec 2024 | Viewed by 182 | Submission Open

Keywords: genomic; cardiovascular disease; congenital; multi-omics studies; precision medicine; personalized medicine; biomarker

(This special issue belongs to the Section Genetics and Genomics)

Revolutionizing Neuroregeneration

edited by

Kiminobu Sugaya

submission deadline 31 Dec 2024 | Viewed by 181 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; neuroregeneration; stroke; regenerative therapy

(This special issue belongs to the Section Cell Biology and Tissue Engineering)

Infection, Colonization, and Spread of Drug-Resistant Bacteria

edited by Jialing Lin

submission deadline 31 Dec 2024 | Viewed by 177 | Submission Open

Keywords: antibiotic resistance; bacterial infection; bacterial colonization; bacterial spread; hospital-acquired infections; community-acquired infections

(This special issue belongs to the Section Microbiology)

Clinical and Laboratory Advancements and Challenges in Medically Assisted Reproduction

edited by

Alessandra Alteri

and Valeria Stella Vanni

submission deadline 31 Dec 2024 | Viewed by 170 | Submission Open

Keywords: medically assisted reproduction; assisted reproduction technologies; clinical embryology; genetic testing; ovarian stimulation; male factor; endometriosis; endometrial receptivity; implantation

(This special issue belongs to the Section Reproductive and Developmental Biology)

Diabetes and Microbiome

edited by

Gratiela Pircalabioru

and Octavian Savu

submission deadline 31 Dec 2024 | Viewed by 144 | Submission Open

Keywords: diabetes mellitus; microbiome; microbiota metabolites; metabolic disease; dysbiosis

(This special issue belongs to the Section Microbiology)

Skin Cancer: From Molecular Basis to Therapy: 2nd Edition

edited by

Alvise Sernicola

submission deadline 31 Dec 2024 | Viewed by 127 | Submission Open

Keywords: nonmelanoma skin cancer; melanoma; cutaneous lymphoma; Kaposi sarcoma; skin-directed therapy; carcinogenesis; UV radiation; tumor predisposition syndrome

(This special issue belongs to the Section Medical Research)

Advances in the Interventional Cardiology

edited by Luigi Cappannoli, Domenico Galante and

João Morais

submission deadline 31 Dec 2024 | Viewed by 123 | Submission Open

Keywords: ischemic heart disease; valvular heart disease; heart failure; percutaneous coronary; intervention; structural heart intervention; mechanical circulatory support; devices

(This special issue belongs to the Section Medical Research)

Back to Basics in Palaeontology

edited by Hua Stephane

submission deadline 8 Jan 2025 | 3 articles | Viewed by 5065 | Submission Open

Keywords: fundamentals; natural history; multidisciplinarity; first hand bibliography; actualism

(This special issue belongs to the Section Paleobiology)

Elements Cycling and Plants’ Physiological Characteristics: A Soil–Plant–Atmosphere Continuum Perspective

edited by

Ling Zhang

and

Zhi Li

submission deadline 15 Jan 2025 | 3 articles | Viewed by 3867 | Submission Open

Keywords: element cycling; microbial communities; plant nutrition; plant physiology; plant biochemistry; atmospheric composition; climate change; soil– plant– atmosphere interaction; plant– soil feedback

(This special issue belongs to the Section Diversity and Ecology)

Advances in Neuroimaging and Functional Brain Analysis

edited by Gianvincenzo Sparacia

submission deadline 15 Jan 2025 | Viewed by 419 | Submission Open

Keywords: magnetic resonance imaging; resting-state functional magnetic resonance imaging; connectomics; functional connectivity; brain networks; brain diseases assessment

(This special issue belongs to the Section Medical Research)

