Search for Articles:
Title / Keyword
Author / Affiliation / Email
Journal
Article Type
 
 
Advanced Search
 
Section
Special Issue
Volume
Issue
Number
Page
 
9.2
4.8
Journals
Nutrients
Special Issues
Body Composition and Nutritional Status in Cancer Patients
nutrients-logo
Submit to Special Issue Submit Abstract to Special Issue Review for Nutrients Propose a Special Issue

Journal Menu

► Journal Menu

Journal Browser

► Journal Browser
share announcement

Body Composition and Nutritional Status in Cancer Patients

A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".

Deadline for manuscript submissions: 15 May 2025 | Viewed by 2247

Special Issue Editors

Dr. Annarita Pecchi

E-Mail Website
Guest Editor
Radiology Department, Modena University Hospital, University of Modena and Reggio Emilia, 41124 Modena, Italy
Interests: body-composition; nutritional status; breast, pancreas and liver imaging; oncological imaging; AI and radiomics analysis from radiological imaging
Dr. Giulia Besutti

E-Mail Website
Guest Editor
1. Radiology Unit, Azienda USL-IRCCS Reggio Emilia, 42123 Reggio Emilia, Italy
2. Department of Medical and Surgical Sciences, University of Modena and Reggio Emilia, 41124 Modena, Italy
Interests: computed tomography; magnetic resonance; diffusion magnetic resonance imaging; pancreatic cancer
Special Issues, Collections and Topics in MDPI journals
Dr. Federico Piacentini

E-Mail Website
Guest Editor
Oncology Department, Modena University Hospital, University of Modena and Reggio Emilia, 41124 Modena, Italy
Interests: biochemistry, genetics and molecular biology; breast cancer

Special Issue Information

Dear Colleagues,

In recent years, diagnostic imaging in cancer patients has become an important tool not only for providing diagnostic and follow-up information regarding cancer disease but also to know the body composition of the cancer patient. In particular, it is possible through CT and MR imaging to have quantitative and qualitative information regarding the muscle and adipose compartments (subcutaneous and visceral) and to define the presence of conditions such as sarcopenic obesity that may represent a risk factor of cancer diseases. Body composition seems to be important not only in the etiopathogenesis of cancer diseases but also in the development of cancer treatment toxicity and in the response to treatment. Therefore, knowing the body composition of the cancer patient and analyzing its variation during the course of the oncological treatment is very important to be able to introduce corrective actions, especially nutritional and physical, that can improve the body composition, favoring the response to treatments and reducing toxicity. This issue aims to collect information on body composition and its relationships with cancer disease, also welcoming new innovative analysis methods through radiomics and deep learning and to correlate body composition with nutritional aspects and interventions.

Dr. Annarita Pecchi
Dr. Giulia Besutti
Dr. Federico Piacentini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Nutrients is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • body composition
  • adipose tissue
  • sarcopenic obesity
  • oncological disease
  • nutritional asset

Benefits of Publishing in a Special Issue

  • Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
  • Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
  • Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
  • External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
  • e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.

Further information on MDPI's Special Issue polices can be found here.

Published Papers (3 papers)

Download All Papers
Order results
Result details
Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:

