Interactions between Probiotics, the Gut Microbiome, and Immunity
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Prebiotics and Probiotics".
Deadline for manuscript submissions: 15 February 2025 | Viewed by 26
Special Issue Editor
Interests: ARDS; asthma; COPD; COVID-19; probiotic bacteria; anti-inflammatory therapy
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Probiotics modulate the immune system from the gut-associated lymphoid tissue. In the intestinal microenvironment, dendritic cells recognize the probiotic and thus secrete cytokines with the ability to induce the polarization of naive T cells toward the population of Treg cells secreting IL-10. Both Treg cells and the secretion of anti-inflammatory IL-10 are driven to lymphoid tissue in distant organs to attenuate the pro-inflammatory response. In this context, the immune response is crucial for the anti-inflammatory action of probiotics. In this scenario, probiotic-rich foods in the diet or taking probiotic supplements can promote a healthy and balanced intestinal microbiota, reduce the colonization of antibiotic-resistant bacterial populations, and modulate the immune system. In that regard, the investigation of the bacterial population in the gut microbiota is critical to understanding the influence of intestinal dysbiosis on inflammatory chronic disease. Thus, new studies addressing both the action mechanisms of probiotic agents on the immune response and the evaluation of the gut microbiota are necessary. For this reason, the present Special Issue welcomes authors to submit studies that address the following topics:
- Chronic inflammatory diseases, the gut microbiota, and the immune response.
Dr. Flávio Aimbire Soares de Carvalho
Guest Editor
Manuscript Submission Information
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Keywords
- chronic inflammatory disease
- gut microbiota
- immune response
- anti-inflammatory response
- action mechanism
- cell signaling
