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Metabolites publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Metabolic Syndrome and Non-alcoholic Liver Disease

edited by

Mircea-Catalin Fortofoiu

and

Luigi Boccuto

submission deadline 20 Oct 2024 | 3 articles | Viewed by 4204 | Submission Open

Keywords: metabolic syndrome; non-alcoholic fatty liver disease (NAFLD); insulin resistance; obesity; type 2 diabetes; liver cirrhosis; dyslipidemia; NAFLD treatment; hepatic steatosis; cardiovascular risk

(This special issue belongs to the Section Lipid Metabolism)

Method Development in Metabolomics and Exposomics

edited by Facundo M. Fernandez

submission deadline 20 Oct 2024 | Viewed by 160 | Submission Open

Keywords: metabolomics; exposomics; lipidomics; metabolite; environmental exposure

(This special issue belongs to the Section Bioinformatics and Data Analysis)

Mass Spectrometry-Based Metabolomics in Health and Disease: Targeted Analysis

edited by Emanuele Porru

submission deadline 25 Oct 2024 | 1 articles | Viewed by 890 | Submission Open

Keywords: mass spectrometry; metabolomics; metabolic diseases; chromatography; biomarkers

(This special issue belongs to the Section Advances in Metabolomics)

Multimodal Approaches to Diagnosing Metabolic Bone Diseases

edited by Simona D’Amore,

Antonio G. Solimando

and Uma Ramaswami

submission deadline 30 Oct 2024 | Viewed by 283 | Submission Open

Keywords: bone disease; bone involvement in congenital and acquired conditions; artificial intelligence; bi-omarker discovery; clinical algorithm; integrated imaging approaches; omics-based approaches

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Metabolites in Ruminant Health

edited by

Diming Wang

submission deadline 31 Oct 2024 | 7 articles | Viewed by 10979 | Submission Open

Keywords: ruminants; health; metabolites

(This special issue belongs to the Section Animal Metabolism)

Identification and Therapeutic Properties of Secondary Metabolites of Medicinal Plants II

edited by

Marijana Zovko Končić

and

Michał Tomczyk

submission deadline 31 Oct 2024 | 3 articles | Viewed by 6238 | Submission Open

Keywords: antioxidant activity; bioactivity; chromatography; phytochemistry; phytotherapy; plant secondary metabolites; polyphenols

(This special issue belongs to the Section Plant Metabolism)

New Advancements and Challenges in Clinical Metabolomics for Inborn Errors of Metabolism and Rare Diseases

edited by Adam D. Kennedy and

Sarah H. Elsea

submission deadline 31 Oct 2024 | 4 articles | Viewed by 4888 | Submission Open

Keywords: metabolic diseases; rare diseases; clinical metabolomics; genomics; inborn errors of metabolism

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Mitochondrial Metabolism and Oxidative Stress in Hypertension, Diabetes and Related Complications

edited by

Christian Cortés-Rojo

submission deadline 31 Oct 2024 | 2 articles | Viewed by 2241 | Submission Open

Keywords: diabetes; hypertension; ROS; oxidative stress; cell death; inflammation; mitochondrial control quality; mitochondrial dynamics; mitochondria-targeted molecules; nutraceuticals and functional foods

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Proteomic and Metabolomic Analyses of Fisheries and Aquaculture

edited by

Denise Schrama

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2086 | Submission Open

Keywords: proteomics; metabolomics; aquaculture; fisheries; fish nutrition; fish welfare; fish pathology

(This special issue belongs to the Section Nutrition and Metabolism)

Lipid Metabolism in Obesity and Diabetes, 2nd Edition

edited by

Hajnalka Lőrincz

and

Mariann Harangi

submission deadline 31 Oct 2024 | 1 articles | Viewed by 2075 | Submission Open

Keywords: lipoprotein; lipid metabolism; dyslipidemia; atherosclerosis; obesity; insulin resistance; diabetes; adipokine; hepatokine; oxidative stress; vascular senescence; lipid-lowering treatment; antidiabetic drugs

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Advances in Ecotoxicology and Metabolism

edited by Chan Xiong

submission deadline 31 Oct 2024 | 1 articles | Viewed by 716 | Submission Open

Keywords: environmental pollutants; mass spectrometry; biological systems; metallomics; heavy metal metabolism; biochemical pathways; gut microbiota metabolites; environmental metabolites; ecosystem integrity