Advances in Endoscopy for Hepatic, Pancreatic, and Biliary Diseases

edited by John Ong

submission deadline 16 Jan 2025 | Viewed by 167 | Submission Open

Keywords: endoscopic intervention; endoscopic ultrasound; lumen apposing metal stent; radiofrequency ablation; endoscopic sleeve gastroplasty; cholangioscopy; endoscopic retrograde cholangiopancreatography; liver disease; biliary disease; pancreatobiliary disease

(This special issue belongs to the Section Medical Research)

New Insights Into Artificial Intelligence in Medical Imaging

edited by

Luigi La Via

Antonino Maniaci

Caterina Gagliano

and Salvatore Lavalle

submission deadline 17 Jan 2025 | 2 articles | Viewed by 2283 | Submission Open

Keywords: artificial intelligence; machine learning; deep learning; image analysis; precision medicine; image-guided interventions; decision support systems

(This special issue belongs to the Section Radiobiology and Nuclear Medicine)

Research Progress of Cultivation of Edible Fungi

edited by Yajie Zou

submission deadline 20 Jan 2025 | 5 articles | Viewed by 6815 | Submission Open

Keywords: edible fungi; cultivation; domesticate; substrate; biological efficiency; nutritional properties; functional compounds; sustainability; commercialization; emerging species

(This special issue belongs to the Section Microbiology)

Advancements in Veterinary Oncology

edited by

José Pimenta

Mário Pedro Goncalves Cotovio

Justina Prada

and

Isabel Pires

submission deadline 20 Jan 2025 | Viewed by 618 | Submission Open

Keywords: veterinary and comparative oncology; epidemiology; tumor biology; diagnosis; treatment; biomarkers

(This special issue belongs to the Section Animal Science)

Microbiota in Health and Disease

edited by Amélia Sarmento and

Catarina Simões

submission deadline 21 Jan 2025 | 7 articles | Viewed by 10433 | Submission Open

Keywords: microbiota; microbiome; dysbiosis; diet; metabolism; immune regulation

(This special issue belongs to the Section Microbiology)

Development and Application of Antimicrobials

edited by

Virginia Fuochi

Pio Maria Furneri

and Adriana Garozzo

submission deadline 21 Jan 2025 | 1 articles | Viewed by 1241 | Submission Open

Keywords: antiviral activity; antimicrobial activity; probiotics; bacteriocins; essential oils; natural extracts; drug delivery systems; drug development

(This special issue belongs to the Section Microbiology)

Optical Imaging and Fluorescence Imaging in Breast Cancer Diagnosis and Surgery

edited by

Muriel Abbaci

Angelica Conversano

and Sanjay Warrier

submission deadline 22 Jan 2025 | 3 articles | Viewed by 6826 | Submission Open

Keywords: optical imaging; fluorescence imaging; breast cancer surgery; breast cancer diagnosis; breast reconstructive surgery; microscopy; breast tumor; lymph node; fluorophore

(This special issue belongs to the Section Medical Research)

Metabolic Health: The Interplay between NAFLD, MAFLD, MASLD and Cardiovascular Disease

edited by

Marcin Kosmalski

and Monika Różycka-Kosmalska

submission deadline 26 Jan 2025 | 2 articles | Viewed by 1248 | Submission Open

Keywords: non-alcoholic fatty liver disease (NAFLD); metabolic-dysfunction-associated fatty liver disease (MAFLD); metabolic-dysfunction-associated steatotic liver disease (MASLD); cardiovascular disease (CVD); cardiac arrhythmias; structural heart disease; coronary artery disease; hypertension

(This special issue belongs to the Section Medical Research)

Applications of Molecular Dynamics to Biological Systems

edited by

Ron Elber

submission deadline 28 Jan 2025 | Viewed by 87 | Submission Open

Keywords: computer simulation; biophysical modeling; molecular dynamics

(This special issue belongs to the Section Biochemistry, Biophysics and Computational Biology)

Retinal Diseases: From Molecular Mechanisms to Therapeutics

edited by

Soo-Young Kim

submission deadline 30 Jan 2025 | 5 articles | Viewed by 6776 | Submission Open

Keywords: retinal disease; inflammatory disease; genetic diseases; ocular drug development

