Maternal Gestational Diabetes and Its Impact on Fetal Health
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Nutrition in Women".
Deadline for manuscript submissions: 25 April 2025 | Viewed by 87
Special Issue Editor
Special Issue Information
Dear Colleagues,
Gestational diabetes mellitus (GDM) affects up to 15 to 18% of pregnancies and is associated with risks to both mother and child. Consequently, GDM is one of the most important metabolic complications during pregnancy. The benefits of therapies aiming to reduce glucose levels in GDM pregnancies are well-established. Nonetheless, several critical research questions remain unresolved: Firstly, the Hyperglycemia and Adverse Pregnancy Outcomes (HAPO) Study indicated a direct association between maternal glucose concentrations during a 75g oral glucose tolerance test, conducted between the 24th and 32nd weeks of gestation, and adverse perinatal outcomes. It is, however, an ongoing debate regarding whether earlier testing and treatment (before 24 weeks of gestation) could diminish perinatal complications. Secondly, the frequent co-occurrence of fetal overgrowth and maternal obesity may be partially independent from maternal hyperglycemia. This phenomenon is likely driven by a higher degree of maternal insulin resistance in obese mothers; however, research in this area is limited. Thirdly, GDM presents a complex challenge in clinical management due to its phenotypic heterogeneity. This heterogeneity of GDM needs to be addressed with more detail to provide individualized treatment strategies. These research gaps should be addressed by this Special Issue.
Dr. Christian S. Göbl
Guest Editor
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Keywords
- gestational dibetes mellitus
- insulin resistance
- pregnancy
- fetal health
- hyperglycaemia
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