(This special issue belongs to the Section Environmental Metabolomics)

Insights into Tumor Cell Metabolism and Epigenetics

edited by

Sara Granja

, Vera Miranda-Gonçalves and Filipa Vieira

submission deadline 31 Oct 2024 | Viewed by 332 | Submission Open

Keywords: Warburg effect; epigenetic alterations; metabolic reprogramming; epigenome; transcriptional regula-tion; fatty acid metabolism

(This special issue belongs to the Section Cell Metabolism)

Glucose Metabolism in Cardiovascular Diseases

edited by Hidenori Komiyama and

Kuniya Asai

submission deadline 31 Oct 2024 | Viewed by 185 | Submission Open

Keywords: glucose metabolism; insulin resistance; statin use; mitochondrial function; heart failure; IoT devices; daily activity; skeletal muscle

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Emerging Applications of Urinary Metabolomics in Cancer

edited by

Casey Burton

submission deadline 11 Nov 2024 | 1 articles | Viewed by 833 | Submission Open

Keywords: urinary metabolomics; cancer biomarkers; early cancer detection; analytical method development; therapeutic response monitoring

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Impact of Macronutrients on Metabolism

edited by Janine Wirth

submission deadline 15 Nov 2024 | 6 articles | Viewed by 36990 | Submission Open

Keywords: carbohydrate intake; dietary protein; chronic metabolic response

(This special issue belongs to the Section Nutrition and Metabolism)

Machine Learning in Metabolic Diseases

edited by

Rui Wang-Sattler

submission deadline 15 Nov 2024 | 3 articles | Viewed by 5770 | Submission Open

Keywords: machine learning; supervised; unsupervised; model selection; training and testing; data pre-processing; prediction; identification; validation risk factors/biomarkers; metabolic disease

(This special issue belongs to the Section Bioinformatics and Data Analysis)

Research Progress of Plant Compounds for Diabetes and Its Complications, 2nd Edition

edited by

Cosmin Mihai Vesa

and

Dana Zaha

submission deadline 15 Nov 2024 | Viewed by 744 | Submission Open

Keywords: plant compounds; plant extracts; plant supplement metabolites; diabetes mellitus type 2; diabetic retinopathy; diabetes complications

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Metabolomic Advances in Promoting Exercise-Induced Metabolic Changes

edited by

Alex Castro

and Mara Patrıcia Traina Chacon-Mikahi

submission deadline 20 Nov 2024 | 7 articles | Viewed by 11092 | Submission Open

Keywords: metabolome; metabolites; exercise; physical activity; metabolic signatures

(This special issue belongs to the Section Advances in Metabolomics)

Advances in Understanding the Impact of Pregnancy in Inherited Metabolic Disorders

edited by

Gisela Wilcox

submission deadline 20 Nov 2024 | 1 articles | Viewed by 4794 | Submission Open

Keywords: pregnancy; inborn errors of metabolism; inherited metabolic disorders; urea cycle disorders; mitochondrial function; foeto-maternal medicine; fatty acid oxidation; amino acid disorders; phenylketonuria; glycogen storage diseases; lysosomal storage disorders; lactation; postpartum

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

The Multifaceted Roles of Biomarkers in Metabolic Disorders: From Diagnosis and Monitoring to Prediction, Management, and Treatment

edited by

Prince Dadson

and

Miikka-Juhani Honka

submission deadline 26 Nov 2024 | Viewed by 231 | Submission Open

Keywords: metabolism; dysmetabolism; tissue-specific metabolism; cardiometabolic disorders; nutritional dis-orders; functional biomarkers; metabolomics profiling; multi-omics data integration; biochemical pathways; personalized medicine

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Plants and Plant-Based Foods for Metabolic Disease Prevention

edited by

Sandra Barbalho

, Rosa Direito,

Adriano Araujo

and

Élen Landgraf Guiguer

submission deadline 27 Nov 2024 | 2 articles | Viewed by 941 | Submission Open

Keywords: plants; plant foods; plant-based diet; medicinal plants; inflammation; oxidative stress; inflammatory diseases; metabolic diseases; neurodegenerative diseases

(This special issue belongs to the Section Nutrition and Metabolism)