(This special issue belongs to the Section Physiology and Pathology)

Advanced Strategies in Fracture Treatments

edited by

Kai-Cheng Lin

and Chun-Yu Chen

submission deadline 30 Jan 2025 | 6 articles | Viewed by 4956 | Submission Open

Keywords: state of the art; peri-articular fracture; osteoporotic fracture; fragility fracture; treatment protocols

(This special issue belongs to the Section Medical Research)

Pathogenic Mechanisms, Diagnosis, and Treatment of Hypertension: Insights and Implications

edited by Shengyu Mu and Sankar Devarajan

submission deadline 30 Jan 2025 | 2 articles | Viewed by 2118 | Submission Open

Keywords: hypertension; cardiovascular disease; blood pressure; pathogenesis

(This special issue belongs to the Section Physiology and Pathology)

Acari: Biodiversity, Biogeography and Taxonomy Studies

edited by Pavel B. Klimov

submission deadline 30 Jan 2025 | Viewed by 317 | Submission Open

Keywords: phylogenetics; systematics; evolution and co-evolution; biodiversity; ecology; host associations; role of mites in agriculture and medicine

(This special issue belongs to the Section Animal Science)

Bone Cancer: From Molecular Mechanism to Treatment

edited by

Chih-Yang Lin

and Syuan-Ling Lin

submission deadline 30 Jan 2025 | Viewed by 104 | Submission Open

Keywords: bone cancer; metastasis; angiogenesis; targeted drugs; biomarkers

(This special issue belongs to the Section Medical Research)

Advances in Novel Biomaterials-Based Fertilizing Products and Bio-Fertilizers for Sustainable Agricultural Production

edited by

and

submission deadline 31 Jan 2025 | 8 articles | Viewed by 16609 | Submission Open

Keywords: biomaterials and bio-nanomaterials; bio-based hydrogels and polymers; lignocellulosic biomass and its derivatives; sustainable agriculture; biodegradability; stimuli-responsive fertilizer delivery; controlled-release fertilizers; bio-synthesis processes and characterization; control/sustained fertilizer release mechanisms; biofertilizers; plant growth-promoting microbes; fertilizers’ use efficiency; plant physiology; productivity; and quality

(This special issue belongs to the Section Plant Science)

Advances and Applications of Sport Physiology

edited by

Sime Versic

and

Nikola Foretic

submission deadline 31 Jan 2025 | 5 articles | Viewed by 8806 | Submission Open

Keywords: sports medicine; strength and conditioning; diagnostics; sport injuries; performance analysis

(This special issue belongs to the Section Physiology and Pathology)

Feature Paper in Physiology and Pathology: 2nd Edition

edited by

Stefanos Roumeliotis

and Eleni Stamellou

submission deadline 31 Jan 2025 | 7 articles | Viewed by 4751 | Submission Open

Keywords: applied physiology; biomechanics; cardiovascular pathobiology; cell physiology; comparative pathology; comparative physiology

(This special issue belongs to the Section Physiology and Pathology)

New Trends in Otorhinolaryngology

edited by

Arianna Di Stadio

Massimo Ralli

and

Pietro De Luca

submission deadline 31 Jan 2025 | 4 articles | Viewed by 4417 | Submission Open

Keywords: head and neck; otolaryngology; hearing loss; speech disorders; swallowing disorders; cancer; microRNA; nose; plastic surgery

(This special issue belongs to the Section Medical Research)

Advancements in Heart Failure Research

edited by Tzu-Hurng Cheng and

Ju-Chi Liu

submission deadline 31 Jan 2025 | 2 articles | Viewed by 3196 | Submission Open

Keywords: cardiac remodeling; biomarkers; precision medicine; patient-centered care; therapeutic innovations

(This special issue belongs to the Section Medical Research)