Research

Jump to: Other

13 pages, 292 KiB  
Article
Nutritional Status of Patients with Neoplasms Undergoing Ambulatory Chemotherapy and Associated Factors
by Luiz Claudio Barreto Silva Neto, Oscar Geovanny Enriquez-Martinez, Wesley Rocha Grippa, Julia Anhoque Cavalcanti Marcarini, Thayná Borges Santos, Nina Bruna de Souza Mawandji, Karoline Neumann Gomes, Sara Isabel Pimentel de Carvalho Schuab, Etreo Junior Carneiro da Silva Minarini, Karolini Zuqui Nunes, Andressa Bolsoni-Lopes and Luís Carlos Lopes-Júnior
Nutrients 2025, 17(1), 168; https://doi.org/10.3390/nu17010168 - 2 Jan 2025
Viewed by 701
Abstract
Background/Objectives: Cancer, a leading cause of mortality globally and in Brazil, is influenced by environmental and behavioral factors, often linked to nutritional deficiencies such as low body mass index and muscle wasting, exacerbating prognostic outcomes and mortality rates. Timely nutritional interventions during chemotherapy [...] Read more.
Background/Objectives: Cancer, a leading cause of mortality globally and in Brazil, is influenced by environmental and behavioral factors, often linked to nutritional deficiencies such as low body mass index and muscle wasting, exacerbating prognostic outcomes and mortality rates. Timely nutritional interventions during chemotherapy are pivotal, necessitating continuous nutritional assessment for effective patient care management. This study aimed to assess the nutritional status of non-metastatic cancer patients undergoing chemotherapy and identify factors influencing their nutritional status. Patient evaluation involved sociodemographic data, clinical profiles, anthropometric measurements, blood biochemical analyses, and nutritional status classification employing the Patient-Generated Subjective Global Assessment (PG-SGA) criteria. Statistical analysis was performed using R software. Results: Suspected malnutrition was identified in 5.81% of patients, with a significant association observed with gender, indicating a higher prevalence among men. Cancer stages II and III, along with a positive family history, correlated with heightened risk of malnutrition. Patients with suspected malnutrition exhibited older age, lower weight, body mass index (BMI), and reduced circumferences, underscoring the necessity of comprehensive nutritional assessment for optimized patient management during treatment. Conclusions: This study underscores a notable prevalence of malnutrition, particularly among patients with lower weight and BMI, affirming the reliability of PG-SGA criteria. Full article
(This article belongs to the Special Issue Body Composition and Nutritional Status in Cancer Patients)
14 pages, 585 KiB  
Article
Assessing Quality of Life with the Novel QLQ-CAX24 Questionnaire and Body Composition Parameters in Rectal Cancer Patients: A Single-Center Prospective Study
by Marco Cintoni, Marta Palombaro, Pauline Raoul, Giuditta Chiloiro, Angela Romano, Elisa Meldolesi, Flavia De Giacomo, Elena Leonardi, Gabriele Egidi, Futura Grassi, Gabriele Pulcini, Emanuele Rinninella, Esmeralda Capristo, Antonio Gasbarrini, Maria Antonietta Gambacorta and Maria Cristina Mele
Nutrients 2024, 16(24), 4277; https://doi.org/10.3390/nu16244277 - 11 Dec 2024
Viewed by 661
Abstract
Background: Patients with rectal cancer (RC) are at risk of developing cancer-related cachexia, a complex metabolic syndrome that can negatively impact quality of life (QoL), treatment tolerance, and clinical response. Objectives: The aim of the study was to explore the possible associations of [...] Read more.
Background: Patients with rectal cancer (RC) are at risk of developing cancer-related cachexia, a complex metabolic syndrome that can negatively impact quality of life (QoL), treatment tolerance, and clinical response. Objectives: The aim of the study was to explore the possible associations of the novel European Organization for Research and Treatment of Cancer QoL Questionnaire—Cancer Cachexia (EORTC QLQ-CAX24) scores with body composition parameters and physical performance in patients with locally advanced RC (LARC). Methods: This prospective observational study involved RC patients evaluated at the dedicated outpatient clinic of Clinical Nutrition at the Fondazione Policlinico Agostino Gemelli IRCCS. Patients with a confirmed diagnosis of LARC were enrolled between January and December 2023. The body composition parameters were measured using the preoperative computed tomography scan at the level of the third lumbar vertebra as well as using bioimpedance analysis before and after the radiotherapy treatment. QoL was measured by the EORTC QLQ-C30 and EORTC QLQ-CAX24 questionnaires. Results: A total of 56 RC patients were enrolled. Significant associations (p < 0.05) were found between EORTC QLQ-CAX24 values and the presence of cachexia, body composition, handgrip strength, and malnutrition diagnosis. Muscle mass was significatively also associated with EORTC QLQ-CAX24 results, suggesting a link between subjective perception of QoL and objectively measured body composition. Conclusions: The EORTC CAX24 questionnaire can be an effective tool for monitoring changes in cachexia status during radiotherapy, enabling early detection of cachexia-related complications and timely intervention. Full article
(This article belongs to the Special Issue Body Composition and Nutritional Status in Cancer Patients)
►▼ Show Figures

Figure 1

Other

Jump to: Research

10 pages, 777 KiB  
Brief Report
Controlling Nutritional Status (CONUT) Score as Prognostic Indicator in Stage IV Gastric Cancer with Chronic Intestinal Failure
by Konrad Matysiak, Aleksandra Hojdis and Magdalena Szewczuk
Nutrients 2024, 16(23), 4052; https://doi.org/10.3390/nu16234052 - 26 Nov 2024
Viewed by 634
Abstract
The management of chronic intestinal failure (CIF) secondary to advanced gastric cancer poses clinical challenges. This study explores the correlation between the Controlling Nutritional Status (CONUT) index and survival in patients with TNM stage IV gastric cancer on home parenteral nutrition (HPN). Methods: [...] Read more.
The management of chronic intestinal failure (CIF) secondary to advanced gastric cancer poses clinical challenges. This study explores the correlation between the Controlling Nutritional Status (CONUT) index and survival in patients with TNM stage IV gastric cancer on home parenteral nutrition (HPN). Methods: From 2015 to 2023, 410 patients (37% women, 63% men) with CIF due to advanced gastric cancer were assessed using CONUT scores, BMI, and biochemical tests. The Cox proportional hazards model was used to evaluate the impact of covariates on survival. Logistic regression categorized malnutrition levels by CONUT scores, with performance evaluated using precision, recall, and F1 scores. A p-value < 0.001 was statistically significant. Results: The CONUT scores were independent predictors of survival, with higher CONUT scores increasing mortality risk (HR = 2.073, 95% CI: 1.815–2.369, p < 0.001). The model achieved an overall accuracy of 71%, indicating correct classification for the majority of cases. Conclusions: CONUT scores are key predictors of survival in patients receiving HPN for CIF due to stage IV gastric cancer. Full article
(This article belongs to the Special Issue Body Composition and Nutritional Status in Cancer Patients)
►▼ Show Figures

Figure 1

Show export options expand_more Show export options expand_less
Select all
Export citation of selected articles as:
 
Displaying articles 1-3
Back to TopTop