Lipidomics as a Diagnostic Tool: Lipid Metabolism and Its Related Human Diseases

edited by Kristal M. Maner-Smith and Arion J. Kennedy

submission deadline 29 Nov 2024 | 1 articles | Viewed by 3391 | Submission Open

Keywords: lipidomics; metabolomics; nutrition; bioactive lipids; signaling lipids; polyunsaturated fatty acids; oxylipins; endocannabinoids; sphingolipids; ceramides

(This special issue belongs to the Section Lipid Metabolism)

Nutrient Metabolism and Intestinal Health Studies in Aquatic Animals

edited by

Gang Yang

Vikas Kumar

and

Songlin Li

submission deadline 30 Nov 2024 | 7 articles | Viewed by 14691 | Submission Open

Keywords: aquatic animal nutrition; gut– liver axis; intestinal microbiome; inflammation; immunity; physiology; feed additive; plant extracts; probiotics

(This special issue belongs to the Section Animal Metabolism)

Cellular Metabolism in Neurological Disorders

edited by

Wenting Guo

Laura Fumagalli

and

Teodoro Bottiglieri

submission deadline 30 Nov 2024 | 4 articles | Viewed by 9344 | Submission Open

Keywords: metabolism ; neurodegeneration ; mitochondria ; glycogen; therapeutic targets; neurons; glia

(This special issue belongs to the Section Cell Metabolism)

Muscle Metabolic Response and Adaptation to Exercise, Diet, and Environment

edited by

Susumu Muroya

submission deadline 30 Nov 2024 | 2 articles | Viewed by 5269 | Submission Open

Keywords: skeletal muscle; metabolomics; mitochondria; energy metabolism; lipid metabolism; nutrition; feeding; environment; exercise; stress

(This special issue belongs to the Section Animal Metabolism)

Metabolomic Technology in Quality and Safety of Agricultural Products and Foods

edited by

Yasuhiro Date

submission deadline 30 Nov 2024 | 5 articles | Viewed by 5070 | Submission Open

Keywords: metabolomics; metabolic profiling; metabolic fingerprinting; foodomics; nuclear magnetic resonance spectroscopy; mass spectrometry; multivariate analysis; machine learning

(This special issue belongs to the Section Food Metabolomics)

Nutritional Epidemiology and Metabolic Disorders

edited by

Kijoon Kim

and

Sanggil Lee

submission deadline 30 Nov 2024 | 3 articles | Viewed by 4562 | Submission Open

Keywords: nutritional epidemiology; antioxidants; medicinal herbs; functional ingredients; public health

(This special issue belongs to the Section Nutrition and Metabolism)

Impact of Exercise on Energy and Muscle Metabolism

edited by

Sebastian Gehlert

submission deadline 30 Nov 2024 | 1 articles | Viewed by 2334 | Submission Open

Keywords: muscle fibers; exercise metabolism; skeletal muscle adaptation; exercise performance; mitochondrial adaptation; exercise intensity and skeletal muscle metabolism; nutrition and exercise metabolism

(This special issue belongs to the Section Cell Metabolism)

Metabolomics in Human Diseases and Health

edited by Dimitris Kounatidis and

Iordanis Mourouzis

submission deadline 30 Nov 2024 | 2 articles | Viewed by 2243 | Submission Open

Keywords: metabolomics; NAFLD; biomarkers; obesity; mass spectrometry; NMR spectroscopy; diabetes mellitus; cancer; cardiovascular diseases; neurodegenerative diseases

(This special issue belongs to the Section Advances in Metabolomics)

Newborn Metabolomic Profile

edited by

Giuseppe De Bernardo

, Maurizio Giordano,

Giuseppe Buonocore

and

Serafina Perrone

submission deadline 30 Nov 2024 | 1 articles | Viewed by 2231 | Submission Open

Keywords: newborn metabolomic; inborn errors of metabolism; personalized medicine; pathophysiology mechanism; maternal nutrition; breastfeeding; pregnancy; assisted fertilization; diagnostic markers; therapeutic strategies

(This special issue belongs to the Section Advances in Metabolomics)

Metabolomics: An Emerging Potential Approach to Study Critical Illnesses, 2nd Edition

edited by

Helen G. Gika

and Pousinis Petros

submission deadline 30 Nov 2024 | 2 articles | Viewed by 2146 | Submission Open

Keywords: metabolomics; metabolic phenotype; critical illness; sepsis precision medicine; pharmacometabolomics

