Coeliac Disease: Addressing Nutritional Challenges and Dietary Practices
A special issue of Nutrients (ISSN 2072-6643). This special issue belongs to the section "Clinical Nutrition".
Deadline for manuscript submissions: 15 April 2025 | Viewed by 1884
Special Issue Editor
Interests: coeliac disease; peptic ulcer; hiatus hernia; irritable bowel syndrome; ulcerative colitis; gastrointestinal infections; nutrition
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
Coeliac disease is a relatively common condition that affects 1–2% of subjects in Europe, North America, and most other countries. It involves a hypersensitivity to gluten proteins in wheat, rye, barley, and oats. The condition can present at any age, although most commonly in young children when they have been given gluten-containing foods as a part of their diet.
The condition is genetically inherited, particularly in people who carry either the HLA-DQ2 or HLA-DQ8 genes. The only accepted treatment is a lifelong gluten-free diet, avoiding foods that contain coeliac-toxic gluten proteins present in the cereals described above.
The diagnosis involves screening with blood tests for IgA and IgG tissue transglutaminase antibodies for gluten proteins or their partially broken down peptides, which is routinely undertaken in North America. Blood tests should also be performed for haematology, including haemoglobin levels and serum iron and folic acid levels. Once a diagnosis has been established, subjects should be referred to a dietitian, who is experienced in advising on how to initiate and follow a lifelong strict gluten-free diet. In the UK, gluten-free foods are available through family general practitioners, with prescriptions from the NHS that can be used to obtain gluten-free foods from local pharmacies. The UK Guidelines, as those followed in most other countries, stipulate subjects with coeliac disease should be followed up annually by someone who is experienced in the management of the condition, including gastroenterologists and dieticians who are experienced in the management of the condition. Particular care should be taken to screen young children of a parent who has coeliac disease, as the condition is genetically inherited.
For this Special Issue, we invite articles on improving the nutritional and dietary aspects of coeliac disease and other gluten-related diseases.
Prof. Dr. Paul J. Ciclitira
Guest Editor
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Keywords
- coeliac disease
- gluten-free diet
- nutrition
- genes
- gluten-sensitive enteropathy
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