Interaction Between Dietary Components and Gut Microbiota: Their Effect on Human and Animal Health

edited by

Georgia Saxami

Dimitrios Arapoglou

and

Christos Eliopoulos

submission deadline 31 Jan 2025 | 2 articles | Viewed by 2475 | Submission Open

Keywords: gut microbiota; dietary components; disease prevention and development; probiotic and prebiotic; omics approaches; animals’ gut health

(This special issue belongs to the Section Microbiology)

Feature Papers in Medical Research: 3rd Edition

edited by

Christian Lehmann

submission deadline 31 Jan 2025 | 2 articles | Viewed by 1986 | Submission Open

Keywords: dermatological research; cancer research; cardiovascular research; general medicine; gastroenterological research; hematological research; immunological research; infectious diseases research; metabolism and endocrinology; nervous system research; nursing; pediatrics; pulmonary research; psychiatric research; rehabilitation; renal and urinary research; reproductive research and women's health; rheumatological research; skeletal and muscular research; vision research

(This special issue belongs to the Section Medical Research)

Plant Functional Genomics and Breeding

edited by

Yifeng Wang

submission deadline 31 Jan 2025 | 3 articles | Viewed by 1862 | Submission Open

Keywords: functional genomics; biological breeding; gene cloning; molecular network; genetic improvement

(This special issue belongs to the Section Plant Science)

Novel Finding in Cancer Genomics

edited by

Da-Tian Bau

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1620 | Submission Open

Keywords: bladder cancer; prostate cancer; renal cell carcinoma; upper tract urothelial carcinoma

(This special issue belongs to the Section Genetics and Genomics)

Pancreatic Cancer Long Survivals

edited by Francesco Leonardi and

Ingrid Garajova

submission deadline 31 Jan 2025 | 1 articles | Viewed by 1402 | Submission Open

Keywords: pancreatic cancer; long survival; outcome; pancreatic adenocarcinoma; long-term survival; surgical resection; chemotherapy; NGS

(This special issue belongs to the Section Physiology and Pathology)

Resistance Training Is Medicine

edited by

Daniel J. McDonough

submission deadline 31 Jan 2025 | 1 articles | Viewed by 799 | Submission Open

Keywords: resistance training; resistance exercise; physical activity; sedentary behavior; strength training; chronic disease; risk factors; obesity; physical health

(This special issue belongs to the Section Epidemiology)

Antioxidants—Key Players in Innovative Pharmaceutical Products and Food Supplements

edited by Bogdan Manolescu, Eliza Oprea and

Magdalena Mititelu

submission deadline 31 Jan 2025 | Viewed by 705 | Submission Open

Keywords: antioxidants; delivery systems; controlled release; bioavailability; bioactive natural products; food supplements

(This special issue belongs to the Section Pharmaceutical Science)

Common and Novel Markers of Inflammation and Tissue Damage in Various Pathological Conditions

edited by

Marzena Tylicka

Joanna Kamińska

and

Olga Koper-Lenkiewicz

submission deadline 31 Jan 2025 | 1 articles | Viewed by 695 | Submission Open

Keywords: body fluids; cytokines; damage-associated molecular patterns (DAMPS); inflammatory response; injury; markers of inflammation and tissue damage; metalloproteinases; novel markers; pathological conditions; proteasome; tissue damage; tissue repair processes; various diseases

(This special issue belongs to the Section Physiology and Pathology)

Cardioncology: From Molecular Mechanisms to Advanced Imaging and New Treatments

edited by

Carla Contaldi

, Giuseppe Pacileo and

Paolo Calabrò

submission deadline 31 Jan 2025 | Viewed by 343 | Submission Open

Keywords: cardiotoxicity; echocardiography; cardiac magnetic resonance; cardiac computed tomography; serum cardiac biomarkers; cancer therapy; arrhythmias; cardiotoxicity treatment

(This special issue belongs to the Section Physiology and Pathology)

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