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Skeletal Muscle Fiber Phenotype as Determinant of Metabolism and Function in Health and Disease

edited by Christos Katsanos and

Walter Wahli

submission deadline 30 Nov 2024 | 1 articles | Viewed by 2080 | Submission Open

Keywords: muscle fiber types; muscle fiber characteristics; myosin heavy chain; slow and fast muscle fibers; muscle composition; muscle function; muscle disorders; muscle-related diseases; muscle fiber plasticity

(This special issue belongs to the Section Cell Metabolism)

Application of Metabolomics in Food Fermentation

edited by

John Kapolos

, Athanasia Koliadima and

Konstantinos Papadimitriou

submission deadline 30 Nov 2024 | 1 articles | Viewed by 1395 | Submission Open

Keywords: fermented foods; metabolomics; targeted metabolomics; untargeted metabolomics; microorganisms; mass spectrometry; yogurt; cheese; beer; wine; fermented vegetables; fermented meet

(This special issue belongs to the Section Food Metabolomics)

Metabolism of Bioactives and Natural Products

edited by Kamila Misiakiewicz-Has, Barbara Wiszniewska and

Sylwia Rzeszotek

submission deadline 30 Nov 2024 | Viewed by 414 | Submission Open

Keywords: natural products; bioactive; medicinal plants; phytochemicals; isoflavones; triterpenes; coumarins; alkaloids; prebiotics; carotenoids; polyphenols; organosulfur compounds

(This special issue belongs to the Section Nutrition and Metabolism)

Advances in Gas Chromatography–Mass Spectrometry-Based Targeted Metabolomics

edited by

David P. De Souza

and Sheik Nadeem Elahee Doomun

submission deadline 30 Nov 2024 | Viewed by 357 | Submission Open

Keywords: GC-MS; GC-QQQ; targeted metabolomics; polar metabolites; volatile organic compounds; stable isotope labelling; biomedical; agribio; environmental

(This special issue belongs to the Section Advances in Metabolomics)

The Role of Gut Microbes in Metabolism Regulation: 2nd Edition

edited by

Zhengrong Yuan

, Haolin Zhang and Zhihao Jia

submission deadline 30 Nov 2024 | Viewed by 243 | Submission Open

Keywords: gut microbes; metabolomics; energy homeostasis; metabolic disease; microbial regulation; host interactions; intestinal crosstalk

(This special issue belongs to the Section Integrative Metabolomics)

Metabolomic Insights: Interplay between Metabolism and Immune Response in Cancer

edited by

Dimitra Rafailia Bakaloudi

submission deadline 30 Nov 2024 | Viewed by 226 | Submission Open

Keywords: metabolites; metabolism; cancer; immune response; immunotherapy; immunometabolism

(This special issue belongs to the Section Cell Metabolism)

NMR-Metabolomics in Peptide and Antibody Drug Discovery

edited by

Michela Buonocore

Anna Maria D’Ursi

Angelo Santoro

and Carmen Marino

submission deadline 30 Nov 2024 | Viewed by 193 | Submission Open

Keywords: NMR metabolomics; peptides; antibodies; drug discovery; metabolomic profiles; biomarkers; mechanisms of action

(This special issue belongs to the Section Pharmacology and Drug Metabolism)

Integrated Targeted and Non-targeted Omics Platforms for the Analysis of the Environmental Exposome

edited by Lapo Renai and

Massimo Del Bubba

submission deadline 30 Nov 2024 | Viewed by 180 | Submission Open

Keywords: chromatography; high-resolution mass spectrometry; exposomics; chemicals of environmental concern; data analysis; integrated platforms; chemical databases

(This special issue belongs to the Section Environmental Metabolomics)

Cardiometabolic Disorders in Women

edited by

Timothy O'Toole

submission deadline 30 Nov 2024 | Viewed by 153 | Submission Open

Keywords: cardiometabolic disorders; cardiovascular diseases; women

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Nutrition and Metabolism in Acquired Brain Injury

edited by

Olivia Di Vincenzo

submission deadline 30 Nov 2024 | Viewed by 141 | Submission Open

Keywords: nutritional status; malnutrition; risk of malnutrition; undernutrition; body composition; food intake; metabolism; neurological diseases; stroke; rehabilitation

(This special issue belongs to the Section Nutrition and Metabolism)

Insights into Metabolism, Diagnostics and Therapeutics of Cancer and Tumor Microenvironment by NMR Spectroscopy

edited by

Shivanand M. Pudakalakatti

and

Pratip K. Bhattacharya

submission deadline 1 Dec 2024 | 2 articles | Viewed by 3259 | Submission Open

Keywords: cancer metabolism; early diagnosis; therapeutic intervention; NMR spectroscopy; instrument development; pulse sequence design; metabolites; software for metabolomics

(This special issue belongs to the Section Integrative Metabolomics)

Metabolomics in Neurodegenerative Diseases

edited by Stewart Francis Graham, Nazia M. Saiyed and Ali Yilmaz

submission deadline 5 Dec 2024 | 3 articles | Viewed by 4674 | Submission Open

Keywords: neurodegenerative disease; Alzheimer’ s disease; Parkinson’ s disease; Huntington’ s disease; ALS; neurodegeneration; biomarkers; metabolism; etiology; pathophysiology; biochemistry

(This special issue belongs to the Section Cell Metabolism)

Profiling of Bone Marrow Adipose Tissue Cells and Metabolism

edited by

Drenka Trivanovic

and

Nina Krako Jakovljević

submission deadline 5 Dec 2024 | Viewed by 139 | Submission Open

Keywords: bone marrow adipose tissue; adipocytes; mitochondria; lipids; nutrition; cancer; hematopoiesis; skeletal system; aging

(This special issue belongs to the Section Cell Metabolism)

Functional Foods and Natural Bioactive Compounds: Strategies to Face Metabolic Syndrome and Related Non-communicable Diseases

edited by

Paola Gauffin-Cano

, Sebastián Torres and

Roxana Medina

submission deadline 15 Dec 2024 | 1 articles | Viewed by 1156 | Submission Open

Keywords: functional foods; bioactive compounds; fermented foods; fermented beverages; fermented vegetable foods; probiotics; prebiotics; synbiotics; postbiotics; metabolic syndrome; non-communicable diseases

(This special issue belongs to the Section Nutrition and Metabolism)

Investigation of the Metabolic Mechanisms Underlying Breast Cancer: Navigating from Diagnosis to Survivorship

edited by Hongjin Li

submission deadline 15 Dec 2024 | 1 articles | Viewed by 669 | Submission Open

Keywords: breast cancer; metabolomics; biomarker; diagnosis; tumor; survivorship; treatment; data analysis

(This special issue belongs to the Section Advances in Metabolomics)

Puberty and the Metabolic Syndrome

edited by Banu Aydin and Stephen J. Winters

submission deadline 15 Dec 2024 | Viewed by 149 | Submission Open

Keywords: puberty; rapid growth; obesity; insulin resistance; metabolic syndrome; polycystic ovary syndrome; cardiovascular disease; diabetes; gonadotropins; sex hormones; sex hormone binding globulin

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

New Fertilizer and Industrial Microbial Technology Based on Microbial Metabolites, 2nd Edition

edited by

Nan Gao

submission deadline 15 Dec 2024 | Viewed by 109 | Submission Open

Keywords: new fertilizer; industrial microbial technology; microbial metabolites; metabolic networks; abiotic stress adaption; plant-growth-promoting rhizobacteria

(This special issue belongs to the Section Microbiology and Ecological Metabolomics)

Molecular Mechanisms in Cancer, Cardiovascular and Metabolic Diseases: Potential Therapies and Treatments

edited by

Alex Cleber Improta-Caria

submission deadline 18 Dec 2024 | 2 articles | Viewed by 3063 | Submission Open

Keywords: molecular mechanisms; cancer; cardiovascular diseases; metabolic diseases; treatments

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

Exploring Pathological Mechanisms in Obesity, Diabetes, and Metabolic Syndrome

edited by

Tiemin Liu

Hongmei Yan

and

Qiongyue Zhang

submission deadline 20 Dec 2024 | 3 articles | Viewed by 3663 | Submission Open

Keywords: metabolic diseases: obesity; diabetes; NAFLD; MAFLD; NASH; metabolic syndrome; etc.; multi-omics: metabolomics; lipidomics; proteomics; etc.; pathogenesis: genetic predispositions; lifestyle factors; microbiome and environmental exposures; etc.

(This special issue belongs to the Section Endocrinology and Clinical Metabolic Research)

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